Compile Data Set for Download or QSAR

Found 328 hits of ic50 for UniProtKB: P62993   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50064333 (CHEMBL49860 | Phosphoric acid mono-(2-amino-4-{2-a...) Show SMILES NC(Cc1ccc(OP(O)(O)=O)c(N)c1)C(=O)NC1(CCCCC1)C(=O)NC(CC(N)=O)C(N)=O Show InChI InChI=1S/C20H31N6O8P/c21-12-8-11(4-5-15(12)34-35(31,32)33)9-13(22)18(29)26-20(6-2-1-3-7-20)19(30)25-14(17(24)28)10-16(23)27/h4-5,8,13-14H,1-3,6-7,9-10,21-22H2,(H2,23,27)(H2,24,28)(H,25,30)(H,26,29)(H2,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.00400	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of binding to Growth factor receptor bound protein 2 (Grb2) SH2 domain				J Med Chem 41: 1741-4 (1998) Article DOI: 10.1021/jm970856n BindingDB Entry DOI: 10.7270/Q2M32TWK
					More data for this Ligand-Target Pair				3D Structure (docked)
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50073913 (CHEMBL73003 | {4-[(S)-2-Acetylamino-2-(1-{(S)-2-ca...) Show SMILES CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCn1ccc2cc(O)ccc12 Show InChI InChI=1S/C34H45N6O9P/c1-22(41)37-27(18-23-6-8-24(9-7-23)21-50(47,48)49)32(45)39-34(13-3-2-4-14-34)33(46)38-28(20-30(35)43)31(44)36-15-5-16-40-17-12-25-19-26(42)10-11-29(25)40/h6-12,17,19,27-28,42H,2-5,13-16,18,20-21H2,1H3,(H2,35,43)(H,36,44)(H,37,41)(H,38,46)(H,39,45)(H2,47,48,49)/t27-,28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptor				Bioorg Med Chem Lett 9: 221-6 (1999) BindingDB Entry DOI: 10.7270/Q2N58KJG
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50073909 (CHEMBL72036 | {4-[(S)-2-Acetylamino-2-(1-{(S)-2-ca...) Show SMILES CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCn1ccc2cc(C)ccc12 Show InChI InChI=1S/C35H47N6O8P/c1-23-7-12-30-27(19-23)13-18-41(30)17-6-16-37-32(44)29(21-31(36)43)39-34(46)35(14-4-3-5-15-35)40-33(45)28(38-24(2)42)20-25-8-10-26(11-9-25)22-50(47,48)49/h7-13,18-19,28-29H,3-6,14-17,20-22H2,1-2H3,(H2,36,43)(H,37,44)(H,38,42)(H,39,46)(H,40,45)(H2,47,48,49)/t28-,29-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptor				Bioorg Med Chem Lett 9: 221-6 (1999) BindingDB Entry DOI: 10.7270/Q2N58KJG
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50073917 (CHEMBL72694 | {4-[(S)-2-Acetylamino-2-(1-{(S)-2-ca...) Show SMILES COc1ccc2n(CCCNC(=O)[C@H](CC(N)=O)NC(=O)C3(CCCCC3)NC(=O)[C@H](Cc3ccc(CP(O)(O)=O)cc3)NC(C)=O)ccc2c1 Show InChI InChI=1S/C35H47N6O9P/c1-23(42)38-28(19-24-7-9-25(10-8-24)22-51(47,48)49)33(45)40-35(14-4-3-5-15-35)34(46)39-29(21-31(36)43)32(44)37-16-6-17-41-18-13-26-20-27(50-2)11-12-30(26)41/h7-13,18,20,28-29H,3-6,14-17,19,21-22H2,1-2H3,(H2,36,43)(H,37,44)(H,38,42)(H,39,46)(H,40,45)(H2,47,48,49)/t28-,29-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptor				Bioorg Med Chem Lett 9: 221-6 (1999) BindingDB Entry DOI: 10.7270/Q2N58KJG
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50064333 (CHEMBL49860 | Phosphoric acid mono-(2-amino-4-{2-a...) Show SMILES NC(Cc1ccc(OP(O)(O)=O)c(N)c1)C(=O)NC1(CCCCC1)C(=O)NC(CC(N)=O)C(N)=O Show InChI InChI=1S/C20H31N6O8P/c21-12-8-11(4-5-15(12)34-35(31,32)33)9-13(22)18(29)26-20(6-2-1-3-7-20)19(30)25-14(17(24)28)10-16(23)27/h4-5,8,13-14H,1-3,6-7,9-10,21-22H2,(H2,23,27)(H2,24,28)(H,25,30)(H,26,29)(H2,31,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of binding to Grb2 SH2 domain				J Med Chem 41: 1741-4 (1998) Article DOI: 10.1021/jm970856n BindingDB Entry DOI: 10.7270/Q2M32TWK
					More data for this Ligand-Target Pair				3D Structure (docked)
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50078348 (CHEMBL77689 | [(S)-1-[1-((S)-1,2-Dicarbamoyl-ethyl...) Show SMILES NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(N)=O Show InChI InChI=1S/C28H37N6O10P/c29-19-6-4-5-18(13-19)16-43-27(39)33-22(14-17-7-9-20(10-8-17)44-45(40,41)42)25(37)34-28(11-2-1-3-12-28)26(38)32-21(24(31)36)15-23(30)35/h4-10,13,21-22H,1-3,11-12,14-16,29H2,(H2,30,35)(H2,31,36)(H,32,38)(H,33,39)(H,34,37)(H2,40,41,42)/t21-,22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas Curated by ChEMBL					Assay Description Binding affinity to Grb2 SH2 domain (unknown origin)				Bioorg Med Chem Lett 24: 3164-7 (2014) Article DOI: 10.1016/j.bmcl.2014.04.114 BindingDB Entry DOI: 10.7270/Q2SN0CZD
					More data for this Ligand-Target Pair				3D Structure (docked)
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50078348 (CHEMBL77689 | [(S)-1-[1-((S)-1,2-Dicarbamoyl-ethyl...) Show SMILES NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(N)=O Show InChI InChI=1S/C28H37N6O10P/c29-19-6-4-5-18(13-19)16-43-27(39)33-22(14-17-7-9-20(10-8-17)44-45(40,41)42)25(37)34-28(11-2-1-3-12-28)26(38)32-21(24(31)36)15-23(30)35/h4-10,13,21-22H,1-3,11-12,14-16,29H2,(H2,30,35)(H2,31,36)(H,32,38)(H,33,39)(H,34,37)(H2,40,41,42)/t21-,22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of Grb2-SH2 domain binding to phospho-EGF receptor intracellular C-terminal domain				J Med Chem 42: 2358-63 (1999) Article DOI: 10.1021/jm991013u BindingDB Entry DOI: 10.7270/Q2S181PH
					More data for this Ligand-Target Pair				3D Structure (docked)
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50073918 (CHEMBL431982 | [4-((S)-2-Acetylamino-2-{1-[(S)-2-c...) Show SMILES CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCn1ccc2ccccc12 Show InChI InChI=1S/C34H45N6O8P/c1-23(41)37-27(20-24-10-12-25(13-11-24)22-49(46,47)48)32(44)39-34(15-5-2-6-16-34)33(45)38-28(21-30(35)42)31(43)36-17-7-18-40-19-14-26-8-3-4-9-29(26)40/h3-4,8-14,19,27-28H,2,5-7,15-18,20-22H2,1H3,(H2,35,42)(H,36,43)(H,37,41)(H,38,45)(H,39,44)(H2,46,47,48)/t27-,28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptor				Bioorg Med Chem Lett 9: 221-6 (1999) BindingDB Entry DOI: 10.7270/Q2N58KJG
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50139763 (CHEMBL306657 | [(E)-(9S,10S,14S,18S)-18-Carbamoylm...) Show SMILES NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(CP(O)(O)=O)cc1 |t:24| Show InChI InChI=1S/C39H47N4O9P/c40-34(44)22-33-37(48)41-23-26(20-29-11-7-10-27-9-2-3-12-30(27)29)8-6-13-31(28-16-14-25(15-17-28)24-53(50,51)52)32(21-35(45)46)36(47)43-39(38(49)42-33)18-4-1-5-19-39/h2-3,6-7,9-17,26,31-33H,1,4-5,8,18-24H2,(H2,40,44)(H,41,48)(H,42,49)(H,43,47)(H,45,46)(H2,50,51,52)/b13-6+/t26-,31+,32-,33-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description In vitro Growth factor receptor bound protein 2-binding affinity of the compound was determined in in surface plasmon resonance (SPR) method				J Med Chem 47: 2166-9 (2004) Article DOI: 10.1021/jm030510e BindingDB Entry DOI: 10.7270/Q2668CNN
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50139763 (CHEMBL306657 | [(E)-(9S,10S,14S,18S)-18-Carbamoylm...) Show SMILES NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(CP(O)(O)=O)cc1 |t:24| Show InChI InChI=1S/C39H47N4O9P/c40-34(44)22-33-37(48)41-23-26(20-29-11-7-10-27-9-2-3-12-30(27)29)8-6-13-31(28-16-14-25(15-17-28)24-53(50,51)52)32(21-35(45)46)36(47)43-39(38(49)42-33)18-4-1-5-19-39/h2-3,6-7,9-17,26,31-33H,1,4-5,8,18-24H2,(H2,40,44)(H,41,48)(H,42,49)(H,43,47)(H,45,46)(H2,50,51,52)/b13-6+/t26-,31+,32-,33-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description In vitro Growth factor receptor bound protein 2-binding affinity of the compound was determined in in surface plasmon resonance (SPR) method				J Med Chem 47: 2166-9 (2004) Article DOI: 10.1021/jm030510e BindingDB Entry DOI: 10.7270/Q2668CNN
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50078347 (CHEMBL307890 | [(S)-1-[1-((1R,6S)-6-Carbamoyl-cycl...) Show SMILES NC(=O)[C@H]1CCC=C[C@H]1NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1 |c:6| Show InChI InChI=1S/C31H40N5O9P/c32-22-8-6-7-21(17-22)19-44-30(40)35-26(18-20-11-13-23(14-12-20)45-46(41,42)43)28(38)36-31(15-4-1-5-16-31)29(39)34-25-10-3-2-9-24(25)27(33)37/h3,6-8,10-14,17,24-26H,1-2,4-5,9,15-16,18-19,32H2,(H2,33,37)(H,34,39)(H,35,40)(H,36,38)(H2,41,42,43)/t24-,25+,26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG MMDB PC cid PC sid UniChem Similars	MMDB PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Grb2-SH2 domain binding to phospho-EGF receptor intracellular C-terminal domain				J Med Chem 45: 1543-58 (2002) BindingDB Entry DOI: 10.7270/Q2CN74ND
					More data for this Ligand-Target Pair				3D Structure (docked)
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50078347 (CHEMBL307890 | [(S)-1-[1-((1R,6S)-6-Carbamoyl-cycl...) Show SMILES NC(=O)[C@H]1CCC=C[C@H]1NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1 |c:6| Show InChI InChI=1S/C31H40N5O9P/c32-22-8-6-7-21(17-22)19-44-30(40)35-26(18-20-11-13-23(14-12-20)45-46(41,42)43)28(38)36-31(15-4-1-5-16-31)29(39)34-25-10-3-2-9-24(25)27(33)37/h3,6-8,10-14,17,24-26H,1-2,4-5,9,15-16,18-19,32H2,(H2,33,37)(H,34,39)(H,35,40)(H,36,38)(H2,41,42,43)/t24-,25+,26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG MMDB PC cid PC sid UniChem Similars	MMDB Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of Grb2-SH2 domain binding to phospho-EGF receptor intracellular C-terminal domain				J Med Chem 42: 2358-63 (1999) Article DOI: 10.1021/jm991013u BindingDB Entry DOI: 10.7270/Q2S181PH
					More data for this Ligand-Target Pair				3D Structure (docked)
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50124296 (12-benzyl-36-carbamoylmethyl-9-(4-phosphonooxybenz...) Show SMILES CC(C)[C@@H]1NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](C)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)(C)C)NC(=O)CNC1=O)C(N)=O Show InChI InChI=1S/C60H83N12O17PS/c1-33(2)49-57(84)63-30-47(75)65-44(29-59(4,5)6)55(82)67-41(26-36-15-19-38(73)20-16-36)53(80)69-45(50(62)77)31-91-32-48(76)64-34(3)51(78)66-40(25-35-13-9-7-10-14-35)52(79)68-42(27-37-17-21-39(22-18-37)89-90(86,87)88)56(83)72-60(23-11-8-12-24-60)58(85)70-43(28-46(61)74)54(81)71-49/h7,9-10,13-22,33-34,40-45,49,73H,8,11-12,23-32H2,1-6H3,(H2,61,74)(H2,62,77)(H,63,84)(H,64,76)(H,65,75)(H,66,78)(H,67,82)(H,68,79)(H,69,80)(H,70,85)(H,71,81)(H,72,83)(H2,86,87,88)/t34-,40-,41-,42-,43-,44-,45-,49-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibition of Growth factor receptor-bound protein 2 (Grb2) SH2 domain binding by ELISA				Bioorg Med Chem Lett 13: 895-9 (2003) BindingDB Entry DOI: 10.7270/Q2SF2VH2
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50122796 (CHEMBL84798 | [18-Carbamoylmethyl-14-(2,3-dihydro-...) Show SMILES NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C[C@@H](CC2=c3ccccc3=CCC2)CNC1=O)c1ccc(CP(O)(O)=O)cc1 |c:29,36,t:24| Show InChI InChI=1S/C39H49N4O9P/c40-34(44)22-33-37(48)41-23-26(20-29-11-7-10-27-9-2-3-12-30(27)29)8-6-13-31(28-16-14-25(15-17-28)24-53(50,51)52)32(21-35(45)46)36(47)43-39(38(49)42-33)18-4-1-5-19-39/h2-3,6,9-10,12-17,26,31-33H,1,4-5,7-8,11,18-24H2,(H2,40,44)(H,41,48)(H,42,49)(H,43,47)(H,45,46)(H2,50,51,52)/b13-6+/t26-,31+,32-,33-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute-Frederick Curated by ChEMBL					Assay Description Inhibition against Growth factor receptor bound protein 2 binding using ELISA technique				J Med Chem 46: 244-54 (2003) Article DOI: 10.1021/jm0203635 BindingDB Entry DOI: 10.7270/Q2RR1XMN
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50139763 (CHEMBL306657 | [(E)-(9S,10S,14S,18S)-18-Carbamoylm...) Show SMILES NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(CP(O)(O)=O)cc1 |t:24| Show InChI InChI=1S/C39H47N4O9P/c40-34(44)22-33-37(48)41-23-26(20-29-11-7-10-27-9-2-3-12-30(27)29)8-6-13-31(28-16-14-25(15-17-28)24-53(50,51)52)32(21-35(45)46)36(47)43-39(38(49)42-33)18-4-1-5-19-39/h2-3,6-7,9-17,26,31-33H,1,4-5,8,18-24H2,(H2,40,44)(H,41,48)(H,42,49)(H,43,47)(H,45,46)(H2,50,51,52)/b13-6+/t26-,31+,32-,33-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description In vitro binding affinity in extracellular ELISA-based assay for Grb2 SH2 domain				J Med Chem 47: 788-91 (2004) Article DOI: 10.1021/jm030440b BindingDB Entry DOI: 10.7270/Q2XD114Q
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50085869 (CHEMBL367037 | N-[1-(1-{2-Carbamoyl-1-[3-(5-methyl...) Show SMILES Cc1ccc2n(CCCNC(=O)[C@H](CC(N)=O)NC(=O)C3(CCCCC3)NC(=O)[C@H](Cc3ccc(CP(O)(O)=O)cc3)NC(=O)C(O)=O)ccc2c1 Show InChI InChI=1S/C35H45N6O10P/c1-22-6-11-28-25(18-22)12-17-41(28)16-5-15-37-30(43)27(20-29(36)42)39-34(48)35(13-3-2-4-14-35)40-31(44)26(38-32(45)33(46)47)19-23-7-9-24(10-8-23)21-52(49,50)51/h6-12,17-18,26-27H,2-5,13-16,19-21H2,1H3,(H2,36,42)(H,37,43)(H,38,45)(H,39,48)(H,40,44)(H,46,47)(H2,49,50,51)/t26-,27-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibition of Growth factor receptor bound protein 2 binding by ELISA assay method				J Med Chem 43: 911-20 (2000) BindingDB Entry DOI: 10.7270/Q2WD3ZRD
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50139763 (CHEMBL306657 | [(E)-(9S,10S,14S,18S)-18-Carbamoylm...) Show SMILES NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(CP(O)(O)=O)cc1 |t:24| Show InChI InChI=1S/C39H47N4O9P/c40-34(44)22-33-37(48)41-23-26(20-29-11-7-10-27-9-2-3-12-30(27)29)8-6-13-31(28-16-14-25(15-17-28)24-53(50,51)52)32(21-35(45)46)36(47)43-39(38(49)42-33)18-4-1-5-19-39/h2-3,6-7,9-17,26,31-33H,1,4-5,8,18-24H2,(H2,40,44)(H,41,48)(H,42,49)(H,43,47)(H,45,46)(H2,50,51,52)/b13-6+/t26-,31+,32-,33-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of GST-fused Grb2-SH2 domain (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128354 BindingDB Entry DOI: 10.7270/Q2CR5Z6S
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50168312 (2-{4-[(16R,20S)-18-((S)-Carbamoylmethyl)-9-carboxy...) Show SMILES Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(cc3)C(C(O)=O)C(O)=O)ccc2c1 |t:36| Show InChI InChI=1S/C40H47N5O10/c1-23-8-13-31-27(18-23)14-17-45(31)22-24-6-5-7-28(25-9-11-26(12-10-25)34(37(51)52)38(53)54)29(19-33(47)48)35(49)44-40(15-3-2-4-16-40)39(55)43-30(20-32(41)46)36(50)42-21-24/h5,7-14,17-18,24,28-30,34H,2-4,6,15-16,19-22H2,1H3,(H2,41,46)(H,42,50)(H,43,55)(H,44,49)(H,47,48)(H,51,52)(H,53,54)/b7-5+/t24-,28-,29+,30+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibitory concentration against growth factor receptor bound protein 2				J Med Chem 48: 3945-8 (2005) Article DOI: 10.1021/jm050059m BindingDB Entry DOI: 10.7270/Q2V69J48
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50073911 (CHEMBL72525 | {4-[(S)-2-Acetylamino-2-(1-{(S)-2-ca...) Show SMILES CN(C)c1ccc2n(CCCNC(=O)[C@H](CC(N)=O)NC(=O)C3(CCCCC3)NC(=O)[C@H](Cc3ccc(CP(O)(O)=O)cc3)NC(C)=O)ccc2c1 Show InChI InChI=1S/C36H50N7O8P/c1-24(44)39-29(20-25-8-10-26(11-9-25)23-52(49,50)51)34(47)41-36(15-5-4-6-16-36)35(48)40-30(22-32(37)45)33(46)38-17-7-18-43-19-14-27-21-28(42(2)3)12-13-31(27)43/h8-14,19,21,29-30H,4-7,15-18,20,22-23H2,1-3H3,(H2,37,45)(H,38,46)(H,39,44)(H,40,48)(H,41,47)(H2,49,50,51)/t29-,30-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptor				Bioorg Med Chem Lett 9: 221-6 (1999) BindingDB Entry DOI: 10.7270/Q2N58KJG
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50124301 (2-[9-(4-phosphonooxybenzyl)-21-carbamoyl-24-(4-hyd...) Show SMILES CSCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C Show InChI InChI=1S/C55H81N12O17PS2/c1-29(2)22-37-49(75)63-39(24-33-12-16-35(17-13-33)84-85(81,82)83)52(78)67-55(19-8-7-9-20-55)54(80)65-40(25-42(56)69)51(77)66-45(30(3)4)53(79)58-26-43(70)60-36(18-21-86-6)48(74)62-38(23-32-10-14-34(68)15-11-32)50(76)64-41(46(57)72)27-87-28-44(71)59-31(5)47(73)61-37/h10-17,29-31,36-41,45,68H,7-9,18-28H2,1-6H3,(H2,56,69)(H2,57,72)(H,58,79)(H,59,71)(H,60,70)(H,61,73)(H,62,74)(H,63,75)(H,64,76)(H,65,80)(H,66,77)(H,67,78)(H2,81,82,83)/t31-,36-,37-,38-,39-,40-,41-,45-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibition of Growth factor receptor-bound protein 2 (Grb2) SH2 domain binding by ELISA				Bioorg Med Chem Lett 13: 895-9 (2003) BindingDB Entry DOI: 10.7270/Q2SF2VH2
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50073909 (CHEMBL72036 | {4-[(S)-2-Acetylamino-2-(1-{(S)-2-ca...) Show SMILES CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCn1ccc2cc(C)ccc12 Show InChI InChI=1S/C35H47N6O8P/c1-23-7-12-30-27(19-23)13-18-41(30)17-6-16-37-32(44)29(21-31(36)43)39-34(46)35(14-4-3-5-15-35)40-33(45)28(38-24(2)42)20-25-8-10-26(11-9-25)22-50(47,48)49/h7-13,18-19,28-29H,3-6,14-17,20-22H2,1-2H3,(H2,36,43)(H,37,44)(H,38,42)(H,39,46)(H,40,45)(H2,47,48,49)/t28-,29-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibition of Growth factor receptor bound protein 2 binding by ELISA assay method				J Med Chem 43: 911-20 (2000) BindingDB Entry DOI: 10.7270/Q2WD3ZRD
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50580855 (CHEMBL1205233) Show SMILES NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(cc1)C(C(O)=O)C(O)=O |t:24| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to Grb2-SH2 domain (unknown origin) by ELISA				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128354 BindingDB Entry DOI: 10.7270/Q2CR5Z6S
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50143944 (2-[4-((E)-(9S,10S,14S,18S)-18-Carbamoylmethyl-9-ca...) Show SMILES NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(cc1)C(C([O-])=O)C([O-])=O |t:24| Show InChI InChI=1S/C41H46N4O10/c42-33(46)22-32-37(50)43-23-24(20-28-11-7-10-25-9-2-3-12-29(25)28)8-6-13-30(26-14-16-27(17-15-26)35(38(51)52)39(53)54)31(21-34(47)48)36(49)45-41(40(55)44-32)18-4-1-5-19-41/h2-3,6-7,9-17,24,30-32,35H,1,4-5,8,18-23H2,(H2,42,46)(H,43,50)(H,44,55)(H,45,49)(H,47,48)(H,51,52)(H,53,54)/p-2/b13-6+/t24-,30+,31-,32-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description In vitro Growth factor receptor bound protein 2-binding affinity of the compound was determined in ELISA method				J Med Chem 47: 2166-9 (2004) Article DOI: 10.1021/jm030510e BindingDB Entry DOI: 10.7270/Q2668CNN
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50168318 (CHEMBL424823 | [(15R,20S)-18-Carbamoylmethyl-10-[4...) Show SMILES Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(CP(C)(O)=O)cc3)ccc2c1 |t:36| Show InChI InChI=1S/C39H50N5O8P/c1-25-9-14-33-29(19-25)15-18-44(33)23-27-7-6-8-30(28-12-10-26(11-13-28)24-53(2,51)52)31(20-35(46)47)36(48)43-39(16-4-3-5-17-39)38(50)42-32(21-34(40)45)37(49)41-22-27/h6,8-15,18-19,27,30-32H,3-5,7,16-17,20-24H2,1-2H3,(H2,40,45)(H,41,49)(H,42,50)(H,43,48)(H,46,47)(H,51,52)/b8-6+/t27-,30-,31+,32+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibitory concentration against growth factor receptor bound protein 2				J Med Chem 48: 3945-8 (2005) Article DOI: 10.1021/jm050059m BindingDB Entry DOI: 10.7270/Q2V69J48
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50075017 (CHEMBL332862 | Phosphoric acid mono-[4-((R)-2-acet...) Show SMILES CC(=O)N[C@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cccc2ccccc12 Show InChI InChI=1S/C35H44N5O9P/c1-23(41)38-29(21-24-14-16-27(17-15-24)49-50(46,47)48)33(44)40-35(18-5-2-6-19-35)34(45)39-30(22-31(36)42)32(43)37-20-8-12-26-11-7-10-25-9-3-4-13-28(25)26/h3-4,7,9-11,13-17,29-30H,2,5-6,8,12,18-22H2,1H3,(H2,36,42)(H,37,43)(H,38,41)(H,39,45)(H,40,44)(H2,46,47,48)/t29-,30+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against Growth factor receptor bound protein 2 in MDA-MB-453 cells				Bioorg Med Chem Lett 9: 347-52 (1999) BindingDB Entry DOI: 10.7270/Q2VM4BF2
					More data for this Ligand-Target Pair				3D Structure (docked)
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50124293 (2-[6'-(4-phosphonooxybenzyl)-27'-carbamoyl-24'-(4-...) Show SMILES [H][C@@]12CCCN1C(=O)CSC[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(C)(C)C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)[C@H](CC(C)C)NC2=O)C(C)C)C(N)=O Show InChI InChI=1S/C59H87N12O17PS/c1-32(2)24-38-50(77)65-40(26-35-15-19-37(20-16-35)88-89(85,86)87)54(81)70-59(21-9-8-10-22-59)57(84)68-41(27-45(60)73)52(79)69-48(33(3)4)56(83)62-29-46(74)63-42(28-58(5,6)7)53(80)64-39(25-34-13-17-36(72)18-14-34)51(78)67-43(49(61)76)30-90-31-47(75)71-23-11-12-44(71)55(82)66-38/h13-20,32-33,38-44,48,72H,8-12,21-31H2,1-7H3,(H2,60,73)(H2,61,76)(H,62,83)(H,63,74)(H,64,80)(H,65,77)(H,66,82)(H,67,78)(H,68,84)(H,69,79)(H,70,81)(H2,85,86,87)/t38-,39-,40-,41-,42-,43-,44-,48-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibition of Growth factor receptor-bound protein 2 (Grb2) SH2 domain binding by ELISA				Bioorg Med Chem Lett 13: 895-9 (2003) BindingDB Entry DOI: 10.7270/Q2SF2VH2
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50336688 (CHEMBL1672710 | N2-{[1-({(2R)-2-carboxymethyl-3-[4...) Show SMILES OC(=O)C[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(O)=O)C(=O)NCCCc1cccc2ccccc12 |r| Show InChI InChI=1S/C36H44N3O10P/c40-31(41)21-28(20-24-13-15-25(16-14-24)23-50(47,48)49)33(44)39-36(17-4-1-5-18-36)35(46)38-30(22-32(42)43)34(45)37-19-7-11-27-10-6-9-26-8-2-3-12-29(26)27/h2-3,6,8-10,12-16,28,30H,1,4-5,7,11,17-23H2,(H,37,45)(H,38,46)(H,39,44)(H,40,41)(H,42,43)(H2,47,48,49)/t28-,30+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense de Madrid Curated by ChEMBL					Assay Description Displacement of biotin-Ahx-PSpYVNVQN from Grb2-SH2 by competition binding assay				J Med Chem 54: 1096-100 (2011) Article DOI: 10.1021/jm101478n BindingDB Entry DOI: 10.7270/Q20002CC
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50085874 (2-{4-[(S)-2-(1-{(S)-2-Carbamoyl-1-[3-(5-methyl-ind...) Show SMILES Cc1ccc2n(CCCNC(=O)[C@H](CC(N)=O)NC(=O)C3(CCCCC3)NC(=O)[C@H](Cc3ccc(cc3)C(C(O)=O)C(O)=O)NC(=O)C(O)=O)ccc2c1 Show InChI InChI=1S/C37H44N6O11/c1-21-6-11-27-24(18-21)12-17-43(27)16-5-15-39-30(45)26(20-28(38)44)41-36(54)37(13-3-2-4-14-37)42-31(46)25(40-32(47)35(52)53)19-22-7-9-23(10-8-22)29(33(48)49)34(50)51/h6-12,17-18,25-26,29H,2-5,13-16,19-20H2,1H3,(H2,38,44)(H,39,45)(H,40,47)(H,41,54)(H,42,46)(H,48,49)(H,50,51)(H,52,53)/t25-,26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibition of Growth factor receptor bound protein 2 binding by ELISA assay method				J Med Chem 43: 911-20 (2000) BindingDB Entry DOI: 10.7270/Q2WD3ZRD
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50085874 (2-{4-[(S)-2-(1-{(S)-2-Carbamoyl-1-[3-(5-methyl-ind...) Show SMILES Cc1ccc2n(CCCNC(=O)[C@H](CC(N)=O)NC(=O)C3(CCCCC3)NC(=O)[C@H](Cc3ccc(cc3)C(C(O)=O)C(O)=O)NC(=O)C(O)=O)ccc2c1 Show InChI InChI=1S/C37H44N6O11/c1-21-6-11-27-24(18-21)12-17-43(27)16-5-15-39-30(45)26(20-28(38)44)41-36(54)37(13-3-2-4-14-37)42-31(46)25(40-32(47)35(52)53)19-22-7-9-23(10-8-22)29(33(48)49)34(50)51/h6-12,17-18,25-26,29H,2-5,13-16,19-20H2,1H3,(H2,38,44)(H,39,45)(H,40,47)(H,41,54)(H,42,46)(H,48,49)(H,50,51)(H,52,53)/t25-,26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description Inhibitory concentration required against Src homology (SH2) domain of Growth factor receptor bound protein 2 by ELISA binding assay				Bioorg Med Chem Lett 11: 1201-3 (2001) BindingDB Entry DOI: 10.7270/Q2G1603X
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50122792 (CHEMBL312875 | [3-Carbamoylmethyl-14-(2,3-dihydro-...) Show SMILES CC1(C)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C[C@@H](CC2=c3ccccc3=CCC2)CNC(=O)[C@H](CC(N)=O)NC1=O)c1ccc(CP(O)(O)=O)cc1 |c:17,24,t:12| Show InChI InChI=1S/C36H45N4O9P/c1-36(2)35(46)39-30(19-31(37)41)34(45)38-20-23(17-26-10-6-9-24-8-3-4-11-27(24)26)7-5-12-28(29(18-32(42)43)33(44)40-36)25-15-13-22(14-16-25)21-50(47,48)49/h3-5,8-9,11-16,23,28-30H,6-7,10,17-21H2,1-2H3,(H2,37,41)(H,38,45)(H,39,46)(H,40,44)(H,42,43)(H2,47,48,49)/b12-5+/t23-,28+,29-,30-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute-Frederick Curated by ChEMBL					Assay Description Inhibition against Growth factor receptor bound protein 2 binding using ELISA technique				J Med Chem 46: 244-54 (2003) Article DOI: 10.1021/jm0203635 BindingDB Entry DOI: 10.7270/Q2RR1XMN
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50118687 ((R)-N-{1-[(S)-2-Carbamoyl-1-(3-naphthalen-1-yl-pro...) Show SMILES NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@@H](CC(O)=O)Cc1ccc(CP(O)(O)=O)cc1)C(=O)NCCCc1cccc2ccccc12 Show InChI InChI=1S/C36H45N4O9P/c37-31(41)22-30(34(45)38-19-7-11-27-10-6-9-26-8-2-3-12-29(26)27)39-35(46)36(17-4-1-5-18-36)40-33(44)28(21-32(42)43)20-24-13-15-25(16-14-24)23-50(47,48)49/h2-3,6,8-10,12-16,28,30H,1,4-5,7,11,17-23H2,(H2,37,41)(H,38,45)(H,39,46)(H,40,44)(H,42,43)(H2,47,48,49)/t28-,30+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 3 receptor				Bioorg Med Chem Lett 12: 2781-4 (2002) BindingDB Entry DOI: 10.7270/Q23R0S6B
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50124291 (3-[17-carbamoyl-32-carbamoylmethyl-20-(4-hydroxybe...) Show SMILES CSCC[C@@H]1NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC(=O)[C@H](CC(C)C)NC(=O)CCNC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)C(C)C Show InChI InChI=1S/C53H77N12O19PS2/c1-27(2)20-35-49(76)62-36(22-30-8-12-32(13-9-30)84-85(81,82)83)50(77)60-33(14-15-44(71)72)47(74)63-38(23-40(54)67)52(79)65-45(28(3)4)53(80)57-24-42(69)58-34(17-19-86-5)48(75)61-37(21-29-6-10-31(66)11-7-29)51(78)64-39(46(55)73)25-87-26-43(70)56-18-16-41(68)59-35/h6-13,27-28,33-39,45,66H,14-26H2,1-5H3,(H2,54,67)(H2,55,73)(H,56,70)(H,57,80)(H,58,69)(H,59,68)(H,60,77)(H,61,75)(H,62,76)(H,63,74)(H,64,78)(H,65,79)(H,71,72)(H2,81,82,83)/t33-,34-,35-,36-,37-,38-,39-,45-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibition of Growth factor receptor-bound protein 2 (Grb2) SH2 domain binding by ELISA				Bioorg Med Chem Lett 13: 895-9 (2003) BindingDB Entry DOI: 10.7270/Q2SF2VH2
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50168317 (CHEMBL193281 | [(15R,20S)-10-[4-(Benzyl-hydroxy-ph...) Show SMILES Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(CP(O)(=O)Cc4ccccc4)cc3)ccc2c1 |t:36| Show InChI InChI=1S/C45H54N5O8P/c1-30-13-18-39-35(23-30)19-22-50(39)27-33-11-8-12-36(34-16-14-32(15-17-34)29-59(57,58)28-31-9-4-2-5-10-31)37(24-41(52)53)42(54)49-45(20-6-3-7-21-45)44(56)48-38(25-40(46)51)43(55)47-26-33/h2,4-5,8-10,12-19,22-23,33,36-38H,3,6-7,11,20-21,24-29H2,1H3,(H2,46,51)(H,47,55)(H,48,56)(H,49,54)(H,52,53)(H,57,58)/b12-8+/t33-,36-,37+,38+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibitory concentration against growth factor receptor bound protein 2				J Med Chem 48: 3945-8 (2005) Article DOI: 10.1021/jm050059m BindingDB Entry DOI: 10.7270/Q2V69J48
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50168316 (CHEMBL263328 | N-{4-[(7S,14R,18S)-18-Carbamoylmeth...) Show SMILES Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(NC(=O)C(O)=O)cc3)ccc2c1 |t:36| Show InChI InChI=1S/C39H46N6O9/c1-23-8-13-31-26(18-23)14-17-45(31)22-24-6-5-7-28(25-9-11-27(12-10-25)42-36(51)37(52)53)29(19-33(47)48)34(49)44-39(15-3-2-4-16-39)38(54)43-30(20-32(40)46)35(50)41-21-24/h5,7-14,17-18,24,28-30H,2-4,6,15-16,19-22H2,1H3,(H2,40,46)(H,41,50)(H,42,51)(H,43,54)(H,44,49)(H,47,48)(H,52,53)/b7-5+/t24-,28-,29+,30+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibitory concentration against growth factor receptor bound protein 2				J Med Chem 48: 3945-8 (2005) Article DOI: 10.1021/jm050059m BindingDB Entry DOI: 10.7270/Q2V69J48
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50072865 (CHEMBL55627 | N-[(S)-1-{1-[(S)-2-Carbamoyl-1-(3-na...) Show SMILES NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(CP(O)(O)=O)cc1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 Show InChI InChI=1S/C36H44N5O10P/c37-30(42)21-29(31(43)38-19-7-11-26-10-6-9-25-8-2-3-12-27(25)26)40-35(48)36(17-4-1-5-18-36)41-32(44)28(39-33(45)34(46)47)20-23-13-15-24(16-14-23)22-52(49,50)51/h2-3,6,8-10,12-16,28-29H,1,4-5,7,11,17-22H2,(H2,37,42)(H,38,43)(H,39,45)(H,40,48)(H,41,44)(H,46,47)(H2,49,50,51)/t28-,29-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
National Institutes of Health Curated by ChEMBL					Assay Description Binding affinity for Growth factor receptor bound protein 2 SH2 domain				Bioorg Med Chem Lett 12: 2781-4 (2002) BindingDB Entry DOI: 10.7270/Q23R0S6B
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50073912 (CHEMBL72996 | {4-[(S)-2-Acetylamino-2-(1-{(S)-2-ca...) Show SMILES CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1cn(C)c2ccccc12 Show InChI InChI=1S/C35H47N6O8P/c1-23(42)38-28(19-24-12-14-25(15-13-24)22-50(47,48)49)33(45)40-35(16-6-3-7-17-35)34(46)39-29(20-31(36)43)32(44)37-18-8-9-26-21-41(2)30-11-5-4-10-27(26)30/h4-5,10-15,21,28-29H,3,6-9,16-20,22H2,1-2H3,(H2,36,43)(H,37,44)(H,38,42)(H,39,46)(H,40,45)(H2,47,48,49)/t28-,29-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptor				Bioorg Med Chem Lett 9: 221-6 (1999) BindingDB Entry DOI: 10.7270/Q2N58KJG
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50072865 (CHEMBL55627 | N-[(S)-1-{1-[(S)-2-Carbamoyl-1-(3-na...) Show SMILES NC(=O)C[C@H](NC(=O)C1(CCCCC1)NC(=O)[C@H](Cc1ccc(CP(O)(O)=O)cc1)NC(=O)C(O)=O)C(=O)NCCCc1cccc2ccccc12 Show InChI InChI=1S/C36H44N5O10P/c37-30(42)21-29(31(43)38-19-7-11-26-10-6-9-25-8-2-3-12-27(25)26)40-35(48)36(17-4-1-5-18-36)41-32(44)28(39-33(45)34(46)47)20-23-13-15-24(16-14-23)22-52(49,50)51/h2-3,6,8-10,12-16,28-29H,1,4-5,7,11,17-22H2,(H2,37,42)(H,38,43)(H,39,45)(H,40,48)(H,41,44)(H,46,47)(H2,49,50,51)/t28-,29-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description In vitro Growth factor receptor bound protein 2-binding affinity of the compound was determined in ELISA method				J Med Chem 47: 2166-9 (2004) Article DOI: 10.1021/jm030510e BindingDB Entry DOI: 10.7270/Q2668CNN
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50080832 (CHEMBL334099 | [1-[1-(1,2-Dicarbamoyl-ethylcarbamo...) Show SMILES CC(Cc1ccc(OP(O)(O)=O)cc1)(NC(=O)C(Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)C(=O)NC(CC(N)=O)C(N)=O Show InChI InChI=1S/C31H38N6O14P2/c1-31(29(41)35-24(27(34)39)15-26(33)38,16-19-7-11-23(12-8-19)51-53(46,47)48)37-28(40)25(14-18-5-9-22(10-6-18)50-52(43,44)45)36-30(42)49-17-20-3-2-4-21(32)13-20/h2-13,24-25H,14-17,32H2,1H3,(H2,33,38)(H2,34,39)(H,35,41)(H,36,42)(H,37,40)(H2,43,44,45)(H2,46,47,48)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description The compound was evaluated for its potency to inhibit the interaction between Growth factor receptor bound protein 2 and phosphotyrosine-containing p...				J Med Chem 42: 3737-41 (1999) Article DOI: 10.1021/jm9911074 BindingDB Entry DOI: 10.7270/Q2MW2GB6
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50072869 (CHEMBL331463 | Phosphoric acid mono-{4-[(S)-2-acet...) Show SMILES CC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1c(O)ccc2ccccc12 Show InChI InChI=1S/C35H44N5O10P/c1-22(41)38-28(20-23-11-14-25(15-12-23)50-51(47,48)49)33(45)40-35(17-5-2-6-18-35)34(46)39-29(21-31(36)43)32(44)37-19-7-10-27-26-9-4-3-8-24(26)13-16-30(27)42/h3-4,8-9,11-16,28-29,42H,2,5-7,10,17-21H2,1H3,(H2,36,43)(H,37,44)(H,38,41)(H,39,46)(H,40,45)(H2,47,48,49)/t28-,29-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibition of Grb2 SH2 domain binding				J Med Chem 42: 25-35 (1999) Article DOI: 10.1021/jm980388x BindingDB Entry DOI: 10.7270/Q2FT8K6P
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50300042 (4-[(2S)-2-{[(1S)-1-{[(1S)-1,2-dicarbamoylethyl]car...) Show SMILES Cc1ccc(OC(C)(C)C(=O)N[C@@H](Cc2ccc(OP(O)(O)=O)cc2)C(=O)N[C@@](C)(Cc2ccc(OP(O)(O)=O)cc2)C(=O)N[C@@H](CC(N)=O)C(N)=O)c(c1)\N=N\c1ccccc1 |r| Show InChI InChI=1S/C40H47N7O14P2/c1-24-10-19-33(30(20-24)47-46-27-8-6-5-7-9-27)59-39(2,3)37(51)44-32(21-25-11-15-28(16-12-25)60-62(53,54)55)36(50)45-40(4,38(52)43-31(35(42)49)22-34(41)48)23-26-13-17-29(18-14-26)61-63(56,57)58/h5-20,31-32H,21-23H2,1-4H3,(H2,41,48)(H2,42,49)(H,43,52)(H,44,51)(H,45,50)(H2,53,54,55)(H2,56,57,58)/b47-46+/t31-,32-,40-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
CNRS UMR 176 Curated by ChEMBL					Assay Description Inhibition of Grb2 by ELISA				Eur J Med Chem 45: 244-55 (2010) Article DOI: 10.1016/j.ejmech.2009.10.003 BindingDB Entry DOI: 10.7270/Q21C1WZD
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50099450 (CHEMBL19378 | {4-[(S)-2-Acetylamino-2-(1-{(S)-2-ca...) Show SMILES CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCc1ccc2cccc(O)c2c1 Show InChI InChI=1S/C36H46N5O9P/c1-23(42)39-29(20-25-10-12-26(13-11-25)22-51(48,49)50)34(46)41-36(16-3-2-4-17-36)35(47)40-30(21-32(37)44)33(45)38-18-6-7-24-14-15-27-8-5-9-31(43)28(27)19-24/h5,8-15,19,29-30,43H,2-4,6-7,16-18,20-22H2,1H3,(H2,37,44)(H,38,45)(H,39,42)(H,40,47)(H,41,46)(H2,48,49,50)/t29-,30-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
NOVARTIS Pharma AG Curated by ChEMBL					Assay Description Inhibitory concentration required against Src homology (SH2) domain of Growth factor receptor bound protein 2 by ELISA binding assay				Bioorg Med Chem Lett 11: 1201-3 (2001) BindingDB Entry DOI: 10.7270/Q2G1603X
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50085876 (2-{4-[2-Acetylamino-2-(1-{2-carbamoyl-1-[3-(5-meth...) Show SMILES CC(=O)N[C@@H](Cc1ccc(cc1)C(C(O)=O)C(O)=O)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCn1ccc2cc(C)ccc12 Show InChI InChI=1S/C37H46N6O9/c1-22-7-12-29-26(19-22)13-18-43(29)17-6-16-39-32(46)28(21-30(38)45)41-36(52)37(14-4-3-5-15-37)42-33(47)27(40-23(2)44)20-24-8-10-25(11-9-24)31(34(48)49)35(50)51/h7-13,18-19,27-28,31H,3-6,14-17,20-21H2,1-2H3,(H2,38,45)(H,39,46)(H,40,44)(H,41,52)(H,42,47)(H,48,49)(H,50,51)/t27-,28-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibition of Growth factor receptor bound protein 2 binding by ELISA assay method				J Med Chem 43: 911-20 (2000) BindingDB Entry DOI: 10.7270/Q2WD3ZRD
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50143944 (2-[4-((E)-(9S,10S,14S,18S)-18-Carbamoylmethyl-9-ca...) Show SMILES NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C[C@@H](Cc2cccc3ccccc23)CNC1=O)c1ccc(cc1)C(C([O-])=O)C([O-])=O |t:24| Show InChI InChI=1S/C41H46N4O10/c42-33(46)22-32-37(50)43-23-24(20-28-11-7-10-25-9-2-3-12-29(25)28)8-6-13-30(26-14-16-27(17-15-26)35(38(51)52)39(53)54)31(21-34(47)48)36(49)45-41(40(55)44-32)18-4-1-5-19-41/h2-3,6-7,9-17,24,30-32,35H,1,4-5,8,18-23H2,(H2,42,46)(H,43,50)(H,44,55)(H,45,49)(H,47,48)(H,51,52)(H,53,54)/p-2/b13-6+/t24-,30+,31-,32-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12.1	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description In vitro Growth factor receptor bound protein 2-binding affinity of the compound was determined in in surface plasmon resonance (SPR) method				J Med Chem 47: 2166-9 (2004) Article DOI: 10.1021/jm030510e BindingDB Entry DOI: 10.7270/Q2668CNN
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50124298 (2-[9-(4-phosphonooxybenzyl)-21-carbamoyl-24-(4-hyd...) Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](C)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)C2(CCCCC2)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC1=O)C(C)C)C(N)=O Show InChI InChI=1S/C53H77N12O17PS/c1-27(2)20-35-47(73)61-37(22-32-12-16-34(17-13-32)82-83(79,80)81)50(76)65-53(18-8-7-9-19-53)52(78)63-38(23-40(54)67)49(75)64-43(28(3)4)51(77)56-24-41(68)57-29(5)45(71)60-36(21-31-10-14-33(66)15-11-31)48(74)62-39(44(55)70)25-84-26-42(69)58-30(6)46(72)59-35/h10-17,27-30,35-39,43,66H,7-9,18-26H2,1-6H3,(H2,54,67)(H2,55,70)(H,56,77)(H,57,68)(H,58,69)(H,59,72)(H,60,71)(H,61,73)(H,62,74)(H,63,78)(H,64,75)(H,65,76)(H2,79,80,81)/t29-,30-,35-,36-,37-,38-,39-,43-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibition of Growth factor receptor-bound protein 2 (Grb2) SH2 domain binding by ELISA				Bioorg Med Chem Lett 13: 895-9 (2003) BindingDB Entry DOI: 10.7270/Q2SF2VH2
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50497251 (CHEMBL3360189) Show SMILES C[C@](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(=O)OCc1cccc(N)c1)(C(=O)N[C@@H](CC(N)=O)C(N)=O)c1ccc(OP(O)(O)=O)cc1 |r| Show InChI InChI=1S/C30H36N6O14P2/c1-30(28(40)34-23(26(33)38)15-25(32)37,19-7-11-22(12-8-19)50-52(45,46)47)36-27(39)24(14-17-5-9-21(10-6-17)49-51(42,43)44)35-29(41)48-16-18-3-2-4-20(31)13-18/h2-13,23-24H,14-16,31H2,1H3,(H2,32,37)(H2,33,38)(H,34,40)(H,35,41)(H,36,39)(H2,42,43,44)(H2,45,46,47)/t23-,24-,30+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
The University of Texas Curated by ChEMBL					Assay Description Binding affinity to Grb2 SH2 domain (60 to 151) (unknown origin) expressed in Escherichia coli BL21(DE3) after overnight incubation by ELISA				Bioorg Med Chem Lett 24: 3164-7 (2014) Article DOI: 10.1016/j.bmcl.2014.04.114 BindingDB Entry DOI: 10.7270/Q2SN0CZD
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50073908 (CHEMBL70852 | {4-[(S)-2-Acetylamino-2-(1-{(S)-2-ca...) Show SMILES COc1ccc2c(CCCNC(=O)[C@H](CC(N)=O)NC(=O)C3(CCCCC3)NC(=O)[C@H](Cc3ccc(CP(O)(O)=O)cc3)NC(C)=O)c[nH]c2c1 Show InChI InChI=1S/C35H47N6O9P/c1-22(42)39-29(17-23-8-10-24(11-9-23)21-51(47,48)49)33(45)41-35(14-4-3-5-15-35)34(46)40-30(19-31(36)43)32(44)37-16-6-7-25-20-38-28-18-26(50-2)12-13-27(25)28/h8-13,18,20,29-30,38H,3-7,14-17,19,21H2,1-2H3,(H2,36,43)(H,37,44)(H,39,42)(H,40,46)(H,41,45)(H2,47,48,49)/t29-,30-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptor				Bioorg Med Chem Lett 9: 221-6 (1999) BindingDB Entry DOI: 10.7270/Q2N58KJG
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50139762 (CHEMBL349373 | [(16R,20S)-18-((S)-Carbamoylmethyl)...) Show SMILES Cc1ccc2n(C[C@H]3CNC(=O)[C@H](CC(N)=O)NC(=O)C4(CCCCC4)NC(=O)[C@@H](CC(O)=O)[C@H](\C=C\C3)c3ccc(CP(O)(O)=O)cc3)ccc2c1 |t:36| Show InChI InChI=1S/C38H48N5O9P/c1-24-8-13-32-28(18-24)14-17-43(32)22-26-6-5-7-29(27-11-9-25(10-12-27)23-53(50,51)52)30(19-34(45)46)35(47)42-38(15-3-2-4-16-38)37(49)41-31(20-33(39)44)36(48)40-21-26/h5,7-14,17-18,26,29-31H,2-4,6,15-16,19-23H2,1H3,(H2,39,44)(H,40,48)(H,41,49)(H,42,47)(H,45,46)(H2,50,51,52)/b7-5+/t26-,29-,30+,31+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibitory concentration against growth factor receptor bound protein 2				J Med Chem 48: 3945-8 (2005) Article DOI: 10.1021/jm050059m BindingDB Entry DOI: 10.7270/Q2V69J48
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50073916 (CHEMBL72437 | {4-[(S)-2-Acetylamino-2-(1-{(S)-2-ca...) Show SMILES CC(=O)N[C@@H](Cc1ccc(CP(O)(O)=O)cc1)C(=O)NC1(CCCCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCCCn1c(C)cc2ccccc12 Show InChI InChI=1S/C35H47N6O8P/c1-23-19-27-9-4-5-10-30(27)41(23)18-8-17-37-32(44)29(21-31(36)43)39-34(46)35(15-6-3-7-16-35)40-33(45)28(38-24(2)42)20-25-11-13-26(14-12-25)22-50(47,48)49/h4-5,9-14,19,28-29H,3,6-8,15-18,20-22H2,1-2H3,(H2,36,43)(H,37,44)(H,38,42)(H,39,46)(H,40,45)(H2,47,48,49)/t28-,29-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma Inc. Curated by ChEMBL					Assay Description Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptor				Bioorg Med Chem Lett 9: 221-6 (1999) BindingDB Entry DOI: 10.7270/Q2N58KJG
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50124294 (3-[4-(4-phosphonooxybenzyl)-16-carbamoyl-31-carbam...) Show SMILES CC(C)C[C@@H]1NC(=O)[C@H](C)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CC(C)(C)C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc2ccc(OP(O)(O)=O)cc2)NC1=O)C(C)C)C(N)=O Show InChI InChI=1S/C55H81N12O19PS/c1-27(2)19-35-49(77)63-36(21-31-11-15-33(16-12-31)86-87(83,84)85)50(78)61-34(17-18-44(72)73)48(76)65-38(22-41(56)69)52(80)67-45(28(3)4)54(82)58-24-42(70)60-39(23-55(6,7)8)53(81)64-37(20-30-9-13-32(68)14-10-30)51(79)66-40(46(57)74)25-88-26-43(71)59-29(5)47(75)62-35/h9-16,27-29,34-40,45,68H,17-26H2,1-8H3,(H2,56,69)(H2,57,74)(H,58,82)(H,59,71)(H,60,70)(H,61,78)(H,62,75)(H,63,77)(H,64,81)(H,65,76)(H,66,79)(H,67,80)(H,72,73)(H2,83,84,85)/t29-,34-,35-,36-,37-,38-,39-,40-,45-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute Curated by ChEMBL					Assay Description Inhibition of Growth factor receptor-bound protein 2 (Grb2) SH2 domain binding by ELISA				Bioorg Med Chem Lett 13: 895-9 (2003) BindingDB Entry DOI: 10.7270/Q2SF2VH2
					More data for this Ligand-Target Pair
Growth factor receptor-bound protein 2 (Homo sapiens (Human))	BDBM50122797 (CHEMBL406148 | i{4-[18-Carbamoylmethyl-14-(2,3-dih...) Show SMILES NC(=O)C[C@@H]1NC(=O)C2(CCCCC2)NC(=O)C[C@H](\C=C\C[C@@H](CC2=c3ccccc3=CCC2)CNC1=O)c1ccc(CP(O)(O)=O)cc1 |c:25,32,t:20| Show InChI InChI=1S/C37H47N4O7P/c38-33(42)22-32-35(44)39-23-26(20-30-12-7-10-28-9-2-3-13-31(28)30)8-6-11-29(27-16-14-25(15-17-27)24-49(46,47)48)21-34(43)41-37(36(45)40-32)18-4-1-5-19-37/h2-3,6,9-11,13-17,26,29,32H,1,4-5,7-8,12,18-24H2,(H2,38,42)(H,39,44)(H,40,45)(H,41,43)(H2,46,47,48)/b11-6+/t26-,29-,32-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute-Frederick Curated by ChEMBL					Assay Description Inhibition against Growth factor receptor bound protein 2 binding using ELISA technique				J Med Chem 46: 244-54 (2003) Article DOI: 10.1021/jm0203635 BindingDB Entry DOI: 10.7270/Q2RR1XMN
					More data for this Ligand-Target Pair

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