Compile Data Set for Download or QSAR

Found 10 hits of ic50 for monomerid = 18353   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat))	BDBM18353 ((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...) Show SMILES CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO Show InChI InChI=1S/C7H15NO4/c1-8-2-5(10)7(12)6(11)4(8)3-9/h4-7,9-12H,2-3H2,1H3/t4-,5+,6-,7-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of Sucrase in rat intestinal brush border membranes by D-glucose oxidase-peroxidase method				J Med Chem 38: 2349-56 (1995) BindingDB Entry DOI: 10.7270/Q2N878T0
					More data for this Ligand-Target Pair
Sucrase-isomaltase, intestinal (Rattus norvegicus (Rat))	BDBM18353 ((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...) Show SMILES CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO Show InChI InChI=1S/C7H15NO4/c1-8-2-5(10)7(12)6(11)4(8)3-9/h4-7,9-12H,2-3H2,1H3/t4-,5+,6-,7-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of Sucrase in rat intestinal brush border membranes by D-glucose oxidase-peroxidase method				J Med Chem 38: 2349-56 (1995) BindingDB Entry DOI: 10.7270/Q2N878T0
					More data for this Ligand-Target Pair
Maltase-glucoamylase (Homo sapiens (Human))	BDBM18353 ((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...) Show SMILES CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO Show InChI InChI=1S/C7H15NO4/c1-8-2-5(10)7(12)6(11)4(8)3-9/h4-7,9-12H,2-3H2,1H3/t4-,5+,6-,7-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of Glycosidases (maltase) in rat intestinal brush border membranes by D-glucose oxidase-peroxidase method maltase				J Med Chem 38: 2349-56 (1995) BindingDB Entry DOI: 10.7270/Q2N878T0
					More data for this Ligand-Target Pair
Protein-lysine 6-oxidase (Homo sapiens (Human))	BDBM18353 ((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...) Show SMILES CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO Show InChI InChI=1S/C7H15NO4/c1-8-2-5(10)7(12)6(11)4(8)3-9/h4-7,9-12H,2-3H2,1H3/t4-,5+,6-,7-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	4.5	37
Hokuriku University					Assay Description Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...				Bioorg Med Chem 14: 7736-44 (2006) Article DOI: 10.1016/j.bmc.2006.08.003 BindingDB Entry DOI: 10.7270/Q2BZ649B
					More data for this Ligand-Target Pair
Lactase/phlorizin hydrolase (Rattus norvegicus)	BDBM18353 ((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...) Show SMILES CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO Show InChI InChI=1S/C7H15NO4/c1-8-2-5(10)7(12)6(11)4(8)3-9/h4-7,9-12H,2-3H2,1H3/t4-,5+,6-,7-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of Glycosidases (lactase)in rat intestinal brush border membranes by D-glucose oxidase-peroxidase method				J Med Chem 38: 2349-56 (1995) BindingDB Entry DOI: 10.7270/Q2N878T0
					More data for this Ligand-Target Pair
Trehalase (Rattus norvegicus)	BDBM18353 ((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...) Show SMILES CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO Show InChI InChI=1S/C7H15NO4/c1-8-2-5(10)7(12)6(11)4(8)3-9/h4-7,9-12H,2-3H2,1H3/t4-,5+,6-,7-/m1/s1	Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of Glycosidases (trehalase)in rat intestinal brush border membranes by D-glucose oxidase-peroxidase method				J Med Chem 38: 2349-56 (1995) BindingDB Entry DOI: 10.7270/Q2N878T0
					More data for this Ligand-Target Pair
Alpha-mannosidase 2 (Rattus norvegicus)	BDBM18353 ((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...) Show SMILES CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO Show InChI InChI=1S/C7H15NO4/c1-8-2-5(10)7(12)6(11)4(8)3-9/h4-7,9-12H,2-3H2,1H3/t4-,5+,6-,7-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	<5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of golgi Alpha-mannosidase II in rat liver				J Med Chem 38: 2349-56 (1995) BindingDB Entry DOI: 10.7270/Q2N878T0
					More data for this Ligand-Target Pair
Lysosomal acid glucosylceramidase (Homo sapiens (Human))	BDBM18353 ((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...) Show SMILES CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO Show InChI InChI=1S/C7H15NO4/c1-8-2-5(10)7(12)6(11)4(8)3-9/h4-7,9-12H,2-3H2,1H3/t4-,5+,6-,7-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	5.5	37
Hokuriku University					Assay Description Enzyme activity was determined as the production of fluorescent 4-MU from the substrate. The fluorescence was measured (excitation 362 nm, emission 4...				Bioorg Med Chem 14: 7736-44 (2006) Article DOI: 10.1016/j.bmc.2006.08.003 BindingDB Entry DOI: 10.7270/Q2BZ649B
					More data for this Ligand-Target Pair
Alpha-mannosidase 2C1 (Rattus norvegicus)	BDBM18353 ((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...) Show SMILES CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO Show InChI InChI=1S/C7H15NO4/c1-8-2-5(10)7(12)6(11)4(8)3-9/h4-7,9-12H,2-3H2,1H3/t4-,5+,6-,7-/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of soluble Alpha-mannosidase II in rat liver				J Med Chem 38: 2349-56 (1995) BindingDB Entry DOI: 10.7270/Q2N878T0
					More data for this Ligand-Target Pair
Alpha-mannosidase (Rattus norvegicus)	BDBM18353 ((2R,3R,4R,5S)-2-(hydroxymethyl)-1-methylpiperidine...) Show SMILES CN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO Show InChI InChI=1S/C7H15NO4/c1-8-2-5(10)7(12)6(11)4(8)3-9/h4-7,9-12H,2-3H2,1H3/t4-,5+,6-,7-/m1/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Hokuriku University Curated by ChEMBL					Assay Description Inhibition of lysosomal Alpha-mannosidase II in rat liver				J Med Chem 38: 2349-56 (1995) BindingDB Entry DOI: 10.7270/Q2N878T0
					More data for this Ligand-Target Pair