BindingDB PrimarySearch

Found 6 hits of ec50 data for polymerid = 2457,49000583
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gamma-aminobutyric acid type B receptor subunit 1 (Homo sapiens (Human))	BDBM86283 (CAS_345-78-8 \| CAS_39069-52-8 \| GS 39783 \| N,N'...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	79	n/a	n/a	n/a	n/a
IntelliSyn Pharma Curated by ChEMBL					Assay Description Positive allosteric modulation at human GABA-B 1b expressed in CHO cells co-expressing rat GABA-B2 assessed as potentiation of GABA-induced inhibitio...				Bioorg Med Chem Lett 27: 2239-2258 (2017) Article DOI: 10.1016/j.bmcl.2017.03.084 BindingDB Entry DOI: 10.7270/Q2VT1VJJ
IntelliSyn Pharma Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1 (Homo sapiens (Human))	BDBM24183 (4-amino-n-[2,3-3H]butyric acid \| 4-aminobutanoic a...) Show SMILES NCCCC(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Agonist activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...				J Med Chem 51: 3825-40 (2008) Article DOI: 10.1021/jm7015842 BindingDB Entry DOI: 10.7270/Q27M07RR
University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-aminobutyric acid type B receptor subunit 1 (Homo sapiens (Human))	BDBM50243872 ((+/-)-4-Amino-1-cyclopent-1-enyl(methyl)phosphinic...) Show SMILES CP(O)(=O)C1=CCC(N)C1 \|t:4\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Agonist activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...				J Med Chem 51: 3825-40 (2008) Article DOI: 10.1021/jm7015842 BindingDB Entry DOI: 10.7270/Q27M07RR
University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Homo sapiens (Human))	BDBM50243874 ((+)-(S)-4-Amino-1-cyclopent-1-enyl(methyl)phosphin...) Show SMILES CP(O)(=O)C1=CC[C@H](N)C1 \|r,t:4\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.22E+4	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Agonist activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...				J Med Chem 51: 3825-40 (2008) Article DOI: 10.1021/jm7015842 BindingDB Entry DOI: 10.7270/Q27M07RR
University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Homo sapiens (Human))	BDBM50243873 ((-)-(R)-4-Amino-1-cyclopent-1-enyl(methyl)phosphin...) Show SMILES CP(O)(=O)C1=CC[C@@H](N)C1 \|r,t:4\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7.19E+4	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Agonist activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...				J Med Chem 51: 3825-40 (2008) Article DOI: 10.1021/jm7015842 BindingDB Entry DOI: 10.7270/Q27M07RR
University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid type B receptor subunit 1 (Homo sapiens (Human))	BDBM50211642 (CHEMBL397209 \| Methyl(1,2,3,6-tetrahydropyridinium...) Show SMILES CP(O)(=O)C1=CCNCC1 \|t:4\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a
University of Sydney Curated by ChEMBL					Assay Description Agonist activity at human GABAb 1A/2 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp m...				J Med Chem 51: 3825-40 (2008) Article DOI: 10.1021/jm7015842 BindingDB Entry DOI: 10.7270/Q27M07RR
University of Sydney Curated by ChEMBL					More data for this Ligand-Target Pair