Compile Data Set for Download or QSAR

Found 226 hits of ic50 for UniProtKB: P21675   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346431 (US10202378, Example 44 | ethyl 2,6-dimethyl-7-oxo-...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(O)(c1cccc(c1)-c1cc[nH]n1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346545 (2-methylbutyl 4-(3-hydroxy-3-methyl-but-1-ynyl)-2,...) Show SMILES CCC(C)COC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(C)O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19.4	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346540 ((1-acetyl-4-piperidyl)methyl4-(3-hydroxy-3-methyl-...) Show SMILES CC(=O)N1CCC(COC(=O)c2c(C)[nH]c3c2c(cn(C)c3=O)C#CC(C)(C)O)CC1 Show InChI InChI=1S/C23H29N3O5/c1-14-18(22(29)31-13-16-7-10-26(11-8-16)15(2)27)19-17(6-9-23(3,4)30)12-25(5)21(28)20(19)24-14/h12,16,24,30H,7-8,10-11,13H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.1	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346476 (US10202378, Example 89 | US10202378, Example 93a |...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(O)(C(F)F)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21.4	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346517 (US10202378, Example 121 | o-tolylmethyl 4-(3-hydro...) Show SMILES Cc1[nH]c2c(c1C(=O)OCc1ccccc1C)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C23H24N2O4/c1-14-8-6-7-9-17(14)13-29-22(27)18-15(2)24-20-19(18)16(10-11-23(3,4)28)12-25(5)21(20)26/h6-9,12,24,28H,13H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21.5	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346428 (US10202378, Example 41 | ethyl 2,6-dimethyl-7-oxo-...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(O)(c1cccc(c1)-c1cn[nH]c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21.5	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346561 ((3-amino-1,1-dimethyl-propyl) 4-(3-hydroxy-3-methy...) Show SMILES Cc1[nH]c2c(c1C(=O)OC(C)(C)CCN)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C20H27N3O4/c1-12-14(18(25)27-20(4,5)9-10-21)15-13(7-8-19(2,3)26)11-23(6)17(24)16(15)22-12/h11,22,26H,9-10,21H2,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21.7	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346405 (US10202378, Example 20 | ethyl 4-[2-(1-hydroxycycl...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC1(O)CCCC1 Show InChI InChI=1S/C19H22N2O4/c1-4-25-18(23)14-12(2)20-16-15(14)13(11-21(3)17(16)22)7-10-19(24)8-5-6-9-19/h11,20,24H,4-6,8-9H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21.9	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346467 (US10202378, Example 80 | ethyl 4-(3-hydroxy-3-phen...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22.6	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346549 (US10202378, Example 153 | cyclohexylmethyl 4-(3-hy...) Show SMILES Cc1[nH]c2c(c1C(=O)OCC1CCCCC1)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C22H28N2O4/c1-14-17(21(26)28-13-15-8-6-5-7-9-15)18-16(10-11-22(2,3)27)12-24(4)20(25)19(18)23-14/h12,15,23,27H,5-9,13H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22.6	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346544 (US10202378, Example 148 | cyclopentylmethyl 4-(3-h...) Show SMILES Cc1[nH]c2c(c1C(=O)OCC1CCCC1)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C21H26N2O4/c1-13-16(20(25)27-12-14-7-5-6-8-14)17-15(9-10-21(2,3)26)11-23(4)19(24)18(17)22-13/h11,14,22,26H,5-8,12H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23.7	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346509 ((2-methoxyphenyl)methyl-4-(3-hydroxy-3-methyl-but-...) Show SMILES COc1ccccc1COC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C23H24N2O5/c1-14-18(22(27)30-13-16-8-6-7-9-17(16)29-5)19-15(10-11-23(2,3)28)12-25(4)21(26)20(19)24-14/h6-9,12,24,28H,13H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346515 ((2-fluorophenyl)methyl 4-(3-hydroxy-3-methyl-but-1...) Show SMILES Cc1[nH]c2c(c1C(=O)OCc1ccccc1F)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C22H21FN2O4/c1-13-17(21(27)29-12-15-7-5-6-8-16(15)23)18-14(9-10-22(2,3)28)11-25(4)20(26)19(18)24-13/h5-8,11,24,28H,12H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.7	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346530 ((2-cyano-1,1-dimethyl-ethyl)-4-(3-cyclopropyl-3-hy...) Show SMILES Cc1[nH]c2c(c1C(=O)OC(C)(C)CC#N)c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.8	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346559 ((2-cyano-1,1-dimethyl-ethyl)4-(3-hydroxy-3-methyl-...) Show SMILES Cc1[nH]c2c(c1C(=O)OC(C)(C)CC#N)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C20H23N3O4/c1-12-14(18(25)27-20(4,5)9-10-21)15-13(7-8-19(2,3)26)11-23(6)17(24)16(15)22-12/h11,22,26H,9H2,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27.3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346496 (US10202378, Example 100 | ethyl 2,6-dimethyl-7-oxo...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(O)(c1cccc(c1)-c1cccnc1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27.3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346484 (3-(5-isopropyl-1,3,4-oxadiazol-2-yl)-2,6-dimethyl-...) Show SMILES CC(C)c1nnc(o1)-c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(O)(c1ccccc1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27.6	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346512 (US10202378, Example 116 | [2-(trifluoromethyl)phen...) Show SMILES Cc1[nH]c2c(c1C(=O)OCc1ccccc1C(F)(F)F)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C23H21F3N2O4/c1-13-17(21(30)32-12-15-7-5-6-8-16(15)23(24,25)26)18-14(9-10-22(2,3)31)11-28(4)20(29)19(18)27-13/h5-8,11,27,31H,12H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27.7	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346575 (4-(3-cyclopropyl-3-hydroxy-but-1-ynyl)-3-(5-isobut...) Show SMILES CC(C)Cc1nnc(o1)-c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29.2	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346506 ((2-cyanophenyl)methyl 4-(3-hydroxy-3-methyl-but-1-...) Show SMILES Cc1[nH]c2c(c1C(=O)OCc1ccccc1C#N)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C23H21N3O4/c1-14-18(22(28)30-13-17-8-6-5-7-15(17)11-24)19-16(9-10-23(2,3)29)12-26(4)21(27)20(19)25-14/h5-8,12,25,29H,13H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29.4	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346591 (4-(3-hydroxy-3-methyl-but-1-ynyl)-3-(5-isopropyl-1...) Show SMILES CC(C)c1nnc(o1)-c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C19H22N4O3/c1-10(2)16-21-22-17(26-16)13-11(3)20-15-14(13)12(7-8-19(4,5)25)9-23(6)18(15)24/h9-10,20,25H,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29.4	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346528 (US10202378, Example 132 | isobutyl 4-(3-hydroxy-3-...) Show SMILES CC(C)COC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C19H24N2O4/c1-11(2)10-25-18(23)14-12(3)20-16-15(14)13(7-8-19(4,5)24)9-21(6)17(16)22/h9,11,20,24H,10H2,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29.9	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346404 (US10202378, Example 19 | ethyl 4-[3-(3-cyanophenyl...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)c1cccc(c1)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30.3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346546 (2,2-dimethylpropyl 4-(3-hydroxy-3-methyl-but-1-yny...) Show SMILES Cc1[nH]c2c(c1C(=O)OCC(C)(C)C)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C20H26N2O4/c1-12-14(18(24)26-11-19(2,3)4)15-13(8-9-20(5,6)25)10-22(7)17(23)16(15)21-12/h10,21,25H,11H2,1-7H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30.4	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346490 (4-(3-cyclopropyl-3-hydroxy-but-1-ynyl)-3-[5-[(dime...) Show SMILES CN(C)Cc1nnc(o1)-c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30.8	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346529 (US10202378, Example 133 | tert-butyl 4-(3-hydroxy-...) Show SMILES Cc1[nH]c2c(c1C(=O)OC(C)(C)C)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C19H24N2O4/c1-11-13(17(23)25-18(2,3)4)14-12(8-9-19(5,6)24)10-21(7)16(22)15(14)20-11/h10,20,24H,1-7H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.1	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346562 (2-cyanoethyl 2,6-dimethyl-7-oxo-4-(4,4,4-trifluoro...) Show SMILES Cc1[nH]c2c(c1C(=O)OCCC#N)c(cn(C)c2=O)C#CC(O)(c1ccccc1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.2	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346556 (US10202378, Example 160 | isobutyl 4-(3-hydroxy-3-...) Show SMILES CC(C)COC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32.4	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346476 (US10202378, Example 89 | US10202378, Example 93a |...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(O)(C(F)F)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32.9	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346464 (US10202378, Example 77 | US10202378, Example 92a |...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33.2	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346492 (3-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-4-(3-cyclopr...) Show SMILES Cc1[nH]c2c(c1-c1nnc(o1)C(C)(C)C)c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33.9	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346511 (2-pyridylmethyl 4-(3-hydroxy-3-methyl-but-1-ynyl)-...) Show SMILES Cc1[nH]c2c(c1C(=O)OCc1ccccn1)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C21H21N3O4/c1-13-16(20(26)28-12-15-7-5-6-10-22-15)17-14(8-9-21(2,3)27)11-24(4)19(25)18(17)23-13/h5-7,10-11,23,27H,12H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34.1	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346592 (US10202378, Example 197 | ethyl 4-[3-(3-carbamoylp...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(O)(c1cccc(c1)C(N)=O)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34.1	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346499 (Benzyl 4-(3-hydroxy-3-methyl-but-1-ynyl)-2,6-dimet...) Show SMILES Cc1[nH]c2c(c1C(=O)OCc1ccccc1)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C22H22N2O4/c1-14-17(21(26)28-13-15-8-6-5-7-9-15)18-16(10-11-22(2,3)27)12-24(4)20(25)19(18)23-14/h5-9,12,23,27H,13H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34.5	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346501 (8-quinolylmethyl 4-(3-cyclopropyl-3-hydroxy-but-1-...) Show SMILES Cc1[nH]c2c(c1C(=O)OCc1cccc3cccnc13)c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34.6	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346547 (1,1-dimethylpropyl 4-(3-hydroxy-3-methyl-but-1-yny...) Show SMILES CCC(C)(C)OC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C20H26N2O4/c1-8-20(5,6)26-18(24)14-12(2)21-16-15(14)13(9-10-19(3,4)25)11-22(7)17(16)23/h11,21,25H,8H2,1-7H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35.1	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346430 (US10202378, Example 43 | ethyl 2,6-dimethyl-7-oxo-...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(O)(c1cccc(CO)c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35.5	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346587 (4-(3-cyclopropyl-3-hydroxy-but-1-ynyl)-3-(5-isopro...) Show SMILES CC(C)c1nnc(o1)-c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36.4	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346532 ((2-cyano-1,1-dimethyl-ethyl)2,6-dimethyl-7-oxo-4-(...) Show SMILES Cc1[nH]c2c(c1C(=O)OC(C)(C)CC#N)c(cn(C)c2=O)C#CC(O)(c1ccccc1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36.5	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346555 (US10202378, Example 159 | cyclohexyl 4-(3-hydroxy-...) Show SMILES Cc1[nH]c2c(c1C(=O)OC1CCCCC1)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C21H26N2O4/c1-13-16(20(25)27-15-8-6-5-7-9-15)17-14(10-11-21(2,3)26)12-23(4)19(24)18(17)22-13/h12,15,22,26H,5-9H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36.9	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346502 (US10202378, Example 106 | [3-(hydroxymethyl)phenyl...) Show SMILES Cc1[nH]c2c(c1C(=O)OCc1cccc(CO)c1)c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37.2	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346536 (3-acetamidopropyl 4-(3-cyclopropyl-3-hydroxy-but-1...) Show SMILES CC(=O)NCCCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37.5	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346507 (US10202378, Example 111 | [2-(hydroxymethyl)phenyl...) Show SMILES Cc1[nH]c2c(c1C(=O)OCc1ccccc1CO)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C23H24N2O5/c1-14-18(22(28)30-13-17-8-6-5-7-16(17)12-26)19-15(9-10-23(2,3)29)11-25(4)21(27)20(19)24-14/h5-8,11,24,26,29H,12-13H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37.9	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346447 (US10202378, Example 60 | ethyl 4-[2-(3-aminophenyl...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#Cc1cccc(N)c1 Show InChI InChI=1S/C20H19N3O3/c1-4-26-20(25)16-12(2)22-18-17(16)14(11-23(3)19(18)24)9-8-13-6-5-7-15(21)10-13/h5-7,10-11,22H,4,21H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38.1	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346572 (4-(3-cyclopropyl-3-hydroxy-but-1-ynyl)-2,6-dimethy...) Show SMILES CC(CN1CCOCC1)c1nnc(o1)-c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38.3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346445 (US10202378, Example 58 | ethyl 4-[2-(4-methoxyphen...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#Cc1ccc(OC)cc1 Show InChI InChI=1S/C21H20N2O4/c1-5-27-21(25)17-13(2)22-19-18(17)15(12-23(3)20(19)24)9-6-14-7-10-16(26-4)11-8-14/h7-8,10-12,22H,5H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38.4	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346450 (US10202378, Example 63 | ethyl 4-[2-(3-hydroxyphen...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#Cc1cccc(O)c1 Show InChI InChI=1S/C20H18N2O4/c1-4-26-20(25)16-12(2)21-18-17(16)14(11-22(3)19(18)24)9-8-13-6-5-7-15(23)10-13/h5-7,10-11,21,23H,4H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38.5	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346465 (US10202378, Example 78 | ethyl 4-(3-hydroxy-3-meth...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C17H20N2O4/c1-6-23-16(21)12-10(2)18-14-13(12)11(7-8-17(3,4)22)9-19(5)15(14)20/h9,18,22H,6H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38.5	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346543 (1,1-dimethylbutyl 4-(3-hydroxy-3-methyl-but-1-ynyl...) Show SMILES CCCC(C)(C)OC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C21H28N2O4/c1-8-10-21(5,6)27-19(25)15-13(2)22-17-16(15)14(9-11-20(3,4)26)12-23(7)18(17)24/h12,22,26H,8,10H2,1-7H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38.8	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1504-1635] (Homo sapiens (Human))	BDBM346401 (US10202378, Example 16 | ethyl 4-(3-hydroxy-3-meth...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)Cc1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38.8	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD21504-1635 was cloned, expressed, and purified to homogeneity. TAF1-BD2 binding and inhibition was assessed by monitor...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair

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