Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50292705 ((25R)-25-Adamantyl-1alpha,25-dihydroxy-2-methylene...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Antagonist activity at VDR expressed in COS7 cells assessed as inhibition of 1,25-Dihydroxyvitamin D3-induced response by transient transcription ass... | J Med Chem 51: 5320-9 (2008) Article DOI: 10.1021/jm8004477 BindingDB Entry DOI: 10.7270/Q28C9W2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin D3 receptor (Homo sapiens (Human)) | BDBM50292705 ((25R)-25-Adamantyl-1alpha,25-dihydroxy-2-methylene...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1 | n/a | n/a | n/a | n/a |
Tokyo Medical and Dental University Curated by ChEMBL | Assay Description Agonist activity at VDR assessed as receptor transactivation by transient transcription assay | J Med Chem 51: 5320-9 (2008) Article DOI: 10.1021/jm8004477 BindingDB Entry DOI: 10.7270/Q28C9W2Z | |||||||||||
More data for this Ligand-Target Pair |