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Compile Data Set for Download or QSAR

Found 27 hits of ic50 for UniProtKB: P21183   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517037
PNG
(CHEMBL4463994)
Show SMILES CCC(CO)NCc1nc2c(OCC3CCCCC3)cccc2[nH]1
Show InChI InChI=1S/C19H29N3O2/c1-2-15(12-23)20-11-18-21-16-9-6-10-17(19(16)22-18)24-13-14-7-4-3-5-8-14/h6,9-10,14-15,20,23H,2-5,7-8,11-13H2,1H3,(H,21,22)
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n/an/a 3.50E+3n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517049
PNG
(CHEMBL4586328)
Show SMILES OCC(CC1CCCCC1)NCc1nc2c(OCC3CCCCC3)cccc2[nH]1
Show InChI InChI=1S/C24H37N3O2/c28-16-20(14-18-8-3-1-4-9-18)25-15-23-26-21-12-7-13-22(24(21)27-23)29-17-19-10-5-2-6-11-19/h7,12-13,18-20,25,28H,1-6,8-11,14-17H2,(H,26,27)
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n/an/a 5.00E+3n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517038
PNG
(CHEMBL4581146)
Show SMILES CCCC(CO)NCc1nc2c(OCC3CCCCC3)cccc2[nH]1
Show InChI InChI=1S/C20H31N3O2/c1-2-7-16(13-24)21-12-19-22-17-10-6-11-18(20(17)23-19)25-14-15-8-4-3-5-9-15/h6,10-11,15-16,21,24H,2-5,7-9,12-14H2,1H3,(H,22,23)
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n/an/a 7.50E+3n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50242276
PNG
(CHEMBL486626 | Sophoricoside)
Show SMILES OC[C@H]1O[C@@H](Oc2ccc(cc2)-c2coc3cc(O)cc(O)c3c2=O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Show InChI InChI=1S/C21H20O10/c22-7-15-18(26)19(27)20(28)21(31-15)30-11-3-1-9(2-4-11)12-8-29-14-6-10(23)5-13(24)16(14)17(12)25/h1-6,8,15,18-24,26-28H,7H2/t15-,18-,19+,20-,21-/m1/s1
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n/an/a 1.06E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517040
PNG
(CHEMBL4562876)
Show SMILES OCC(Cc1ccccc1)NCc1nc2c(OCC3CCCCC3)cccc2[nH]1
Show InChI InChI=1S/C24H31N3O2/c28-16-20(14-18-8-3-1-4-9-18)25-15-23-26-21-12-7-13-22(24(21)27-23)29-17-19-10-5-2-6-11-19/h1,3-4,7-9,12-13,19-20,25,28H,2,5-6,10-11,14-17H2,(H,26,27)
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n/an/a 1.20E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517045
PNG
(CHEMBL4445471)
Show SMILES OCCN(Cc1nc2c(OCC3CCCCC3)cccc2[nH]1)Cc1ccc(Cl)cc1
Show InChI InChI=1S/C24H30ClN3O2/c25-20-11-9-18(10-12-20)15-28(13-14-29)16-23-26-21-7-4-8-22(24(21)27-23)30-17-19-5-2-1-3-6-19/h4,7-12,19,29H,1-3,5-6,13-17H2,(H,26,27)
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n/an/a 1.30E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517046
PNG
(CHEMBL4438982)
Show SMILES COc1ccc(CN(CCO)Cc2nc3c(OCC4CCCCC4)cccc3[nH]2)cc1
Show InChI InChI=1S/C25H33N3O3/c1-30-21-12-10-19(11-13-21)16-28(14-15-29)17-24-26-22-8-5-9-23(25(22)27-24)31-18-20-6-3-2-4-7-20/h5,8-13,20,29H,2-4,6-7,14-18H2,1H3,(H,26,27)
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n/an/a 1.90E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517052
PNG
(CHEMBL4534125)
Show SMILES OCC(NCc1nc2c(OCC3CCCCC3)cccc2[nH]1)c1ccccc1
Show InChI InChI=1S/C23H29N3O2/c27-15-20(18-10-5-2-6-11-18)24-14-22-25-19-12-7-13-21(23(19)26-22)28-16-17-8-3-1-4-9-17/h2,5-7,10-13,17,20,24,27H,1,3-4,8-9,14-16H2,(H,25,26)
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n/an/a 2.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517041
PNG
(CHEMBL4459407)
Show SMILES CCCN(CCO)Cc1nc2c(OCC3CCCCC3)cccc2[nH]1
Show InChI InChI=1S/C20H31N3O2/c1-2-11-23(12-13-24)14-19-21-17-9-6-10-18(20(17)22-19)25-15-16-7-4-3-5-8-16/h6,9-10,16,24H,2-5,7-8,11-15H2,1H3,(H,21,22)
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n/an/a 2.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517036
PNG
(CHEMBL4475617)
Show SMILES OCCNCc1nc2c(OCC3CCCCC3)cccc2[nH]1
Show InChI InChI=1S/C17H25N3O2/c21-10-9-18-11-16-19-14-7-4-8-15(17(14)20-16)22-12-13-5-2-1-3-6-13/h4,7-8,13,18,21H,1-3,5-6,9-12H2,(H,19,20)
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n/an/a 2.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517044
PNG
(CHEMBL4572156)
Show SMILES OCCN(CC1CCCCC1)Cc1nc2c(OCC3CCCCC3)cccc2[nH]1
Show InChI InChI=1S/C24H37N3O2/c28-15-14-27(16-19-8-3-1-4-9-19)17-23-25-21-12-7-13-22(24(21)26-23)29-18-20-10-5-2-6-11-20/h7,12-13,19-20,28H,1-6,8-11,14-18H2,(H,25,26)
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n/an/a 2.10E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517054
PNG
(CHEMBL4532376)
Show SMILES OCCC(NCc1nc2c(OCC3CCCCC3)cccc2[nH]1)c1ccccc1
Show InChI InChI=1S/C24H31N3O2/c28-15-14-20(19-10-5-2-6-11-19)25-16-23-26-21-12-7-13-22(24(21)27-23)29-17-18-8-3-1-4-9-18/h2,5-7,10-13,18,20,25,28H,1,3-4,8-9,14-17H2,(H,26,27)
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Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517050
PNG
(CHEMBL4572499)
Show SMILES OCCN(Cc1nc2c(OCC3CCCCC3)cccc2[nH]1)Cc1ccccc1
Show InChI InChI=1S/C24H31N3O2/c28-15-14-27(16-19-8-3-1-4-9-19)17-23-25-21-12-7-13-22(24(21)26-23)29-18-20-10-5-2-6-11-20/h1,3-4,7-9,12-13,20,28H,2,5-6,10-11,14-18H2,(H,25,26)
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n/an/a 2.50E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50354850
PNG
(BUDESONIDE | US10869929, Compound Budesonide | US1...)
Show SMILES CCCC1O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@@]2(O1)C(=O)CO |r,c:15,t:11|
Show InChI InChI=1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21?,22+,23-,24-,25+/m0/s1
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n/an/a 2.62E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517039
PNG
(CHEMBL4530753)
Show SMILES CC(C)(CO)NCc1nc2c(OCC3CCCCC3)cccc2[nH]1
Show InChI InChI=1S/C19H29N3O2/c1-19(2,13-23)20-11-17-21-15-9-6-10-16(18(15)22-17)24-12-14-7-4-3-5-8-14/h6,9-10,14,20,23H,3-5,7-8,11-13H2,1-2H3,(H,21,22)
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n/an/a 2.75E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517033
PNG
(CHEMBL4442984)
Show SMILES OCCCNCc1nc2c(OCC3CCCCC3)cccc2[nH]1
Show InChI InChI=1S/C18H27N3O2/c22-11-5-10-19-12-17-20-15-8-4-9-16(18(15)21-17)23-13-14-6-2-1-3-7-14/h4,8-9,14,19,22H,1-3,5-7,10-13H2,(H,20,21)
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n/an/a 2.85E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517057
PNG
(CHEMBL4469649)
Show SMILES COc1ccc(NCc2nc3c(OCC4CCCCC4)cccc3[nH]2)cc1
Show InChI InChI=1S/C22H27N3O2/c1-26-18-12-10-17(11-13-18)23-14-21-24-19-8-5-9-20(22(19)25-21)27-15-16-6-3-2-4-7-16/h5,8-13,16,23H,2-4,6-7,14-15H2,1H3,(H,24,25)
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Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517056
PNG
(CHEMBL4513551)
Show SMILES OCCN(Cc1nc2c(OCC3CCCCC3)cccc2[nH]1)Cc1ccncc1
Show InChI InChI=1S/C23H30N4O2/c28-14-13-27(15-18-9-11-24-12-10-18)16-22-25-20-7-4-8-21(23(20)26-22)29-17-19-5-2-1-3-6-19/h4,7-12,19,28H,1-3,5-6,13-17H2,(H,25,26)
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Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517055
PNG
(CHEMBL4577331)
Show SMILES CN(CCO)Cc1nc2c(OCC3CCCCC3)cccc2[nH]1
Show InChI InChI=1S/C18H27N3O2/c1-21(10-11-22)12-17-19-15-8-5-9-16(18(15)20-17)23-13-14-6-3-2-4-7-14/h5,8-9,14,22H,2-4,6-7,10-13H2,1H3,(H,19,20)
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Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517053
PNG
(CHEMBL4440415)
Show SMILES OCCCCCNCc1nc2c(OCC3CCCCC3)cccc2[nH]1
Show InChI InChI=1S/C20H31N3O2/c24-13-6-2-5-12-21-14-19-22-17-10-7-11-18(20(17)23-19)25-15-16-8-3-1-4-9-16/h7,10-11,16,21,24H,1-6,8-9,12-15H2,(H,22,23)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517051
PNG
(CHEMBL4567563)
Show SMILES COc1ccc(CNCc2nc3c(OCC4CCCCC4)cccc3[nH]2)cc1
Show InChI InChI=1S/C23H29N3O2/c1-27-19-12-10-17(11-13-19)14-24-15-22-25-20-8-5-9-21(23(20)26-22)28-16-18-6-3-2-4-7-18/h5,8-13,18,24H,2-4,6-7,14-16H2,1H3,(H,25,26)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517048
PNG
(CHEMBL4463959)
Show SMILES OCCCCNCc1nc2c(OCC3CCCCC3)cccc2[nH]1
Show InChI InChI=1S/C19H29N3O2/c23-12-5-4-11-20-13-18-21-16-9-6-10-17(19(16)22-18)24-14-15-7-2-1-3-8-15/h6,9-10,15,20,23H,1-5,7-8,11-14H2,(H,21,22)
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n/an/a 3.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517047
PNG
(CHEMBL4589768)
Show SMILES C(Nc1ccccc1)c1nc2c(OCC3CCCCC3)cccc2[nH]1
Show InChI InChI=1S/C21H25N3O/c1-3-8-16(9-4-1)15-25-19-13-7-12-18-21(19)24-20(23-18)14-22-17-10-5-2-6-11-17/h2,5-7,10-13,16,22H,1,3-4,8-9,14-15H2,(H,23,24)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517043
PNG
(CHEMBL4464998)
Show SMILES OCCN(Cc1nc2c(OCC3CCCCC3)cccc2[nH]1)C1CCCCC1
Show InChI InChI=1S/C23H35N3O2/c27-15-14-26(19-10-5-2-6-11-19)16-22-24-20-12-7-13-21(23(20)25-22)28-17-18-8-3-1-4-9-18/h7,12-13,18-19,27H,1-6,8-11,14-17H2,(H,24,25)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517042
PNG
(CHEMBL4556260)
Show SMILES CC(C)N(CCO)Cc1nc2c(OCC3CCCCC3)cccc2[nH]1
Show InChI InChI=1S/C20H31N3O2/c1-15(2)23(11-12-24)13-19-21-17-9-6-10-18(20(17)22-19)25-14-16-7-4-3-5-8-16/h6,9-10,15-16,24H,3-5,7-8,11-14H2,1-2H3,(H,21,22)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517035
PNG
(CHEMBL4581975)
Show SMILES C(NCc1ccccc1)c1nc2c(OCC3CCCCC3)cccc2[nH]1
Show InChI InChI=1S/C22H27N3O/c1-3-8-17(9-4-1)14-23-15-21-24-19-12-7-13-20(22(19)25-21)26-16-18-10-5-2-6-11-18/h1,3-4,7-9,12-13,18,23H,2,5-6,10-11,14-16H2,(H,24,25)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair
Interleukin-5 receptor subunit alpha


(Mus musculus)
BDBM50517034
PNG
(CHEMBL4533564)
Show SMILES CCN(CCO)Cc1nc2c(OCC3CCCCC3)cccc2[nH]1
Show InChI InChI=1S/C19H29N3O2/c1-2-22(11-12-23)13-18-20-16-9-6-10-17(19(16)21-18)24-14-15-7-4-3-5-8-15/h6,9-10,15,23H,2-5,7-8,11-14H2,1H3,(H,20,21)
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n/an/a>3.00E+4n/an/an/an/an/an/a



Chungnam National University

Curated by ChEMBL


Assay Description
Inhibition of IL-5 receptor in mouse pro-B Y16 cells assessed as decrease in mIL-5 dependent cell proliferation after 48 hrs in presence of 3 units/m...


Eur J Med Chem 181: (2019)


Article DOI: 10.1016/j.ejmech.2019.111574
BindingDB Entry DOI: 10.7270/Q2P272G8
More data for this
Ligand-Target Pair