Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase (Vibrio cholerae) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Istituto di Biochimica delle Proteine - CNR Curated by ChEMBL | Assay Description Inhibition of Flaveria bidentis recombinant CA by CO2 hydration assay | Bioorg Med Chem Lett 23: 4067-71 (2013) Article DOI: 10.1016/j.bmcl.2013.05.063 BindingDB Entry DOI: 10.7270/Q2HX1F27 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase (Vibrio cholerae) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florida Curated by ChEMBL | Assay Description Inhibition of Pseudomonas aeruginosa PAO1 type-2 beta-carbonic anhydrase psCA3 expressed in Escherichia coli Tuner BL21 (DE3) cells pre-incubated for... | Bioorg Med Chem 23: 4831-8 (2015) Article DOI: 10.1016/j.bmc.2015.05.029 BindingDB Entry DOI: 10.7270/Q20V8FK8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase (Vibrio cholerae) | BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Firenze Curated by ChEMBL | Assay Description Inhibition of Flaveria bidentis carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay | Bioorg Med Chem Lett 23: 6706-10 (2013) Article DOI: 10.1016/j.bmcl.2013.10.037 BindingDB Entry DOI: 10.7270/Q2XP76CZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase [110-330] (Flaveria bidentis (Coastal plain yellowtops)) | BDBM92494 (Citrate | SODIUM CITRATE) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | 4.14E+4 | -5.87 | n/a | n/a | n/a | n/a | n/a | 8.3 | 20 |
Istituto di Biostrutture e Bioimmagini-CNR | Assay Description Inhibition constants of carboxylate inhibitors against F. bidentis CA I were determined by a stopped flow CO2 hydration assay at 20 °C. | J Enzyme Inhib Med Chem 29: 500-4 (2014) Article DOI: 10.3109/14756366.2013.813942 BindingDB Entry DOI: 10.7270/Q2WD3ZGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase [110-330] (Flaveria bidentis (Coastal plain yellowtops)) | BDBM50159796 (2,3,5,6-F4-Benzoate | CHEMBL368444 | Sodium; 2,3,5...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | 5.12E+4 | -5.75 | n/a | n/a | n/a | n/a | n/a | 8.3 | 20 |
Istituto di Biostrutture e Bioimmagini-CNR | Assay Description Inhibition constants of carboxylate inhibitors against F. bidentis CA I were determined by a stopped flow CO2 hydration assay at 20 °C. | J Enzyme Inhib Med Chem 29: 500-4 (2014) Article DOI: 10.3109/14756366.2013.813942 BindingDB Entry DOI: 10.7270/Q2WD3ZGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase [110-330] (Flaveria bidentis (Coastal plain yellowtops)) | BDBM36181 (SODIUM BENZOATE | benzoate | benzoic acid | benzoi...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 6.45E+4 | -5.62 | n/a | n/a | n/a | n/a | n/a | 8.3 | 20 |
Istituto di Biostrutture e Bioimmagini-CNR | Assay Description Inhibition constants of carboxylate inhibitors against F. bidentis CA I were determined by a stopped flow CO2 hydration assay at 20 °C. | J Enzyme Inhib Med Chem 29: 500-4 (2014) Article DOI: 10.3109/14756366.2013.813942 BindingDB Entry DOI: 10.7270/Q2WD3ZGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase [110-330] (Flaveria bidentis (Coastal plain yellowtops)) | BDBM50257203 (CHEMBL449139 | sodium maleate) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.32E+4 | -5.54 | n/a | n/a | n/a | n/a | n/a | 8.3 | 20 |
Istituto di Biostrutture e Bioimmagini-CNR | Assay Description Inhibition constants of carboxylate inhibitors against F. bidentis CA I were determined by a stopped flow CO2 hydration assay at 20 °C. | J Enzyme Inhib Med Chem 29: 500-4 (2014) Article DOI: 10.3109/14756366.2013.813942 BindingDB Entry DOI: 10.7270/Q2WD3ZGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase [110-330] (Flaveria bidentis (Coastal plain yellowtops)) | BDBM50159794 (CHEMBL1357 | SODIUM LACTATE | Sodium; 2-hydroxy-pr...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 7.41E+4 | -5.54 | n/a | n/a | n/a | n/a | n/a | 8.3 | 20 |
Istituto di Biostrutture e Bioimmagini-CNR | Assay Description Inhibition constants of carboxylate inhibitors against F. bidentis CA I were determined by a stopped flow CO2 hydration assay at 20 °C. | J Enzyme Inhib Med Chem 29: 500-4 (2014) Article DOI: 10.3109/14756366.2013.813942 BindingDB Entry DOI: 10.7270/Q2WD3ZGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase [110-330] (Flaveria bidentis (Coastal plain yellowtops)) | BDBM36182 (CHEMBL509357 | pentanoate | valerate) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 7.75E+4 | -5.51 | n/a | n/a | n/a | n/a | n/a | 8.3 | 20 |
Istituto di Biostrutture e Bioimmagini-CNR | Assay Description Inhibition constants of carboxylate inhibitors against F. bidentis CA I were determined by a stopped flow CO2 hydration assay at 20 °C. | J Enzyme Inhib Med Chem 29: 500-4 (2014) Article DOI: 10.3109/14756366.2013.813942 BindingDB Entry DOI: 10.7270/Q2WD3ZGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase [110-330] (Flaveria bidentis (Coastal plain yellowtops)) | BDBM50079401 (CHEMBL62381 | Sodium butyrate | Sodium; butyrate |...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 8.23E+4 | -5.47 | n/a | n/a | n/a | n/a | n/a | 8.3 | 20 |
Istituto di Biostrutture e Bioimmagini-CNR | Assay Description Inhibition constants of carboxylate inhibitors against F. bidentis CA I were determined by a stopped flow CO2 hydration assay at 20 °C. | J Enzyme Inhib Med Chem 29: 500-4 (2014) Article DOI: 10.3109/14756366.2013.813942 BindingDB Entry DOI: 10.7270/Q2WD3ZGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase [110-330] (Flaveria bidentis (Coastal plain yellowtops)) | BDBM50257201 (CHEMBL500826 | sodium propionate) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 9.10E+4 | -5.42 | n/a | n/a | n/a | n/a | n/a | 8.3 | 20 |
Istituto di Biostrutture e Bioimmagini-CNR | Assay Description Inhibition constants of carboxylate inhibitors against F. bidentis CA I were determined by a stopped flow CO2 hydration assay at 20 °C. | J Enzyme Inhib Med Chem 29: 500-4 (2014) Article DOI: 10.3109/14756366.2013.813942 BindingDB Entry DOI: 10.7270/Q2WD3ZGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase [110-330] (Flaveria bidentis (Coastal plain yellowtops)) | BDBM50159798 (CHEMBL182856 | Sodium; L-Malate) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 9.25E+4 | -5.41 | n/a | n/a | n/a | n/a | n/a | 8.3 | 20 |
Istituto di Biostrutture e Bioimmagini-CNR | Assay Description Inhibition constants of carboxylate inhibitors against F. bidentis CA I were determined by a stopped flow CO2 hydration assay at 20 °C. | J Enzyme Inhib Med Chem 29: 500-4 (2014) Article DOI: 10.3109/14756366.2013.813942 BindingDB Entry DOI: 10.7270/Q2WD3ZGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase [110-330] (Flaveria bidentis (Coastal plain yellowtops)) | BDBM92964 (CHEMBL182928 | Oxalate) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | Article PubMed | 9.30E+4 | -5.40 | n/a | n/a | n/a | n/a | n/a | 8.3 | 20 |
Istituto di Biostrutture e Bioimmagini-CNR | Assay Description Inhibition constants of carboxylate inhibitors against F. bidentis CA I were determined by a stopped flow CO2 hydration assay at 20 °C. | J Enzyme Inhib Med Chem 29: 500-4 (2014) Article DOI: 10.3109/14756366.2013.813942 BindingDB Entry DOI: 10.7270/Q2WD3ZGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase [110-330] (Flaveria bidentis (Coastal plain yellowtops)) | BDBM50159793 (CHEMBL1354 | Natriumazetat | SODIUM ACETATE ANHYDR...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 9.51E+4 | -5.39 | n/a | n/a | n/a | n/a | n/a | 8.3 | 20 |
Istituto di Biostrutture e Bioimmagini-CNR | Assay Description Inhibition constants of carboxylate inhibitors against F. bidentis CA I were determined by a stopped flow CO2 hydration assay at 20 °C. | J Enzyme Inhib Med Chem 29: 500-4 (2014) Article DOI: 10.3109/14756366.2013.813942 BindingDB Entry DOI: 10.7270/Q2WD3ZGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase [110-330] (Flaveria bidentis (Coastal plain yellowtops)) | BDBM50155538 (CHEMBL183491 | Sodium; formate | sodium formate) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 9.75E+4 | -5.38 | n/a | n/a | n/a | n/a | n/a | 8.3 | 20 |
Istituto di Biostrutture e Bioimmagini-CNR | Assay Description Inhibition constants of carboxylate inhibitors against F. bidentis CA I were determined by a stopped flow CO2 hydration assay at 20 °C. | J Enzyme Inhib Med Chem 29: 500-4 (2014) Article DOI: 10.3109/14756366.2013.813942 BindingDB Entry DOI: 10.7270/Q2WD3ZGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase [110-330] (Flaveria bidentis (Coastal plain yellowtops)) | BDBM50159797 (CHEMBL359504 | Sodium; Malonate | sodium malonate) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | 1.00E+5 | -5.36 | n/a | n/a | n/a | n/a | n/a | 8.3 | 20 |
Istituto di Biostrutture e Bioimmagini-CNR | Assay Description Inhibition constants of carboxylate inhibitors against F. bidentis CA I were determined by a stopped flow CO2 hydration assay at 20 °C. | J Enzyme Inhib Med Chem 29: 500-4 (2014) Article DOI: 10.3109/14756366.2013.813942 BindingDB Entry DOI: 10.7270/Q2WD3ZGT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase [110-330] (Flaveria bidentis (Coastal plain yellowtops)) | BDBM50159792 (CHEMBL181886 | Natriumpyruvat | Pyruvate | pyruvic...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+7 | >-2.68 | n/a | n/a | n/a | n/a | n/a | 8.3 | 20 |
Istituto di Biostrutture e Bioimmagini-CNR | Assay Description Inhibition constants of carboxylate inhibitors against F. bidentis CA I were determined by a stopped flow CO2 hydration assay at 20 °C. | J Enzyme Inhib Med Chem 29: 500-4 (2014) Article DOI: 10.3109/14756366.2013.813942 BindingDB Entry DOI: 10.7270/Q2WD3ZGT | |||||||||||
More data for this Ligand-Target Pair |