Compile Data Set for Download or QSAR

Found 217 hits of ic50 for UniProtKB: P21675   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346517 (US10202378, Example 121 | o-tolylmethyl 4-(3-hydro...) Show SMILES Cc1[nH]c2c(c1C(=O)OCc1ccccc1C)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C23H24N2O4/c1-14-8-6-7-9-17(14)13-29-22(27)18-15(2)24-20-19(18)16(10-11-23(3,4)28)12-25(5)21(20)26/h6-9,12,24,28H,13H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346549 (US10202378, Example 153 | cyclohexylmethyl 4-(3-hy...) Show SMILES Cc1[nH]c2c(c1C(=O)OCC1CCCCC1)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C22H28N2O4/c1-14-17(21(26)28-13-15-8-6-5-7-9-15)18-16(10-11-22(2,3)27)12-24(4)20(25)19(18)23-14/h12,15,23,27H,5-9,13H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	85.3	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346546 (2,2-dimethylpropyl 4-(3-hydroxy-3-methyl-but-1-yny...) Show SMILES Cc1[nH]c2c(c1C(=O)OCC(C)(C)C)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C20H26N2O4/c1-12-14(18(24)26-11-19(2,3)4)15-13(8-9-20(5,6)25)10-22(7)17(23)16(15)21-12/h10,21,25H,11H2,1-7H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	93.6	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346501 (8-quinolylmethyl 4-(3-cyclopropyl-3-hydroxy-but-1-...) Show SMILES Cc1[nH]c2c(c1C(=O)OCc1cccc3cccnc13)c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	93.9	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346544 (US10202378, Example 148 | cyclopentylmethyl 4-(3-h...) Show SMILES Cc1[nH]c2c(c1C(=O)OCC1CCCC1)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C21H26N2O4/c1-13-16(20(25)27-12-14-7-5-6-8-14)17-15(9-10-21(2,3)26)11-23(4)19(24)18(17)22-13/h11,14,22,26H,5-8,12H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	96.8	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346545 (2-methylbutyl 4-(3-hydroxy-3-methyl-but-1-ynyl)-2,...) Show SMILES CCC(C)COC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(C)O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	101	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346512 (US10202378, Example 116 | [2-(trifluoromethyl)phen...) Show SMILES Cc1[nH]c2c(c1C(=O)OCc1ccccc1C(F)(F)F)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C23H21F3N2O4/c1-13-17(21(30)32-12-15-7-5-6-8-16(15)23(24,25)26)18-14(9-10-22(2,3)31)11-28(4)20(29)19(18)27-13/h5-8,11,27,31H,12H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346492 (3-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-4-(3-cyclopr...) Show SMILES Cc1[nH]c2c(c1-c1nnc(o1)C(C)(C)C)c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346554 (US10202378, Example 158 | isobutyl 4-[(3R)-3-hydro...) Show SMILES CC(C)COC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#C[C@@](C)(O)c1cc(C)on1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346506 ((2-cyanophenyl)methyl 4-(3-hydroxy-3-methyl-but-1-...) Show SMILES Cc1[nH]c2c(c1C(=O)OCc1ccccc1C#N)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C23H21N3O4/c1-14-18(22(28)30-13-17-8-6-5-7-15(17)11-24)19-16(9-10-23(2,3)29)12-26(4)21(27)20(19)25-14/h5-8,12,25,29H,13H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346447 (US10202378, Example 60 | ethyl 4-[2-(3-aminophenyl...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#Cc1cccc(N)c1 Show InChI InChI=1S/C20H19N3O3/c1-4-26-20(25)16-12(2)22-18-17(16)14(11-23(3)19(18)24)9-8-13-6-5-7-15(21)10-13/h5-7,10-11,22H,4,21H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346522 (US10202378, Example 126 | isobutyl 4-(3-cyclopropy...) Show SMILES CC(C)COC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346509 ((2-methoxyphenyl)methyl-4-(3-hydroxy-3-methyl-but-...) Show SMILES COc1ccccc1COC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C23H24N2O5/c1-14-18(22(27)30-13-16-8-6-7-9-17(16)29-5)19-15(10-11-23(2,3)28)12-25(4)21(26)20(19)24-14/h6-9,12,24,28H,13H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346513 (US10202378, Example 117 | p-tolylmethyl 4-(3-hydro...) Show SMILES Cc1[nH]c2c(c1C(=O)OCc1ccc(C)cc1)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C23H24N2O4/c1-14-6-8-16(9-7-14)13-29-22(27)18-15(2)24-20-19(18)17(10-11-23(3,4)28)12-25(5)21(20)26/h6-9,12,24,28H,13H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346556 (US10202378, Example 160 | isobutyl 4-(3-hydroxy-3-...) Show SMILES CC(C)COC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346425 (US10202378, Example 38 | ethyl 4-[(3R)-3-hydroxy-3...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#C[C@@](C)(O)c1cc(C)on1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	136	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346575 (4-(3-cyclopropyl-3-hydroxy-but-1-ynyl)-3-(5-isobut...) Show SMILES CC(C)Cc1nnc(o1)-c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	137	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346422 (US10202378, Example 35 | ethyl 4-(4-cyano-3-hydrox...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)CC#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	139	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346515 ((2-fluorophenyl)methyl 4-(3-hydroxy-3-methyl-but-1...) Show SMILES Cc1[nH]c2c(c1C(=O)OCc1ccccc1F)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C22H21FN2O4/c1-13-17(21(27)29-12-15-7-5-6-8-16(15)23)18-14(9-10-22(2,3)28)11-25(4)20(26)19(18)24-13/h5-8,11,24,28H,12H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	145	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346404 (US10202378, Example 19 | ethyl 4-[3-(3-cyanophenyl...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)c1cccc(c1)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346550 (US10202378, Example 154 | isobutyl 4-(4-cyano-3-hy...) Show SMILES CC(C)COC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)CC#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346499 (Benzyl 4-(3-hydroxy-3-methyl-but-1-ynyl)-2,6-dimet...) Show SMILES Cc1[nH]c2c(c1C(=O)OCc1ccccc1)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C22H22N2O4/c1-14-17(21(26)28-13-15-8-6-5-7-9-15)18-16(10-11-22(2,3)27)12-24(4)20(25)19(18)23-14/h5-9,12,23,27H,13H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	151	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346464 (US10202378, Example 77 | US10202378, Example 92a |...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346538 (1,2-dimethylpropyl 4-[3-hydroxy-3-(5-methylisoxazo...) Show SMILES CC(C)C(C)OC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#C[C@@](C)(O)c1cc(C)on1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346502 (US10202378, Example 106 | [3-(hydroxymethyl)phenyl...) Show SMILES Cc1[nH]c2c(c1C(=O)OCc1cccc(CO)c1)c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	166	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346514 (US10202378, Example 118 | m-tolylmethyl 4-(3-hydro...) Show SMILES Cc1[nH]c2c(c1C(=O)OCc1cccc(C)c1)c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C23H24N2O4/c1-14-7-6-8-16(11-14)13-29-22(27)18-15(2)24-20-19(18)17(9-10-23(3,4)28)12-25(5)21(20)26/h6-8,11-12,24,28H,13H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	167	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346428 (US10202378, Example 41 | ethyl 2,6-dimethyl-7-oxo-...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(O)(c1cccc(c1)-c1cn[nH]c1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	171	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346528 (US10202378, Example 132 | isobutyl 4-(3-hydroxy-3-...) Show SMILES CC(C)COC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C19H24N2O4/c1-11(2)10-25-18(23)14-12(3)20-16-15(14)13(7-8-19(4,5)24)9-21(6)17(16)22/h9,11,20,24H,10H2,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	173	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346476 (US10202378, Example 89 | US10202378, Example 93a |...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(O)(C(F)F)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	176	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346441 (US10202378, Example 54 | isobutyl 4-[(3R)-3-hydrox...) Show SMILES CC(C)COC(=O)c1c[nH]c2c1c(cn(C)c2=O)C#C[C@@](C)(O)c1cc(C)on1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	179	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346408 (US10202378, Example 23 | ethyl 4-(3-hydroxy-3-meth...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)CCc1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	182	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346488 (4-(3-cyclopropyl-3-hydroxy-but-1-ynyl)-2,6-dimethy...) Show SMILES Cc1[nH]c2c(c1-c1nnc(o1)C1CCOC1)c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	182	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346460 (US10202378, Example 73 | US10202378, Example 91a |...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(O)(c1ccccc1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	184	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346592 (US10202378, Example 197 | ethyl 4-[3-(3-carbamoylp...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(O)(c1cccc(c1)C(N)=O)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346496 (US10202378, Example 100 | ethyl 2,6-dimethyl-7-oxo...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(O)(c1cccc(c1)-c1cccnc1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	189	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346484 (3-(5-isopropyl-1,3,4-oxadiazol-2-yl)-2,6-dimethyl-...) Show SMILES CC(C)c1nnc(o1)-c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(O)(c1ccccc1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	192	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346450 (US10202378, Example 63 | ethyl 4-[2-(3-hydroxyphen...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#Cc1cccc(O)c1 Show InChI InChI=1S/C20H18N2O4/c1-4-26-20(25)16-12(2)21-18-17(16)14(11-22(3)19(18)24)9-8-13-6-5-7-15(23)10-13/h5-7,10-11,21,23H,4H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	195	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346577 (4-(3-cyclopropyl-3-hydroxy-but-1-ynyl)-3-(5-ethyl-...) Show SMILES CCc1nnc(o1)-c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	199	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346490 (4-(3-cyclopropyl-3-hydroxy-but-1-ynyl)-3-[5-[(dime...) Show SMILES CN(C)Cc1nnc(o1)-c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	205	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346388 (US10202378, Example 3 | ethyl 4-[3-[4-(dimethylami...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(O)(c1ccc(cc1)N(C)C)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	209	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346456 (US10202378, Example 69 | ethyl 4-[(3R)-3-hydroxy-3...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#C[C@@](C)(O)c1cc(C)no1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346486 (3-[5-[(dimethylamino)methyl]-1,3,4-oxadiazol-2-yl]...) Show SMILES CN(C)Cc1nnc(o1)-c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(O)(c1ccccc1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	211	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346401 (US10202378, Example 16 | ethyl 4-(3-hydroxy-3-meth...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)Cc1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	212	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346562 (2-cyanoethyl 2,6-dimethyl-7-oxo-4-(4,4,4-trifluoro...) Show SMILES Cc1[nH]c2c(c1C(=O)OCCC#N)c(cn(C)c2=O)C#CC(O)(c1ccccc1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	214	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346492 (3-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-4-(3-cyclopr...) Show SMILES Cc1[nH]c2c(c1-c1nnc(o1)C(C)(C)C)c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	216	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346420 (US10202378, Example 33 | ethyl 4-[3-(3-fluoropheny...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(O)c1cccc(F)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	218	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346547 (1,1-dimethylpropyl 4-(3-hydroxy-3-methyl-but-1-yny...) Show SMILES CCC(C)(C)OC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(C)(C)O Show InChI InChI=1S/C20H26N2O4/c1-8-20(5,6)26-18(24)14-12(2)21-16-15(14)13(9-10-19(3,4)25)11-22(7)17(16)23/h11,21,25H,8H2,1-7H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	221	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346505 (US10202378, Example 109 | thiazol-2-ylmethyl 4-(3-...) Show SMILES Cc1[nH]c2c(c1C(=O)OCc1nccs1)c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	222	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346530 ((2-cyano-1,1-dimethyl-ethyl)-4-(3-cyclopropyl-3-hy...) Show SMILES Cc1[nH]c2c(c1C(=O)OC(C)(C)CC#N)c(cn(C)c2=O)C#CC(C)(O)C1CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	222	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair
Transcription initiation factor TFIID subunit 1 [1381-1497] (Homo sapiens (human))	BDBM346431 (US10202378, Example 44 | ethyl 2,6-dimethyl-7-oxo-...) Show SMILES CCOC(=O)c1c(C)[nH]c2c1c(cn(C)c2=O)C#CC(O)(c1cccc(c1)-c1cc[nH]n1)C(F)(F)F Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	226	n/a	n/a	n/a	n/a	n/a	n/a
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC. US Patent					Assay Description His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...				US Patent US10202378 (2019) BindingDB Entry DOI: 10.7270/Q22B9149
					More data for this Ligand-Target Pair

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