Compile Data Set for Download or QSAR

Found 96 hits of ic50 for UniProtKB: P04049   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210020 (US10576087, Compound 2.26 | US9273046, 2.26 | US98...) Show SMILES Clc1cccc2nc([nH]c12)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.25	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210052 (US10576087, Compound 2.30 | US9273046, 2.30) Show SMILES O=C1CCc2c(Oc3ccc4OC5C(C5c4c3)c3nc(c[nH]3)-c3ccccc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.25	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210051 (US10576087, Compound 2.29 | US9273046, 2.29 | US98...) Show SMILES O=C1CCc2c(Oc3ccc4OC5C(C5c4c3)c3nc(no3)-c3ccccc3)ccnc2N1 Show InChI InChI=1S/C25H18N4O4/c30-19-9-7-15-18(10-11-26-24(15)27-19)31-14-6-8-17-16(12-14)20-21(22(20)32-17)25-28-23(29-33-25)13-4-2-1-3-5-13/h1-6,8,10-12,20-22H,7,9H2,(H,26,27,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.25	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210021 (US10576087, Compound 2.27 | US9273046, 2.27 | US98...) Show SMILES Oc1ccc2nc([nH]c2c1)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.25	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210037 (US10576087, Compound 2.1 | US9273046, 2.1 | US9895...) Show SMILES O=C1CCc2c(Oc3ccc4OC5C(C5c4c3)c3nc4ccccc4[nH]3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210022 (US10576087, Compound 2.31 | US9273046, 2.31 | US98...) Show SMILES O=C1CCc2c(Oc3ccc4OC5C(C5c4c3)c3nc(c[nH]3)-c3ccncc3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.350	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210015 (US10576087, Compound 2.21 | US9273046, 2.21 | US98...) Show SMILES O=C1CCc2c(Oc3ccc4OC5C(C5c4c3)c3nc4cc5CCCc5cc4[nH]3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM372977 (US10576087, Compound 2.4a | US9895376, Compound 2....) Show SMILES Cc1cc2[nH]c(nc2cc1F)[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.540	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210044 (US10576087, Compound 2.4 | US9273046, 2.4 | US9895...) Show SMILES Cc1cc2[nH]c(nc2cc1F)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.560	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210024 (US10576087, Compound 2.33 | US9273046, 2.33 | US98...) Show SMILES FC(F)(F)c1c[nH]c(n1)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210002 (US10576087, Compound 2.8 | US9273046, 2.8 | US9895...) Show SMILES Cc1ccc2nc([nH]c2c1)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.710	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210023 (US10576087, Compound 2.32 | US9273046, 2.32 | US98...) Show SMILES Clc1ccccc1-c1c[nH]c(n1)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210016 (US10576087, Compound 2.22 | US9273046, 2.22 | US98...) Show SMILES NC(=O)c1ccc2nc([nH]c2c1)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM372967 (US10576087, Compound 2.2a | US9895376, Compound 2....) Show SMILES FC(F)(F)c1ccc2nc([nH]c2c1)[C@H]1[C@@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@H]12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210034 (US10576087, Compound 1.1 | US9273046, 1.1 | US9895...) Show SMILES O=C1CCc2c(Oc3ccc4CC5C(C5c4c3)c3nc4ccccc4[nH]3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210038 (US10576087, Compound 2.2 | US9273046, 2.2 | US9895...) Show SMILES FC(F)(F)c1ccc2nc([nH]c2c1)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210013 (US10576087, Compound 2.19 | US9273046, 2.19 | US98...) Show SMILES Fc1cccc2nc([nH]c12)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210007 (US10576087, Compound 2.13 | US9273046, 2.13 | US98...) Show SMILES Brc1ccc2nc([nH]c2c1)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210001 (US10576087, Compound 2.7 | US9273046, 2.7 | US9895...) Show SMILES Fc1ccc2nc([nH]c2c1)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM372978 (US10576087, Compound 2.4b | US9895376, Compound 2....) Show SMILES Cc1cc2[nH]c(nc2cc1F)[C@H]1[C@@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@H]12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM372985 (US10576087, Compound 2.5b | US9895376, Compound 2....) Show SMILES FC(F)(F)c1cc2[nH]c(nc2cc1Cl)[C@H]1[C@@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@H]12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM372974 (US10576087, Compound 2.3a | US9895376, Compound 2....) Show SMILES Clc1cc2nc([nH]c2cc1Cl)[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210032 (US10576087, Compound 3.7 | US9273046, 3.7 | US9895...) Show SMILES FC(F)(F)c1ccc2nc([nH]c2c1)C1C2Oc3ccc(Oc4ccnc5NC(=O)OCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210005 (US10576087, Compound 2.11 | US9273046, 2.11 | US98...) Show SMILES Fc1cc2nc([nH]c2cc1F)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210009 (US10576087, Compound 2.15 | US9273046, 2.15 | US98...) Show SMILES Cn1c(nc2ccccc12)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI InChI=1S/C25H20N4O3/c1-29-17-5-3-2-4-16(17)27-25(29)22-21-15-12-13(6-8-18(15)32-23(21)22)31-19-10-11-26-24-14(19)7-9-20(30)28-24/h2-6,8,10-12,21-23H,7,9H2,1H3,(H,26,28,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210010 (US10576087, Compound 2.16 | US9273046, 2.16 | US98...) Show SMILES COc1ccc2nc([nH]c2c1)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM372973 (US10576087, Compound 2.3b | US9895376, Compound 2....) Show SMILES Clc1cc2nc([nH]c2cc1Cl)[C@H]1[C@@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@H]12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210006 (US10576087, Compound 2.12 | US9273046, 2.12 | US98...) Show SMILES Clc1ccc2nc([nH]c2c1)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210025 (US10576087, Compound 2.34 | US9273046, 2.34 | US98...) Show SMILES OCCn1c(nc2cc(ccc12)C(F)(F)F)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI InChI=1S/C27H21F3N4O4/c28-27(29,30)13-1-4-18-17(11-13)32-26(34(18)9-10-35)23-22-16-12-14(2-5-19(16)38-24(22)23)37-20-7-8-31-25-15(20)3-6-21(36)33-25/h1-2,4-5,7-8,11-12,22-24,35H,3,6,9-10H2,(H,31,33,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210018 (US10576087, Compound 2.24 | US9273046, 2.24 | US98...) Show SMILES Cn1c(nc2cc(ccc12)C(F)(F)F)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI InChI=1S/C26H19F3N4O3/c1-33-17-5-2-12(26(27,28)29)10-16(17)31-25(33)22-21-15-11-13(3-6-18(15)36-23(21)22)35-19-8-9-30-24-14(19)4-7-20(34)32-24/h2-3,5-6,8-11,21-23H,4,7H2,1H3,(H,30,32,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210014 (US10576087, Compound 2.20 | US9273046, 2.20 | US98...) Show SMILES CC(C)(C)c1ccc2nc([nH]c2c1)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210003 (US10576087, Compound 2.9 | US9273046, 2.9 | US9895...) Show SMILES O=C1CCc2c(Oc3ccc4OC5C(C5c4c3)c3nc4ccncc4[nH]3)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210000 (US10576087, Compound 2.6 | US9273046, 2.6 | US9895...) Show SMILES O=C1CCc2c(Oc3ccc4OC5C(C5c4c3)c3nc4ccc(cc4[nH]3)C#N)ccnc2N1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210041 (US10576087, Compound 2.3 | US9273046, 2.3 | US9895...) Show SMILES Clc1cc2nc([nH]c2cc1Cl)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210047 (US10576087, Compound 2.5 | US9273046, 2.5 | US9895...) Show SMILES FC(F)(F)c1cc2[nH]c(nc2cc1Cl)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210036 (US10576087, Compound 1.3 | US9273046, 1.3) Show SMILES O=C1CCc2c(Oc3ccc4CC5C(C5c4c3)c3nc4ccccc4s3)ccnc2N1 Show InChI InChI=1S/C25H19N3O2S/c29-21-8-7-15-19(9-10-26-24(15)28-21)30-14-6-5-13-11-17-22(16(13)12-14)23(17)25-27-18-3-1-2-4-20(18)31-25/h1-6,9-10,12,17,22-23H,7-8,11H2,(H,26,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210011 (US10576087, Compound 2.17 | US9273046, 2.17 | US98...) Show SMILES Fc1cc2[nH]c(nc2cc1Cl)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210012 (US10576087, Compound 2.18 | US9273046, 2.18 | US98...) Show SMILES FC(F)(F)c1cccc2nc([nH]c12)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210028 (US10576087, Compound 3.1 | US9273046, 3.1) Show SMILES CNC(=O)c1cc(Oc2ccc3OC4C(C4c3c2)c2nc3ccc(cc3[nH]2)C(F)(F)F)ccn1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM372968 (US10576087, Compound 2.2b | US9895376, Compound 2....) Show SMILES FC(F)(F)c1ccc2nc([nH]c2c1)[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210008 (US10576087, Compound 2.14 | US9273046, 2.14 | US98...) Show SMILES FC(F)(F)Oc1ccc2nc([nH]c2c1)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210057 (US10576087, Compound 2.35 | US9273046, 2.35 | US98...) Show SMILES Cc1cc(Oc2ccnc3NC(=O)CCc23)cc2C3C(Oc12)C3c1nc2ccc(cc2[nH]1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210035 (US10576087, Compound 1.2 | US9273046, 1.2 | US9895...) Show SMILES FC(F)(F)c1ccc2nc([nH]c2c1)C1C2Cc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210053 (US10576087, Compound 3.5 | US9273046, 3.5 | US9895...) Show SMILES FC(F)(F)c1ccc2nc([nH]c2c1)C1C2Oc3ccc(Oc4ncnc5[nH]cnc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM372981 (US10576087, Compound 2.5a | US9895376, Compound 2....) Show SMILES FC(F)(F)c1cc2[nH]c(nc2cc1Cl)[C@@H]1[C@H]2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3[C@@H]12 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210027 (US10576087, Compound 2.37 | US9273046, 2.37 | US98...) Show SMILES Cc1cc2nc([nH]c2cc1F)C1C2Oc3cc(Cl)c(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210004 (US10576087, Compound 2.10 | US9273046, 2.10 | US98...) Show SMILES FC(F)(F)c1cc(Cl)c2nc([nH]c2c1)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210026 (US10576087, Compound 2.36 | US9273046, 2.36 | US98...) Show SMILES FC(F)(F)c1ccc2nc([nH]c2c1)C1C2Oc3cc(Cl)c(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210017 (US10576087, Compound 2.23 | US9273046, 2.23 | US98...) Show SMILES Cn1c(nc2ccc(cc12)C(F)(F)F)C1C2Oc3ccc(Oc4ccnc5NC(=O)CCc45)cc3C12 Show InChI InChI=1S/C26H19F3N4O3/c1-33-17-10-12(26(27,28)29)2-5-16(17)31-25(33)22-21-15-11-13(3-6-18(15)36-23(21)22)35-19-8-9-30-24-14(19)4-7-20(34)32-24/h2-3,5-6,8-11,21-23H,4,7H2,1H3,(H,30,32,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair
RAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D] (Homo sapiens (Human))	BDBM210019 (US10576087, Compound 2.25 | US9273046, 2.25 | US98...) Show SMILES FC(F)(F)c1ccc2nc([nH]c2c1)C1C2Oc3c(cccc3Oc3ccnc4NC(=O)CCc34)C12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
BEIGENE, LTD. US Patent					Assay Description Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...				US Patent US10576087 (2020) BindingDB Entry DOI: 10.7270/Q2HM5BVQ
					More data for this Ligand-Target Pair

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