Compile Data Set for Download or QSAR

Found 5 hits of ic50 for UniProtKB: P19419   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ETS domain-containing protein Elk-1 (Homo sapiens (Human))	BDBM237214 (1-(4-Bromophenyl)-1-(4-hydroxy-3-methoxybenzyl)-3-...) Show SMILES COc1cc(CN(C(=O)Nc2ccccc2)c2ccc(Br)cc2)ccc1O Show InChI InChI=1S/C21H19BrN2O3/c1-27-20-13-15(7-12-19(20)25)14-24(18-10-8-16(22)9-11-18)21(26)23-17-5-3-2-4-6-17/h2-13,25H,14H2,1H3,(H,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University					Assay Description Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...				J Enzyme Inhib Med Chem 27: 708-14 (2012) Article DOI: 10.3109/14756366.2011.608665 BindingDB Entry DOI: 10.7270/Q2N015FS
					More data for this Ligand-Target Pair
ETS domain-containing protein Elk-1 (Homo sapiens (Human))	BDBM237225 (1-(4-Bromophenyl)-1-(4-hydroxy-3-methoxybenzyl)-3-...) Show SMILES COc1cc(CN(C(=S)Nc2ccccc2)c2ccc(Br)cc2)ccc1O Show InChI InChI=1S/C21H19BrN2O2S/c1-26-20-13-15(7-12-19(20)25)14-24(18-10-8-16(22)9-11-18)21(27)23-17-5-3-2-4-6-17/h2-13,25H,14H2,1H3,(H,23,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University					Assay Description Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...				J Enzyme Inhib Med Chem 27: 708-14 (2012) Article DOI: 10.3109/14756366.2011.608665 BindingDB Entry DOI: 10.7270/Q2N015FS
					More data for this Ligand-Target Pair
ETS domain-containing protein Elk-1 (Homo sapiens (Human))	BDBM237223 (1-(4-Fluorophenyl)-1-(4-hydroxy-3-methoxybenzyl)-3...) Show SMILES COc1cc(CN(C(=S)Nc2ccccc2)c2ccc(F)cc2)ccc1O Show InChI InChI=1S/C21H19FN2O2S/c1-26-20-13-15(7-12-19(20)25)14-24(18-10-8-16(22)9-11-18)21(27)23-17-5-3-2-4-6-17/h2-13,25H,14H2,1H3,(H,23,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University					Assay Description Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...				J Enzyme Inhib Med Chem 27: 708-14 (2012) Article DOI: 10.3109/14756366.2011.608665 BindingDB Entry DOI: 10.7270/Q2N015FS
					More data for this Ligand-Target Pair
ETS domain-containing protein Elk-1 (Homo sapiens (Human))	BDBM237222 (1-(4-Hydroxy-3-methoxybenzyl)-1-(4-methoxyphenyl)-...) Show SMILES COc1ccc(cc1)N(Cc1ccc(O)c(OC)c1)C(=S)Nc1ccccc1 Show InChI InChI=1S/C22H22N2O3S/c1-26-19-11-9-18(10-12-19)24(22(28)23-17-6-4-3-5-7-17)15-16-8-13-20(25)21(14-16)27-2/h3-14,25H,15H2,1-2H3,(H,23,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University					Assay Description Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...				J Enzyme Inhib Med Chem 27: 708-14 (2012) Article DOI: 10.3109/14756366.2011.608665 BindingDB Entry DOI: 10.7270/Q2N015FS
					More data for this Ligand-Target Pair
ETS domain-containing protein Elk-1 (Homo sapiens (Human))	BDBM237224 (1-(4-Chlorophenyl)-1-(4-hydroxy-3-methoxybenzyl)-3...) Show SMILES COc1cc(CN(C(=S)Nc2ccccc2)c2ccc(Cl)cc2)ccc1O Show InChI InChI=1S/C21H19ClN2O2S/c1-26-20-13-15(7-12-19(20)25)14-24(18-10-8-16(22)9-11-18)21(27)23-17-5-3-2-4-6-17/h2-13,25H,14H2,1H3,(H,23,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.47E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University					Assay Description Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...				J Enzyme Inhib Med Chem 27: 708-14 (2012) Article DOI: 10.3109/14756366.2011.608665 BindingDB Entry DOI: 10.7270/Q2N015FS
					More data for this Ligand-Target Pair