Compile Data Set for Download or QSAR

Found 3 hits of ic50 for UniProtKB: P43253   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostacyclin receptor (RAT)	BDBM50191133 (CHEMBL439357 | sodium (R)-2-(3-((2-(4,5-diphenylox...) Show SMILES [O-]C(=O)COc1cccc(CN2CCC[C@@H]2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 Show InChI InChI=1S/C28H26N2O4/c31-25(32)19-33-23-14-7-9-20(17-23)18-30-16-8-15-24(30)28-29-26(21-10-3-1-4-11-21)27(34-28)22-12-5-2-6-13-22/h1-7,9-14,17,24H,8,15-16,18-19H2,(H,31,32)/p-1/t24-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at rat PGI2 receptor assessed as inhibition of ADP-induced platelet aggregation				Bioorg Med Chem Lett 16: 4861-4 (2006) Article DOI: 10.1016/j.bmcl.2006.06.076 BindingDB Entry DOI: 10.7270/Q2R49QD9
					More data for this Ligand-Target Pair
Prostacyclin receptor (RAT)	BDBM50136234 (CHEMBL132589 | FR-181157 | Sodium; {3-[(R)-2-(4,5-...) Show SMILES [O-]C(=O)COc1cccc(CC2CCCC=C2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 |c:15| Show InChI InChI=1S/C30H27NO4/c32-27(33)20-34-25-16-9-10-21(19-25)18-24-15-7-8-17-26(24)30-31-28(22-11-3-1-4-12-22)29(35-30)23-13-5-2-6-14-23/h1-6,9-14,16-17,19,24H,7-8,15,18,20H2,(H,32,33)/p-1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at rat PGI2 receptor assessed as inhibition of ADP-induced platelet aggregation				Bioorg Med Chem Lett 16: 4861-4 (2006) Article DOI: 10.1016/j.bmcl.2006.06.076 BindingDB Entry DOI: 10.7270/Q2R49QD9
					More data for this Ligand-Target Pair
Prostacyclin receptor (RAT)	BDBM50191132 (CHEMBL438092 | sodium (S)-2-(3-((2-(4,5-diphenylox...) Show SMILES [O-]C(=O)COc1cccc(CN2CCC[C@H]2c2nc(c(o2)-c2ccccc2)-c2ccccc2)c1 Show InChI InChI=1S/C28H26N2O4/c31-25(32)19-33-23-14-7-9-20(17-23)18-30-16-8-15-24(30)28-29-26(21-10-3-1-4-11-21)27(34-28)22-12-5-2-6-13-22/h1-7,9-14,17,24H,8,15-16,18-19H2,(H,31,32)/p-1/t24-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Fujisawa Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Agonist activity at rat PGI2 receptor assessed as inhibition of ADP-induced platelet aggregation				Bioorg Med Chem Lett 16: 4861-4 (2006) Article DOI: 10.1016/j.bmcl.2006.06.076 BindingDB Entry DOI: 10.7270/Q2R49QD9
					More data for this Ligand-Target Pair