Found 12 hits of ic50 data for polymerid = 50004814 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Autoinducer 1 sensor kinase/phosphatase LuxN
(Vibrio harveyi) | BDBM50351500
(CHEMBL1823949)Show InChI InChI=1S/C22H27NO2/c1-22(2,17-8-4-3-5-9-17)18-12-14-20(15-13-18)25-16-21(24)23-19-10-6-7-11-19/h3-5,8-9,12-15,19H,6-7,10-11,16H2,1-2H3,(H,23,24) | UniProtKB/SwissProt
GoogleScholar
AffyNet 
| Purchase
CHEMBL
PC cid
PC sid
UniChem
| | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Autoinducer 1 sensor kinase/phosphatase LuxN
(Vibrio harveyi) | BDBM50351500
(CHEMBL1823949)Show InChI InChI=1S/C22H27NO2/c1-22(2,17-8-4-3-5-9-17)18-12-14-20(15-13-18)25-16-21(24)23-19-10-6-7-11-19/h3-5,8-9,12-15,19H,6-7,10-11,16H2,1-2H3,(H,23,24) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of LuxN-dependent bioluminescence in Vibrio harveyi |
J Med Chem 53: 7467-89 (2010)
Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT |
More data for this
Ligand-Target Pair | |
Autoinducer 1 sensor kinase/phosphatase LuxN
(Vibrio harveyi) | BDBM50351501
(CHEMBL1823948)Show SMILES Clc1ccc(cc1)C(=O)c1ccc(cc1)S(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H12Cl2O3S/c20-15-5-1-13(2-6-15)19(22)14-3-9-17(10-4-14)25(23,24)18-11-7-16(21)8-12-18/h1-12H | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of LuxN-dependent bioluminescence in Vibrio harveyi |
J Med Chem 53: 7467-89 (2010)
Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT |
More data for this
Ligand-Target Pair | |
Autoinducer 1 sensor kinase/phosphatase LuxN
(Vibrio harveyi) | BDBM50615759
(CHEMBL5271255) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Autoinducer 1 sensor kinase/phosphatase LuxN
(Vibrio harveyi) | BDBM50351503
(CHEMBL1823946)Show SMILES CC(C)CC(NS(=O)(=O)c1ccc2CCN(C(C)=O)c2c1)C(=O)NCc1ccc(Cl)cc1 Show InChI InChI=1S/C23H28ClN3O4S/c1-15(2)12-21(23(29)25-14-17-4-7-19(24)8-5-17)26-32(30,31)20-9-6-18-10-11-27(16(3)28)22(18)13-20/h4-9,13,15,21,26H,10-12,14H2,1-3H3,(H,25,29) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of LuxN-dependent bioluminescence in Vibrio harveyi |
J Med Chem 53: 7467-89 (2010)
Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT |
More data for this
Ligand-Target Pair | |
Autoinducer 1 sensor kinase/phosphatase LuxN
(Vibrio harveyi) | BDBM50615758
(CHEMBL5265893) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Autoinducer 1 sensor kinase/phosphatase LuxN
(Vibrio harveyi) | BDBM50615764
(CHEMBL5279572) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| UniChem
| | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Autoinducer 1 sensor kinase/phosphatase LuxN
(Vibrio harveyi) | BDBM50351502
(CHEMBL1823947)Show SMILES COc1ccc(CNC(=O)C(NS(=O)(=O)c2ccc3nc(C)sc3c2)C(C)C)cc1 Show InChI InChI=1S/C21H25N3O4S2/c1-13(2)20(21(25)22-12-15-5-7-16(28-4)8-6-15)24-30(26,27)17-9-10-18-19(11-17)29-14(3)23-18/h5-11,13,20,24H,12H2,1-4H3,(H,22,25) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of LuxN-dependent bioluminescence in Vibrio harveyi |
J Med Chem 53: 7467-89 (2010)
Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT |
More data for this
Ligand-Target Pair | |
Autoinducer 1 sensor kinase/phosphatase LuxN
(Vibrio harveyi) | BDBM50351502
(CHEMBL1823947)Show SMILES COc1ccc(CNC(=O)C(NS(=O)(=O)c2ccc3nc(C)sc3c2)C(C)C)cc1 Show InChI InChI=1S/C21H25N3O4S2/c1-13(2)20(21(25)22-12-15-5-7-16(28-4)8-6-15)24-30(26,27)17-9-10-18-19(11-17)29-14(3)23-18/h5-11,13,20,24H,12H2,1-4H3,(H,22,25) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Autoinducer 1 sensor kinase/phosphatase LuxN
(Vibrio harveyi) | BDBM50106538
(3'-amino-3'-deoxyadenosine | 4-Amino-2-(6-amino-pu...)Show SMILES N[C@@H]1[C@@H](CO)O[C@H]([C@@H]1O)n1cnc2c(N)ncnc12 Show InChI InChI=1S/C10H14N6O3/c11-5-4(1-17)19-10(7(5)18)16-3-15-6-8(12)13-2-14-9(6)16/h2-5,7,10,17-18H,1,11H2,(H2,12,13,14)/t4-,5-,7-,10-/m1/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Autoinducer 1 sensor kinase/phosphatase LuxN
(Vibrio harveyi) | BDBM50351499
(CHEMBL1823950)Show InChI InChI=1S/C12H14N2O2S/c1-8(2)16-11(15)7-17-12-13-9-5-3-4-6-10(9)14-12/h3-6,8H,7H2,1-2H3,(H,13,14) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of LuxN-dependent bioluminescence in Vibrio harveyi |
J Med Chem 53: 7467-89 (2010)
Article DOI: 10.1021/jm901742e
BindingDB Entry DOI: 10.7270/Q2S75GPT |
More data for this
Ligand-Target Pair | |
Autoinducer 1 sensor kinase/phosphatase LuxN
(Vibrio harveyi) | BDBM50351499
(CHEMBL1823950)Show InChI InChI=1S/C12H14N2O2S/c1-8(2)16-11(15)7-17-12-13-9-5-3-4-6-10(9)14-12/h3-6,8H,7H2,1-2H3,(H,13,14) | UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| | n/a | n/a | 6.25E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
|
More data for this
Ligand-Target Pair | |
Search and Browse
