Compile Data Set for Download or QSAR

Found 6 hits of ic50 data for polymerid = 50006318   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dynamin-2 (Rattus norvegicus)	BDBM50423883 (CHEMBL2312430) Show SMILES CCCCCCCCCCNCc1cn(CCCN(C)C)c2ccccc12 Show InChI InChI=1S/C24H41N3/c1-4-5-6-7-8-9-10-13-17-25-20-22-21-27(19-14-18-26(2)3)24-16-12-11-15-23(22)24/h11-12,15-16,21,25H,4-10,13-14,17-20H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of rat full length His6-tagged dyn2 using phosphotidylserine as substrate after 90 mins by malachite green GTPase assay in presence of GTP				J Med Chem 56: 46-59 (2013) Article DOI: 10.1021/jm300844m BindingDB Entry DOI: 10.7270/Q2DJ5GZ3
					More data for this Ligand-Target Pair
Dynamin-2 (Rattus norvegicus)	BDBM50055861 (CHEMBL3329968) Show SMILES OC(=O)c1ccc(NC2=CC(=O)C(Nc3ccc(cc3)C(O)=O)=CC2=O)cc1 |c:23,t:8| Show InChI InChI=1S/C20H14N2O6/c23-17-10-16(22-14-7-3-12(4-8-14)20(27)28)18(24)9-15(17)21-13-5-1-11(2-6-13)19(25)26/h1-10,21-22H,(H,25,26)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of phosphatidylserine-stimulated GTPase activity of recombinant rat Dynamin 2 expressed in Sf21 cells assessed as inhibition of orthophosp...				Eur J Med Chem 85: 191-206 (2014) Article DOI: 10.1016/j.ejmech.2014.06.070 BindingDB Entry DOI: 10.7270/Q28G8NCR
					More data for this Ligand-Target Pair
Dynamin-2 (Rattus norvegicus)	BDBM50055860 (CHEMBL3329967) Show SMILES OC(=O)c1cccc(NC2=CC(=O)C(Nc3cccc(c3)C(O)=O)=CC2=O)c1 |c:24,t:9| Show InChI InChI=1S/C20H14N2O6/c23-17-10-16(22-14-6-2-4-12(8-14)20(27)28)18(24)9-15(17)21-13-5-1-3-11(7-13)19(25)26/h1-10,21-22H,(H,25,26)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of phosphatidylserine-stimulated GTPase activity of recombinant rat Dynamin 2 expressed in Sf21 cells assessed as inhibition of orthophosp...				Eur J Med Chem 85: 191-206 (2014) Article DOI: 10.1016/j.ejmech.2014.06.070 BindingDB Entry DOI: 10.7270/Q28G8NCR
					More data for this Ligand-Target Pair
Dynamin-2 (Rattus norvegicus)	BDBM50268295 (2-Cyano-N-octyl-3-(1-(3-dimethylaminopropyl)-1H-in...) Show SMILES CCCCCCCCNC(=O)C(=C\c1cn(CCCN(C)C)c2ccccc12)\C#N Show InChI InChI=1S/C25H36N4O/c1-4-5-6-7-8-11-15-27-25(30)21(19-26)18-22-20-29(17-12-16-28(2)3)24-14-10-9-13-23(22)24/h9-10,13-14,18,20H,4-8,11-12,15-17H2,1-3H3,(H,27,30)/b21-18+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of rat full length His6-tagged dyn2 using phosphotidylserine as substrate after 90 mins by malachite green GTPase assay in presence of GTP				J Med Chem 56: 46-59 (2013) Article DOI: 10.1021/jm300844m BindingDB Entry DOI: 10.7270/Q2DJ5GZ3
					More data for this Ligand-Target Pair
Dynamin-2 (Rattus norvegicus)	BDBM50055859 (CHEMBL3329966) Show SMILES Oc1ccc(NC2=CC(=O)C(Nc3ccc(O)cc3)=CC2=O)cc1 |c:19,t:6| Show InChI InChI=1S/C18H14N2O4/c21-13-5-1-11(2-6-13)19-15-9-18(24)16(10-17(15)23)20-12-3-7-14(22)8-4-12/h1-10,19-22H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.36E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of phosphatidylserine-stimulated GTPase activity of recombinant rat Dynamin 2 expressed in Sf21 cells assessed as inhibition of orthophosp...				Eur J Med Chem 85: 191-206 (2014) Article DOI: 10.1016/j.ejmech.2014.06.070 BindingDB Entry DOI: 10.7270/Q28G8NCR
					More data for this Ligand-Target Pair
Dynamin-2 (Rattus norvegicus)	BDBM50055862 (CHEMBL3329969) Show SMILES Oc1cccc(NC2=CC(=O)C(Nc3cccc(O)c3)=CC2=O)c1 |c:20,t:7| Show InChI InChI=1S/C18H14N2O4/c21-13-5-1-3-11(7-13)19-15-9-18(24)16(10-17(15)23)20-12-4-2-6-14(22)8-12/h1-10,19-22H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Newcastle Curated by ChEMBL					Assay Description Inhibition of phosphatidylserine-stimulated GTPase activity of recombinant rat Dynamin 2 expressed in Sf21 cells assessed as inhibition of orthophosp...				Eur J Med Chem 85: 191-206 (2014) Article DOI: 10.1016/j.ejmech.2014.06.070 BindingDB Entry DOI: 10.7270/Q28G8NCR
					More data for this Ligand-Target Pair