Compile Data Set for Download or QSAR

Found 363 hits of ic50 data for polymerid = 1015   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM474989 (US10849901, Compound 39 | US10953012, Example 1) Show SMILES Cc1nn2c([nH]c(cc2=O)-c2ccc(cc2)[N+]([O-])=O)c1-c1ccc(Cl)cc1 Show InChI InChI=1S/C19H13ClN4O3/c1-11-18(13-2-6-14(20)7-3-13)19-21-16(10-17(25)23(19)22-11)12-4-8-15(9-5-12)24(26)27/h2-10,21H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487173 (2-(4-Chloro-phenyl)-5-methyl-4H-pyrazolo[1,5-a]pyr...) Show SMILES Cc1cc(=O)n2nc(cc2[nH]1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C13H10ClN3O/c1-8-6-13(18)17-12(15-8)7-11(16-17)9-2-4-10(14)5-3-9/h2-7,15H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487174 (6-Benzyl-3-(4-chloro-phenyl)-5-methyl-4H-pyrazolo[...) Show SMILES Cc1[nH]c2c(cnn2c(=O)c1Cc1ccccc1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H16ClN3O/c1-13-17(11-14-5-3-2-4-6-14)20(25)24-19(23-13)18(12-22-24)15-7-9-16(21)10-8-15/h2-10,12,23H,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487175 (2-(3-Bromo-phenyl)-5-methyl-4H-pyrazolo[1,5-a]pyri...) Show SMILES Cc1cc(=O)n2nc(cc2[nH]1)-c1cccc(Br)c1 Show InChI InChI=1S/C13H10BrN3O/c1-8-5-13(18)17-12(15-8)7-11(16-17)9-3-2-4-10(14)6-9/h2-7,15H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487176 (2-Benzyl-3-(4-methoxy-phenyl)-5-phenyl-4H-pyrazolo...) Show SMILES COc1ccc(cc1)-c1c(Cc2ccccc2)nn2c1[nH]c(cc2=O)-c1ccccc1 Show InChI InChI=1S/C26H21N3O2/c1-31-21-14-12-20(13-15-21)25-23(16-18-8-4-2-5-9-18)28-29-24(30)17-22(27-26(25)29)19-10-6-3-7-11-19/h2-15,17,27H,16H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487177 (3-(4-Methoxy-phenyl)-2-methyl-5-phenyl-4H-pyrazolo...) Show SMILES COc1ccc(cc1)-c1c(C)nn2c1[nH]c(cc2=O)-c1ccccc1 Show InChI InChI=1S/C20H17N3O2/c1-13-19(15-8-10-16(25-2)11-9-15)20-21-17(12-18(24)23(20)22-13)14-6-4-3-5-7-14/h3-12,21H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM475045 (US10849901, Compound 95 | US10953012, Example 7) Show SMILES O=c1cc([nH]c2c(c(Cc3ccccc3)nn12)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C25H19N3O/c29-23-17-21(19-12-6-2-7-13-19)26-25-24(20-14-8-3-9-15-20)22(27-28(23)25)16-18-10-4-1-5-11-18/h1-15,17,26H,16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487179 (3-(4-Chloro-phenyl)-2-methyl-5-phenyl-4H-pyrazolo[...) Show SMILES Cc1nn2c([nH]c(cc2=O)-c2ccccc2)c1-c1ccc(Cl)cc1 Show InChI InChI=1S/C19H14ClN3O/c1-12-18(14-7-9-15(20)10-8-14)19-21-16(11-17(24)23(19)22-12)13-5-3-2-4-6-13/h2-11,21H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM50168142 (CHEMBL3716578 | US10849901, Compound 38 | US109530...) Show SMILES [O-][N+](=O)c1ccc(cc1)-c1cc(=O)n2nc(Cc3ccccc3)c(-c3ccc(Cl)cc3)c2[nH]1 Show InChI InChI=1S/C25H17ClN4O3/c26-19-10-6-18(7-11-19)24-22(14-16-4-2-1-3-5-16)28-29-23(31)15-21(27-25(24)29)17-8-12-20(13-9-17)30(32)33/h1-13,15,27H,14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM474979 (US10849901, Compound 29 | US10953012, Example 25) Show SMILES Clc1ccc(cc1)-c1c(Cc2ccccc2)nn2c1[nH]c(cc2=O)-c1ccccc1 Show InChI InChI=1S/C25H18ClN3O/c26-20-13-11-19(12-14-20)24-22(15-17-7-3-1-4-8-17)28-29-23(30)16-21(27-25(24)29)18-9-5-2-6-10-18/h1-14,16,27H,15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487184 (2-Benzyl-3-naphthalen-1-yl-5-phenyl-4H-pyrazolo[1,...) Show SMILES O=c1cc([nH]c2c(c(Cc3ccccc3)nn12)-c1cccc2ccccc12)-c1ccccc1 |(1.49,-3.93,;1.49,-2.39,;2.83,-1.62,;2.83,-.08,;1.49,.69,;.16,-.08,;-1.3,.39,;-2.21,-.85,;-3.75,-.85,;-4.52,-2.19,;-6.06,-2.19,;-6.83,-3.52,;-6.06,-4.85,;-4.52,-4.85,;-3.75,-3.52,;-1.3,-2.1,;.16,-1.62,;-1.7,1.88,;-.61,2.97,;-1.01,4.46,;-2.5,4.85,;-3.59,3.77,;-5.08,4.16,;-6.17,3.08,;-5.77,1.59,;-4.28,1.19,;-3.19,2.28,;4.16,.69,;5.5,-.08,;6.83,.69,;6.83,2.23,;5.5,3,;4.16,2.23,)| Show InChI InChI=1S/C29H21N3O/c33-27-19-25(22-13-5-2-6-14-22)30-29-28(24-17-9-15-21-12-7-8-16-23(21)24)26(31-32(27)29)18-20-10-3-1-4-11-20/h1-17,19,30H,18H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487185 (2-(4-Methoxy-benzyl)-3,5-diphenyl-4H-pyrazolo[1,5-...) Show SMILES COc1ccc(Cc2nn3c([nH]c(cc3=O)-c3ccccc3)c2-c2ccccc2)cc1 Show InChI InChI=1S/C26H21N3O2/c1-31-21-14-12-18(13-15-21)16-23-25(20-10-6-3-7-11-20)26-27-22(17-24(30)29(26)28-23)19-8-4-2-5-9-19/h2-15,17,27H,16H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487186 (2-Methyl-7-oxo-3,5-diphenyl-4,7-dihydro-pyrazolo[1...) Show SMILES Cc1nn2c([nH]c(-c3ccccc3)c(C#N)c2=O)c1-c1ccccc1 Show InChI InChI=1S/C20H14N4O/c1-13-17(14-8-4-2-5-9-14)19-22-18(15-10-6-3-7-11-15)16(12-21)20(25)24(19)23-13/h2-11,22H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487187 (5-(4-Methoxy-phenyl)-2-methyl-3-phenyl-4H-pyrazolo...) Show SMILES COc1ccc(cc1)-c1cc(=O)n2nc(C)c(-c3ccccc3)c2[nH]1 Show InChI InChI=1S/C20H17N3O2/c1-13-19(15-6-4-3-5-7-15)20-21-17(12-18(24)23(20)22-13)14-8-10-16(25-2)11-9-14/h3-12,21H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487188 (3-(4-Fluoro-phenyl)-2-methyl-5-phenyl-4H-pyrazolo[...) Show SMILES Cc1nn2c([nH]c(cc2=O)-c2ccccc2)c1-c1ccc(F)cc1 Show InChI InChI=1S/C19H14FN3O/c1-12-18(14-7-9-15(20)10-8-14)19-21-16(11-17(24)23(19)22-12)13-5-3-2-4-6-13/h2-11,21H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM50260215 (CHEMBL3717926 | US10953012, Example 16) Show SMILES COc1ccccc1-c1cc(=O)n2nc(C)c(-c3ccccc3)c2[nH]1 Show InChI InChI=1S/C20H17N3O2/c1-13-19(14-8-4-3-5-9-14)20-21-16(12-18(24)23(20)22-13)15-10-6-7-11-17(15)25-2/h3-12,21H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487191 (5-(4-Chloro-phenyl)-2-methyl-3-phenyl-4H-pyrazolo[...) Show SMILES Cc1nn2c([nH]c(cc2=O)-c2ccc(Cl)cc2)c1-c1ccccc1 Show InChI InChI=1S/C19H14ClN3O/c1-12-18(14-5-3-2-4-6-14)19-21-16(11-17(24)23(19)22-12)13-7-9-15(20)10-8-13/h2-11,21H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487192 (2-Benzyl-3-(4-chloro-phenyl)-5-propyl-4H-pyrazolo[...) Show SMILES CCCc1cc(=O)n2nc(Cc3ccccc3)c(-c3ccc(Cl)cc3)c2[nH]1 Show InChI InChI=1S/C22H20ClN3O/c1-2-6-18-14-20(27)26-22(24-18)21(16-9-11-17(23)12-10-16)19(25-26)13-15-7-4-3-5-8-15/h3-5,7-12,14,24H,2,6,13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487193 (2-Benzyl-5-methoxymethyl-3-(4-methoxy-phenyl)-4H-p...) Show SMILES COCc1cc(=O)n2nc(Cc3ccccc3)c(-c3ccc(OC)cc3)c2[nH]1 Show InChI InChI=1S/C22H21N3O3/c1-27-14-17-13-20(26)25-22(23-17)21(16-8-10-18(28-2)11-9-16)19(24-25)12-15-6-4-3-5-7-15/h3-11,13,23H,12,14H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487196 (3-(4-Chloro-phenyl)-2-methyl-5-propyl-4H-pyrazolo[...) Show SMILES CCCc1cc(=O)n2nc(C)c(-c3ccc(Cl)cc3)c2[nH]1 Show InChI InChI=1S/C16H16ClN3O/c1-3-4-13-9-14(21)20-16(18-13)15(10(2)19-20)11-5-7-12(17)8-6-11/h5-9,18H,3-4H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487177 (3-(4-Methoxy-phenyl)-2-methyl-5-phenyl-4H-pyrazolo...) Show SMILES COc1ccc(cc1)-c1c(C)nn2c1[nH]c(cc2=O)-c1ccccc1 Show InChI InChI=1S/C20H17N3O2/c1-13-19(15-8-10-16(25-2)11-9-15)20-21-17(12-18(24)23(20)22-13)14-6-4-3-5-7-14/h3-12,21H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487195 (2,5-Dibenzyl-3-phenyl-4H-pyrazolo[1,5-a]pyrimidin-...) Show SMILES O=c1cc(Cc2ccccc2)[nH]c2c(c(Cc3ccccc3)nn12)-c1ccccc1 Show InChI InChI=1S/C26H21N3O/c30-24-18-22(16-19-10-4-1-5-11-19)27-26-25(21-14-8-3-9-15-21)23(28-29(24)26)17-20-12-6-2-7-13-20/h1-15,18,27H,16-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487197 (5-Benzyl-3-(4-methoxy-phenyl)-2-methyl-4H-pyrazolo...) Show SMILES COc1ccc(cc1)-c1c(C)nn2c1[nH]c(Cc1ccccc1)cc2=O Show InChI InChI=1S/C21H19N3O2/c1-14-20(16-8-10-18(26-2)11-9-16)21-22-17(13-19(25)24(21)23-14)12-15-6-4-3-5-7-15/h3-11,13,22H,12H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487198 (2-Benzyl-3-(4-chloro-phenyl)-5-methoxymethyl-4H-py...) Show SMILES COCc1cc(=O)n2nc(Cc3ccccc3)c(-c3ccc(Cl)cc3)c2[nH]1 Show InChI InChI=1S/C21H18ClN3O2/c1-27-13-17-12-19(26)25-21(23-17)20(15-7-9-16(22)10-8-15)18(24-25)11-14-5-3-2-4-6-14/h2-10,12,23H,11,13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM474979 (US10849901, Compound 29 | US10953012, Example 25) Show SMILES Clc1ccc(cc1)-c1c(Cc2ccccc2)nn2c1[nH]c(cc2=O)-c1ccccc1 Show InChI InChI=1S/C25H18ClN3O/c26-20-13-11-19(12-14-20)24-22(15-17-7-3-1-4-8-17)28-29-23(30)16-21(27-25(24)29)18-9-5-2-6-10-18/h1-14,16,27H,15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487200 (2-Benzyl-3-(4-chlorophenyl)-6,7-dihydro-4H-cyclope...) Show SMILES Clc1ccc(cc1)-c1c(Cc2ccccc2)nn2c1[nH]c1CCCc1c2=O Show InChI InChI=1S/C22H18ClN3O/c23-16-11-9-15(10-12-16)20-19(13-14-5-2-1-3-6-14)25-26-21(20)24-18-8-4-7-17(18)22(26)27/h1-3,5-6,9-12,24H,4,7-8,13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487201 (3-(4-Chlorophenyl)-2-methyl-6,7-dihydro-4H-cyclope...) Show SMILES Cc1nn2c([nH]c3CCCc3c2=O)c1-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H14ClN3O/c1-9-14(10-5-7-11(17)8-6-10)15-18-13-4-2-3-12(13)16(21)20(15)19-9/h5-8,18H,2-4H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487202 (3-(4-Chloro-phenyl)-2,5-dimethyl-4H-pyrazolo[1,5-a...) Show SMILES Cc1nn2c([nH]c(C)cc2=O)c1-c1ccc(Cl)cc1 Show InChI InChI=1S/C14H12ClN3O/c1-8-7-12(19)18-14(16-8)13(9(2)17-18)10-3-5-11(15)6-4-10/h3-7,16H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487203 (2-(4-Chloro-phenyl)-5-methoxymethyl-4H-pyrazolo[1,...) Show SMILES COCc1cc(=O)n2nc(cc2[nH]1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C14H12ClN3O2/c1-20-8-11-6-14(19)18-13(16-11)7-12(17-18)9-2-4-10(15)5-3-9/h2-7,16H,8H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487204 (5-Isopropyl-2-(4-methoxy-phenyl)-3-phenyl-4H-pyraz...) Show SMILES COc1ccc(cc1)-c1nn2c([nH]c(cc2=O)C(C)C)c1-c1ccccc1 Show InChI InChI=1S/C22H21N3O2/c1-14(2)18-13-19(26)25-22(23-18)20(15-7-5-4-6-8-15)21(24-25)16-9-11-17(27-3)12-10-16/h4-14,23H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487205 (2-(4-Methoxy-benzyl)-5-methyl-3-phenyl-4H-pyrazolo...) Show SMILES COc1ccc(Cc2nn3c([nH]c(C)cc3=O)c2-c2ccccc2)cc1 Show InChI InChI=1S/C21H19N3O2/c1-14-12-19(25)24-21(22-14)20(16-6-4-3-5-7-16)18(23-24)13-15-8-10-17(26-2)11-9-15/h3-12,22H,13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487206 (6-Ethyl-2-(4-methoxy-benzyl)-5-methyl-3-phenyl-4H-...) Show SMILES CCc1c(C)[nH]c2c(c(Cc3ccc(OC)cc3)nn2c1=O)-c1ccccc1 Show InChI InChI=1S/C23H23N3O2/c1-4-19-15(2)24-22-21(17-8-6-5-7-9-17)20(25-26(22)23(19)27)14-16-10-12-18(28-3)13-11-16/h5-13,24H,4,14H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487207 (3-(4-Chloro-phenyl)-6-ethyl-2,5-dimethyl-4H-pyrazo...) Show SMILES CCc1c(C)[nH]c2c(c(C)nn2c1=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H16ClN3O/c1-4-13-9(2)18-15-14(10(3)19-20(15)16(13)21)11-5-7-12(17)8-6-11/h5-8,18H,4H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM475039 (US10849901, Compound 89 | US10953012, Example 34) Show SMILES O=c1cc(Cc2ccccc2)[nH]c2c(c(nn12)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C25H19N3O/c29-22-17-21(16-18-10-4-1-5-11-18)26-25-23(19-12-6-2-7-13-19)24(27-28(22)25)20-14-8-3-9-15-20/h1-15,17,26H,16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487209 (2,3-Diphenyl-6,7-dihydro-4H-cyclopenta[d]pyrazolo[...) Show SMILES O=c1c2CCCc2[nH]c2c(c(nn12)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C21H17N3O/c25-21-16-12-7-13-17(16)22-20-18(14-8-3-1-4-9-14)19(23-24(20)21)15-10-5-2-6-11-15/h1-6,8-11,22H,7,12-13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487210 ((7-oxo-2,3-diphenyl-4,7-dihydro-pyrazolo[1,5-a]pyr...) Show SMILES CCOC(=O)Cc1cc(=O)n2nc(c(-c3ccccc3)c2[nH]1)-c1ccccc1 Show InChI InChI=1S/C22H19N3O3/c1-2-28-19(27)14-17-13-18(26)25-22(23-17)20(15-9-5-3-6-10-15)21(24-25)16-11-7-4-8-12-16/h3-13,23H,2,14H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487215 (2-Methyl-3-phenyl-5-p-tolyl-4H-pyrazolo[1,5-a]pyri...) Show SMILES Cc1nn2c([nH]c(cc2=O)-c2ccc(C)cc2)c1-c1ccccc1 Show InChI InChI=1S/C20H17N3O/c1-13-8-10-15(11-9-13)17-12-18(24)23-20(21-17)19(14(2)22-23)16-6-4-3-5-7-16/h3-12,21H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487216 (3-(4-Fluoro-phenyl)-5-(4-methoxy-phenyl)-2-methyl-...) Show SMILES COc1ccc(cc1)-c1cc(=O)n2nc(C)c(-c3ccc(F)cc3)c2[nH]1 Show InChI InChI=1S/C20H16FN3O2/c1-12-19(14-3-7-15(21)8-4-14)20-22-17(11-18(25)24(20)23-12)13-5-9-16(26-2)10-6-13/h3-11,22H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487175 (2-(3-Bromo-phenyl)-5-methyl-4H-pyrazolo[1,5-a]pyri...) Show SMILES Cc1cc(=O)n2nc(cc2[nH]1)-c1cccc(Br)c1 Show InChI InChI=1S/C13H10BrN3O/c1-8-5-13(18)17-12(15-8)7-11(16-17)9-3-2-4-10(14)6-9/h2-7,15H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 1: One assay for purified hPASK activity utilizes the Kinase-Glo Luminescent Kinase Assay (Promega), which quantifies the amount of ATP remaini...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487219 (5-(4-Methoxyphenyl)-2-methyl-3-propylpyrazolo[1,5-...) Show SMILES CCCc1c(C)nn2c1[nH]c(cc2=O)-c1ccc(OC)cc1 Show InChI InChI=1S/C17H19N3O2/c1-4-5-14-11(2)19-20-16(21)10-15(18-17(14)20)12-6-8-13(22-3)9-7-12/h6-10,18H,4-5H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487220 (5-(4-Methoxyphenyl)-3-(pyridin-3-yl)pyrazolo[1,5-a...) Show SMILES COc1ccc(cc1)-c1cc(=O)n2ncc(-c3cccnc3)c2[nH]1 Show InChI InChI=1S/C18H14N4O2/c1-24-14-6-4-12(5-7-14)16-9-17(23)22-18(21-16)15(11-20-22)13-3-2-8-19-10-13/h2-11,21H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487221 (3-Benzyl-2-methyl-5-(quinolin-6-yl)pyrazolo[1,5-a]...) Show SMILES Cc1nn2c([nH]c(cc2=O)-c2ccc3ncccc3c2)c1Cc1ccccc1 Show InChI InChI=1S/C23H18N4O/c1-15-19(12-16-6-3-2-4-7-16)23-25-21(14-22(28)27(23)26-15)18-9-10-20-17(13-18)8-5-11-24-20/h2-11,13-14,25H,12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487222 (3-Benzyl-5-(1H-indol-6-yl)-2-methylpyrazolo[1,5-a]...) Show SMILES Cc1nn2c([nH]c(cc2=O)-c2ccc3cc[nH]c3c2)c1Cc1ccccc1 Show InChI InChI=1S/C22H18N4O/c1-14-18(11-15-5-3-2-4-6-15)22-24-20(13-21(27)26(22)25-14)17-8-7-16-9-10-23-19(16)12-17/h2-10,12-13,23-24H,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487223 (3-(3-Chlorobenzyl)-5-(benzo[d][1,3]dioxol-5-yl)-2-...) Show SMILES Cc1nn2c([nH]c(cc2=O)-c2ccc3OCOc3c2)c1Cc1cccc(Cl)c1 Show InChI InChI=1S/C21H16ClN3O3/c1-12-16(8-13-3-2-4-15(22)7-13)21-23-17(10-20(26)25(21)24-12)14-5-6-18-19(9-14)28-11-27-18/h2-7,9-10,23H,8,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487224 (3-(4-Chlorobenzyl)-5-(benzo[d][1,3]dioxol-5-yl)-2-...) Show SMILES Cc1nn2c([nH]c(cc2=O)-c2ccc3OCOc3c2)c1Cc1ccc(Cl)cc1 Show InChI InChI=1S/C21H16ClN3O3/c1-12-16(8-13-2-5-15(22)6-3-13)21-23-17(10-20(26)25(21)24-12)14-4-7-18-19(9-14)28-11-27-18/h2-7,9-10,23H,8,11H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487225 (3-(4-Fluorophenyl)-2-methyl-5-(pyridin-3-yl)pyrazo...) Show SMILES Cc1nn2c([nH]c(cc2=O)-c2cccnc2)c1-c1ccc(F)cc1 Show InChI InChI=1S/C18H13FN4O/c1-11-17(12-4-6-14(19)7-5-12)18-21-15(9-16(24)23(18)22-11)13-3-2-8-20-10-13/h2-10,21H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487226 (3-(4-Fluorophenyl)-5-(pyridin-2-yl)pyrazolo[1,5-a]...) Show SMILES Fc1ccc(cc1)-c1cnn2c1[nH]c(cc2=O)-c1ccccn1 Show InChI InChI=1S/C17H11FN4O/c18-12-6-4-11(5-7-12)13-10-20-22-16(23)9-15(21-17(13)22)14-3-1-2-8-19-14/h1-10,21H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487227 (5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-3-(4-fluor...) Show SMILES Cc1nn2c([nH]c(cc2=O)-c2ccc3OCCOc3c2)c1-c1ccc(F)cc1 Show InChI InChI=1S/C21H16FN3O3/c1-12-20(13-2-5-15(22)6-3-13)21-23-16(11-19(26)25(21)24-12)14-4-7-17-18(10-14)28-9-8-27-17/h2-7,10-11,23H,8-9H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487228 (5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-3-(3-metho...) Show SMILES COc1cccc(c1)-c1cnn2c1[nH]c(cc2=O)-c1ccc2OCCOc2c1 Show InChI InChI=1S/C21H17N3O4/c1-26-15-4-2-3-13(9-15)16-12-22-24-20(25)11-17(23-21(16)24)14-5-6-18-19(10-14)28-8-7-27-18/h2-6,9-12,23H,7-8H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair
PAS domain-containing serine/threonine-protein kinase [879-1323] (Homo sapiens (Human))	BDBM487229 (5-(Benzofuran-2-yl)-3-(pyridin-2-yl)pyrazolo[1,5-a...) Show SMILES O=c1cc([nH]c2c(cnn12)-c1ccccn1)-c1cc2ccccc2o1 Show InChI InChI=1S/C19H12N4O2/c24-18-10-15(17-9-12-5-1-2-7-16(12)25-17)22-19-13(11-21-23(18)19)14-6-3-4-8-20-14/h1-11,22H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
BioEnergenix LLC US Patent					Assay Description Table 2: Purified PASK (UniProt #Q96RG2; human recombinant N-terminal GST tagged construct, residues 879-1323) from insect cells (final concentration...				US Patent US10953012 (2021) BindingDB Entry DOI: 10.7270/Q22F7RJN
					More data for this Ligand-Target Pair

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