Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken)) | BDBM234843 (US9353116, 3) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 111 | n/a | n/a | n/a | n/a | 8.0 | n/a |
The Regents of the University of California US Patent | Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat... | US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken)) | BDBM234848 (US9353116, 5) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 145 | n/a | n/a | n/a | n/a | 8.0 | n/a |
The Regents of the University of California US Patent | Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat... | US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken)) | BDBM50403061 (CHEMBL2216823 | US9353116, 9) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 150 | n/a | n/a | n/a | n/a | 8.0 | n/a |
The Regents of the University of California US Patent | Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat... | US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken)) | BDBM234858 (US9353116, 17) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 196 | n/a | n/a | n/a | n/a | 8.0 | n/a |
The Regents of the University of California US Patent | Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat... | US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken)) | BDBM234844 (US9353116, 13) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | US Patent | n/a | n/a | 338 | n/a | n/a | n/a | n/a | 8.0 | n/a |
The Regents of the University of California US Patent | Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat... | US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken)) | BDBM234845 (US9353116, 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 419 | n/a | n/a | n/a | n/a | 8.0 | n/a |
The Regents of the University of California US Patent | Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat... | US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken)) | BDBM234861 (US9353116, 20) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 560 | n/a | n/a | n/a | n/a | 8.0 | n/a |
The Regents of the University of California US Patent | Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat... | US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken)) | BDBM234857 (US9353116, 16) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 618 | n/a | n/a | n/a | n/a | 8.0 | n/a |
The Regents of the University of California US Patent | Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat... | US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken)) | BDBM234849 (US9353116, 6) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 817 | n/a | n/a | n/a | n/a | 8.0 | n/a |
The Regents of the University of California US Patent | Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat... | US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken)) | BDBM234860 (US9353116, 19 | US9353116, Fig. 16, Compound 1) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
The Regents of the University of California US Patent | Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat... | US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken)) | BDBM234859 (US9353116, 18) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.66E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
The Regents of the University of California US Patent | Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat... | US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken)) | BDBM234852 (US9353116, 10) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.76E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
The Regents of the University of California US Patent | Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat... | US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken)) | BDBM234850 (US9353116, 7) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.76E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
The Regents of the University of California US Patent | Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat... | US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken)) | BDBM234856 (US9353116, 15) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.16E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
The Regents of the University of California US Patent | Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat... | US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken)) | BDBM234853 (US9353116, 11) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB US Patent | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
The Regents of the University of California US Patent | Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat... | US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken)) | BDBM234855 (US9353116, 14) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 4.52E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
The Regents of the University of California US Patent | Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat... | US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken)) | BDBM234851 (US9353116, 8) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
The Regents of the University of California US Patent | Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat... | US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken)) | BDBM234847 (US9353116, 4) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
The Regents of the University of California US Patent | Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat... | US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken)) | BDBM234846 (US9353116, 2) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
The Regents of the University of California US Patent | Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat... | US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proto-oncogene tyrosine-protein kinase Src [251-533,T338C] (Gallus gallus (Chicken)) | BDBM234854 (US9353116, 12) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
The Regents of the University of California US Patent | Assay Description In vitro kinase assays for c-Src variants were performed in 50 mM Tris (pH 8.0), 10 mM MgCl2 and 1 mg/mL BSA. When obtaining kinetic parameters (kcat... | US Patent US9353116 (2016) BindingDB Entry DOI: 10.7270/Q2V123N7 | |||||||||||
More data for this Ligand-Target Pair |