BindingDB PrimarySearch

Found 37 hits of ic50 for UniProtKB: P15374
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50590284 (CHEMBL5192316) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00218j BindingDB Entry DOI: 10.7270/Q27S7SQ9
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50590283 (CHEMBL5169766 \| US20230303547, Reference Example D) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1039/d1md00218j BindingDB Entry DOI: 10.7270/Q27S7SQ9
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50431630 (KRX-0401 \| PERIFOSINE) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113970 BindingDB Entry DOI: 10.7270/Q2BV7MNZ
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM53421 (4-Cyclohexyl-2-phenyl-quinazoline \| 4-cyclohexyl-2...) Show SMILES C1CCC(CC1)c1nc(nc2ccccc12)-c1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of UCHL3 in human H1299 cells				Nat Chem Biol 3: 697-705 (2007) Article DOI: 10.1038/nchembio.2007.43 BindingDB Entry DOI: 10.7270/Q2KW5G7P
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50594731 (CHEMBL1241028) Show SMILES Clc1c2C(=O)CC(=O)c2c(Cl)c(Cl)c1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113970 BindingDB Entry DOI: 10.7270/Q2BV7MNZ
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50069764 (CHEMBL3407501) Show SMILES Fc1ccc(cc1)-c1nc2c(o1)C(=O)c1ccccc1C2=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113970 BindingDB Entry DOI: 10.7270/Q2BV7MNZ
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50594730 (CHEMBL5193983) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113970 BindingDB Entry DOI: 10.7270/Q2BV7MNZ
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50594729 (CHEBI:27485 \| CHEMBL1397260) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113970 BindingDB Entry DOI: 10.7270/Q2BV7MNZ
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50538571 (CHEMBL4635160) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
RAPT Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human GST-tagged UCHL3 expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine1...				J Med Chem 63: 5398-5420 (2020) Article DOI: 10.1021/acs.jmedchem.0c00245 BindingDB Entry DOI: 10.7270/Q2XK8K2T
RAPT Therapeutics, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM65518 (5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	7.5	25
University of Delaware					Assay Description Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...				ACS Chem Biol 12: 2399-2407 (2017) Article DOI: 10.1021/acschembio.7b00543 BindingDB Entry DOI: 10.7270/Q21J97WD
University of Delaware					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50442907 (Acetyl Isogambogic Acid \| CHEMBL3039433) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.54E+4	n/a	n/a	n/a	n/a	7.5	25
University of Delaware					Assay Description Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...				ACS Chem Biol 12: 2399-2407 (2017) Article DOI: 10.1021/acschembio.7b00543 BindingDB Entry DOI: 10.7270/Q21J97WD
University of Delaware					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50326012 (3-(acetoxyimino)-5-bromo-1-(3,4-dichlorobenzyl)ind...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of UCHL3 in human H1299 cells				Nat Chem Biol 3: 697-705 (2007) Article DOI: 10.1038/nchembio.2007.43 BindingDB Entry DOI: 10.7270/Q2KW5G7P
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50326014 (3-(acetoxyimino)-1-(3,4-dichlorobenzyl)-5-iodoindo...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of UCHL3 in human H1299 cells				Nat Chem Biol 3: 697-705 (2007) Article DOI: 10.1038/nchembio.2007.43 BindingDB Entry DOI: 10.7270/Q2KW5G7P
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM200235 (Rifampicin \| cid_5381226) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.48E+4	n/a	n/a	n/a	n/a	7.5	25
University of Delaware					Assay Description Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...				ACS Chem Biol 12: 2399-2407 (2017) Article DOI: 10.1021/acschembio.7b00543 BindingDB Entry DOI: 10.7270/Q21J97WD
University of Delaware					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50594733 (CHEMBL4303698) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113970 BindingDB Entry DOI: 10.7270/Q2BV7MNZ
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50326013 (3-(acetoxyimino)-5-bromo-1-(2,5-dichlorobenzyl)ind...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of UCHL3 in human H1299 cells				Nat Chem Biol 3: 697-705 (2007) Article DOI: 10.1038/nchembio.2007.43 BindingDB Entry DOI: 10.7270/Q2KW5G7P
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM205457 ((2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	3.21E+4	n/a	n/a	n/a	n/a	7.5	25
University of Delaware					Assay Description Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...				ACS Chem Biol 12: 2399-2407 (2017) Article DOI: 10.1021/acschembio.7b00543 BindingDB Entry DOI: 10.7270/Q21J97WD
University of Delaware					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50326015 (5-(4-butylphenyl)-4-(4-isopropylphenyl)-4H-1,2,4-t...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of UCHL3 in human H1299 cells				Nat Chem Biol 3: 697-705 (2007) Article DOI: 10.1038/nchembio.2007.43 BindingDB Entry DOI: 10.7270/Q2KW5G7P
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50594732 (CHEMBL5195092) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113970 BindingDB Entry DOI: 10.7270/Q2BV7MNZ
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50242207 (CHEMBL455364 \| Mangiferin) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.26E+4	n/a	n/a	n/a	n/a	7.5	25
University of Delaware					Assay Description Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...				ACS Chem Biol 12: 2399-2407 (2017) Article DOI: 10.1021/acschembio.7b00543 BindingDB Entry DOI: 10.7270/Q21J97WD
University of Delaware					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM24778 (2-methyl-1,4-dihydronaphthalene-1,4-dione \| 2-meth...) Show SMILES CC1=CC(=O)c2ccccc2C1=O \|t:1\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of UCHL3 in human H1299 cells				Nat Chem Biol 3: 697-705 (2007) Article DOI: 10.1038/nchembio.2007.43 BindingDB Entry DOI: 10.7270/Q2KW5G7P
Institute for Biomedical Research Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM24778 (2-methyl-1,4-dihydronaphthalene-1,4-dione \| 2-meth...) Show SMILES CC1=CC(=O)c2ccccc2C1=O \|t:1\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	7.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113970 BindingDB Entry DOI: 10.7270/Q2BV7MNZ
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50552483 (CHEMBL4763594) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human UCHL3 assessed as reduction in cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine110-glycine using...				Citation and Details Article DOI: 10.1016/j.bmc.2020.115931 BindingDB Entry DOI: 10.7270/Q2R49VFD
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50538549 (CHEMBL4641424) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
RAPT Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human GST-tagged UCHL3 expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine1...				J Med Chem 63: 5398-5420 (2020) Article DOI: 10.1021/acs.jmedchem.0c00245 BindingDB Entry DOI: 10.7270/Q2XK8K2T
RAPT Therapeutics, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50270667 (CHEMBL4130194) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
RAPT Therapeutics, Inc. Curated by ChEMBL					Assay Description Inhibition of human GST-tagged UCHL3 expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine1...				J Med Chem 63: 5398-5420 (2020) Article DOI: 10.1021/acs.jmedchem.0c00245 BindingDB Entry DOI: 10.7270/Q2XK8K2T
RAPT Therapeutics, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM23421 (1-benzyl-3-hydroxy-4-[(5-methylfuran-2-yl)carbonyl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+5	n/a	n/a	n/a	n/a	7.8	22
Waseda University					Assay Description Enzyme reactions were carried out on Costar 96-well black assay plates. After the reaction, AMC fluorescence (excitation wavelength: 355 nm, emission...				Bioorg Med Chem 15: 6810-8 (2007) Article DOI: 10.1016/j.bmc.2007.07.016 BindingDB Entry DOI: 10.7270/Q2ZK5DZK
Waseda University					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50069762 (CHEMBL3182437 \| ML323 \| US9802904, 87) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.14E+5	n/a	n/a	n/a	n/a	7.5	25
University of Delaware					Assay Description Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...				ACS Chem Biol 12: 2399-2407 (2017) Article DOI: 10.1021/acschembio.7b00543 BindingDB Entry DOI: 10.7270/Q21J97WD
University of Delaware					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM65524 ((-)-Aricine \| Heterophylline (VAN) \| Quinovatine) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.14E+5	n/a	n/a	n/a	n/a	7.5	25
University of Delaware					Assay Description Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...				ACS Chem Biol 12: 2399-2407 (2017) Article DOI: 10.1021/acschembio.7b00543 BindingDB Entry DOI: 10.7270/Q21J97WD
University of Delaware					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM23427 (5-(4-fluorophenyl)-3-hydroxy-4-[(5-methylfuran-2-y...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.23E+5	n/a	n/a	n/a	n/a	7.8	22
Waseda University					Assay Description Enzyme reactions were carried out on Costar 96-well black assay plates. After the reaction, AMC fluorescence (excitation wavelength: 355 nm, emission...				Bioorg Med Chem 15: 6810-8 (2007) Article DOI: 10.1016/j.bmc.2007.07.016 BindingDB Entry DOI: 10.7270/Q2ZK5DZK
Waseda University					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM23426 (3-hydroxy-5-(4-methoxyphenyl)-1-(1,3,4-thiadiazol-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.54E+5	n/a	n/a	n/a	n/a	7.8	22
Waseda University					Assay Description Enzyme reactions were carried out on Costar 96-well black assay plates. After the reaction, AMC fluorescence (excitation wavelength: 355 nm, emission...				Bioorg Med Chem 15: 6810-8 (2007) Article DOI: 10.1016/j.bmc.2007.07.016 BindingDB Entry DOI: 10.7270/Q2ZK5DZK
Waseda University					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50271098 (CHEMBL4129140) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Progenra, Inc. Curated by ChEMBL					Assay Description Inhibition of UCH-L3 (unknown origin) using Ub-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by flu...				J Med Chem 61: 422-443 (2018) Article DOI: 10.1021/acs.jmedchem.7b00498 BindingDB Entry DOI: 10.7270/Q2CR5WVG
Progenra, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM50608424 (CHEMBL5267683) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	UniChem		n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM23425 (ChemBridge CNS-Set 7909542, 5 \| N-{3-[1-acetyl-5-(...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.31E+5	n/a	n/a	n/a	n/a	7.8	22
Waseda University					Assay Description Enzyme reactions were carried out on Costar 96-well black assay plates. After the reaction, AMC fluorescence (excitation wavelength: 355 nm, emission...				Bioorg Med Chem 15: 6810-8 (2007) Article DOI: 10.1016/j.bmc.2007.07.016 BindingDB Entry DOI: 10.7270/Q2ZK5DZK
Waseda University					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM23424 (ChemBridge CNS-Set 6382507, 4 \| N-cyclopropyl-2-[(...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.34E+5	n/a	n/a	n/a	n/a	7.8	22
Waseda University					Assay Description Enzyme reactions were carried out on Costar 96-well black assay plates. After the reaction, AMC fluorescence (excitation wavelength: 355 nm, emission...				Bioorg Med Chem 15: 6810-8 (2007) Article DOI: 10.1016/j.bmc.2007.07.016 BindingDB Entry DOI: 10.7270/Q2ZK5DZK
Waseda University					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM23429 (2-[benzene(3-methoxyphenyl)sulfonamido]-N-cyclopen...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.86E+5	n/a	n/a	n/a	n/a	7.8	22
Waseda University					Assay Description Enzyme reactions were carried out on Costar 96-well black assay plates. After the reaction, AMC fluorescence (excitation wavelength: 355 nm, emission...				Bioorg Med Chem 15: 6810-8 (2007) Article DOI: 10.1016/j.bmc.2007.07.016 BindingDB Entry DOI: 10.7270/Q2ZK5DZK
Waseda University					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM23430 (4-({[5-(furan-2-yl)-4-phenyl-4H-1,2,4-triazol-3-yl...) Show SMILES Nc1nc(CSc2nnc(-c3ccco3)n2-c2ccccc2)cs1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.87E+5	n/a	n/a	n/a	n/a	7.8	22
Waseda University					Assay Description Enzyme reactions were carried out on Costar 96-well black assay plates. After the reaction, AMC fluorescence (excitation wavelength: 355 nm, emission...				Bioorg Med Chem 15: 6810-8 (2007) Article DOI: 10.1016/j.bmc.2007.07.016 BindingDB Entry DOI: 10.7270/Q2ZK5DZK
Waseda University					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L3 (Homo sapiens (Human))	BDBM23428 (ChemBridge CNS-Set 6699002, 8 \| N-cyclopropyl-2-[(...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>4.01E+5	n/a	n/a	n/a	n/a	7.8	22
Waseda University					Assay Description Enzyme reactions were carried out on Costar 96-well black assay plates. After the reaction, AMC fluorescence (excitation wavelength: 355 nm, emission...				Bioorg Med Chem 15: 6810-8 (2007) Article DOI: 10.1016/j.bmc.2007.07.016 BindingDB Entry DOI: 10.7270/Q2ZK5DZK
Waseda University					More data for this Ligand-Target Pair