Compile Data Set for Download or QSAR

Found 35 hits of ic50 data for polymerid = 2445,50004827   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23971 ((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23971 ((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...) Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Chimie Organique et Bioorganique, FRE3252, ENSCMu, F-68093 Mulhouse Cedex, France. Curated by ChEMBL					Assay Description Inhibition of bovine lens cytosolic leucine aminopeptidase by Dixon plot analysis				Bioorg Med Chem 19: 1434-49 (2011) Article DOI: 10.1016/j.bmc.2011.01.008 BindingDB Entry DOI: 10.7270/Q2G44QJQ
					More data for this Ligand-Target Pair
Transforming growth factor beta-1 proprotein (Homo sapiens (Human))	BDBM50353187 (CHEMBL1829511) Show SMILES CN(C)CCCOc1ccc(cn1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1 Show InChI InChI=1S/C23H24N6O/c1-29(2)12-5-13-30-22-8-7-18(15-26-22)21-14-17(9-11-25-21)19-16-27-28-23(19)20-6-3-4-10-24-20/h3-4,6-11,14-16H,5,12-13H2,1-2H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...				Bioorg Med Chem Lett 21: 5642-5 (2011) Article DOI: 10.1016/j.bmcl.2010.12.120 BindingDB Entry DOI: 10.7270/Q2K937X4
					More data for this Ligand-Target Pair
Transforming growth factor beta-1 proprotein (Homo sapiens (Human))	BDBM50184879 (CHEMBL424676 | dimethyl-{2-[(4-{4-[3-(pyridin-2-yl...) Show SMILES CN(C)CCOc1ccc(cc1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1 Show InChI InChI=1S/C23H23N5O/c1-28(2)13-14-29-19-8-6-17(7-9-19)22-15-18(10-12-25-22)20-16-26-27-23(20)21-5-3-4-11-24-21/h3-12,15-16H,13-14H2,1-2H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...				Bioorg Med Chem Lett 21: 5642-5 (2011) Article DOI: 10.1016/j.bmcl.2010.12.120 BindingDB Entry DOI: 10.7270/Q2K937X4
					More data for this Ligand-Target Pair
Transforming growth factor beta-1 proprotein (Homo sapiens (Human))	BDBM50353188 (CHEMBL1829512) Show SMILES CN1CCN(CC1)c1ccc(cn1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1 Show InChI InChI=1S/C23H23N7/c1-29-10-12-30(13-11-29)22-6-5-18(15-26-22)21-14-17(7-9-25-21)19-16-27-28-23(19)20-4-2-3-8-24-20/h2-9,14-16H,10-13H2,1H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...				Bioorg Med Chem Lett 21: 5642-5 (2011) Article DOI: 10.1016/j.bmcl.2010.12.120 BindingDB Entry DOI: 10.7270/Q2K937X4
					More data for this Ligand-Target Pair
Transforming growth factor beta-1 proprotein (Homo sapiens (Human))	BDBM50353184 (CHEMBL1828640) Show SMILES Cn1cc(cn1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1 Show InChI InChI=1S/C17H14N6/c1-23-11-13(9-21-23)16-8-12(5-7-19-16)14-10-20-22-17(14)15-4-2-3-6-18-15/h2-11H,1H3,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...				Bioorg Med Chem Lett 21: 5642-5 (2011) Article DOI: 10.1016/j.bmcl.2010.12.120 BindingDB Entry DOI: 10.7270/Q2K937X4
					More data for this Ligand-Target Pair
Transforming growth factor beta-1 proprotein (Homo sapiens (Human))	BDBM50353185 (CHEMBL1829504) Show SMILES c1cnn(c1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1 Show InChI InChI=1S/C16H12N6/c1-2-6-17-14(4-1)16-13(11-19-21-16)12-5-8-18-15(10-12)22-9-3-7-20-22/h1-11H,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...				Bioorg Med Chem Lett 21: 5642-5 (2011) Article DOI: 10.1016/j.bmcl.2010.12.120 BindingDB Entry DOI: 10.7270/Q2K937X4
					More data for this Ligand-Target Pair
Transforming growth factor beta-1 proprotein (Homo sapiens (Human))	BDBM50353186 (CHEMBL1829505) Show SMILES c1cn(cn1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1 Show InChI InChI=1S/C16H12N6/c1-2-5-18-14(3-1)16-13(10-20-21-16)12-4-6-19-15(9-12)22-8-7-17-11-22/h1-11H,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...				Bioorg Med Chem Lett 21: 5642-5 (2011) Article DOI: 10.1016/j.bmcl.2010.12.120 BindingDB Entry DOI: 10.7270/Q2K937X4
					More data for this Ligand-Target Pair
Transforming growth factor beta-1 proprotein (Homo sapiens (Human))	BDBM50184872 (4-(4-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)pyridin-2-y...) Show SMILES O=C(NC1CCOCC1)c1ccc(cc1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1 Show InChI InChI=1S/C25H23N5O2/c31-25(29-20-9-13-32-14-10-20)18-6-4-17(5-7-18)23-15-19(8-12-27-23)21-16-28-30-24(21)22-3-1-2-11-26-22/h1-8,11-12,15-16,20H,9-10,13-14H2,(H,28,30)(H,29,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	446	n/a	n/a	n/a	n/a	n/a	n/a
Monash University Curated by ChEMBL					Assay Description Inhibition of TGF-beta1 signaling in human HEK293 cells transfected with luciferase and FAST-2 gene expression vector A3-LUX after 16 hrs by lucifera...				Bioorg Med Chem Lett 21: 5642-5 (2011) Article DOI: 10.1016/j.bmcl.2010.12.120 BindingDB Entry DOI: 10.7270/Q2K937X4
					More data for this Ligand-Target Pair
Transforming growth factor beta-1 proprotein (Homo sapiens (Human))	BDBM50585028 (CHEMBL5078185) Show SMILES CC[C@@H](C)[C@@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](NC(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@H](N)CC(C)C)C1CCCCC1)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H](C1CCCCC1)C(=O)N[C@H](CCCCN)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@H](Cc1ccc(O)cc1)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(N)=O |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TGF beta 1 (unknown origin) expressed in HEK293 cells transfected with Smad2/3 responsive reporter plasmid incubated for 4 hrs by dual ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00705 BindingDB Entry DOI: 10.7270/Q28S4TT7
					More data for this Ligand-Target Pair
Transforming growth factor beta-1 proprotein (Homo sapiens (Human))	BDBM50525413 (CHEMBL4448117) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)[C@@H](C)CC)[C@@H](C)CC)C1CCCCC1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C1CCCCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(N)=O |r| Show InChI InChI=1S/C114H173N29O19/c1-9-64(6)92(140-105(155)87(55-67-44-46-73(145)47-45-67)135-98(148)77(117)56-70-59-126-78-37-21-18-34-74(70)78)109(159)131-84(43-29-53-125-114(122)123)100(150)136-89(58-72-61-128-80-39-23-20-36-76(72)80)106(156)141-93(65(7)10-2)108(158)130-82(41-25-27-51-116)102(152)143-96(69-32-16-13-17-33-69)112(162)133-85(48-49-91(118)146)103(153)139-94(66(8)11-3)110(160)137-88(57-71-60-127-79-38-22-19-35-75(71)79)104(154)138-90(62-144)107(157)129-81(40-24-26-50-115)101(151)142-95(68-30-14-12-15-31-68)111(161)132-83(42-28-52-124-113(120)121)99(149)134-86(97(119)147)54-63(4)5/h18-23,34-39,44-47,59-61,63-66,68-69,77,81-90,92-96,126-128,144-145H,9-17,24-33,40-43,48-58,62,115-117H2,1-8H3,(H2,118,146)(H2,119,147)(H,129,157)(H,130,158)(H,131,159)(H,132,161)(H,133,162)(H,134,149)(H,135,148)(H,136,150)(H,137,160)(H,138,154)(H,139,153)(H,140,155)(H,141,156)(H,142,151)(H,143,152)(H4,120,121,124)(H4,122,123,125)/t64-,65-,66-,77-,81-,82-,83-,84-,85-,86-,87-,88-,89+,90-,92-,93-,94-,95-,96-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TGF beta 1 (unknown origin) expressed in HEK293 cells transfected with Smad2/3 responsive reporter plasmid incubated for 4 hrs by dual ...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00705 BindingDB Entry DOI: 10.7270/Q28S4TT7
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM50336496 (2-aminocycloheptanone hydrochloride | CHEMBL166862...) Show SMILES NC1CCCCCC1=O Show InChI InChI=1S/C7H13NO/c8-6-4-2-1-3-5-7(6)9/h6H,1-5,8H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Chimie Organique et Bioorganique, FRE3252, ENSCMu, F-68093 Mulhouse Cedex, France. Curated by ChEMBL					Assay Description Inhibition of bovine lens cytosolic leucine aminopeptidase by Dixon plot analysis				Bioorg Med Chem 19: 1434-49 (2011) Article DOI: 10.1016/j.bmc.2011.01.008 BindingDB Entry DOI: 10.7270/Q2G44QJQ
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23980 ((3Z)-3-{[(5-phenylpentyl)oxy]imino}-1,2,3,4-tetrah...) Show SMILES NC1Cc2ccccc2C\C1=N\OCCCCCc1ccccc1 Show InChI InChI=1S/C21H26N2O/c22-20-15-18-12-6-7-13-19(18)16-21(20)23-24-14-8-2-5-11-17-9-3-1-4-10-17/h1,3-4,6-7,9-10,12-13,20H,2,5,8,11,14-16,22H2/b23-21-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23977 ((3Z)-3-[(2-phenylethoxy)imino]-1,2,3,4-tetrahydron...) Show SMILES NC1Cc2ccccc2C\C1=N\OCCc1ccccc1 Show InChI InChI=1S/C18H20N2O/c19-17-12-15-8-4-5-9-16(15)13-18(17)20-21-11-10-14-6-2-1-3-7-14/h1-9,17H,10-13,19H2/b20-18-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23979 ((3Z)-3-[(4-phenylbutoxy)imino]-1,2,3,4-tetrahydron...) Show SMILES NC1Cc2ccccc2C\C1=N\OCCCCc1ccccc1 Show InChI InChI=1S/C20H24N2O/c21-19-14-17-11-4-5-12-18(17)15-20(19)22-23-13-7-6-10-16-8-2-1-3-9-16/h1-5,8-9,11-12,19H,6-7,10,13-15,21H2/b22-20-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23973 (3-amino-1,2,3,4-tetrahydronaphthalen-2-one hydroch...) Show SMILES NC1Cc2ccccc2CC1=O Show InChI InChI=1S/C10H11NO/c11-9-5-7-3-1-2-4-8(7)6-10(9)12/h1-4,9H,5-6,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23973 (3-amino-1,2,3,4-tetrahydronaphthalen-2-one hydroch...) Show SMILES NC1Cc2ccccc2CC1=O Show InChI InChI=1S/C10H11NO/c11-9-5-7-3-1-2-4-8(7)6-10(9)12/h1-4,9H,5-6,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Chimie Organique et Bioorganique, FRE3252, ENSCMu, F-68093 Mulhouse Cedex, France. Curated by ChEMBL					Assay Description Inhibition of bovine lens cytosolic leucine aminopeptidase by Dixon plot analysis				Bioorg Med Chem 19: 1434-49 (2011) Article DOI: 10.1016/j.bmc.2011.01.008 BindingDB Entry DOI: 10.7270/Q2G44QJQ
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23990 (3-amino-1,2,3,4-tetrahydroquinolin-2-one hydrochlo...) Show SMILES NC1Cc2ccccc2NC1=O Show InChI InChI=1S/C9H10N2O/c10-7-5-6-3-1-2-4-8(6)11-9(7)12/h1-4,7H,5,10H2,(H,11,12)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23988 (2-amino-1,2,3,4-tetrahydroisoquinolin-3-one | N-Su...) Show SMILES NN1Cc2ccccc2CC1=O Show InChI InChI=1S/C9H10N2O/c10-11-6-8-4-2-1-3-7(8)5-9(11)12/h1-4H,5-6,10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23974 ((3Z)-3-(hydroxyimino)-1,2,3,4-tetrahydronaphthalen...) Show SMILES ONC1Cc2ccccc2CC1=N Show InChI InChI=1S/C10H12N2O/c11-9-5-7-3-1-2-4-8(7)6-10(9)12-13/h1-4,10-13H,5-6H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM50336493 (1-Aminoindan-2-one, hydrochloride | CHEMBL1668624) Show SMILES NC1C(=O)Cc2ccccc12 Show InChI InChI=1S/C9H9NO/c10-9-7-4-2-1-3-6(7)5-8(9)11/h1-4,9H,5,10H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Chimie Organique et Bioorganique, FRE3252, ENSCMu, F-68093 Mulhouse Cedex, France. Curated by ChEMBL					Assay Description Inhibition of bovine lens cytosolic leucine aminopeptidase by Dixon plot analysis				Bioorg Med Chem 19: 1434-49 (2011) Article DOI: 10.1016/j.bmc.2011.01.008 BindingDB Entry DOI: 10.7270/Q2G44QJQ
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM50336494 (6-amino-5,6,8,9-tetrahydrobenzocycloheptene-7-one,...) Show SMILES NC1Cc2ccccc2CCC1=O Show InChI InChI=1S/C11H13NO/c12-10-7-9-4-2-1-3-8(9)5-6-11(10)13/h1-4,10H,5-7,12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Chimie Organique et Bioorganique, FRE3252, ENSCMu, F-68093 Mulhouse Cedex, France. Curated by ChEMBL					Assay Description Inhibition of bovine lens cytosolic leucine aminopeptidase by Dixon plot analysis				Bioorg Med Chem 19: 1434-49 (2011) Article DOI: 10.1016/j.bmc.2011.01.008 BindingDB Entry DOI: 10.7270/Q2G44QJQ
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM50336495 (7-Amino-5,7,8,9-tetrahydro-benzocyclohepten-6-one,...) Show SMILES NC1CCc2ccccc2CC1=O Show InChI InChI=1S/C11H13NO/c12-10-6-5-8-3-1-2-4-9(8)7-11(10)13/h1-4,10H,5-7,12H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Chimie Organique et Bioorganique, FRE3252, ENSCMu, F-68093 Mulhouse Cedex, France. Curated by ChEMBL					Assay Description Inhibition of bovine lens cytosolic leucine aminopeptidase by Dixon plot analysis				Bioorg Med Chem 19: 1434-49 (2011) Article DOI: 10.1016/j.bmc.2011.01.008 BindingDB Entry DOI: 10.7270/Q2G44QJQ
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23986 (3,4-dihydro-1H-2-benzothiopyran-3-one | isothiochr...) Show SMILES O=C1Cc2ccccc2CS1 Show InChI InChI=1S/C9H8OS/c10-9-5-7-3-1-2-4-8(7)6-11-9/h1-4H,5-6H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM50336497 (7-Amino-5,7,8,9-tetrahydrobenzocyclohepten-6-one,6...) Show SMILES ONC1Cc2ccccc2CCC1=N Show InChI InChI=1S/C11H14N2O/c12-10-6-5-8-3-1-2-4-9(8)7-11(10)13-14/h1-4,11-14H,5-7H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Chimie Organique et Bioorganique, FRE3252, ENSCMu, F-68093 Mulhouse Cedex, France. Curated by ChEMBL					Assay Description Inhibition of bovine lens cytosolic leucine aminopeptidase by Dixon plot analysis				Bioorg Med Chem 19: 1434-49 (2011) Article DOI: 10.1016/j.bmc.2011.01.008 BindingDB Entry DOI: 10.7270/Q2G44QJQ
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM50336499 (CHEMBL1668630 | cis-7-amino-6,7,8,9-tetrahydro-5H-...) Show SMILES N[C@H]1CCc2ccccc2C[C@H]1O |r| Show InChI InChI=1S/C11H15NO/c12-10-6-5-8-3-1-2-4-9(8)7-11(10)13/h1-4,10-11,13H,5-7,12H2/t10-,11+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Laboratoire de Chimie Organique et Bioorganique, FRE3252, ENSCMu, F-68093 Mulhouse Cedex, France. Curated by ChEMBL					Assay Description Inhibition of bovine lens cytosolic leucine aminopeptidase by Dixon plot analysis				Bioorg Med Chem 19: 1434-49 (2011) Article DOI: 10.1016/j.bmc.2011.01.008 BindingDB Entry DOI: 10.7270/Q2G44QJQ
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23985 (3,4-dihydro-1H-2-benzopyran-3-one | isochromanone,...) Show SMILES O=C1Cc2ccccc2CO1 Show InChI InChI=1S/C9H8O2/c10-9-5-7-3-1-2-4-8(7)6-11-9/h1-4H,5-6H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23984 (3-amino-1,2,3,4-tetrahydronaphthalene-2-phosphonic...) Show SMILES OP(O)(O)C1Cc2ccccc2CC1=N Show InChI InChI=1S/C10H14NO3P/c11-9-5-7-3-1-2-4-8(7)6-10(9)15(12,13)14/h1-4,10-15H,5-6H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23982 (1-(3-amino-1,2,3,4-tetrahydronaphthalen-2-yl)ethan...) Show SMILES CC(=O)C1Cc2ccccc2CC1N Show InChI InChI=1S/C12H15NO/c1-8(14)11-6-9-4-2-3-5-10(9)7-12(11)13/h2-5,11-12H,6-7,13H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23981 ((2S)-1,2,3,4-Tetrahydro-naphthalen-2-ylamine | 1,2...) Show SMILES NC1CCc2ccccc2C1 Show InChI InChI=1S/C10H13N/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-4,10H,5-7,11H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23978 ((3Z)-3-[(3-phenylpropoxy)imino]-1,2,3,4-tetrahydro...) Show SMILES NC1Cc2ccccc2C\C1=N\OCCCc1ccccc1 Show InChI InChI=1S/C19H22N2O/c20-18-13-16-10-4-5-11-17(16)14-19(18)21-22-12-6-9-15-7-2-1-3-8-15/h1-5,7-8,10-11,18H,6,9,12-14,20H2/b21-19-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23976 ((3Z)-3-[(benzyloxy)imino]-1,2,3,4-tetrahydronaphth...) Show SMILES NC1Cc2ccccc2C\C1=N\OCc1ccccc1 Show InChI InChI=1S/C17H18N2O/c18-16-10-14-8-4-5-9-15(14)11-17(16)19-20-12-13-6-2-1-3-7-13/h1-9,16H,10-12,18H2/b19-17-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23975 ((3Z)-3-(methoxyimino)-1,2,3,4-tetrahydronaphthalen...) Show SMILES CO\N=C1\Cc2ccccc2CC1N Show InChI InChI=1S/C11H14N2O/c1-14-13-11-7-9-5-3-2-4-8(9)6-10(11)12/h2-5,10H,6-7,12H2,1H3/b13-11-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23989 (1,2,3,4-tetrahydronaphthalen-2-one | CHEMBL191664 ...) Show SMILES O=C1CCc2ccccc2C1 Show InChI InChI=1S/C10H10O/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-4H,5-7H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair
Cytosol aminopeptidase (Bos taurus (bovine))	BDBM23987 (2-hydroxy-1,2,3,4-tetrahydroisoquinolin-3-one | CH...) Show SMILES ON1Cc2ccccc2CC1=O Show InChI InChI=1S/C9H9NO2/c11-9-5-7-3-1-2-4-8(7)6-10(9)12/h1-4,12H,5-6H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	8.0	30
ENSCMu					Assay Description Spectrophotometric assays were performed by monitoring hydrolysis of chromogenic substrate. The release of para-nitroaniline at 405 nm was measured t...				Bioorg Med Chem 14: 7241-57 (2006) Article DOI: 10.1016/j.bmc.2006.06.050 BindingDB Entry DOI: 10.7270/Q2N29V73
					More data for this Ligand-Target Pair