Compile Data Set for Download or QSAR

Found 3 hits of ic50 for UniProtKB: P18031   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 1 [1-321] (Homo sapiens (Human))	BDBM50391109 (CHEMBL179166 | Sodium orthovanadate (SOV) | Vanada...) Show SMILES [O-][V]([O-])([O-])=O Show InChI InChI=1S/4O.V/q;3*-1;	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	25.4	n/a	n/a	n/a	n/a	7.5	37
Chulalongkorn University					Assay Description PTP1B was diluted before the experiment to 1.2 μg/mL in Tris buffer, pH7.6 (10 mM Tris, 1.0 mM EDTA, 3.0 mM DTT, 0.01% w/v NaN3). The tested com...				J Enzyme Inhib Med Chem 28: 1067-72 (2013) Article DOI: 10.3109/14756366.2012.715286 BindingDB Entry DOI: 10.7270/Q2FN1530
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tyrosine-protein phosphatase non-receptor type 1 [1-321] (Homo sapiens (Human))	BDBM50146462 ((2E)-3-(2-hydroxyphenyl)-2-propenoic acid | (2E)-3...) Show SMILES OC(=O)\C=C\c1ccccc1O Show InChI InChI=1S/C9H8O3/c10-8-4-2-1-3-7(8)5-6-9(11)12/h1-6,10H,(H,11,12)/b6-5+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.38E+5	n/a	n/a	n/a	n/a	7.5	37
Chulalongkorn University					Assay Description PTP1B was diluted before the experiment to 1.2 μg/mL in Tris buffer, pH7.6 (10 mM Tris, 1.0 mM EDTA, 3.0 mM DTT, 0.01% w/v NaN3). The tested com...				J Enzyme Inhib Med Chem 28: 1067-72 (2013) Article DOI: 10.3109/14756366.2012.715286 BindingDB Entry DOI: 10.7270/Q2FN1530
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 [1-321] (Homo sapiens (Human))	BDBM4374 ((2E)-3-(4-hydroxyphenyl)prop-2-enoic acid | (2E)-3...) Show SMILES OC(=O)\C=C\c1ccc(O)cc1 Show InChI InChI=1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)/b6-3+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.68E+5	n/a	n/a	n/a	n/a	7.5	37
Chulalongkorn University					Assay Description PTP1B was diluted before the experiment to 1.2 μg/mL in Tris buffer, pH7.6 (10 mM Tris, 1.0 mM EDTA, 3.0 mM DTT, 0.01% w/v NaN3). The tested com...				J Enzyme Inhib Med Chem 28: 1067-72 (2013) Article DOI: 10.3109/14756366.2012.715286 BindingDB Entry DOI: 10.7270/Q2FN1530
					More data for this Ligand-Target Pair