Compile Data Set for Download or QSAR

Found 122 hits of ic50 for UniProtKB: P29473   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50138977 (CHEMBL419740 | N-(3-Aminomethyl-phenyl)-acetamidin...) Show SMILES CC(=N)Nc1cccc(CN)c1 Show InChI InChI=1S/C9H13N3/c1-7(11)12-9-4-2-3-8(5-9)6-10/h2-5H,6,10H2,1H3,(H2,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against endothelial nitric oxide synthase (eNOS)				J Med Chem 47: 703-10 (2004) Article DOI: 10.1021/jm030297m BindingDB Entry DOI: 10.7270/Q2MC90SQ
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50030171 (5-{[amino(hydrazino)methyl]amino}-2-ammoniopentano...) Show SMILES NNC(N)NCCCC([NH3+])C([O-])=O Show InChI InChI=1S/C6H17N5O2/c7-4(5(12)13)2-1-3-10-6(8)11-9/h4,6,10-11H,1-3,7-9H2,(H,12,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Compound was tested for its inhibitory activity against endothelial NO2- synthesis				J Med Chem 37: 1899-907 (1994) BindingDB Entry DOI: 10.7270/Q2VQ3391
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50225106 ((2S)-2-amino-5-{[(E)-amino(nitroimino)methyl]amino...) Show SMILES N[C@@H](CCCNC(N)=N[N+]([O-])=O)C(O)=O |r,w:8.8| Show InChI InChI=1S/C6H13N5O4/c7-4(5(12)13)2-1-3-9-6(8)10-11(14)15/h4H,1-3,7H2,(H,12,13)(H3,8,9,10)/t4-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity of conversion of radiolabeled arginine to citrulline by isomeric form of nitric oxide synthase Endothelial nitric oxide synthase ...				J Med Chem 41: 2636-42 (1998) Article DOI: 10.1021/jm980073h BindingDB Entry DOI: 10.7270/Q26Q1WD7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50270528 (3-BROMO-7-NITROINDAZOLE | 3-bromo-7-nitro-1H-indaz...) Show SMILES [O-][N+](=O)c1cccc2c(Br)n[nH]c12 Show InChI InChI=1S/C7H4BrN3O2/c8-7-4-2-1-3-5(11(12)13)6(4)9-10-7/h1-3H,(H,9,10)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université de Versailles Curated by ChEMBL					Assay Description Inhibition of bovine recombinant eNOS				Bioorg Med Chem 16: 5962-73 (2008) Article DOI: 10.1016/j.bmc.2008.04.056 BindingDB Entry DOI: 10.7270/Q2GB23VM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50122305 (CHEMBL552629 | N-(3-{[3-(3,5-Di-tert-butyl-4-hydro...) Show SMILES CC(C)(C)c1cc(CCCNCc2cccc(c2)N=C(N)c2cccs2)cc(c1O)C(C)(C)C |w:18.18| Show InChI InChI=1S/C29H39N3OS/c1-28(2,3)23-17-20(18-24(26(23)33)29(4,5)6)11-8-14-31-19-21-10-7-12-22(16-21)32-27(30)25-13-9-15-34-25/h7,9-10,12-13,15-18,31,33H,8,11,14,19H2,1-6H3,(H2,30,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut Henri Beaufour Curated by ChEMBL					Assay Description Inhibitory concentration tested against bovine endothelial nitric oxide synthase (eNOS)				Bioorg Med Chem Lett 13: 209-12 (2002) BindingDB Entry DOI: 10.7270/Q2K9382B
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50065362 ((S)-2-Amino-5-(5-methyl-2-nitro-phenylamino)-penta...) Show SMILES Cc1ccc(c(NCCC[C@H](N)C(O)=O)c1)[N+]([O-])=O Show InChI InChI=1S/C12H17N3O4/c1-8-4-5-11(15(18)19)10(7-8)14-6-2-3-9(13)12(16)17/h4-5,7,9,14H,2-3,6,13H2,1H3,(H,16,17)/t9-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity of conversion of radiolabeled arginine to citrulline by isomeric form of nitric oxide synthase Endothelial nitric oxide synthase ...				J Med Chem 41: 2636-42 (1998) Article DOI: 10.1021/jm980073h BindingDB Entry DOI: 10.7270/Q26Q1WD7
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50230993 ((2S)-2-amino-5-[(N-methylcarbamimidoyl)amino]penta...) Show SMILES CNC(N)=NCCC[C@H](N)C(O)=O |r,w:4.4| Show InChI InChI=1S/C7H16N4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11)/t5-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity of conversion of radiolabeled arginine to citrulline by isomeric form of nitric oxide synthase Endothelial nitric oxide synthase ...				J Med Chem 41: 2636-42 (1998) Article DOI: 10.1021/jm980073h BindingDB Entry DOI: 10.7270/Q26Q1WD7
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM196649 (US9212144, 4) Show SMILES Clc1cccc(CNCCc2ccc(NC(=N)c3cccs3)cc2)c1 Show InChI InChI=1S/C20H20ClN3S/c21-17-4-1-3-16(13-17)14-23-11-10-15-6-8-18(9-7-15)24-20(22)19-5-2-12-25-19/h1-9,12-13,23H,10-11,14H2,(H2,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	DrugBank MCE PC cid PC sid PDB UniChem	PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut Henri Beaufour Curated by ChEMBL					Assay Description Inhibitory concentration tested against bovine endothelial nitric oxide synthase (eNOS)				Bioorg Med Chem Lett 13: 209-12 (2002) BindingDB Entry DOI: 10.7270/Q2K9382B
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50122300 (CHEMBL541300 | N-(3-{[3-(4-Hydroxy-3,5-diisopropyl...) Show SMILES CC(C)c1cc(CCCNCc2cccc(c2)N=C(N)c2cccs2)cc(C(C)C)c1O |w:17.17| Show InChI InChI=1S/C27H35N3OS/c1-18(2)23-15-20(16-24(19(3)4)26(23)31)9-6-12-29-17-21-8-5-10-22(14-21)30-27(28)25-11-7-13-32-25/h5,7-8,10-11,13-16,18-19,29,31H,6,9,12,17H2,1-4H3,(H2,28,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institut Henri Beaufour Curated by ChEMBL					Assay Description Inhibitory concentration tested against bovine endothelial nitric oxide synthase (eNOS)				Bioorg Med Chem Lett 13: 209-12 (2002) BindingDB Entry DOI: 10.7270/Q2K9382B
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50065359 ((S)-2-Amino-5-(5-methyl-2-nitro-phenylsulfanyl)-pe...) Show SMILES Cc1ccc(c(SCCC[C@H](N)C(O)=O)c1)[N+]([O-])=O Show InChI InChI=1S/C12H16N2O4S/c1-8-4-5-10(14(17)18)11(7-8)19-6-2-3-9(13)12(15)16/h4-5,7,9H,2-3,6,13H2,1H3,(H,15,16)/t9-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity of conversion of radiolabeled arginine to citrulline by isomeric form of nitric oxide synthase Endothelial nitric oxide synthase ...				J Med Chem 41: 2636-42 (1998) Article DOI: 10.1021/jm980073h BindingDB Entry DOI: 10.7270/Q26Q1WD7
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50403464 (CHEMBL4166234) Show SMILES Cl.Cl.CC(=N)NCc1cccc(CNC(=O)[C@@H](N)CCC(O)=O)c1 |r| Show InChI InChI=1S/C25H35N5O5/c1-16(2)13-20(29-25(35)30-11-5-6-12-30)24(34)28-21(23(33)26-10-9-22(31)32)14-17-15-27-19-8-4-3-7-18(17)19/h3-4,7-8,15-16,20-21,27H,5-6,9-14H2,1-2H3,(H,26,33)(H,28,34)(H,29,35)(H,31,32)/t20-,21+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Chieti "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of recombinant bovine eNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in...				Eur J Med Chem 152: 53-64 (2018) Article DOI: 10.1016/j.ejmech.2018.04.027 BindingDB Entry DOI: 10.7270/Q2C2500M
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50065364 ((S)-2-Amino-5-(5-methyl-2-nitro-phenoxy)-pentanoic...) Show SMILES Cc1ccc(c(OCCC[C@H](N)C(O)=O)c1)[N+]([O-])=O Show InChI InChI=1S/C12H16N2O5/c1-8-4-5-10(14(17)18)11(7-8)19-6-2-3-9(13)12(15)16/h4-5,7,9H,2-3,6,13H2,1H3,(H,15,16)/t9-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity of conversion of radiolabeled arginine to citrulline by isomeric form of nitric oxide synthase Endothelial nitric oxide synthase ...				J Med Chem 41: 2636-42 (1998) Article DOI: 10.1021/jm980073h BindingDB Entry DOI: 10.7270/Q26Q1WD7
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50295571 (3-[4'-(4''-Chlorobenzyloxy)benzoyl]-3,4-dihydro-8-...) Show SMILES Cc1ccn2CC(CN[c+]2c1)C(=O)c1ccc(OCc2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C23H21ClN2O2/c1-16-10-11-26-14-19(13-25-22(26)12-16)23(27)18-4-8-21(9-5-18)28-15-17-2-6-20(24)7-3-17/h2-12,19H,13-15H2,1H3/p+1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as conversion of [gamma-14C]L-arginine to [14C]L-citrulline by radioacti...				Eur J Med Chem 44: 2877-87 (2009) Article DOI: 10.1016/j.ejmech.2008.12.007 BindingDB Entry DOI: 10.7270/Q2KD1ZV6
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50295566 (3-[4'-(4''-Cyanophenyl)benzoyl]-3,4-dihydro-8-meth...) Show SMILES Cc1ccn2CC(CN[c+]2c1)C(=O)c1ccc(cc1)-c1ccc(cc1)C#N Show InChI InChI=1S/C23H19N3O/c1-16-10-11-26-15-21(14-25-22(26)12-16)23(27)20-8-6-19(7-9-20)18-4-2-17(13-24)3-5-18/h2-12,21H,14-15H2,1H3/p+1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as conversion of [gamma-14C]L-arginine to [14C]L-citrulline by radioacti...				Eur J Med Chem 44: 2877-87 (2009) Article DOI: 10.1016/j.ejmech.2008.12.007 BindingDB Entry DOI: 10.7270/Q2KD1ZV6
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50270530 (3-Bromo-1H-indazole-7-carbonitrile | CHEMBL451541) Show SMILES Brc1n[nH]c2c(cccc12)C#N Show InChI InChI=1S/C8H4BrN3/c9-8-6-3-1-2-5(4-10)7(6)11-12-8/h1-3H,(H,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université de Versailles Curated by ChEMBL					Assay Description Inhibition of bovine recombinant eNOS				Bioorg Med Chem 16: 5962-73 (2008) Article DOI: 10.1016/j.bmc.2008.04.056 BindingDB Entry DOI: 10.7270/Q2GB23VM
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50113348 (5-[1,2]Dithiolan-3-yl-pentanoic acid | CHEMBL33240...) Show SMILES NC(=Nc1ccccc1)c1cccs1 |w:2.2| Show InChI InChI=1S/C11H10N2S/c12-11(10-7-4-8-14-10)13-9-5-2-1-3-6-9/h1-8H,(H2,12,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institut Henri Beaufour Curated by ChEMBL					Assay Description Inhibitory concentration tested against bovine endothelial nitric oxide synthase (eNOS)				Bioorg Med Chem Lett 13: 209-12 (2002) BindingDB Entry DOI: 10.7270/Q2K9382B
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50122302 (CHEMBL66682 | N-(3-{[2-(3,5-Di-tert-butyl-4-hydrox...) Show SMILES CC(C)(C)c1cc(CCNCc2cccc(c2)N=C(N)c2cccs2)cc(c1O)C(C)(C)C |w:17.17| Show InChI InChI=1S/C28H37N3OS/c1-27(2,3)22-16-19(17-23(25(22)32)28(4,5)6)12-13-30-18-20-9-7-10-21(15-20)31-26(29)24-11-8-14-33-24/h7-11,14-17,30,32H,12-13,18H2,1-6H3,(H2,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institut Henri Beaufour Curated by ChEMBL					Assay Description Inhibitory concentration tested against bovine endothelial nitric oxide synthase (eNOS)				Bioorg Med Chem Lett 13: 209-12 (2002) BindingDB Entry DOI: 10.7270/Q2K9382B
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50122306 (CHEMBL559220 | N-{3-[(3,5-Di-tert-butyl-4-hydroxy-...) Show SMILES CC(C)(C)c1cc(CNCc2cccc(c2)N=C(N)c2cccs2)cc(c1O)C(C)(C)C |w:16.16| Show InChI InChI=1S/C27H35N3OS/c1-26(2,3)21-14-19(15-22(24(21)31)27(4,5)6)17-29-16-18-9-7-10-20(13-18)30-25(28)23-11-8-12-32-23/h7-15,29,31H,16-17H2,1-6H3,(H2,28,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institut Henri Beaufour Curated by ChEMBL					Assay Description Inhibitory concentration tested against bovine endothelial nitric oxide synthase (eNOS)				Bioorg Med Chem Lett 13: 209-12 (2002) BindingDB Entry DOI: 10.7270/Q2K9382B
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50065369 (CHEMBL89454 | N*1*-(5-Methyl-2-nitro-phenyl)-butan...) Show SMILES Cc1ccc(c(NCCCCN)c1)[N+]([O-])=O Show InChI InChI=1S/C11H17N3O2/c1-9-4-5-11(14(15)16)10(8-9)13-7-3-2-6-12/h4-5,8,13H,2-3,6-7,12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity of conversion of radiolabeled arginine to citrulline by isomeric form of nitric oxide synthase Endothelial nitric oxide synthase ...				J Med Chem 41: 2636-42 (1998) Article DOI: 10.1021/jm980073h BindingDB Entry DOI: 10.7270/Q26Q1WD7
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50065843 (CHEMBL553081 | CHEMBL555715 | N-(3-Aminomethyl-phe...) Show SMILES NCc1cccc(c1)N=C(N)c1cccs1 |w:8.8| Show InChI InChI=1S/C12H13N3S/c13-8-9-3-1-4-10(7-9)15-12(14)11-5-2-6-16-11/h1-7H,8,13H2,(H2,14,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institut Henri Beaufour Curated by ChEMBL					Assay Description Inhibitory concentration tested against bovine endothelial nitric oxide synthase (eNOS)				Bioorg Med Chem Lett 13: 209-12 (2002) BindingDB Entry DOI: 10.7270/Q2K9382B
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50122299 (CHEMBL538500 | N-[4-(2-Amino-ethyl)-phenyl]-thioph...) Show SMILES NCCc1ccc(cc1)N=C(N)c1cccs1 |w:9.9| Show InChI InChI=1S/C13H15N3S/c14-8-7-10-3-5-11(6-4-10)16-13(15)12-2-1-9-17-12/h1-6,9H,7-8,14H2,(H2,15,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institut Henri Beaufour Curated by ChEMBL					Assay Description Inhibitory concentration tested against bovine endothelial nitric oxide synthase (eNOS)				Bioorg Med Chem Lett 13: 209-12 (2002) BindingDB Entry DOI: 10.7270/Q2K9382B
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50095303 (CHEMBL3589092) Show SMILES CC(=N)NCc1cccc(CNCc2ccccc2[N+]([O-])=O)c1 Show InChI InChI=1S/C17H20N4O2/c1-13(18)20-11-15-6-4-5-14(9-15)10-19-12-16-7-2-3-8-17(16)21(22)23/h2-9,19H,10-12H2,1H3,(H2,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Chieti"G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of bovine recombinant eNOS using [3H]L-arginine substrate assessed as formation of [3H]L-citruline by liquid scintillation counting analys...				ACS Med Chem Lett 6: 635-40 (2015) Article DOI: 10.1021/acsmedchemlett.5b00149 BindingDB Entry DOI: 10.7270/Q2C53NKC
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50271277 (1H-Indazole-7-carbonitrile | CHEMBL484298) Show SMILES N#Cc1cccc2cn[nH]c12 Show InChI InChI=1S/C8H5N3/c9-4-6-2-1-3-7-5-10-11-8(6)7/h1-3,5H,(H,10,11)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université de Versailles Curated by ChEMBL					Assay Description Inhibition of bovine recombinant eNOS				Bioorg Med Chem 16: 5962-73 (2008) Article DOI: 10.1016/j.bmc.2008.04.056 BindingDB Entry DOI: 10.7270/Q2GB23VM
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50209245 (CHEMBL247378) Show SMILES [O-][N+](=O)c1cccc2cn[nH]c12 Show InChI InChI=1S/C7H5N3O2/c11-10(12)6-3-1-2-5-4-8-9-7(5)6/h1-4H,(H,8,9)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université de Versailles Curated by ChEMBL					Assay Description Inhibition of bovine recombinant eNOS				Bioorg Med Chem 16: 5962-73 (2008) Article DOI: 10.1016/j.bmc.2008.04.056 BindingDB Entry DOI: 10.7270/Q2GB23VM
					More data for this Ligand-Target Pair				3D Structure (crystal)
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50122301 (CHEMBL542633 | N-(4-Aminomethyl-phenyl)-thiophene-...) Show SMILES NCc1ccc(cc1)N=C(N)c1cccs1 |w:8.8| Show InChI InChI=1S/C12H13N3S/c13-8-9-3-5-10(6-4-9)15-12(14)11-2-1-7-16-11/h1-7H,8,13H2,(H2,14,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institut Henri Beaufour Curated by ChEMBL					Assay Description Inhibitory concentration tested against bovine endothelial nitric oxide synthase (eNOS)				Bioorg Med Chem Lett 13: 209-12 (2002) BindingDB Entry DOI: 10.7270/Q2K9382B
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50065366 ((S)-2-Amino-5-(5-methyl-2-nitro-phenylamino)-penta...) Show SMILES Cc1ccc(c(NCCC[C@H](N)CO)c1)[N+]([O-])=O Show InChI InChI=1S/C12H19N3O3/c1-9-4-5-12(15(17)18)11(7-9)14-6-2-3-10(13)8-16/h4-5,7,10,14,16H,2-3,6,8,13H2,1H3/t10-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity of conversion of radiolabeled arginine to citrulline by isomeric form of nitric oxide synthase Endothelial nitric oxide synthase ...				J Med Chem 41: 2636-42 (1998) Article DOI: 10.1021/jm980073h BindingDB Entry DOI: 10.7270/Q26Q1WD7
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50209245 (CHEMBL247378) Show SMILES [O-][N+](=O)c1cccc2cn[nH]c12 Show InChI InChI=1S/C7H5N3O2/c11-10(12)6-3-1-2-5-4-8-9-7(5)6/h1-4H,(H,8,9)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as conversion of [gamma-14C]L-arginine to [14C]L-citrulline by radioacti...				Eur J Med Chem 44: 2877-87 (2009) Article DOI: 10.1016/j.ejmech.2008.12.007 BindingDB Entry DOI: 10.7270/Q2KD1ZV6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50295570 (3,4-Dihydro-6,8-dimethyl-3-[2-(6-methylnaphthoyl)]...) Show SMILES Cc1cc(C)n2CC(CN[c+]2c1)C(=O)c1ccc2cc(C)ccc2c1 Show InChI InChI=1S/C22H22N2O/c1-14-4-5-18-11-19(7-6-17(18)9-14)22(25)20-12-23-21-10-15(2)8-16(3)24(21)13-20/h4-11,20H,12-13H2,1-3H3/p+1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as conversion of [gamma-14C]L-arginine to [14C]L-citrulline by radioacti...				Eur J Med Chem 44: 2877-87 (2009) Article DOI: 10.1016/j.ejmech.2008.12.007 BindingDB Entry DOI: 10.7270/Q2KD1ZV6
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50065375 ((S)-2-Amino-5-(2,6-dinitro-phenylamino)-pentanoic ...) Show SMILES N[C@@H](CCCNc1c(cccc1[N+]([O-])=O)[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C11H14N4O6/c12-7(11(16)17)3-2-6-13-10-8(14(18)19)4-1-5-9(10)15(20)21/h1,4-5,7,13H,2-3,6,12H2,(H,16,17)/t7-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity of conversion of radiolabeled arginine to citrulline by isomeric form of nitric oxide synthase Endothelial nitric oxide synthase ...				J Med Chem 41: 2636-42 (1998) Article DOI: 10.1021/jm980073h BindingDB Entry DOI: 10.7270/Q26Q1WD7
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50295567 (3-[4'-(4''-Methoxyphenyl)benzoyl]-3,4-dihydro-8-me...) Show SMILES COc1ccc(cc1)-c1ccc(cc1)C(=O)C1CN[c+]2cc(C)ccn2C1 Show InChI InChI=1S/C23H22N2O2/c1-16-11-12-25-15-20(14-24-22(25)13-16)23(26)19-5-3-17(4-6-19)18-7-9-21(27-2)10-8-18/h3-13,20H,14-15H2,1-2H3/p+1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Christian-Albrechts-University of Kiel Curated by ChEMBL					Assay Description Inhibition of bovine recombinant eNOS expressed in Escherichia coli assessed as conversion of [gamma-14C]L-arginine to [14C]L-citrulline by radioacti...				Eur J Med Chem 44: 2877-87 (2009) Article DOI: 10.1016/j.ejmech.2008.12.007 BindingDB Entry DOI: 10.7270/Q2KD1ZV6
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50292746 ((+/-)-N-(1-Phenylpropyl)ethanimidamide hydrobromid...) Show SMILES CCC(N=C(C)N)c1ccccc1 |w:3.2| Show InChI InChI=1S/C11H16N2/c1-3-11(13-9(2)12)10-7-5-4-6-8-10/h4-8,11H,3H2,1-2H3,(H2,12,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università G. d'Annunzio Curated by ChEMBL					Assay Description Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobin				Bioorg Med Chem Lett 20: 6495-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.059 BindingDB Entry DOI: 10.7270/Q2GX4BTP
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50330055 ((+/-)-2-Methyl-1-(1-phenylethyl)-1H-imidazole | CH...) Show SMILES CC(c1ccccc1)n1ccnc1C Show InChI InChI=1S/C12H14N2/c1-10(12-6-4-3-5-7-12)14-9-8-13-11(14)2/h3-10H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università G. d'Annunzio Curated by ChEMBL					Assay Description Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobin				Bioorg Med Chem Lett 20: 6495-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.059 BindingDB Entry DOI: 10.7270/Q2GX4BTP
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM7885 (1-benzyl-2-methyl-1H-imidazole | US9138393, 1-benz...) Show SMILES Cc1nccn1Cc1ccccc1 Show InChI InChI=1S/C11H12N2/c1-10-12-7-8-13(10)9-11-5-3-2-4-6-11/h2-8H,9H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università G. d'Annunzio Curated by ChEMBL					Assay Description Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobin				Bioorg Med Chem Lett 20: 6495-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.059 BindingDB Entry DOI: 10.7270/Q2GX4BTP
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50095302 (CHEMBL3589091) Show SMILES CC(=N)NCc1cccc(CNC(=O)c2ccc(cc2)C(O)=O)c1 Show InChI InChI=1S/C18H19N3O3/c1-12(19)20-10-13-3-2-4-14(9-13)11-21-17(22)15-5-7-16(8-6-15)18(23)24/h2-9H,10-11H2,1H3,(H2,19,20)(H,21,22)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Chieti"G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of bovine recombinant eNOS using [3H]L-arginine substrate assessed as formation of [3H]L-citruline by liquid scintillation counting analys...				ACS Med Chem Lett 6: 635-40 (2015) Article DOI: 10.1021/acsmedchemlett.5b00149 BindingDB Entry DOI: 10.7270/Q2C53NKC
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50370372 (CHEMBL1169428) Show SMILES N[C@@H]1CN[C@H](C1)C(=O)N[C@H](CCCN=C(N)N[N+]([O-])=O)C(N)=O |r,w:13.13| Show InChI InChI=1S/C11H22N8O4/c12-6-4-8(16-5-6)10(21)17-7(9(13)20)2-1-3-15-11(14)18-19(22)23/h6-8,16H,1-5,12H2,(H2,13,20)(H,17,21)(H3,14,15,18)/t6-,7+,8+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against endothelial nitric oxide synthase (eNOS)				J Med Chem 47: 703-10 (2004) Article DOI: 10.1021/jm030297m BindingDB Entry DOI: 10.7270/Q2MC90SQ
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50370373 (CHEMBL1169426) Show SMILES N[C@@H](CCCN=C(N)N[N+]([O-])=O)C(=O)N1C[C@H](N)C[C@@H]1C(N)=O |r,w:5.4| Show InChI InChI=1S/C11H22N8O4/c12-6-4-8(9(14)20)18(5-6)10(21)7(13)2-1-3-16-11(15)17-19(22)23/h6-8H,1-5,12-13H2,(H2,14,20)(H3,15,16,17)/t6-,7+,8-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against endothelial nitric oxide synthase (eNOS)				J Med Chem 47: 703-10 (2004) Article DOI: 10.1021/jm030297m BindingDB Entry DOI: 10.7270/Q2MC90SQ
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50138980 ((2S,4R)-N-((1S)-1-(aminocarbonyl)-4-{[(E)-imino(ni...) Show SMILES NC(=O)[C@H](CCCNC(=N)N[N+]([O-])=O)NC(=O)C1C[C@H](CN1)N=[N+]=[N-] Show InChI InChI=1S/C11H20N10O4/c12-9(22)7(2-1-3-15-11(13)19-21(24)25)17-10(23)8-4-6(5-16-8)18-20-14/h6-8,16H,1-5H2,(H2,12,22)(H,17,23)(H3,13,15,19)/t6-,7+,8?/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against endothelial nitric oxide synthase (eNOS)				J Med Chem 47: 703-10 (2004) Article DOI: 10.1021/jm030297m BindingDB Entry DOI: 10.7270/Q2MC90SQ
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50138975 ((2S,4S)-1-((2S)-2-amino-5-{[(E)-imino(nitroamino)m...) Show SMILES N[C@@H](CCCNC(=N)N[N+]([O-])=O)C(=O)N1C[C@H](C[C@H]1C(N)=O)NC(=O)C(F)(F)F Show InChI InChI=1S/C13H21F3N8O5/c14-13(15,16)11(27)21-6-4-8(9(18)25)23(5-6)10(26)7(17)2-1-3-20-12(19)22-24(28)29/h6-8H,1-5,17H2,(H2,18,25)(H,21,27)(H3,19,20,22)/t6-,7-,8-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against endothelial nitric oxide synthase (eNOS)				J Med Chem 47: 703-10 (2004) Article DOI: 10.1021/jm030297m BindingDB Entry DOI: 10.7270/Q2MC90SQ
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50138987 ((2S,4S)-N-((1R)-1-(aminocarbonyl)-4-{[(E)-imino(ni...) Show SMILES NC(=O)[C@@H](CCCNC(=N)N[N+]([O-])=O)NC(=O)C1C[C@@H](CN1)N=[N+]=[N-] Show InChI InChI=1S/C11H20N10O4/c12-9(22)7(2-1-3-15-11(13)19-21(24)25)17-10(23)8-4-6(5-16-8)18-20-14/h6-8,16H,1-5H2,(H2,12,22)(H,17,23)(H3,13,15,19)/t6-,7+,8?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against endothelial nitric oxide synthase (eNOS)				J Med Chem 47: 703-10 (2004) Article DOI: 10.1021/jm030297m BindingDB Entry DOI: 10.7270/Q2MC90SQ
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50370374 (CHEMBL1169424) Show SMILES NC(=O)[C@@H](CCCN=C(N)N[N+]([O-])=O)NC(=O)[C@H]1C[C@@H](CN1)N=[N+]=[N-] |r,w:7.6| Show InChI InChI=1S/C11H20N10O4/c12-9(22)7(2-1-3-15-11(13)19-21(24)25)17-10(23)8-4-6(5-16-8)18-20-14/h6-8,16H,1-5H2,(H2,12,22)(H,17,23)(H3,13,15,19)/t6-,7+,8+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against endothelial nitric oxide synthase (eNOS)				J Med Chem 47: 703-10 (2004) Article DOI: 10.1021/jm030297m BindingDB Entry DOI: 10.7270/Q2MC90SQ
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50065358 ((S)-2-Amino-5-(4-fluoro-2-nitro-phenylamino)-penta...) Show SMILES N[C@@H](CCCNc1ccc(F)cc1[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C11H14FN3O4/c12-7-3-4-9(10(6-7)15(18)19)14-5-1-2-8(13)11(16)17/h3-4,6,8,14H,1-2,5,13H2,(H,16,17)/t8-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity of conversion of radiolabeled arginine to citrulline by isomeric form of nitric oxide synthase Endothelial nitric oxide synthase ...				J Med Chem 41: 2636-42 (1998) Article DOI: 10.1021/jm980073h BindingDB Entry DOI: 10.7270/Q26Q1WD7
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50065367 ((S)-2-Amino-5-(2-nitro-phenylamino)-pentanoic acid...) Show SMILES N[C@@H](CCCNc1ccccc1[N+]([O-])=O)C(O)=O Show InChI InChI=1S/C11H15N3O4/c12-8(11(15)16)4-3-7-13-9-5-1-2-6-10(9)14(17)18/h1-2,5-6,8,13H,3-4,7,12H2,(H,15,16)/t8-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibitory activity of conversion of radiolabeled arginine to citrulline by isomeric form of nitric oxide synthase Endothelial nitric oxide synthase ...				J Med Chem 41: 2636-42 (1998) Article DOI: 10.1021/jm980073h BindingDB Entry DOI: 10.7270/Q26Q1WD7
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50095304 (CHEMBL3589093) Show SMILES CC(=N)NCc1cccc(CN(Cc2ccc(cc2)[N+]([O-])=O)Cc2ccc(cc2)[N+]([O-])=O)c1 Show InChI InChI=1S/C24H25N5O4/c1-18(25)26-14-21-3-2-4-22(13-21)17-27(15-19-5-9-23(10-6-19)28(30)31)16-20-7-11-24(12-8-20)29(32)33/h2-13H,14-17H2,1H3,(H2,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Chieti"G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of bovine recombinant eNOS using [3H]L-arginine substrate assessed as formation of [3H]L-citruline by liquid scintillation counting analys...				ACS Med Chem Lett 6: 635-40 (2015) Article DOI: 10.1021/acsmedchemlett.5b00149 BindingDB Entry DOI: 10.7270/Q2C53NKC
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50330054 (4-[(2-Methyl-1H-imidazol-1-yl)methyl]pyridine | CH...) Show SMILES Cc1nccn1Cc1ccncc1 Show InChI InChI=1S/C10H11N3/c1-9-12-6-7-13(9)8-10-2-4-11-5-3-10/h2-7H,8H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università G. d'Annunzio Curated by ChEMBL					Assay Description Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobin				Bioorg Med Chem Lett 20: 6495-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.059 BindingDB Entry DOI: 10.7270/Q2GX4BTP
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50330057 (1-[(3-Methoxybenzyl)amino]ethaniminium chloride | ...) Show SMILES COc1cccc(CN=C(C)N)c1 |w:8.7| Show InChI InChI=1S/C10H14N2O/c1-8(11)12-7-9-4-3-5-10(6-9)13-2/h3-6H,7H2,1-2H3,(H2,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università G. d'Annunzio Curated by ChEMBL					Assay Description Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobin				Bioorg Med Chem Lett 20: 6495-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.059 BindingDB Entry DOI: 10.7270/Q2GX4BTP
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50330059 ((+/-)-1-[(2-Methyl-1-phenylpropyl)amino]ethanimini...) Show SMILES CC(C)C(N=C(C)N)c1ccccc1 |w:4.3| Show InChI InChI=1S/C12H18N2/c1-9(2)12(14-10(3)13)11-7-5-4-6-8-11/h4-9,12H,1-3H3,(H2,13,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Università G. d'Annunzio Curated by ChEMBL					Assay Description Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobin				Bioorg Med Chem Lett 20: 6495-9 (2010) Article DOI: 10.1016/j.bmcl.2010.09.059 BindingDB Entry DOI: 10.7270/Q2GX4BTP
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50122304 (CHEMBL539004 | N-(4-Amino-phenyl)-thiophene-2-carb...) Show SMILES NC(=Nc1ccc(N)cc1)c1cccs1 |w:2.2| Show InChI InChI=1S/C11H11N3S/c12-8-3-5-9(6-4-8)14-11(13)10-2-1-7-15-10/h1-7H,12H2,(H2,13,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Institut Henri Beaufour Curated by ChEMBL					Assay Description Inhibitory concentration tested against bovine endothelial nitric oxide synthase (eNOS)				Bioorg Med Chem Lett 13: 209-12 (2002) BindingDB Entry DOI: 10.7270/Q2K9382B
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50098937 ((S)-methyl 2-amino-5-(amino(nitroamino)methyleneam...) Show SMILES COC(=O)[C@@H](N)CCCNC(N)=N[N+]([O-])=O |r,w:12.12| Show InChI InChI=1S/C7H15N5O4/c1-16-6(13)5(8)3-2-4-10-7(9)11-12(14)15/h5H,2-4,8H2,1H3,(H3,9,10,11)/t5-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Compound was tested for for its inhibitory activity against endothelial NO2- synthesis				J Med Chem 37: 1899-907 (1994) BindingDB Entry DOI: 10.7270/Q2VQ3391
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50138972 ((2S,4S)-N-((1S)-1-(aminocarbonyl)-4-{[(E)-imino(ni...) Show SMILES NC(=O)[C@H](CCCNC(=N)N[N+]([O-])=O)NC(=O)C1C[C@@H](CN1)N=[N+]=[N-] Show InChI InChI=1S/C11H20N10O4/c12-9(22)7(2-1-3-15-11(13)19-21(24)25)17-10(23)8-4-6(5-16-8)18-20-14/h6-8,16H,1-5H2,(H2,12,22)(H,17,23)(H3,13,15,19)/t6-,7-,8?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against endothelial nitric oxide synthase (eNOS)				J Med Chem 47: 703-10 (2004) Article DOI: 10.1021/jm030297m BindingDB Entry DOI: 10.7270/Q2MC90SQ
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bos taurus (bovine))	BDBM50370358 (CHEMBL1169434) Show SMILES N[C@H](CCCN=C(N)N[N+]([O-])=O)C(=O)N1C[C@@H](N)C[C@@H]1C(N)=O |r,w:5.4| Show InChI InChI=1S/C11H22N8O4/c12-6-4-8(9(14)20)18(5-6)10(21)7(13)2-1-3-16-11(15)17-19(22)23/h6-8H,1-5,12-13H2,(H2,14,20)(H3,15,16,17)/t6-,7+,8+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Northwestern University Curated by ChEMBL					Assay Description Inhibitory activity against endothelial nitric oxide synthase (eNOS)				J Med Chem 47: 703-10 (2004) Article DOI: 10.1021/jm030297m BindingDB Entry DOI: 10.7270/Q2MC90SQ
					More data for this Ligand-Target Pair

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