Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM93141'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM93141 (PDE5 Inhibitor, 19) Show SMILES COc1ccc([C@@H]2c3[nH]c4ccccc4c3Cc3c(O)n(CC=C)c(=S)n23)c(OC)c1 |r| Show InChI InChI=1S/C24H23N3O3S/c1-4-11-26-23(28)19-13-17-15-7-5-6-8-18(15)25-21(17)22(27(19)24(26)31)16-10-9-14(29-2)12-20(16)30-3/h4-10,12,22,25,28H,1,11,13H2,2-3H3/t22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars		n/a	n/a	560	n/a	n/a	n/a	n/a	n/a	n/a
German University in Cairo					Assay Description PDE activity was measured using a modification of the IMAP fluorescence polarization phosphodiesterase assay from Molecular Devices. The assay was m...				International Journal of Medicinal Chemistry 2011: 1-9 (2011) BindingDB Entry DOI: 10.7270/Q21R6P59
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