Found 20 hits of ic50 for UniProtKB: P44514 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Succinyl-diaminopimelate desuccinylase
(Haemophilus influenzae) | BDBM21642
((2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolid...)Show InChI InChI=1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Loyola University
Curated by ChEMBL
| Assay Description Inhibition of Haemophilus influenzae recombinant DapE |
Bioorg Med Chem Lett 19: 6350-2 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.077 BindingDB Entry DOI: 10.7270/Q2833T06 |
More data for this Ligand-Target Pair | |
Succinyl-diaminopimelate desuccinylase
(Haemophilus influenzae) | BDBM50311534
(3-sulfanyl-L-valine | CHEMBL207222 | L-Penicillami...)Show InChI InChI=1S/C5H11NO2S/c1-5(2,9)3(6)4(7)8/h3,9H,6H2,1-2H3,(H,7,8)/t3-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Loyola University
Curated by ChEMBL
| Assay Description Inhibition of Haemophilus influenzae recombinant DapE |
Bioorg Med Chem Lett 19: 6350-2 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.077 BindingDB Entry DOI: 10.7270/Q2833T06 |
More data for this Ligand-Target Pair | |
Succinyl-diaminopimelate desuccinylase
(Haemophilus influenzae) | BDBM50311533
(3-Mercapto-benzoic acid | 3-Mercaptobenzoicacid | ...)Show InChI InChI=1S/C7H6O2S/c8-7(9)5-2-1-3-6(10)4-5/h1-4,10H,(H,8,9) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 3.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Loyola University
Curated by ChEMBL
| Assay Description Inhibition of Haemophilus influenzae recombinant DapE |
Bioorg Med Chem Lett 19: 6350-2 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.077 BindingDB Entry DOI: 10.7270/Q2833T06 |
More data for this Ligand-Target Pair | |
Succinyl-diaminopimelate desuccinylase
(Haemophilus influenzae) | BDBM50140754
((R)-1-((S)-3-Mercapto-2-methyl-propionyl)-pyrrolid...)Show InChI InChI=1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Loyola University
Curated by ChEMBL
| Assay Description Inhibition of Haemophilus influenzae recombinant DapE |
Bioorg Med Chem Lett 19: 6350-2 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.077 BindingDB Entry DOI: 10.7270/Q2833T06 |
More data for this Ligand-Target Pair | |
Succinyl-diaminopimelate desuccinylase
(Haemophilus influenzae) | BDBM50311532
(CHEMBL1076479 | delta-Mercaptobutyricacid)Show InChI InChI=1S/C4H8O2S/c5-4(6)2-1-3-7/h7H,1-3H2,(H,5,6) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | 4.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Loyola University
Curated by ChEMBL
| Assay Description Inhibition of Haemophilus influenzae recombinant DapE |
Bioorg Med Chem Lett 19: 6350-2 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.077 BindingDB Entry DOI: 10.7270/Q2833T06 |
More data for this Ligand-Target Pair | |
Succinyl-diaminopimelate desuccinylase
(Haemophilus influenzae) | BDBM50217941
((-)-penicillamine | (2S)-2-amino-3-methyl-3-sulfan...)Show InChI InChI=1S/C5H11NO2S/c1-5(2,9)3(6)4(7)8/h3,9H,6H2,1-2H3,(H,7,8)/t3-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Loyola University
Curated by ChEMBL
| Assay Description Inhibition of Haemophilus influenzae recombinant DapE |
Bioorg Med Chem Lett 19: 6350-2 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.077 BindingDB Entry DOI: 10.7270/Q2833T06 |
More data for this Ligand-Target Pair | |
Succinyl-diaminopimelate desuccinylase
(Haemophilus influenzae) | BDBM50613815
(CHEMBL5290013) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| UniChem
| | n/a | n/a | 5.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Succinyl-diaminopimelate desuccinylase
(Haemophilus influenzae) | BDBM50613818
(CHEMBL1427222) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| UniChem
| | n/a | n/a | 5.43E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Succinyl-diaminopimelate desuccinylase
(Haemophilus influenzae) | BDBM56042
(MLS000057408 | N-(5-chloranylpyridin-2-yl)-2-[(1-p...)Show InChI InChI=1S/C15H13ClN6OS/c1-10(14(23)18-13-8-7-11(16)9-17-13)24-15-19-20-21-22(15)12-5-3-2-4-6-12/h2-10H,1H3,(H,17,18,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| | n/a | n/a | 5.73E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Succinyl-diaminopimelate desuccinylase
(Haemophilus influenzae) | BDBM50067899
(2-Thiopheneboronicacid | CHEMBL141272 | Thiophene-...)Show InChI InChI=1S/C4H5BO2S/c6-5(7)4-2-1-3-8-4/h1-3,6-7H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 9.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Loyola University
Curated by ChEMBL
| Assay Description Inhibition of Haemophilus influenzae recombinant DapE |
Bioorg Med Chem Lett 19: 6350-2 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.077 BindingDB Entry DOI: 10.7270/Q2833T06 |
More data for this Ligand-Target Pair | |
Succinyl-diaminopimelate desuccinylase
(Haemophilus influenzae) | BDBM50240041
(1-phenyl-2-thiourea | 1-phenylthiourea | CHEMBL263...)Show InChI InChI=1S/C7H8N2S/c8-7(10)9-6-4-2-1-3-5-6/h1-5H,(H3,8,9,10) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Loyola University
Curated by ChEMBL
| Assay Description Inhibition of Haemophilus influenzae recombinant DapE |
Bioorg Med Chem Lett 19: 6350-2 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.077 BindingDB Entry DOI: 10.7270/Q2833T06 |
More data for this Ligand-Target Pair | |
Succinyl-diaminopimelate desuccinylase
(Haemophilus influenzae) | BDBM50613816
(CHEMBL5284526) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| UniChem
| | n/a | n/a | 1.03E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Succinyl-diaminopimelate desuccinylase
(Haemophilus influenzae) | BDBM26996
(CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phe...)Show InChI InChI=1S/C6H7BO2/c8-7(9)6-4-2-1-3-5-6/h1-5,8-9H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.07E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Loyola University
Curated by ChEMBL
| Assay Description Inhibition of Haemophilus influenzae recombinant DapE |
Bioorg Med Chem Lett 19: 6350-2 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.077 BindingDB Entry DOI: 10.7270/Q2833T06 |
More data for this Ligand-Target Pair | |
Succinyl-diaminopimelate desuccinylase
(Haemophilus influenzae) | BDBM50613817
(CHEMBL5282444) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| UniChem
| | n/a | n/a | 1.34E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this Ligand-Target Pair | |
Succinyl-diaminopimelate desuccinylase
(Haemophilus influenzae) | BDBM50017129
((S)-1-((S)-2-((R)-1-ethoxy-1-oxo-4-phenylbutan-2-y...)Show SMILES CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O |r| Show InChI InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Loyola University
Curated by ChEMBL
| Assay Description Inhibition of Haemophilus influenzae recombinant DapE |
Bioorg Med Chem Lett 19: 6350-2 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.077 BindingDB Entry DOI: 10.7270/Q2833T06 |
More data for this Ligand-Target Pair | |
Succinyl-diaminopimelate desuccinylase
(Haemophilus influenzae) | BDBM50099857
(ACETOHYDROXAMIC ACID (AHA) | AHA | Acethydroxamsae...)Show InChI InChI=1S/C2H5NO2/c1-2(4)3-5/h5H,1H3,(H,3,4) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Loyola University
Curated by ChEMBL
| Assay Description Inhibition of Haemophilus influenzae recombinant DapE |
Bioorg Med Chem Lett 19: 6350-2 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.077 BindingDB Entry DOI: 10.7270/Q2833T06 |
More data for this Ligand-Target Pair | |
Succinyl-diaminopimelate desuccinylase
(Haemophilus influenzae) | BDBM50311535
(CHEMBL1086896 | N-(Benzyloxycarbonyl)hydroxylamine)Show InChI InChI=1S/C8H9NO3/c10-8(9-11)12-6-7-4-2-1-3-5-7/h1-5,11H,6H2,(H,9,10) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Loyola University
Curated by ChEMBL
| Assay Description Inhibition of Haemophilus influenzae recombinant DapE |
Bioorg Med Chem Lett 19: 6350-2 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.077 BindingDB Entry DOI: 10.7270/Q2833T06 |
More data for this Ligand-Target Pair | |
Succinyl-diaminopimelate desuccinylase
(Haemophilus influenzae) | BDBM50311531
((2-Carboxyethyl)-phosphonic acid | 3-PHOSPHONOPROP...)Show InChI InChI=1S/C3H7O5P/c4-3(5)1-2-9(6,7)8/h1-2H2,(H,4,5)(H2,6,7,8) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | 1.62E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
Loyola University
Curated by ChEMBL
| Assay Description Inhibition of Haemophilus influenzae recombinant DapE |
Bioorg Med Chem Lett 19: 6350-2 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.077 BindingDB Entry DOI: 10.7270/Q2833T06 |
More data for this Ligand-Target Pair | |
Succinyl-diaminopimelate desuccinylase
(Haemophilus influenzae) | BDBM50067893
(3-Carboxyphenylboronicacid | 3-boronobenzoic acid ...)Show InChI InChI=1S/C7H7BO4/c9-7(10)5-2-1-3-6(4-5)8(11)12/h1-4,11-12H,(H,9,10) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | >1.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Loyola University
Curated by ChEMBL
| Assay Description Inhibition of Haemophilus influenzae recombinant DapE |
Bioorg Med Chem Lett 19: 6350-2 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.077 BindingDB Entry DOI: 10.7270/Q2833T06 |
More data for this Ligand-Target Pair | |
Succinyl-diaminopimelate desuccinylase
(Haemophilus influenzae) | BDBM50067885
(4-CARBOXYPHENYLBORONIC ACID | 4-Carboxyphenylboron...)Show InChI InChI=1S/C7H7BO4/c9-7(10)5-1-3-6(4-2-5)8(11)12/h1-4,11-12H,(H,9,10) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
Loyola University
Curated by ChEMBL
| Assay Description Inhibition of Haemophilus influenzae recombinant DapE |
Bioorg Med Chem Lett 19: 6350-2 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.077 BindingDB Entry DOI: 10.7270/Q2833T06 |
More data for this Ligand-Target Pair | |