Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM93136'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM93136 (PDE5 Inhibitor, 6) Show SMILES CCn1c(O)c2Cc3c([nH]c4ccccc34)[C@H](c3ccc(OC)cc3OC)n2c1=O |r| Show InChI InChI=1S/C23H23N3O4/c1-4-25-22(27)18-12-16-14-7-5-6-8-17(14)24-20(16)21(26(18)23(25)28)15-10-9-13(29-2)11-19(15)30-3/h5-11,21,24,27H,4,12H2,1-3H3/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars		n/a	n/a	720	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo					Assay Description PDE activity was measured using a modification of the IMAP fluorescence polarization phosphodiesterase assay from Molecular Devices. The assay was m...				International Journal of Medicinal Chemistry 2011: 1-9 (2011) BindingDB Entry DOI: 10.7270/Q21R6P59
					More data for this Ligand-Target Pair