BindingDB PrimarySearch

Found 1330 hits of ic50 for UniProtKB: P35439
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50073956 (CHEMBL85567 \| {5-Aminomethyl-2-[2-((S)-9-chloro-2,...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Affinity for glycine site of N-methyl-D-aspartate glutamate receptor determined by displacement of tritium labeled selective glycine antagonist [3H]-...				J Med Chem 46: 691-701 (2003) Article DOI: 10.1021/jm020239l BindingDB Entry DOI: 10.7270/Q2G44PP3
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50038171 (7-Chloro-4-hydroxy-3-[3-(thiophen-3-yloxy)-phenyl]...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranes				J Med Chem 37: 1402-5 (1994) BindingDB Entry DOI: 10.7270/Q2DF6Q8C
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50123792 (3-[(4-Aminomethyl-2-carboxymethyl-phenylcarbamoyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Affinity for glycine site of N-methyl-D-aspartate glutamate receptor determined by displacement of tritium labeled selective glycine antagonist [3H]-...				J Med Chem 46: 691-701 (2003) Article DOI: 10.1021/jm020239l BindingDB Entry DOI: 10.7270/Q2G44PP3
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50038168 (7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Urbino Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cor...				J Med Chem 41: 808-20 (1998) Article DOI: 10.1021/jm970416w BindingDB Entry DOI: 10.7270/Q2QZ293M
Università degli Studi di Urbino Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50038168 (7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [3H]-L-689,560 from rat cortical membrane				Bioorg Med Chem Lett 5: 2089-2092 (1995) Article DOI: 10.1016/0960-894X(95)00374-3 BindingDB Entry DOI: 10.7270/Q2HX1CMK
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50038168 (7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description In vitro ability to displace [3H]L-689,560 binding to glycine site on the N-methyl-D-aspartate (NMDA) glutamate receptor 1 from rat cortical membrane...				J Med Chem 40: 754-65 (1997) Article DOI: 10.1021/jm9605492 BindingDB Entry DOI: 10.7270/Q2J67G1J
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50140341 (6-(3-(4-(4-fluorobenzyl)piperidin-1-yl)prop-1-ynyl...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity against NR1A/2B receptor in rat brains by [3H]-ifenprodil displacement.				Bioorg Med Chem Lett 14: 1213-6 (2004) Article DOI: 10.1016/j.bmcl.2003.12.049 BindingDB Entry DOI: 10.7270/Q2057FBV
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50038168 (7-Chloro-4-hydroxy-3-(3-phenoxy-phenyl)-1H-quinoli...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranes				J Med Chem 37: 1402-5 (1994) BindingDB Entry DOI: 10.7270/Q2DF6Q8C
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50041466 (7-Chloro-4-hydroxy-3-[3-(4-methoxymethoxy-benzyl)-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranes				J Med Chem 37: 1402-5 (1994) BindingDB Entry DOI: 10.7270/Q2DF6Q8C
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50041468 (7-Chloro-4-hydroxy-3-(3-thiophen-3-ylmethyl-phenyl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranes				J Med Chem 37: 1402-5 (1994) BindingDB Entry DOI: 10.7270/Q2DF6Q8C
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50123790 (3-{[4-Aminomethyl-2-(1-carboxy-ethyl)-phenylcarbam...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Affinity for glycine site of N-methyl-D-aspartate glutamate receptor determined by displacement of tritium labeled selective glycine antagonist [3H]-...				J Med Chem 46: 691-701 (2003) Article DOI: 10.1021/jm020239l BindingDB Entry DOI: 10.7270/Q2G44PP3
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50091636 (5-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-prop-1-y...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity against NR1A/2B receptor in rat brains by [3H]-ifenprodil displacement.				Bioorg Med Chem Lett 14: 1213-6 (2004) Article DOI: 10.1016/j.bmcl.2003.12.049 BindingDB Entry DOI: 10.7270/Q2057FBV
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50035373 (7-Chloro-2-(4-methoxy-phenyl)-3,5-dihydro-2H-pyraz...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck, Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]-3 binding to the glycine site on the NMDA receptor in Rat cortical slices				J Med Chem 38: 2239-43 (1995) BindingDB Entry DOI: 10.7270/Q2125RQ1
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50140339 (5-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-prop-1-y...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity against NR1A/2B receptor in rat brains by [3H]-ifenprodil displacement.				Bioorg Med Chem Lett 14: 1213-6 (2004) Article DOI: 10.1016/j.bmcl.2003.12.049 BindingDB Entry DOI: 10.7270/Q2057FBV
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005075 ((2R,4S)-5,7-Dichloro-4-(3-phenyl-ureido)-1,2,3,4-t...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranes				J Med Chem 37: 1402-5 (1994) BindingDB Entry DOI: 10.7270/Q2DF6Q8C
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50041464 (3-(3-Benzyl-phenyl)-7-chloro-4-hydroxy-1H-quinolin...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranes				J Med Chem 37: 1402-5 (1994) BindingDB Entry DOI: 10.7270/Q2DF6Q8C
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50041465 (7-Chloro-4-hydroxy-3-[3-(4-methoxy-benzyl)-phenyl]...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of the binding of [3H]-L-689,560 ([3H]-4) to the strychnine-insensitive glycine site on rat brain membranes				J Med Chem 37: 1402-5 (1994) BindingDB Entry DOI: 10.7270/Q2DF6Q8C
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50056605 (7-Chloro-6-methyl-5-nitro-1,4-dihydro-quinoxaline-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys Inc. Curated by ChEMBL					Assay Description Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...				J Med Chem 40: 730-8 (1997) Article DOI: 10.1021/jm960654b BindingDB Entry DOI: 10.7270/Q2NZ86RJ
CoCensys Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005072 (5,7-Dichloro-4-(3-p-tolyl-ureido)-1,2,3,4-tetrahyd...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.				J Med Chem 35: 1954-68 (1992) BindingDB Entry DOI: 10.7270/Q2T72GCZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT)	BDBM50425996 (CHEMBL2314718) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT)	BDBM50426000 (CHEMBL2311573) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50038161 (6,7-Dichloro-3-hydroxy-5-nitro-3,4-dihydro-1H-quin...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys Inc. Curated by ChEMBL					Assay Description Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...				J Med Chem 40: 730-8 (1997) Article DOI: 10.1021/jm960654b BindingDB Entry DOI: 10.7270/Q2NZ86RJ
CoCensys Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005055 (7-Chloro-5-iodo-4-(3-phenyl-ureido)-1,2,3,4-tetrah...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.				J Med Chem 35: 1954-68 (1992) BindingDB Entry DOI: 10.7270/Q2T72GCZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005044 ((2R,4S)-5,7-Dichloro-4-(2-oxo-3-phenyl-imidazolidi...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.				J Med Chem 35: 1954-68 (1992) BindingDB Entry DOI: 10.7270/Q2T72GCZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005044 ((2R,4S)-5,7-Dichloro-4-(2-oxo-3-phenyl-imidazolidi...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Urbino Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cor...				J Med Chem 41: 808-20 (1998) Article DOI: 10.1021/jm970416w BindingDB Entry DOI: 10.7270/Q2QZ293M
Università degli Studi di Urbino Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50069471 (CHEMBL357190 \| N-(7-Bromo-2,3-dioxo-1,2,3,4-tetrah...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description In vitro binding assay for the displacement of [3H]MDL-105519 from the glycine-site of NMDA receptors				Bioorg Med Chem Lett 8: 493-8 (1999) BindingDB Entry DOI: 10.7270/Q29G5NBG
Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50052635 (5,6,7-Trichloro-1H-quinoline-2,3,4-trione 3-oxime ...) Show SMILES Oc1c(N=O)c(=O)[nH]c2cc(Cl)c(Cl)c(Cl)c12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]- DCKA binding to NMDA receptor of rat brain membranes				J Med Chem 39: 3248-55 (1996) Article DOI: 10.1021/jm960214k BindingDB Entry DOI: 10.7270/Q2QC02KC
CoCensys Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005086 (5,7-Dichloro-4-(3-o-tolyl-ureido)-1,2,3,4-tetrahyd...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.				J Med Chem 35: 1954-68 (1992) BindingDB Entry DOI: 10.7270/Q2T72GCZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005075 ((2R,4S)-5,7-Dichloro-4-(3-phenyl-ureido)-1,2,3,4-t...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.				J Med Chem 35: 1954-68 (1992) BindingDB Entry DOI: 10.7270/Q2T72GCZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50123796 (3-[(2-Carboxymethyl-phenylcarbamoyl)-methyl]-7-chl...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					Assay Description Affinity for glycine site of N-methyl-D-aspartate glutamate receptor determined by displacement of tritium labeled selective glycine antagonist [3H]-...				J Med Chem 46: 691-701 (2003) Article DOI: 10.1021/jm020239l BindingDB Entry DOI: 10.7270/Q2G44PP3
Sumitomo Pharmaceuticals Co., Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005075 ((2R,4S)-5,7-Dichloro-4-(3-phenyl-ureido)-1,2,3,4-t...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Urbino Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-glycine to N-methyl-D-aspartate glutamate receptor 1 from crude synaptic membranes prepared from adult rat cerebral cor...				J Med Chem 41: 808-20 (1998) Article DOI: 10.1021/jm970416w BindingDB Entry DOI: 10.7270/Q2QZ293M
Università degli Studi di Urbino Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50066544 (4-[2-(5-Phenyl-pentylamino)-ethyl]-phenol \| CHEMBL...) Show SMILES Oc1ccc(CCNCCCCCc2ccccc2)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
University of Oregon Curated by ChEMBL					Assay Description Functional antagonism by electrical assays in Xenopus oocytes expressing the 1A/2B NMDA receptor				J Med Chem 41: 3499-506 (1998) Article DOI: 10.1021/jm980235+ BindingDB Entry DOI: 10.7270/Q29Z95MM
University of Oregon Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT)	BDBM50426009 (CHEMBL2314938) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50056596 (7-Bromo-6-methyl-5-nitro-1,4-dihydro-quinoxaline-2...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys Inc. Curated by ChEMBL					Assay Description Potency for the N-methyl-D-aspartate glutamate receptor 1 glycine site by displacement of [3H]5,7-dichlorokynurenic acid (DCKA) binding in rat brain ...				J Med Chem 40: 730-8 (1997) Article DOI: 10.1021/jm960654b BindingDB Entry DOI: 10.7270/Q2NZ86RJ
CoCensys Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50080029 (4-((1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Messina Curated by ChEMBL					Assay Description Inhibition of rat NMDA receptor NR1C/NR2B subunit expressed in Xenopus laevis oocytes after 2 days by two-electrode voltage-clamp electrophysiologica...				J Med Chem 55: 10532-9 (2012) Article DOI: 10.1021/jm301508d BindingDB Entry DOI: 10.7270/Q2RN3919
Universit£ di Messina Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50080029 (4-((1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
University of Oregon Curated by ChEMBL					Assay Description Antagonistic activity against N-methyl-D-aspartate glutamate receptor 1/2B.				J Med Chem 42: 3412-20 (1999) Article DOI: 10.1021/jm990199u BindingDB Entry DOI: 10.7270/Q2RR1XFD
University of Oregon Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50080029 (4-((1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
University of Oregon Curated by ChEMBL					Assay Description Antagonist activity against rat 1A/2B subtype of N-methyl-D-aspartate(NMDA) receptor in xenopus oocytes.				Bioorg Med Chem Lett 9: 1619-24 (1999) BindingDB Entry DOI: 10.7270/Q29022ZJ
University of Oregon Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50140333 (5-{3-[4-(4-Fluoro-benzyl)-piperidin-1-yl]-prop-1-y...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity against NR1A/2B receptor in rat brains by [3H]-ifenprodil displacement.				Bioorg Med Chem Lett 14: 1213-6 (2004) Article DOI: 10.1016/j.bmcl.2003.12.049 BindingDB Entry DOI: 10.7270/Q2057FBV
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2A (Rattus norvegicus (Rat)-RAT)	BDBM50316373 (Argiotoxin-636 \| CHEMBL1098240) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Inhibition of rat GluN1/2A receptor expressed in Xenopus laevis oocyte assessed as glutamate and glycine-induced current at holding potentials from -...				J Med Chem 56: 1171-81 (2013) Article DOI: 10.1021/jm301602d BindingDB Entry DOI: 10.7270/Q2S46T9C
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50069458 (CHEMBL147895 \| N-(7-Bromo-2,3-dioxo-1,2,3,4-tetrah...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description In vitro binding assay for the displacement of [3H]MDL-105519 from the glycine-site of NMDA receptors				Bioorg Med Chem Lett 8: 493-8 (1999) BindingDB Entry DOI: 10.7270/Q29G5NBG
Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50069482 (CHEMBL357916 \| N-(7-Bromo-2,3-dioxo-1,2,3,4-tetrah...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description In vitro binding assay for the displacement of [3H]MDL-105519 from the glycine-site of NMDA receptors				Bioorg Med Chem Lett 8: 493-8 (1999) BindingDB Entry DOI: 10.7270/Q29G5NBG
Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005047 (7-Chloro-5-iodo-4-phenylacetylamino-1,2,3,4-tetrah...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.				J Med Chem 35: 1954-68 (1992) BindingDB Entry DOI: 10.7270/Q2T72GCZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50069459 (CHEMBL413125 \| Thiophene-3-carboxylic acid (7-brom...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description In vitro binding assay for the displacement of [3H]MDL-105519 from the glycine-site of NMDA receptors				Bioorg Med Chem Lett 8: 493-8 (1999) BindingDB Entry DOI: 10.7270/Q29G5NBG
Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50069483 (CHEMBL356281 \| N-(7-Bromo-2,3-dioxo-1,2,3,4-tetrah...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description In vitro binding assay for the displacement of [3H]MDL-105519 from the glycine-site of NMDA receptors				Bioorg Med Chem Lett 8: 493-8 (1999) BindingDB Entry DOI: 10.7270/Q29G5NBG
Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50069495 (CHEMBL147894 \| N-(7-Chloro-2,3-dioxo-1,2,3,4-tetra...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description In vitro binding assay for the displacement of [3H]MDL-105519 from the glycine-site of NMDA receptors				Bioorg Med Chem Lett 8: 493-8 (1999) BindingDB Entry DOI: 10.7270/Q29G5NBG
Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50069465 (CHEMBL343863 \| Thiophene-2-carboxylic acid (7-brom...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description In vitro binding assay for the displacement of [3H]MDL-105519 from the glycine-site of NMDA receptors				Bioorg Med Chem Lett 8: 493-8 (1999) BindingDB Entry DOI: 10.7270/Q29G5NBG
Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1/2B (Rattus norvegicus (Rat)-RAT)	BDBM50369783 (CHEMBL1203902) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
CoCensys, Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Xenopus oocytes expressing rat N-Methyl-D-aspartate (NR1A/2B) Receptor subtype.				J Med Chem 43: 984-94 (2000) BindingDB Entry DOI: 10.7270/Q20G3KVT
CoCensys, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005053 ((-) 5,7-Dichloro-4-phenylacetylamino-1,2,3,4-tetra...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.				J Med Chem 35: 1954-68 (1992) BindingDB Entry DOI: 10.7270/Q2T72GCZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005081 (5,7-Dichloro-4-(3-naphthalen-1-yl-ureido)-1,2,3,4-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]- glycine binding to N-methyl-D-aspartate glutamate receptor from rat cortical membranes				J Med Chem 35: 1954-68 (1992) BindingDB Entry DOI: 10.7270/Q2T72GCZ
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50005053 ((-) 5,7-Dichloro-4-phenylacetylamino-1,2,3,4-tetra...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]- glycine binding to NMDA receptor from rat cortical membranes.				J Med Chem 35: 1954-68 (1992) BindingDB Entry DOI: 10.7270/Q2T72GCZ
					More data for this Ligand-Target Pair

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