BindingDB PrimarySearch

Found 11 hits of ic50 for UniProtKB: P11021
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Endoplasmic reticulum chaperone BiP (Homo sapiens (Human))	BDBM50088528 (CHEMBL3576921) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of California San Diego Curated by ChEMBL					Assay Description Inhibition of 2-deoxyglucose-induced GRP78 (unknown origin) expression transfected in human HT1080 cells by luciferase reporter gene assay				J Nat Prod 78: 562-75 (2015) Article DOI: 10.1021/np500757w BindingDB Entry DOI: 10.7270/Q2HQ41NZ
University of California San Diego Curated by ChEMBL					More data for this Ligand-Target Pair
Endoplasmic reticulum chaperone BiP (Homo sapiens (Human))	BDBM32378 (adenosine-derived inhibitor (Grp78), 13 \| adenosin...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...				Bioorg Med Chem Lett 29: 1689-1693 (2019) Article DOI: 10.1016/j.bmcl.2019.05.041 BindingDB Entry DOI: 10.7270/Q23F4T1X
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Endoplasmic reticulum chaperone BiP (Homo sapiens (Human))	BDBM31712 (HEXACHLOROPHENE \| Hexach-lorophene \| MLS000028433 ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...				Bioorg Med Chem Lett 29: 1689-1693 (2019) Article DOI: 10.1016/j.bmcl.2019.05.041 BindingDB Entry DOI: 10.7270/Q23F4T1X
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair
Endoplasmic reticulum chaperone BiP (Homo sapiens (Human))	BDBM31712 (HEXACHLOROPHENE \| Hexach-lorophene \| MLS000028433 ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...				Bioorg Med Chem Lett 29: 1689-1693 (2019) Article DOI: 10.1016/j.bmcl.2019.05.041 BindingDB Entry DOI: 10.7270/Q23F4T1X
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair
Endoplasmic reticulum chaperone BiP (Homo sapiens (Human))	BDBM31712 (HEXACHLOROPHENE \| Hexach-lorophene \| MLS000028433 ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...				Bioorg Med Chem Lett 29: 1689-1693 (2019) Article DOI: 10.1016/j.bmcl.2019.05.041 BindingDB Entry DOI: 10.7270/Q23F4T1X
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair
Endoplasmic reticulum chaperone BiP (Homo sapiens (Human))	BDBM50303912 (2,2'-methylenebis(4-chlorophenol) \| 3,3'-dichloro-...) Show SMILES Oc1ccc(Cl)cc1Cc1cc(Cl)ccc1O Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...				Bioorg Med Chem Lett 29: 1689-1693 (2019) Article DOI: 10.1016/j.bmcl.2019.05.041 BindingDB Entry DOI: 10.7270/Q23F4T1X
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair
Endoplasmic reticulum chaperone BiP (Homo sapiens (Human))	BDBM50522653 (2-(2-Hydroxybenzyl)Phenol \| CHEBI:34207 \| CHEMBL14...) Show SMILES Oc1ccccc1Cc1ccccc1O Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...				Bioorg Med Chem Lett 29: 1689-1693 (2019) Article DOI: 10.1016/j.bmcl.2019.05.041 BindingDB Entry DOI: 10.7270/Q23F4T1X
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair
Endoplasmic reticulum chaperone BiP (Homo sapiens (Human))	BDBM50522652 (CHEMBL3182523) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...				Bioorg Med Chem Lett 29: 1689-1693 (2019) Article DOI: 10.1016/j.bmcl.2019.05.041 BindingDB Entry DOI: 10.7270/Q23F4T1X
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair
Endoplasmic reticulum chaperone BiP (Homo sapiens (Human))	BDBM8726 (5-chloro-2-(2,4-dichlorophenoxy)phenol \| CHEMBL849...) Show SMILES Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...				Bioorg Med Chem Lett 29: 1689-1693 (2019) Article DOI: 10.1016/j.bmcl.2019.05.041 BindingDB Entry DOI: 10.7270/Q23F4T1X
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair
Endoplasmic reticulum chaperone BiP (Homo sapiens (Human))	BDBM430653 (Oxyclozanide) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...				Bioorg Med Chem Lett 29: 1689-1693 (2019) Article DOI: 10.1016/j.bmcl.2019.05.041 BindingDB Entry DOI: 10.7270/Q23F4T1X
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair
Endoplasmic reticulum chaperone BiP (Homo sapiens (Human))	BDBM50522651 (CHEMBL460648) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by ChEMBL					Assay Description Inhibition of GRP78 (26 to 636 residues) (unknown origin) expressed in Escherichia coli BL21 DE3 cells pre-incubated for 10 mins before FITC-NRLLLTG ...				Bioorg Med Chem Lett 29: 1689-1693 (2019) Article DOI: 10.1016/j.bmcl.2019.05.041 BindingDB Entry DOI: 10.7270/Q23F4T1X
University of Arizona Curated by ChEMBL					More data for this Ligand-Target Pair