Found 255 hits of ic50 for UniProtKB: P08104 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50223720
(CHEMBL332257)Show SMILES CCCCCC(CCCCC)c1nc(c[nH]1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C26H34N2/c1-3-5-8-14-24(15-9-6-4-2)26-27-20-25(28-26)23-18-16-22(17-19-23)21-12-10-7-11-13-21/h7,10-13,16-20,24H,3-6,8-9,14-15H2,1-2H3,(H,27,28) | PDB
UniProtKB/SwissProt
GoogleScholar
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| CHEMBL
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PC sid
UniChem
Similars
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| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour
Curated by ChEMBL
| Assay Description
Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain |
Bioorg Med Chem Lett 14: 3521-3 (2004)
BindingDB Entry DOI: 10.7270/Q2474D2N |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50367676
(CHEMBL4160662)Show SMILES Cn1cc(ccc1=O)-c1ccc(cc1)N([C@H]1CC[C@@H](CC1)Nc1ccc(cn1)C#N)C(=O)NCc1ccccc1 |r,wU:15.16,wD:18.23,(17.35,-24.38,;18.11,-25.71,;19.66,-25.71,;20.43,-27.05,;19.66,-28.38,;18.11,-28.38,;17.35,-27.05,;15.8,-27.05,;21.97,-27.05,;22.74,-28.38,;24.28,-28.38,;25.05,-27.05,;24.28,-25.71,;22.74,-25.71,;26.6,-27.05,;27.37,-25.71,;26.6,-24.38,;27.37,-23.04,;28.91,-23.04,;29.68,-24.38,;28.91,-25.71,;29.68,-21.71,;31.22,-21.71,;31.99,-20.37,;33.54,-20.37,;34.3,-21.71,;33.54,-23.04,;31.99,-23.04,;35.85,-21.71,;37.39,-21.71,;27.37,-28.38,;26.6,-29.71,;28.91,-28.38,;29.68,-29.71,;31.22,-29.71,;31.99,-28.38,;33.54,-28.38,;34.3,-29.71,;33.54,-31.05,;31.99,-31.05,)| Show InChI InChI=1S/C32H32N6O2/c1-37-22-26(10-18-31(37)39)25-8-13-28(14-9-25)38(32(40)35-20-23-5-3-2-4-6-23)29-15-11-27(12-16-29)36-30-17-7-24(19-33)21-34-30/h2-10,13-14,17-18,21-22,27,29H,11-12,15-16,20H2,1H3,(H,34,36)(H,35,40)/t27-,29- | PDB
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Takeda Pharmaceutical Company Limited
Curated by ChEMBL
| Assay Description
Inhibition of N-terminal FLAG-tagged human full-length CDK13 (1 to 1512 residues)/N-terminal His-tagged CycK (1 to 580 residues) expressed in Sf9 cel... |
J Med Chem 61: 7710-7728 (2018)
Article DOI: 10.1021/acs.jmedchem.8b00683
BindingDB Entry DOI: 10.7270/Q2HX1G6F |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50597426
(CHEMBL5169449)Show SMILES NCCSc1nc(NCc2ccc(cc2)-c2ccccn2)c2[nH]nc(C3CCC3)c2n1 | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02184
BindingDB Entry DOI: 10.7270/Q26114CS |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50223731
(CHEMBL118603)Show InChI InChI=1S/C21H24N2/c1-2-3-4-8-11-21-22-16-20(23-21)19-14-12-18(13-15-19)17-9-6-5-7-10-17/h5-7,9-10,12-16H,2-4,8,11H2,1H3,(H,22,23) | PDB
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| CHEMBL
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PC sid
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| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour
Curated by ChEMBL
| Assay Description
Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain |
Bioorg Med Chem Lett 14: 3521-3 (2004)
BindingDB Entry DOI: 10.7270/Q2474D2N |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50223721
(CHEMBL331513)Show SMILES C(CC1CCCCC1)Cc1nc(c[nH]1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C24H28N2/c1-3-8-19(9-4-1)10-7-13-24-25-18-23(26-24)22-16-14-21(15-17-22)20-11-5-2-6-12-20/h2,5-6,11-12,14-19H,1,3-4,7-10,13H2,(H,25,26) | PDB
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| CHEMBL
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| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour
Curated by ChEMBL
| Assay Description
Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain |
Bioorg Med Chem Lett 14: 3521-3 (2004)
BindingDB Entry DOI: 10.7270/Q2474D2N |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50139171
(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)Show SMILES CCc1cnn2c(NCc3ccc[n+]([O-])c3)cc(nc12)N1CCCC[C@H]1CCO |r| Show InChI InChI=1S/C21H28N6O2/c1-2-17-14-23-27-19(22-13-16-6-5-9-25(29)15-16)12-20(24-21(17)27)26-10-4-3-7-18(26)8-11-28/h5-6,9,12,14-15,18,22,28H,2-4,7-8,10-11,13H2,1H3/t18-/m0/s1 | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02184
BindingDB Entry DOI: 10.7270/Q26114CS |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50597425
(CHEMBL5194202)Show SMILES NCCSc1nc(NCc2ccc(cc2)-n2cccn2)c2[nH]nc(C3CCC3)c2n1 | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02184
BindingDB Entry DOI: 10.7270/Q26114CS |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50597424
(CHEMBL5187378)Show SMILES CC(C)c1n[nH]c2c(NCc3ccc(cc3)-c3cnccn3)nc(SCCN)nc12 | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02184
BindingDB Entry DOI: 10.7270/Q26114CS |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50223726
(CHEMBL117331)Show InChI InChI=1S/C20H29FN2/c1-3-5-7-9-17(10-8-6-4-2)20-22-15-19(23-20)16-11-13-18(21)14-12-16/h11-15,17H,3-10H2,1-2H3,(H,22,23) | PDB
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| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour
Curated by ChEMBL
| Assay Description
Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain |
Bioorg Med Chem Lett 14: 3521-3 (2004)
BindingDB Entry DOI: 10.7270/Q2474D2N |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50223735
(CHEMBL119139)Show SMILES C(Cc1nc(c[nH]1)-c1ccc(cc1)-c1ccccc1)C1CCCCC1 Show InChI InChI=1S/C23H26N2/c1-3-7-18(8-4-1)11-16-23-24-17-22(25-23)21-14-12-20(13-15-21)19-9-5-2-6-10-19/h2,5-6,9-10,12-15,17-18H,1,3-4,7-8,11,16H2,(H,24,25) | PDB
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| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour
Curated by ChEMBL
| Assay Description
Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain |
Bioorg Med Chem Lett 14: 3521-3 (2004)
BindingDB Entry DOI: 10.7270/Q2474D2N |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50223734
(CHEMBL331942)Show InChI InChI=1S/C19H28N2/c1-4-5-6-7-8-19-20-14-18(21-19)17-11-9-16(10-12-17)13-15(2)3/h9-12,14-15H,4-8,13H2,1-3H3,(H,20,21) | PDB
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| CHEMBL
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PC sid
UniChem
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| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour
Curated by ChEMBL
| Assay Description
Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain |
Bioorg Med Chem Lett 14: 3521-3 (2004)
BindingDB Entry DOI: 10.7270/Q2474D2N |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50223733
(CHEMBL120306)Show InChI InChI=1S/C20H30N2/c1-6-8-16(9-7-2)19-21-14-18(22-19)15-10-12-17(13-11-15)20(3,4)5/h10-14,16H,6-9H2,1-5H3,(H,21,22) | PDB
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| CHEMBL
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| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour
Curated by ChEMBL
| Assay Description
Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain |
Bioorg Med Chem Lett 14: 3521-3 (2004)
BindingDB Entry DOI: 10.7270/Q2474D2N |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50539904
(CHEMBL4647764)Show SMILES CC(C)(C)c1cnc(CSc2cnc(N[C@@H]3CCCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)s2)o1 |r| Show InChI InChI=1S/C26H31N5O3S2/c1-5-21(32)29-18-10-8-17(9-11-18)24(33)31-12-6-7-19(15-31)30-25-28-14-23(36-25)35-16-22-27-13-20(34-22)26(2,3)4/h5,8-11,13-14,19H,1,6-7,12,15-16H2,2-4H3,(H,28,30)(H,29,32)/t19-/m1/s1 | PDB
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Harvard Medical School
Curated by ChEMBL
| Assay Description
Inhibition of human CDK13/cyclin K using Pol2-CTD as substrate by [gamma-33P]ATP-based radioisotope filter binding assay |
J Med Chem 63: 6708-6726 (2020)
Article DOI: 10.1021/acs.jmedchem.9b01929
BindingDB Entry DOI: 10.7270/Q25M698Z |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50573506
(CHEMBL4861833)Show SMILES CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12 |r| | PDB
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TBA
| Assay Description
Inhibition of human recombinant CDK13/CyclinK assessed as reduction in substrate phosphorylation using His-c-Myc as substrate preincubated with enzym... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113481
BindingDB Entry DOI: 10.7270/Q22B92TP |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM2579
((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1 | PDB
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Takeda Pharmaceutical Company Limited
Curated by ChEMBL
| Assay Description
Inhibition of N-terminal FLAG-tagged human full-length CDK13 (1 to 1512 residues)/N-terminal His-tagged CycK (1 to 580 residues) expressed in Sf9 cel... |
J Med Chem 61: 7710-7728 (2018)
Article DOI: 10.1021/acs.jmedchem.8b00683
BindingDB Entry DOI: 10.7270/Q2HX1G6F |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50597419
(CHEMBL5182767)Show SMILES CC(C)c1n[nH]c2c(NCc3ccc(cc3)-n3ccnc3)nc(SCCN)nc12 | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02184
BindingDB Entry DOI: 10.7270/Q26114CS |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50528813
(CHEMBL4163879)Show SMILES CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12 |r| Show InChI InChI=1S/C30H32ClN7O2/c1-37(2)15-6-10-27(39)34-21-13-11-20(12-14-21)29(40)38-16-5-7-22(19-38)35-30-33-18-25(31)28(36-30)24-17-32-26-9-4-3-8-23(24)26/h3-4,6,8-14,17-18,22,32H,5,7,15-16,19H2,1-2H3,(H,34,39)(H,33,35,36)/b10-6+/t22-/m1/s1 | PDB
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TBA
| Assay Description
Inhibition of CDK13/human cyclin K expressed in baculovirus-infected insect cells using pol2 CTD-peptide substrate and [gammaP]ATP by scintillation c... |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.0c00766
BindingDB Entry DOI: 10.7270/Q2GX4G9M |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50540080
(CHEMBL4648857)Show SMILES CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)N1CCC[C@@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12 |r| Show InChI InChI=1S/C30H32ClN7O2/c1-37(2)15-6-10-27(39)34-21-13-11-20(12-14-21)29(40)38-16-5-7-22(19-38)35-30-33-18-25(31)28(36-30)24-17-32-26-9-4-3-8-23(24)26/h3-4,6,8-14,17-18,22,32H,5,7,15-16,19H2,1-2H3,(H,34,39)(H,33,35,36)/b10-6+/t22-/m0/s1 | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c01719
BindingDB Entry DOI: 10.7270/Q2HQ43WX |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50528813
(CHEMBL4163879)Show SMILES CN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12 |r| Show InChI InChI=1S/C30H32ClN7O2/c1-37(2)15-6-10-27(39)34-21-13-11-20(12-14-21)29(40)38-16-5-7-22(19-38)35-30-33-18-25(31)28(36-30)24-17-32-26-9-4-3-8-23(24)26/h3-4,6,8-14,17-18,22,32H,5,7,15-16,19H2,1-2H3,(H,34,39)(H,33,35,36)/b10-6+/t22-/m1/s1 | PDB
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Eli Lilly and Company
Curated by ChEMBL
| Assay Description
Competitive irreversible inhibition of CDK13/cyclinK (unknown origin) in presence of Km ATP |
Bioorg Med Chem Lett 29: (2019)
Article DOI: 10.1016/j.bmcl.2019.126637
BindingDB Entry DOI: 10.7270/Q23F4T3T |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50223722
(CHEMBL334104)Show SMILES C(C1CCCCC1)c1nc(c[nH]1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C22H24N2/c1-3-7-17(8-4-1)15-22-23-16-21(24-22)20-13-11-19(12-14-20)18-9-5-2-6-10-18/h2,5-6,9-14,16-17H,1,3-4,7-8,15H2,(H,23,24) | PDB
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| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour
Curated by ChEMBL
| Assay Description
Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain |
Bioorg Med Chem Lett 14: 3521-3 (2004)
BindingDB Entry DOI: 10.7270/Q2474D2N |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50143966
(2-Chloro-N-[2-{4-[3-(4-fluoro-phenoxy)-2-hydroxy-p...)Show SMILES OC(COc1ccc(F)cc1)CN1CCN(CC1)C(CNS(=O)(=O)c1ccccc1Cl)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C28H30ClF4N3O4S/c29-25-3-1-2-4-27(25)41(38,39)34-17-26(20-5-7-21(8-6-20)28(31,32)33)36-15-13-35(14-16-36)18-23(37)19-40-24-11-9-22(30)10-12-24/h1-12,23,26,34,37H,13-19H2 | PDB
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| n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane |
Bioorg Med Chem Lett 14: 2025-30 (2004)
Article DOI: 10.1016/j.bmcl.2004.02.078
BindingDB Entry DOI: 10.7270/Q22J6B8R |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50223723
(CHEMBL119494)Show InChI InChI=1S/C20H30N2/c1-3-5-8-14-18(15-9-6-4-2)20-21-16-19(22-20)17-12-10-7-11-13-17/h7,10-13,16,18H,3-6,8-9,14-15H2,1-2H3,(H,21,22) | PDB
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| n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour
Curated by ChEMBL
| Assay Description
Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain |
Bioorg Med Chem Lett 14: 3521-3 (2004)
BindingDB Entry DOI: 10.7270/Q2474D2N |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50143963
(CHEMBL64869 | N-[2-{4-[3-(4-Bromo-phenoxy)-2-hydro...)Show SMILES Cc1cccc(c1)S(=O)(=O)NCC(N1CCN(CC(O)COc2ccc(Br)cc2)CC1)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C29H33BrF3N3O4S/c1-21-3-2-4-27(17-21)41(38,39)34-18-28(22-5-7-23(8-6-22)29(31,32)33)36-15-13-35(14-16-36)19-25(37)20-40-26-11-9-24(30)10-12-26/h2-12,17,25,28,34,37H,13-16,18-20H2,1H3 | PDB
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ArQule Inc
Curated by ChEMBL
| Assay Description
Inhibitory concentration against [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in vitro in rat cerebral cortex membrane at ... |
Bioorg Med Chem Lett 14: 2025-30 (2004)
Article DOI: 10.1016/j.bmcl.2004.02.078
BindingDB Entry DOI: 10.7270/Q22J6B8R |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50223725
(CHEMBL118682)Show InChI InChI=1S/C22H26N2/c1-3-8-20(9-4-2)22-23-16-21(24-22)19-14-12-18(13-15-19)17-10-6-5-7-11-17/h5-7,10-16,20H,3-4,8-9H2,1-2H3,(H,23,24) | PDB
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| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour
Curated by ChEMBL
| Assay Description
Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain |
Bioorg Med Chem Lett 14: 3521-3 (2004)
BindingDB Entry DOI: 10.7270/Q2474D2N |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50082319
((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)Show SMILES O[C@@H](COc1ccccc1)CN1CCC(CC1)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H29NO3/c28-23(20-29-24-7-3-1-4-8-24)19-27-17-15-22(16-18-27)21-11-13-26(14-12-21)30-25-9-5-2-6-10-25/h1-14,22-23,28H,15-20H2/t23-/m1/s1 | PDB
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| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research
Curated by ChEMBL
| Assay Description
Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G |
Bioorg Med Chem Lett 9: 2999-3002 (1999)
BindingDB Entry DOI: 10.7270/Q2D21Z3B |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50573513
(CHEMBL4866757)Show SMILES C\C=C\C(=O)Nc1ccc(nc1)N1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12 |r| | PDB
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| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant CDK13/CyclinK assessed as reduction in substrate phosphorylation using His-c-Myc as substrate preincubated with enzym... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113481
BindingDB Entry DOI: 10.7270/Q22B92TP |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50597407
(CHEMBL5191136)Show SMILES CC(O)CSc1nc(NCc2ccc(cc2)-n2cccn2)c2n[nH]c(C(C)C)c2n1 | PDB
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TBA
| |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c02184
BindingDB Entry DOI: 10.7270/Q26114CS |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50573511
(CHEMBL4864697)Show SMILES C\C=C\C(=O)Nc1ccc(cc1)N1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12 |r| | PDB
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| n/a | n/a | 123 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant CDK13/CyclinK assessed as reduction in substrate phosphorylation using His-c-Myc as substrate preincubated with enzym... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113481
BindingDB Entry DOI: 10.7270/Q22B92TP |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50573515
(CHEMBL4853887)Show SMILES C\C=C\C(=O)Nc1ccc(N2CCC[C@H](C2)Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)c(F)c1 |r| | PDB
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TBA
| Assay Description
Inhibition of human recombinant CDK13/CyclinK assessed as reduction in substrate phosphorylation using His-c-Myc as substrate preincubated with enzym... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113481
BindingDB Entry DOI: 10.7270/Q22B92TP |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50082324
((S)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)Show SMILES O[C@H](COc1ccccc1)CN1CCC(CC1)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H29NO3/c28-23(20-29-24-7-3-1-4-8-24)19-27-17-15-22(16-18-27)21-11-13-26(14-12-21)30-25-9-5-2-6-10-25/h1-14,22-23,28H,15-20H2/t23-/m0/s1 | PDB
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| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research
Curated by ChEMBL
| Assay Description
Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G |
Bioorg Med Chem Lett 9: 2999-3002 (1999)
BindingDB Entry DOI: 10.7270/Q2D21Z3B |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50473876
(CHEMBL2112614)Show SMILES [H][C@]12Cc3c(O)cccc3C(C)(CCN1C[C@H](C)OCc1ccccc1)C2C |THB:15:14:26:9.3.2,8:9:26:14.12.13| Show InChI InChI=1S/C24H31NO2/c1-17(27-16-19-8-5-4-6-9-19)15-25-13-12-24(3)18(2)22(25)14-20-21(24)10-7-11-23(20)26/h4-11,17-18,22,26H,12-16H2,1-3H3/t17-,18?,22+,24?/m0/s1 | PDB
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| n/a | n/a | 134 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG
Curated by ChEMBL
| Assay Description
Inhibitory effect against veratridine-induced glutamate release from rat brain slices |
J Med Chem 45: 3755-64 (2002)
Article DOI: 10.1021/jm020875j
BindingDB Entry DOI: 10.7270/Q2ZS308Z |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50223729
(CHEMBL418863)Show InChI InChI=1S/C16H19FN2/c17-14-8-6-13(7-9-14)15-11-18-16(19-15)10-12-4-2-1-3-5-12/h6-9,11-12H,1-5,10H2,(H,18,19) | PDB
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| n/a | n/a | 146 | n/a | n/a | n/a | n/a | n/a | n/a |
Institut Henri Beaufour
Curated by ChEMBL
| Assay Description
Concentration required to inhibit [3H]BTX binding to Sodium channel of rat brain |
Bioorg Med Chem Lett 14: 3521-3 (2004)
BindingDB Entry DOI: 10.7270/Q2474D2N |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50143950
(CHEMBL305591 | N-Benzyl-2-{4-[3-(2,6-dimethyl-phen...)Show SMILES Cc1cccc(C)c1OCC(O)CN1CCN(CC1)C(C(=O)NCc1ccccc1)c1ccc(F)cc1 Show InChI InChI=1S/C30H36FN3O3/c1-22-7-6-8-23(2)29(22)37-21-27(35)20-33-15-17-34(18-16-33)28(25-11-13-26(31)14-12-25)30(36)32-19-24-9-4-3-5-10-24/h3-14,27-28,35H,15-21H2,1-2H3,(H,32,36) | PDB
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| n/a | n/a | 149 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane |
Bioorg Med Chem Lett 14: 2025-30 (2004)
Article DOI: 10.1016/j.bmcl.2004.02.078
BindingDB Entry DOI: 10.7270/Q22J6B8R |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50573510
(CHEMBL4866812)Show SMILES CN(C)C\C=C\C(=O)Nc1ccc(cc1)N1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12 |r| | PDB
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| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 178 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant CDK13/CyclinK assessed as reduction in substrate phosphorylation using His-c-Myc as substrate preincubated with enzym... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113481
BindingDB Entry DOI: 10.7270/Q22B92TP |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50573520
(CHEMBL4862284)Show SMILES CN(C)C\C=C\C(=O)Nc1ccc(O[C@H]2CCC[C@H](C2)Nc2ncc(Cl)c(n2)-c2c[nH]c3ccccc23)cc1 |r| | PDB
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| n/a | n/a | 182 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant CDK13/CyclinK assessed as reduction in substrate phosphorylation using His-c-Myc as substrate preincubated with enzym... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113481
BindingDB Entry DOI: 10.7270/Q22B92TP |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50573930
(CHEMBL4856177)Show SMILES CC(C)c1n(C)nc2ccc(cc12)-c1ccnc(Nc2ccc3c(ccnc3c2)N2CCN(C)CC2)n1 | PDB
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| n/a | n/a | 182 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human CDK13/cyclin-K incubated for 2 hrs by [gamma-33P]-ATP assay |
Citation and Details
Article DOI: 10.1021/acs.jmedchem.1c00271
BindingDB Entry DOI: 10.7270/Q2ZG6X2G |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50143952
(CHEMBL59712 | N-{1-[2-Hydroxy-3-(4-methoxy-phenoxy...)Show SMILES COc1ccc(OCC(O)CN2CCC(CC2)N(C(=O)c2ccc(OC)cc2)c2ccccc2)cc1 Show InChI InChI=1S/C29H34N2O5/c1-34-26-10-8-22(9-11-26)29(33)31(23-6-4-3-5-7-23)24-16-18-30(19-17-24)20-25(32)21-36-28-14-12-27(35-2)13-15-28/h3-15,24-25,32H,16-21H2,1-2H3 | PDB
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| n/a | n/a | 183 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane |
Bioorg Med Chem Lett 14: 2025-30 (2004)
Article DOI: 10.1016/j.bmcl.2004.02.078
BindingDB Entry DOI: 10.7270/Q22J6B8R |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50573512
(CHEMBL4748005)Show SMILES CN(C)C\C=C\C(=O)Nc1ccc(nc1)N1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12 |r| | PDB
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| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 186 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant CDK13/CyclinK assessed as reduction in substrate phosphorylation using His-c-Myc as substrate preincubated with enzym... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113481
BindingDB Entry DOI: 10.7270/Q22B92TP |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50082323
(4-[4-(4-Fluoro-benzyl)-phenyl]-1-((E)-3-phenyl-all...)Show SMILES Fc1ccc(Cc2ccc(cc2)C2CCN(C\C=C\c3ccccc3)CC2)cc1 Show InChI InChI=1S/C27H28FN/c28-27-14-10-24(11-15-27)21-23-8-12-25(13-9-23)26-16-19-29(20-17-26)18-4-7-22-5-2-1-3-6-22/h1-15,26H,16-21H2/b7-4+ | PDB
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| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute for Biomedical Research
Curated by ChEMBL
| Assay Description
Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G |
Bioorg Med Chem Lett 9: 2999-3002 (1999)
BindingDB Entry DOI: 10.7270/Q2D21Z3B |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50143954
(CHEMBL433100 | N-(4-Fluoro-phenyl)-N-{1-[2-hydroxy...)Show SMILES COc1ccc(OCC(O)CN2CCC(CC2)N(C(=O)c2ccc(OC)cc2)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C29H33FN2O5/c1-35-26-9-3-21(4-10-26)29(34)32(23-7-5-22(30)6-8-23)24-15-17-31(18-16-24)19-25(33)20-37-28-13-11-27(36-2)12-14-28/h3-14,24-25,33H,15-20H2,1-2H3 | PDB
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PubMed
| n/a | n/a | 191 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane |
Bioorg Med Chem Lett 14: 2025-30 (2004)
Article DOI: 10.1016/j.bmcl.2004.02.078
BindingDB Entry DOI: 10.7270/Q22J6B8R |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50143958
(CHEMBL63060 | N-(4-Fluoro-phenyl)-N-{1-[2-hydroxy-...)Show SMILES COc1ccc(OCC(O)CN2CCC(CC2)N(C(=O)c2ccccc2)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C28H31FN2O4/c1-34-26-11-13-27(14-12-26)35-20-25(32)19-30-17-15-24(16-18-30)31(23-9-7-22(29)8-10-23)28(33)21-5-3-2-4-6-21/h2-14,24-25,32H,15-20H2,1H3 | PDB
UniProtKB/SwissProt
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| CHEMBL
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PC sid
UniChem
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PubMed
| n/a | n/a | 194 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane |
Bioorg Med Chem Lett 14: 2025-30 (2004)
Article DOI: 10.1016/j.bmcl.2004.02.078
BindingDB Entry DOI: 10.7270/Q22J6B8R |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50573516
(CHEMBL4853964)Show SMILES C\C=C\C(=O)Nc1cc(F)c(cc1C)N1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12 |r| | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
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AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 204 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant CDK13/CyclinK assessed as reduction in substrate phosphorylation using His-c-Myc as substrate preincubated with enzym... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113481
BindingDB Entry DOI: 10.7270/Q22B92TP |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50143962
(CHEMBL62878 | N-(2-{4-[3-(4-Chloro-phenoxy)-2-hydr...)Show SMILES OC(COc1ccc(Cl)cc1)CN1CCN(CC1)C(CNC(=O)c1ccc(cc1)C(F)(F)F)c1ccccc1 Show InChI InChI=1S/C29H31ClF3N3O3/c30-24-10-12-26(13-11-24)39-20-25(37)19-35-14-16-36(17-15-35)27(21-4-2-1-3-5-21)18-34-28(38)22-6-8-23(9-7-22)29(31,32)33/h1-13,25,27,37H,14-20H2,(H,34,38) | PDB
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| n/a | n/a | 208 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane |
Bioorg Med Chem Lett 14: 2025-30 (2004)
Article DOI: 10.1016/j.bmcl.2004.02.078
BindingDB Entry DOI: 10.7270/Q22J6B8R |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50143964
(4-Chloro-N-(4-fluoro-phenyl)-N-{1-[2-hydroxy-3-(4-...)Show SMILES COc1ccc(OCC(O)CN2CCC(CC2)N(C(=O)c2ccc(Cl)cc2)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C28H30ClFN2O4/c1-35-26-10-12-27(13-11-26)36-19-25(33)18-31-16-14-24(15-17-31)32(23-8-6-22(30)7-9-23)28(34)20-2-4-21(29)5-3-20/h2-13,24-25,33H,14-19H2,1H3 | PDB
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ArQule Inc
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane |
Bioorg Med Chem Lett 14: 2025-30 (2004)
Article DOI: 10.1016/j.bmcl.2004.02.078
BindingDB Entry DOI: 10.7270/Q22J6B8R |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50143975
(2-(4-Fluoro-phenyl)-2-{4-[2-hydroxy-3-(4-methoxy-p...)Show SMILES COc1ccc(CNC(=O)C(N2CCN(CC(O)COc3ccc(OC)cc3)CC2)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C30H36FN3O5/c1-37-26-9-3-22(4-10-26)19-32-30(36)29(23-5-7-24(31)8-6-23)34-17-15-33(16-18-34)20-25(35)21-39-28-13-11-27(38-2)12-14-28/h3-14,25,29,35H,15-21H2,1-2H3,(H,32,36) | PDB
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| n/a | n/a | 214 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane |
Bioorg Med Chem Lett 14: 2025-30 (2004)
Article DOI: 10.1016/j.bmcl.2004.02.078
BindingDB Entry DOI: 10.7270/Q22J6B8R |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50082319
((R)-1-Phenoxy-3-[4-(4-phenoxy-phenyl)-piperidin-1-...)Show SMILES O[C@@H](COc1ccccc1)CN1CCC(CC1)c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C26H29NO3/c28-23(20-29-24-7-3-1-4-8-24)19-27-17-15-22(16-18-27)21-11-13-26(14-12-21)30-25-9-5-2-6-10-25/h1-14,22-23,28H,15-20H2/t23-/m1/s1 | PDB
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Institute for Biomedical Research
Curated by ChEMBL
| Assay Description
Inhibition of veratridine-induced depolarization in rat cerebrocortical synaptosomes using the voltage sensitive fluorescent dye Rhodamine 6G |
Bioorg Med Chem Lett 9: 2999-3002 (1999)
BindingDB Entry DOI: 10.7270/Q2D21Z3B |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50143945
(4-Chloro-N-{1-[2-hydroxy-3-(4-methoxy-phenoxy)-pro...)Show SMILES COc1ccc(OCC(O)CN2CCC(CC2)N(C(=O)c2ccc(Cl)cc2)c2ccccc2)cc1 Show InChI InChI=1S/C28H31ClN2O4/c1-34-26-11-13-27(14-12-26)35-20-25(32)19-30-17-15-24(16-18-30)31(23-5-3-2-4-6-23)28(33)21-7-9-22(29)10-8-21/h2-14,24-25,32H,15-20H2,1H3 | PDB
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| n/a | n/a | 228 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane |
Bioorg Med Chem Lett 14: 2025-30 (2004)
Article DOI: 10.1016/j.bmcl.2004.02.078
BindingDB Entry DOI: 10.7270/Q22J6B8R |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 13/Cyclin-K
(Homo sapiens (Human)) | BDBM50573514
(CHEMBL4860981)Show SMILES C\C=C\C(=O)Nc1ccc(cc1C)N1CCC[C@H](C1)Nc1ncc(Cl)c(n1)-c1c[nH]c2ccccc12 |r| | PDB
KEGG
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antibodypedia
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| n/a | n/a | 239 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of human recombinant CDK13/CyclinK assessed as reduction in substrate phosphorylation using His-c-Myc as substrate preincubated with enzym... |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113481
BindingDB Entry DOI: 10.7270/Q22B92TP |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50143970
(CHEMBL61336 | N-(2-{4-[2-Hydroxy-3-(4-methoxy-phen...)Show SMILES COc1ccc(OCC(O)CN2CCN(CC2)C(CNC(=O)c2ccc(cc2)C(F)(F)F)c2ccccc2)cc1 Show InChI InChI=1S/C30H34F3N3O4/c1-39-26-11-13-27(14-12-26)40-21-25(37)20-35-15-17-36(18-16-35)28(22-5-3-2-4-6-22)19-34-29(38)23-7-9-24(10-8-23)30(31,32)33/h2-14,25,28,37H,15-21H2,1H3,(H,34,38) | PDB
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| n/a | n/a | 253 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc
Curated by ChEMBL
| Assay Description
Inhibitory concentration against [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in vitro in rat cerebral cortex membrane at ... |
Bioorg Med Chem Lett 14: 2025-30 (2004)
Article DOI: 10.1016/j.bmcl.2004.02.078
BindingDB Entry DOI: 10.7270/Q22J6B8R |
More data for this
Ligand-Target Pair | |
Sodium channel protein type 1/2/3 subunit alpha
(Rattus norvegicus) | BDBM50143957
(CHEMBL60847 | N-Benzyl-2-(4-fluoro-phenyl)-2-{4-[2...)Show SMILES COc1ccc(OCC(O)CN2CCN(CC2)C(C(=O)NCc2ccccc2)c2ccc(F)cc2)cc1 Show InChI InChI=1S/C29H34FN3O4/c1-36-26-11-13-27(14-12-26)37-21-25(34)20-32-15-17-33(18-16-32)28(23-7-9-24(30)10-8-23)29(35)31-19-22-5-3-2-4-6-22/h2-14,25,28,34H,15-21H2,1H3,(H,31,35) | PDB
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| n/a | n/a | 254 | n/a | n/a | n/a | n/a | n/a | n/a |
ArQule Inc
Curated by ChEMBL
| Assay Description
In vitro inhibition of [3H]-batrachotoxin binding to neurotoxin site 2 of sodium (Na+) channel in rat cerebral cortex membrane |
Bioorg Med Chem Lett 14: 2025-30 (2004)
Article DOI: 10.1016/j.bmcl.2004.02.078
BindingDB Entry DOI: 10.7270/Q22J6B8R |
More data for this
Ligand-Target Pair | |
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