Found 224 hits of ic50 data for polymerid = 4601,50006191 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50121716
((3-methyl-4-(3-(pyridin-3-ylmethylamino)propoxy)be...)Show SMILES Cc1c(oc2cccc(OCCCNCc3cccnc3)c12)C(=O)c1ccc(C)cn1 Show InChI InChI=1S/C25H25N3O3/c1-17-9-10-20(28-14-17)24(29)25-18(2)23-21(7-3-8-22(23)31-25)30-13-5-12-27-16-19-6-4-11-26-15-19/h3-4,6-11,14-15,27H,5,12-13,16H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.390 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50121716
((3-methyl-4-(3-(pyridin-3-ylmethylamino)propoxy)be...)Show SMILES Cc1c(oc2cccc(OCCCNCc3cccnc3)c12)C(=O)c1ccc(C)cn1 Show InChI InChI=1S/C25H25N3O3/c1-17-9-10-20(28-14-17)24(29)25-18(2)23-21(7-3-8-22(23)31-25)30-13-5-12-27-16-19-6-4-11-26-15-19/h3-4,6-11,14-15,27H,5,12-13,16H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.390 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50457393
(CHEMBL3220375)Show SMILES O=C(Nc1nc2ccc(NC(=O)[C@@H]3CCC[C@@H](C3)NCc3ccc4ccccc4c3)cc2s1)C1CCCC1 |r| Show InChI InChI=1S/C31H34N4O2S/c36-29(22-7-2-3-8-22)35-31-34-27-15-14-26(18-28(27)38-31)33-30(37)24-10-5-11-25(17-24)32-19-20-12-13-21-6-1-4-9-23(21)16-20/h1,4,6,9,12-16,18,22,24-25,32H,2-3,5,7-8,10-11,17,19H2,(H,33,37)(H,34,35,36)/t24-,25+/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 0.490 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans ATCC 90028 NMT using GLTISKLFRR-NH2 as substrate assessed as reduction in [3H]-myristoylated peptide reaction product ... |
J Med Chem 61: 5484-5511 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01413
BindingDB Entry DOI: 10.7270/Q26112X4 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207643
((1S,3R)-N-(2-(cyclopentanecarboxamido)benzo[d]thia...)Show SMILES O=C(Nc1nc2ccc(NC(=O)[C@H]3CCC[C@H](C3)NCc3ccc4ccccc4c3)cc2s1)C1CCCC1 Show InChI InChI=1S/C31H34N4O2S/c36-29(22-7-2-3-8-22)35-31-34-27-15-14-26(18-28(27)38-31)33-30(37)24-10-5-11-25(17-24)32-19-20-12-13-21-6-1-4-9-23(21)16-20/h1,4,6,9,12-16,18,22,24-25,32H,2-3,5,7-8,10-11,17,19H2,(H,33,37)(H,34,35,36)/t24-,25+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 0.490 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207643
((1S,3R)-N-(2-(cyclopentanecarboxamido)benzo[d]thia...)Show SMILES O=C(Nc1nc2ccc(NC(=O)[C@H]3CCC[C@H](C3)NCc3ccc4ccccc4c3)cc2s1)C1CCCC1 Show InChI InChI=1S/C31H34N4O2S/c36-29(22-7-2-3-8-22)35-31-34-27-15-14-26(18-28(27)38-31)33-30(37)24-10-5-11-25(17-24)32-19-20-12-13-21-6-1-4-9-23(21)16-20/h1,4,6,9,12-16,18,22,24-25,32H,2-3,5,7-8,10-11,17,19H2,(H,33,37)(H,34,35,36)/t24-,25+/m0/s1 | PDB
MMDB
KEGG
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DrugBank
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 0.490 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50121720
((1-METHYL-1H-IMIDAZOL-2-YL)-(3-METHYL-4-{3-[(PYRID...)Show SMILES Cc1c(oc2cccc(OCCCNCc3cccnc3)c12)C(=O)c1nccn1C Show InChI InChI=1S/C23H24N4O3/c1-16-20-18(29-13-5-10-25-15-17-6-4-9-24-14-17)7-3-8-19(20)30-22(16)21(28)23-26-11-12-27(23)2/h3-4,6-9,11-12,14,25H,5,10,13,15H2,1-2H3 | PDB
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| CHEMBL
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PC cid
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| DrugBank
MMDB
PDB
Article
PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center
| Assay Description
Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... |
Chem Biol 9: 1119-28 (2002)
Article DOI: 10.1016/S1074-5521(02)00240-5
BindingDB Entry DOI: 10.7270/Q2BV7F0C |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207640
(CHEMBL254011 | N-(2-(cyclobutanecarboxamido)benzo[...)Show SMILES O=C(Nc1nc2ccc(NC(=O)C3CCCC(C3)NCc3ccc4ccccc4c3)cc2s1)C1CCC1 |w:16.18,12.11| Show InChI InChI=1S/C30H32N4O2S/c35-28(21-7-3-8-21)34-30-33-26-14-13-25(17-27(26)37-30)32-29(36)23-9-4-10-24(16-23)31-18-19-11-12-20-5-1-2-6-22(20)15-19/h1-2,5-6,11-15,17,21,23-24,31H,3-4,7-10,16,18H2,(H,32,36)(H,33,34,35) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207640
(CHEMBL254011 | N-(2-(cyclobutanecarboxamido)benzo[...)Show SMILES O=C(Nc1nc2ccc(NC(=O)C3CCCC(C3)NCc3ccc4ccccc4c3)cc2s1)C1CCC1 |w:16.18,12.11| Show InChI InChI=1S/C30H32N4O2S/c35-28(21-7-3-8-21)34-30-33-26-14-13-25(17-27(26)37-30)32-29(36)23-9-4-10-24(16-23)31-18-19-11-12-20-5-1-2-6-22(20)15-19/h1-2,5-6,11-15,17,21,23-24,31H,3-4,7-10,16,18H2,(H,32,36)(H,33,34,35) | PDB
MMDB
KEGG
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DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207612
(CHEMBL400892 | N-(2-(cyclopropanecarboxamido)benzo...)Show SMILES O=C(Nc1nc2ccc(NC(=O)C3CCCC(C3)NCc3ccc4ccccc4c3)cc2s1)C1CC1 |w:16.18,12.11| Show InChI InChI=1S/C29H30N4O2S/c34-27(20-10-11-20)33-29-32-25-13-12-24(16-26(25)36-29)31-28(35)22-6-3-7-23(15-22)30-17-18-8-9-19-4-1-2-5-21(19)14-18/h1-2,4-5,8-9,12-14,16,20,22-23,30H,3,6-7,10-11,15,17H2,(H,31,35)(H,32,33,34) | PDB
MMDB
KEGG
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DrugBank
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207612
(CHEMBL400892 | N-(2-(cyclopropanecarboxamido)benzo...)Show SMILES O=C(Nc1nc2ccc(NC(=O)C3CCCC(C3)NCc3ccc4ccccc4c3)cc2s1)C1CC1 |w:16.18,12.11| Show InChI InChI=1S/C29H30N4O2S/c34-27(20-10-11-20)33-29-32-25-13-12-24(16-26(25)36-29)31-28(35)22-6-3-7-23(15-22)30-17-18-8-9-19-4-1-2-5-21(19)14-18/h1-2,4-5,8-9,12-14,16,20,22-23,30H,3,6-7,10-11,15,17H2,(H,31,35)(H,32,33,34) | PDB
MMDB
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207620
(CHEMBL254010 | N-(2-isobutyramidobenzo[d]thiazol-6...)Show SMILES CC(C)C(=O)Nc1nc2ccc(NC(=O)C3CCCC(C3)NCc3ccc4ccccc4c3)cc2s1 |w:15.14,19.21| Show InChI InChI=1S/C29H32N4O2S/c1-18(2)27(34)33-29-32-25-13-12-24(16-26(25)36-29)31-28(35)22-8-5-9-23(15-22)30-17-19-10-11-20-6-3-4-7-21(20)14-19/h3-4,6-7,10-14,16,18,22-23,30H,5,8-9,15,17H2,1-2H3,(H,31,35)(H,32,33,34) | PDB
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207620
(CHEMBL254010 | N-(2-isobutyramidobenzo[d]thiazol-6...)Show SMILES CC(C)C(=O)Nc1nc2ccc(NC(=O)C3CCCC(C3)NCc3ccc4ccccc4c3)cc2s1 |w:15.14,19.21| Show InChI InChI=1S/C29H32N4O2S/c1-18(2)27(34)33-29-32-25-13-12-24(16-26(25)36-29)31-28(35)22-8-5-9-23(15-22)30-17-19-10-11-20-6-3-4-7-21(20)14-19/h3-4,6-7,10-14,16,18,22-23,30H,5,8-9,15,17H2,1-2H3,(H,31,35)(H,32,33,34) | PDB
MMDB
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PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50109879
(CHEMBL155301 | Non peptidic, 4 | {3-[2-(2,3-Difluo...)Show SMILES Cc1c(COc2cccc(F)c2F)oc2cccc(OCCCNCc3cccnc3)c12 Show InChI InChI=1S/C25H24F2N2O3/c1-17-23(16-31-22-10-2-7-19(26)25(22)27)32-21-9-3-8-20(24(17)21)30-13-5-12-29-15-18-6-4-11-28-14-18/h2-4,6-11,14,29H,5,12-13,15-16H2,1H3 | PDB
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| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center
| Assay Description
Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... |
Chem Biol 9: 1119-28 (2002)
Article DOI: 10.1016/S1074-5521(02)00240-5
BindingDB Entry DOI: 10.7270/Q2BV7F0C |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50109882
(3-(3-methyl-2-((2,3,4-trifluorophenoxy)methyl)benz...)Show SMILES Cc1c(COc2ccc(F)c(F)c2F)oc2cccc(OCCCNCc3cccnc3)c12 Show InChI InChI=1S/C25H23F3N2O3/c1-16-22(15-32-21-9-8-18(26)24(27)25(21)28)33-20-7-2-6-19(23(16)20)31-12-4-11-30-14-17-5-3-10-29-13-17/h2-3,5-10,13,30H,4,11-12,14-15H2,1H3 | PDB
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| Article
PubMed
| n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans ATCC 90028 NMT using GLTISKLFRR-NH2 as substrate assessed as reduction in [3H]-myristoylated peptide reaction product ... |
J Med Chem 61: 5484-5511 (2018)
Article DOI: 10.1021/acs.jmedchem.7b01413
BindingDB Entry DOI: 10.7270/Q26112X4 |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50109882
(3-(3-methyl-2-((2,3,4-trifluorophenoxy)methyl)benz...)Show SMILES Cc1c(COc2ccc(F)c(F)c2F)oc2cccc(OCCCNCc3cccnc3)c12 Show InChI InChI=1S/C25H23F3N2O3/c1-16-22(15-32-21-9-8-18(26)24(27)25(21)28)33-20-7-2-6-19(23(16)20)31-12-4-11-30-14-17-5-3-10-29-13-17/h2-3,5-10,13,30H,4,11-12,14-15H2,1H3 | PDB
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PC cid
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| Article
PubMed
| n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50109882
(3-(3-methyl-2-((2,3,4-trifluorophenoxy)methyl)benz...)Show SMILES Cc1c(COc2ccc(F)c(F)c2F)oc2cccc(OCCCNCc3cccnc3)c12 Show InChI InChI=1S/C25H23F3N2O3/c1-16-22(15-32-21-9-8-18(26)24(27)25(21)28)33-20-7-2-6-19(23(16)20)31-12-4-11-30-14-17-5-3-10-29-13-17/h2-3,5-10,13,30H,4,11-12,14-15H2,1H3 | PDB
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| CHEMBL
PC cid
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| Article
PubMed
| n/a | n/a | 5.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207627
(3-[(naphthalen-2-ylmethyl)-amino]-cyclohexanecarbo...)Show SMILES O=C(Nc1nc2ccc(NC(=O)C3CCCC(C3)NCc3ccc4ccccc4c3)cc2s1)C1CCCCC1 |w:16.18,12.11| Show InChI InChI=1S/C32H36N4O2S/c37-30(23-8-2-1-3-9-23)36-32-35-28-16-15-27(19-29(28)39-32)34-31(38)25-11-6-12-26(18-25)33-20-21-13-14-22-7-4-5-10-24(22)17-21/h4-5,7,10,13-17,19,23,25-26,33H,1-3,6,8-9,11-12,18,20H2,(H,34,38)(H,35,36,37) | PDB
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| n/a | n/a | 8.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207627
(3-[(naphthalen-2-ylmethyl)-amino]-cyclohexanecarbo...)Show SMILES O=C(Nc1nc2ccc(NC(=O)C3CCCC(C3)NCc3ccc4ccccc4c3)cc2s1)C1CCCCC1 |w:16.18,12.11| Show InChI InChI=1S/C32H36N4O2S/c37-30(23-8-2-1-3-9-23)36-32-35-28-16-15-27(19-29(28)39-32)34-31(38)25-11-6-12-26(18-25)33-20-21-13-14-22-7-4-5-10-24(22)17-21/h4-5,7,10,13-17,19,23,25-26,33H,1-3,6,8-9,11-12,18,20H2,(H,34,38)(H,35,36,37) | PDB
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| n/a | n/a | 8.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207621
((1R,3S)-3-[(naphthalen-2-ylmethyl)-amino]-cyclopen...)Show SMILES O=C(Nc1nc2ccc(NC(=O)[C@@H]3CC[C@@H](C3)NCc3ccc4ccccc4c3)cc2s1)C1CCCC1 Show InChI InChI=1S/C30H32N4O2S/c35-28(21-6-2-3-7-21)34-30-33-26-14-13-25(17-27(26)37-30)32-29(36)23-11-12-24(16-23)31-18-19-9-10-20-5-1-4-8-22(20)15-19/h1,4-5,8-10,13-15,17,21,23-24,31H,2-3,6-7,11-12,16,18H2,(H,32,36)(H,33,34,35)/t23-,24+/m1/s1 | PDB
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| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207621
((1R,3S)-3-[(naphthalen-2-ylmethyl)-amino]-cyclopen...)Show SMILES O=C(Nc1nc2ccc(NC(=O)[C@@H]3CC[C@@H](C3)NCc3ccc4ccccc4c3)cc2s1)C1CCCC1 Show InChI InChI=1S/C30H32N4O2S/c35-28(21-6-2-3-7-21)34-30-33-26-14-13-25(17-27(26)37-30)32-29(36)23-11-12-24(16-23)31-18-19-9-10-20-5-1-4-8-22(20)15-19/h1,4-5,8-10,13-15,17,21,23-24,31H,2-3,6-7,11-12,16,18H2,(H,32,36)(H,33,34,35)/t23-,24+/m1/s1 | PDB
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| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207614
(CHEMBL399663 | N-(6-(4-(naphthalen-2-ylmethylamino...)Show SMILES O=C(CCCNCc1ccc2ccccc2c1)Nc1ccc2nc(NC(=O)C3CCCC3)sc2c1 Show InChI InChI=1S/C28H30N4O2S/c33-26(10-5-15-29-18-19-11-12-20-6-1-4-9-22(20)16-19)30-23-13-14-24-25(17-23)35-28(31-24)32-27(34)21-7-2-3-8-21/h1,4,6,9,11-14,16-17,21,29H,2-3,5,7-8,10,15,18H2,(H,30,33)(H,31,32,34) | PDB
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| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207614
(CHEMBL399663 | N-(6-(4-(naphthalen-2-ylmethylamino...)Show SMILES O=C(CCCNCc1ccc2ccccc2c1)Nc1ccc2nc(NC(=O)C3CCCC3)sc2c1 Show InChI InChI=1S/C28H30N4O2S/c33-26(10-5-15-29-18-19-11-12-20-6-1-4-9-22(20)16-19)30-23-13-14-24-25(17-23)35-28(31-24)32-27(34)21-7-2-3-8-21/h1,4,6,9,11-14,16-17,21,29H,2-3,5,7-8,10,15,18H2,(H,30,33)(H,31,32,34) | PDB
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| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Plasmodium falciparum (isolate 3D7)) | BDBM50496902
(CHEMBL3237438)Show SMILES Cc1nn(C)c(C)c1Cc1nnc(o1)-c1sc2ccccc2c1OC1CCNCC1 Show InChI InChI=1S/C22H25N5O2S/c1-13-17(14(2)27(3)26-13)12-19-24-25-22(29-19)21-20(28-15-8-10-23-11-9-15)16-6-4-5-7-18(16)30-21/h4-7,15,23H,8-12H2,1-3H3 | KEGG
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| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Imperial College
Curated by ChEMBL
| Assay Description
Inhibition of Plasmodium falciparum N-myristoyltransferase by CPM fluorescence assay |
J Med Chem 57: 2773-88 (2014)
Article DOI: 10.1021/jm500066b
BindingDB Entry DOI: 10.7270/Q27084DV |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207632
(2-(cyclopentanecarboxamido)-N-(2-(naphthalen-2-ylm...)Show SMILES O=C(Nc1nc2ccc(cc2s1)C(=O)NCCNCc1ccc2ccccc2c1)C1CCCC1 Show InChI InChI=1S/C27H28N4O2S/c32-25(29-14-13-28-17-18-9-10-19-5-1-4-8-21(19)15-18)22-11-12-23-24(16-22)34-27(30-23)31-26(33)20-6-2-3-7-20/h1,4-5,8-12,15-16,20,28H,2-3,6-7,13-14,17H2,(H,29,32)(H,30,31,33) | PDB
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| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207632
(2-(cyclopentanecarboxamido)-N-(2-(naphthalen-2-ylm...)Show SMILES O=C(Nc1nc2ccc(cc2s1)C(=O)NCCNCc1ccc2ccccc2c1)C1CCCC1 Show InChI InChI=1S/C27H28N4O2S/c32-25(29-14-13-28-17-18-9-10-19-5-1-4-8-21(19)15-18)22-11-12-23-24(16-22)34-27(30-23)31-26(33)20-6-2-3-7-20/h1,4-5,8-12,15-16,20,28H,2-3,6-7,13-14,17H2,(H,29,32)(H,30,31,33) | PDB
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| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207610
(CHEMBL252142 | N-(6-(4-((naphthalen-2-ylmethylamin...)Show SMILES O=C(Nc1nc2ccc(cc2s1)C(=O)N1CCC(CNCc2ccc3ccccc3c2)CC1)C1CCCCC1 Show InChI InChI=1S/C32H36N4O2S/c37-30(25-7-2-1-3-8-25)35-32-34-28-13-12-27(19-29(28)39-32)31(38)36-16-14-22(15-17-36)20-33-21-23-10-11-24-6-4-5-9-26(24)18-23/h4-6,9-13,18-19,22,25,33H,1-3,7-8,14-17,20-21H2,(H,34,35,37) | PDB
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| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207610
(CHEMBL252142 | N-(6-(4-((naphthalen-2-ylmethylamin...)Show SMILES O=C(Nc1nc2ccc(cc2s1)C(=O)N1CCC(CNCc2ccc3ccccc3c2)CC1)C1CCCCC1 Show InChI InChI=1S/C32H36N4O2S/c37-30(25-7-2-1-3-8-25)35-32-34-28-13-12-27(19-29(28)39-32)31(38)36-16-14-22(15-17-36)20-33-21-23-10-11-24-6-4-5-9-26(24)18-23/h4-6,9-13,18-19,22,25,33H,1-3,7-8,14-17,20-21H2,(H,34,35,37) | PDB
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| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207626
(2-(cyclobutanecarboxamido)-N-(2-(naphthalen-2-ylme...)Show SMILES O=C(Nc1nc2ccc(cc2s1)C(=O)NCCNCc1ccc2ccccc2c1)C1CCC1 Show InChI InChI=1S/C26H26N4O2S/c31-24(28-13-12-27-16-17-8-9-18-4-1-2-5-20(18)14-17)21-10-11-22-23(15-21)33-26(29-22)30-25(32)19-6-3-7-19/h1-2,4-5,8-11,14-15,19,27H,3,6-7,12-13,16H2,(H,28,31)(H,29,30,32) | PDB
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| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207626
(2-(cyclobutanecarboxamido)-N-(2-(naphthalen-2-ylme...)Show SMILES O=C(Nc1nc2ccc(cc2s1)C(=O)NCCNCc1ccc2ccccc2c1)C1CCC1 Show InChI InChI=1S/C26H26N4O2S/c31-24(28-13-12-27-16-17-8-9-18-4-1-2-5-20(18)14-17)21-10-11-22-23(15-21)33-26(29-22)30-25(32)19-6-3-7-19/h1-2,4-5,8-11,14-15,19,27H,3,6-7,12-13,16H2,(H,28,31)(H,29,30,32) | PDB
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| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM43856
(4-ethoxy-N-[(6-fluoro-1,1-diketo-2,3-dihydrothioch...)Show SMILES CCOc1ccc(cc1)S(=O)(=O)NN=C1CCS(=O)(=O)c2ccc(F)cc12 |w:13.13| Show InChI InChI=1S/C17H17FN2O5S2/c1-2-25-13-4-6-14(7-5-13)27(23,24)20-19-16-9-10-26(21,22)17-8-3-12(18)11-15(16)17/h3-8,11,20H,2,9-10H2,1H3 | PDB
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| 30 | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Nippon Roche Research Center
| Assay Description
Inhibition activity against C. albicans Nmt and human Nmt as assessed by IC50 using myristoyl-CoA (0.5 uM) and peptide substrate GLTISKLFRR-NH2 (0.5 ... |
Chem Biol 9: 1119-28 (2002)
Article DOI: 10.1016/S1074-5521(02)00240-5
BindingDB Entry DOI: 10.7270/Q2BV7F0C |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207615
(CHEMBL254220 | N-(2-(cyclopentanecarboxamido)benzo...)Show SMILES O=C(Nc1nc2ccc(NC(=O)C3CCC(CC3)NCc3ccc4ccccc4c3)cc2s1)C1CCCC1 |(13.06,-36.55,;13.83,-35.22,;13.06,-33.88,;11.52,-33.88,;10.61,-35.13,;9.15,-34.66,;7.81,-35.43,;6.48,-34.66,;6.48,-33.12,;5.15,-32.35,;3.81,-33.12,;3.81,-34.66,;2.48,-32.35,;2.48,-30.81,;1.16,-30.04,;-.18,-30.81,;-.19,-32.35,;1.15,-33.13,;-1.51,-30.03,;-2.85,-30.8,;-4.18,-30.02,;-4.17,-28.49,;-5.5,-27.71,;-6.83,-28.49,;-8.16,-27.71,;-9.49,-28.48,;-9.49,-30.02,;-8.16,-30.79,;-6.83,-30.03,;-5.5,-30.79,;7.81,-32.35,;9.15,-33.11,;10.61,-32.64,;15.37,-35.21,;16.28,-36.46,;17.74,-35.98,;17.74,-34.44,;16.28,-33.96,)| Show InChI InChI=1S/C31H34N4O2S/c36-29(23-11-13-25(14-12-23)32-19-20-9-10-21-5-1-4-8-24(21)17-20)33-26-15-16-27-28(18-26)38-31(34-27)35-30(37)22-6-2-3-7-22/h1,4-5,8-10,15-18,22-23,25,32H,2-3,6-7,11-14,19H2,(H,33,36)(H,34,35,37) | PDB
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| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207602
(2-(cyclohexanecarboxamido)-N-(2-(naphthalen-2-ylme...)Show SMILES O=C(Nc1nc2ccc(cc2s1)C(=O)NCCNCc1ccc2ccccc2c1)C1CCCCC1 Show InChI InChI=1S/C28H30N4O2S/c33-26(30-15-14-29-18-19-10-11-20-6-4-5-9-22(20)16-19)23-12-13-24-25(17-23)35-28(31-24)32-27(34)21-7-2-1-3-8-21/h4-6,9-13,16-17,21,29H,1-3,7-8,14-15,18H2,(H,30,33)(H,31,32,34) | PDB
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| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207602
(2-(cyclohexanecarboxamido)-N-(2-(naphthalen-2-ylme...)Show SMILES O=C(Nc1nc2ccc(cc2s1)C(=O)NCCNCc1ccc2ccccc2c1)C1CCCCC1 Show InChI InChI=1S/C28H30N4O2S/c33-26(30-15-14-29-18-19-10-11-20-6-4-5-9-22(20)16-19)23-12-13-24-25(17-23)35-28(31-24)32-27(34)21-7-2-1-3-8-21/h4-6,9-13,16-17,21,29H,1-3,7-8,14-15,18H2,(H,30,33)(H,31,32,34) | PDB
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| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207615
(CHEMBL254220 | N-(2-(cyclopentanecarboxamido)benzo...)Show SMILES O=C(Nc1nc2ccc(NC(=O)C3CCC(CC3)NCc3ccc4ccccc4c3)cc2s1)C1CCCC1 |(13.06,-36.55,;13.83,-35.22,;13.06,-33.88,;11.52,-33.88,;10.61,-35.13,;9.15,-34.66,;7.81,-35.43,;6.48,-34.66,;6.48,-33.12,;5.15,-32.35,;3.81,-33.12,;3.81,-34.66,;2.48,-32.35,;2.48,-30.81,;1.16,-30.04,;-.18,-30.81,;-.19,-32.35,;1.15,-33.13,;-1.51,-30.03,;-2.85,-30.8,;-4.18,-30.02,;-4.17,-28.49,;-5.5,-27.71,;-6.83,-28.49,;-8.16,-27.71,;-9.49,-28.48,;-9.49,-30.02,;-8.16,-30.79,;-6.83,-30.03,;-5.5,-30.79,;7.81,-32.35,;9.15,-33.11,;10.61,-32.64,;15.37,-35.21,;16.28,-36.46,;17.74,-35.98,;17.74,-34.44,;16.28,-33.96,)| Show InChI InChI=1S/C31H34N4O2S/c36-29(23-11-13-25(14-12-23)32-19-20-9-10-21-5-1-4-8-24(21)17-20)33-26-15-16-27-28(18-26)38-31(34-27)35-30(37)22-6-2-3-7-22/h1,4-5,8-10,15-18,22-23,25,32H,2-3,6-7,11-14,19H2,(H,33,36)(H,34,35,37) | PDB
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| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50057702
((S)-6-Amino-2-((S)-2-{2-[4-(6-amino-hexyl)-phenyl]...)Show SMILES CC(C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)NCCC1CCCCC1)c1ccc(CCCCCCN)cc1 Show InChI InChI=1S/C32H55N5O4/c1-24(27-17-15-26(16-18-27)13-5-2-3-9-20-33)30(39)37-29(23-38)32(41)36-28(14-8-10-21-34)31(40)35-22-19-25-11-6-4-7-12-25/h15-18,24-25,28-29,38H,2-14,19-23,33-34H2,1H3,(H,35,40)(H,36,41)(H,37,39)/t24?,28-,29-/m0/s1 | PDB
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| n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
G. D. Searle Research and Development
Curated by ChEMBL
| Assay Description
Inhibitory activity against N-myristoyltransferase (NMT) of candida albicans |
J Med Chem 40: 1422-38 (1997)
Article DOI: 10.1021/jm9608671
BindingDB Entry DOI: 10.7270/Q2GB24Q7 |
More data for this
Ligand-Target Pair |
3D Structure (docked) |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207607
(2-isobutyramido-N-(2-(naphthalen-2-ylmethylamino)e...)Show SMILES CC(C)C(=O)Nc1nc2ccc(cc2s1)C(=O)NCCNCc1ccc2ccccc2c1 Show InChI InChI=1S/C25H26N4O2S/c1-16(2)23(30)29-25-28-21-10-9-20(14-22(21)32-25)24(31)27-12-11-26-15-17-7-8-18-5-3-4-6-19(18)13-17/h3-10,13-14,16,26H,11-12,15H2,1-2H3,(H,27,31)(H,28,29,30) | PDB
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| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207607
(2-isobutyramido-N-(2-(naphthalen-2-ylmethylamino)e...)Show SMILES CC(C)C(=O)Nc1nc2ccc(cc2s1)C(=O)NCCNCc1ccc2ccccc2c1 Show InChI InChI=1S/C25H26N4O2S/c1-16(2)23(30)29-25-28-21-10-9-20(14-22(21)32-25)24(31)27-12-11-26-15-17-7-8-18-5-3-4-6-19(18)13-17/h3-10,13-14,16,26H,11-12,15H2,1-2H3,(H,27,31)(H,28,29,30) | PDB
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| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207636
(CHEMBL251943 | N-(6-(3-(naphthalen-2-ylmethylamino...)Show SMILES O=C(Nc1nc2ccc(cc2s1)C(=O)N1CC(C1)NCc1ccc2ccccc2c1)C1CCCCC1 Show InChI InChI=1S/C29H30N4O2S/c34-27(21-7-2-1-3-8-21)32-29-31-25-13-12-23(15-26(25)36-29)28(35)33-17-24(18-33)30-16-19-10-11-20-6-4-5-9-22(20)14-19/h4-6,9-15,21,24,30H,1-3,7-8,16-18H2,(H,31,32,34) | PDB
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| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207636
(CHEMBL251943 | N-(6-(3-(naphthalen-2-ylmethylamino...)Show SMILES O=C(Nc1nc2ccc(cc2s1)C(=O)N1CC(C1)NCc1ccc2ccccc2c1)C1CCCCC1 Show InChI InChI=1S/C29H30N4O2S/c34-27(21-7-2-1-3-8-21)32-29-31-25-13-12-23(15-26(25)36-29)28(35)33-17-24(18-33)30-16-19-10-11-20-6-4-5-9-22(20)14-19/h4-6,9-15,21,24,30H,1-3,7-8,16-18H2,(H,31,32,34) | PDB
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| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207601
(2-(cyclohexanecarboxamido)-N-(4-(naphthalen-2-ylme...)Show SMILES O=C(Nc1nc2ccc(cc2s1)C(=O)NCCCCNCc1ccc2ccccc2c1)C1CCCCC1 Show InChI InChI=1S/C30H34N4O2S/c35-28(32-17-7-6-16-31-20-21-12-13-22-8-4-5-11-24(22)18-21)25-14-15-26-27(19-25)37-30(33-26)34-29(36)23-9-2-1-3-10-23/h4-5,8,11-15,18-19,23,31H,1-3,6-7,9-10,16-17,20H2,(H,32,35)(H,33,34,36) | PDB
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| n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207601
(2-(cyclohexanecarboxamido)-N-(4-(naphthalen-2-ylme...)Show SMILES O=C(Nc1nc2ccc(cc2s1)C(=O)NCCCCNCc1ccc2ccccc2c1)C1CCCCC1 Show InChI InChI=1S/C30H34N4O2S/c35-28(32-17-7-6-16-31-20-21-12-13-22-8-4-5-11-24(22)18-21)25-14-15-26-27(19-25)37-30(33-26)34-29(36)23-9-2-1-3-10-23/h4-5,8,11-15,18-19,23,31H,1-3,6-7,9-10,16-17,20H2,(H,32,35)(H,33,34,36) | PDB
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| n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207606
(CHEMBL253163 | N-(2-(naphthalen-2-ylmethylamino)et...)Show SMILES O=C(NCCNCc1ccc2ccccc2c1)c1ccc2nc(NC(=O)c3ccccn3)sc2c1 Show InChI InChI=1S/C27H23N5O2S/c33-25(30-14-13-28-17-18-8-9-19-5-1-2-6-20(19)15-18)21-10-11-22-24(16-21)35-27(31-22)32-26(34)23-7-3-4-12-29-23/h1-12,15-16,28H,13-14,17H2,(H,30,33)(H,31,32,34) | PDB
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| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207605
(2-(2-chloronicotinamido)-N-(2-(naphthalen-2-ylmeth...)Show SMILES Clc1ncccc1C(=O)Nc1nc2ccc(cc2s1)C(=O)NCCNCc1ccc2ccccc2c1 Show InChI InChI=1S/C27H22ClN5O2S/c28-24-21(6-3-11-30-24)26(35)33-27-32-22-10-9-20(15-23(22)36-27)25(34)31-13-12-29-16-17-7-8-18-4-1-2-5-19(18)14-17/h1-11,14-15,29H,12-13,16H2,(H,31,34)(H,32,33,35) | PDB
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Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207634
(CHEMBL252545 | N-(2-(naphthalen-2-ylmethylamino)et...)Show SMILES O=C(NCCNCc1ccc2ccccc2c1)c1ccc2nc(NCc3ccccn3)sc2c1 Show InChI InChI=1S/C27H25N5OS/c33-26(30-14-13-28-17-19-8-9-20-5-1-2-6-21(20)15-19)22-10-11-24-25(16-22)34-27(32-24)31-18-23-7-3-4-12-29-23/h1-12,15-16,28H,13-14,17-18H2,(H,30,33)(H,31,32) | PDB
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Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207639
(2-(4-chlorobenzamido)-N-(2-(naphthalen-2-ylmethyla...)Show SMILES Clc1ccc(cc1)C(=O)Nc1nc2ccc(cc2s1)C(=O)NCCNCc1ccc2ccccc2c1 Show InChI InChI=1S/C28H23ClN4O2S/c29-23-10-7-20(8-11-23)27(35)33-28-32-24-12-9-22(16-25(24)36-28)26(34)31-14-13-30-17-18-5-6-19-3-1-2-4-21(19)15-18/h1-12,15-16,30H,13-14,17H2,(H,31,34)(H,32,33,35) | PDB
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| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207609
(2-amino-N-(2-(naphthalen-2-ylmethylamino)ethyl)ben...)Show InChI InChI=1S/C21H20N4OS/c22-21-25-18-8-7-17(12-19(18)27-21)20(26)24-10-9-23-13-14-5-6-15-3-1-2-4-16(15)11-14/h1-8,11-12,23H,9-10,13H2,(H2,22,25)(H,24,26) | PDB
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| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207634
(CHEMBL252545 | N-(2-(naphthalen-2-ylmethylamino)et...)Show SMILES O=C(NCCNCc1ccc2ccccc2c1)c1ccc2nc(NCc3ccccn3)sc2c1 Show InChI InChI=1S/C27H25N5OS/c33-26(30-14-13-28-17-19-8-9-20-5-1-2-6-21(20)15-19)22-10-11-24-25(16-22)34-27(32-24)31-18-23-7-3-4-12-29-23/h1-12,15-16,28H,13-14,17-18H2,(H,30,33)(H,31,32) | PDB
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Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207609
(2-amino-N-(2-(naphthalen-2-ylmethylamino)ethyl)ben...)Show InChI InChI=1S/C21H20N4OS/c22-21-25-18-8-7-17(12-19(18)27-21)20(26)24-10-9-23-13-14-5-6-15-3-1-2-4-16(15)11-14/h1-8,11-12,23H,9-10,13H2,(H2,22,25)(H,24,26) | PDB
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Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207639
(2-(4-chlorobenzamido)-N-(2-(naphthalen-2-ylmethyla...)Show SMILES Clc1ccc(cc1)C(=O)Nc1nc2ccc(cc2s1)C(=O)NCCNCc1ccc2ccccc2c1 Show InChI InChI=1S/C28H23ClN4O2S/c29-23-10-7-20(8-11-23)27(35)33-28-32-24-12-9-22(16-25(24)36-28)26(34)31-14-13-30-17-18-5-6-19-3-1-2-4-21(19)15-18/h1-12,15-16,30H,13-14,17H2,(H,31,34)(H,32,33,35) | PDB
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Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
Glycylpeptide N-tetradecanoyltransferase
(Candida albicans (Yeast)) | BDBM50207606
(CHEMBL253163 | N-(2-(naphthalen-2-ylmethylamino)et...)Show SMILES O=C(NCCNCc1ccc2ccccc2c1)c1ccc2nc(NC(=O)c3ccccn3)sc2c1 Show InChI InChI=1S/C27H23N5O2S/c33-25(30-14-13-28-17-18-8-9-19-5-1-2-6-20(19)15-18)21-10-11-22-24(16-21)35-27(31-22)32-26(34)23-7-3-4-12-29-23/h1-12,15-16,28H,13-14,17H2,(H,30,33)(H,31,32,34) | PDB
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| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University
Curated by ChEMBL
| Assay Description
Inhibition of Candida albicans N-myristoyltransferse |
Eur J Med Chem 42: 477-86 (2007)
Article DOI: 10.1016/j.ejmech.2006.11.001
BindingDB Entry DOI: 10.7270/Q2RV0ND9 |
More data for this
Ligand-Target Pair | |
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