Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50252103 ((2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-MET...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 3.84 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50031704 ((2S,4R)-2-Amino-4-methyl-pentanedioic acid | (2S,4...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 5.69 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50207593 ((S)-1-(2-AMINO-2-CARBOXYETHYL)-3(2-CARBOXYTHIOPHEN...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat GluK3 expressed in Sf9 cells | J Med Chem 54: 4793-805 (2011) Article DOI: 10.1021/jm2004078 BindingDB Entry DOI: 10.7270/Q2RR1ZM2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50002369 ((2S-(2alpha,3beta,4beta))-2-carboxy-4-(1-methyleth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 32.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426290 (CHEMBL2312682) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50252051 ((2S,4R)-2-amino-4-(3-(methylamino)-3-oxopropyl)pen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 57.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426285 (CHEMBL2312403) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 123 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426296 (CHEMBL2312396) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 185 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50126764 ((S)-2-amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL DrugBank MMDB PC cid PC sid UniChem Similars | Article PubMed | 199 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM from rat recombinant GluR7A expressed in baculovirus infected Sf9 cells | J Med Chem 52: 4911-22 (2009) Checked by Author Article DOI: 10.1021/jm900565c BindingDB Entry DOI: 10.7270/Q2R49RP9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426291 (CHEMBL2312681) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 217 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426289 (CHEMBL2312683) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 239 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426288 (CHEMBL2312684) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50240399 ((2R,3R,4S)-3-(carboxymethyl)-4-isopropylpyrrolidin...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 376 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat cloned iGluR7 | J Med Chem 51: 4085-92 (2008) Checked by Author Article DOI: 10.1021/jm800091e BindingDB Entry DOI: 10.7270/Q24M95FC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50240399 ((2R,3R,4S)-3-(carboxymethyl)-4-isopropylpyrrolidin...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 376 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Torino Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat iGluR7 receptor expressed in Sf9 cells baculovirus system after 1 to 2 hrs by liquid scintillation counting | J Med Chem 53: 4110-8 (2010) Article DOI: 10.1021/jm1001452 BindingDB Entry DOI: 10.7270/Q2RR206G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 494 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM17657 ((2S)-2-aminopentanedioic acid | (S)-Glu | D-Glutam...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 494 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50252048 ((2S,4R)-2-amino-4-(3-methoxy-3-oxopropyl)pentanedi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50349983 (CHEMBL1812596) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat GluK3 expressed in Sf9 cells | J Med Chem 54: 4793-805 (2011) Article DOI: 10.1021/jm2004078 BindingDB Entry DOI: 10.7270/Q2RR1ZM2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50295042 ((S)-2-Amino-3-((RS)-3-hydroxy-8-methyl-7,8-dihydro...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM from rat recombinant GluR7A expressed in baculovirus infected Sf9 cells | J Med Chem 52: 4911-22 (2009) Checked by Author Article DOI: 10.1021/jm900565c BindingDB Entry DOI: 10.7270/Q2R49RP9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM17660 ((2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.67E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50034501 ((S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid | ...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | 1.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H[SYM2081 from rat recombinant GluK3a expressed in sS9 cells | J Med Chem 53: 8354-8361 (2010) Article DOI: 10.1021/jm101218a BindingDB Entry DOI: 10.7270/Q20Z73HW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50263220 (CHEMBL4075364) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 2.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Biotechnology, Chemistry and Pharmacy, (DoE 2018-2022) NatSynDrugs , University of Siena , Via A. Moro 2 , 53100 Siena , Italy. Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from recombinant homomeric rat GluK3 receptor expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 61: 2124-2130 (2018) Article DOI: 10.1021/acs.jmedchem.8b00099 BindingDB Entry DOI: 10.7270/Q2WS8WQT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426286 (CHEMBL2312686) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50126763 ((S)-2-amino-3-(3-hydroxy-5-tert-butyl-4-isoxazolyl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars | Article PubMed | 2.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM from rat recombinant GluR7A expressed in baculovirus infected Sf9 cells | J Med Chem 52: 4911-22 (2009) Checked by Author Article DOI: 10.1021/jm900565c BindingDB Entry DOI: 10.7270/Q2R49RP9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426292 (CHEMBL2312402) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 2.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50252050 ((2S,4R)-2-amino-4-(3-amino-3-oxopropyl)pentanedioi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50252052 ((2S,4R)-2-amino-4-(3-(ethylamino)-3-oxopropyl)pent...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50252920 ((S)-1-[2'-Amino-2'-carboxyethyl]-5,7-dihydrothieno...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem | PDB Article PubMed | 3.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat GluK3 expressed in Sf9 cells | J Med Chem 54: 4793-805 (2011) Article DOI: 10.1021/jm2004078 BindingDB Entry DOI: 10.7270/Q2RR1ZM2 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426294 (CHEMBL2312399) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50252922 ((S)-1-(2'-Amino-2'-carboxyethyl)thieno[3,2-d]pyrim...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat GluK3 expressed in Sf9 cells | J Med Chem 54: 4793-805 (2011) Article DOI: 10.1021/jm2004078 BindingDB Entry DOI: 10.7270/Q2RR1ZM2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426295 (CHEMBL2312397) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 4.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50102172 (CHEMBL1835332) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | Bioorg Med Chem 22: 5368-77 (2014) Article DOI: 10.1016/j.bmc.2014.07.045 BindingDB Entry DOI: 10.7270/Q2TM7CXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50349981 (CHEMBL1812598) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 4.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat GluK3 expressed in Sf9 cells | J Med Chem 54: 4793-805 (2011) Article DOI: 10.1021/jm2004078 BindingDB Entry DOI: 10.7270/Q2RR1ZM2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50107595 ((S)-1-(2-Amino-2-carboxyethyl)-6,7-dihydro-1H-cycl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 5.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Biotechnology, Chemistry and Pharmacy, (DoE 2018-2022) NatSynDrugs , University of Siena , Via A. Moro 2 , 53100 Siena , Italy. Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from recombinant homomeric rat GluK3 receptor expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 61: 2124-2130 (2018) Article DOI: 10.1021/acs.jmedchem.8b00099 BindingDB Entry DOI: 10.7270/Q2WS8WQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50107595 ((S)-1-(2-Amino-2-carboxyethyl)-6,7-dihydro-1H-cycl...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 5.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat GluK3 expressed in Sf9 cells | J Med Chem 54: 4793-805 (2011) Article DOI: 10.1021/jm2004078 BindingDB Entry DOI: 10.7270/Q2RR1ZM2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426299 (CHEMBL2312398) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426297 (CHEMBL2312680) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 5.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426293 (CHEMBL2312400) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50349980 (CHEMBL1738726) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 7.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat GluK3 expressed in Sf9 cells | J Med Chem 54: 4793-805 (2011) Article DOI: 10.1021/jm2004078 BindingDB Entry DOI: 10.7270/Q2RR1ZM2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50426287 (CHEMBL2312685) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | J Med Chem 56: 1614-28 (2013) Article DOI: 10.1021/jm301433m BindingDB Entry DOI: 10.7270/Q23F4R0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50246919 (CHEMBL4099104) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Eastern Finland Curated by ChEMBL | Assay Description Displacement of [3H]-KA from recombinant homomeric rat GluK3a receptor expressed in baculovirus infected Sf9 insect cell membranes by scintillation c... | J Med Chem 60: 9885-9904 (2017) Article DOI: 10.1021/acs.jmedchem.7b01624 BindingDB Entry DOI: 10.7270/Q21R6SXD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50200522 (CHEMBL3983064) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Medical College Curated by ChEMBL | Assay Description Displacement of [3H]-kainate from rat recombinant GluK3 receptor expressed in baculovirus infected insect Sf9 cell membranes after 60 mins | Bioorg Med Chem Lett 26: 5568-5572 (2016) Article DOI: 10.1016/j.bmcl.2016.09.075 BindingDB Entry DOI: 10.7270/Q29S1T0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50200522 (CHEMBL3983064) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.12E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Jagiellonian University Medical College Curated by ChEMBL | Assay Description Displacement of [3H]-kainate from rat recombinant GluK3 receptor expressed in baculovirus infected insect Sf9 cell membranes after 60 mins | Bioorg Med Chem Lett 26: 5568-5572 (2016) Article DOI: 10.1016/j.bmcl.2016.09.075 BindingDB Entry DOI: 10.7270/Q29S1T0N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50355329 (CHEMBL1835336) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem | Article PubMed | 1.44E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | Bioorg Med Chem 22: 5368-77 (2014) Article DOI: 10.1016/j.bmc.2014.07.045 BindingDB Entry DOI: 10.7270/Q2TM7CXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50102171 (CHEMBL1835339) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou... | Bioorg Med Chem 22: 5368-77 (2014) Article DOI: 10.1016/j.bmc.2014.07.045 BindingDB Entry DOI: 10.7270/Q2TM7CXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50263224 (CHEMBL4066795) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | 1.81E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Biotechnology, Chemistry and Pharmacy, (DoE 2018-2022) NatSynDrugs , University of Siena , Via A. Moro 2 , 53100 Siena , Italy. Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from recombinant homomeric rat GluK3 receptor expressed in baculovirus infected Sf9 insect cell membranes | J Med Chem 61: 2124-2130 (2018) Article DOI: 10.1021/acs.jmedchem.8b00099 BindingDB Entry DOI: 10.7270/Q2WS8WQT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50102107 (CHEMBL3337656) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [3H]KA from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation counting | Bioorg Med Chem 22: 5368-77 (2014) Article DOI: 10.1016/j.bmc.2014.07.045 BindingDB Entry DOI: 10.7270/Q2TM7CXK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50251893 ((2S,4R)-2-amino-4-(3-(benzylamino)-3-oxopropyl)pen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 2.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universite Blaise Pascal Curated by ChEMBL | Assay Description Displacement of [3H]SYM2081 from rat recombinant iGluR7 | J Med Chem 51: 4093-103 (2008) Article DOI: 10.1021/jm800092x BindingDB Entry DOI: 10.7270/Q20V8DP6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate receptor ionotropic, kainate 3 (Rattus norvegicus) | BDBM50234096 (CHEMBL4084004) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
McGill University Curated by ChEMBL | Assay Description Displacement of [3H]kainic acid from eGFP-fused recombinant rat full length GluK3 receptor expressed in HEK293T/17 cells by liquid scintillation coun... | J Med Chem 60: 441-457 (2017) Article DOI: 10.1021/acs.jmedchem.6b01516 BindingDB Entry DOI: 10.7270/Q2G44SJJ | |||||||||||
More data for this Ligand-Target Pair |
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