Compile Data Set for Download or QSAR

Found 287 hits of ec50 for UniProtKB: P40763   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Signal transducer and activator of transcription 3 [702-738,740-752] (Homo sapiens (Human))	BDBM43688 ((E)-2-(1H-Benzoimidazol-2-yl)-3-(5-morpholin-4-yl-...) Show SMILES N#C\C(=C/c1ccc(o1)N1CCOCC1)c1nc2ccccc2[nH]1 Show InChI InChI=1S/C18H16N4O2/c19-12-13(18-20-15-3-1-2-4-16(15)21-18)11-14-5-6-17(24-14)22-7-9-23-10-8-22/h1-6,11H,7-10H2,(H,20,21)/b13-11+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	>25.5	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2BV7F28
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50252660 (Benzyl 1-(4-Cyano-2,3,5,6-tetrafluorophenyl)-6,7,8...) Show SMILES Fc1cc2c(c(F)c1F)n(cc(C(=O)OCc1ccccc1)c2=O)-c1c(F)c(F)c(C#N)c(F)c1F |(-10.27,-12.39,;-8.94,-13.16,;-7.61,-12.39,;-6.28,-13.15,;-6.27,-14.71,;-7.61,-15.48,;-7.61,-17.02,;-8.94,-14.7,;-10.28,-15.47,;-4.93,-15.48,;-3.58,-14.7,;-3.59,-13.14,;-2.26,-12.37,;-2.26,-10.83,;-.92,-13.13,;.41,-12.36,;1.75,-13.13,;1.74,-14.66,;3.08,-15.43,;4.41,-14.65,;4.4,-13.11,;3.06,-12.35,;-4.94,-12.37,;-4.95,-10.83,;-4.92,-17.01,;-3.59,-17.77,;-2.26,-16.99,;-3.58,-19.31,;-2.24,-20.07,;-4.91,-20.09,;-4.91,-21.63,;-4.92,-23.16,;-6.25,-19.32,;-7.58,-20.09,;-6.25,-17.78,;-7.6,-18.54,)| Show InChI InChI=1S/C24H9F7N2O3/c25-14-6-11-21(20(31)17(14)28)33(22-18(29)15(26)12(7-32)16(27)19(22)30)8-13(23(11)34)24(35)36-9-10-4-2-1-3-5-10/h1-6,8H,9H2	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of STAT3 Y705 phosphorylation in human U266 cells by western blot analysis				J Med Chem 51: 4115-21 (2008) Article DOI: 10.1021/jm701271y BindingDB Entry DOI: 10.7270/Q2B27V3R
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50252612 (CHEMBL524195 | Ethyl 1-(4-Cyano-2,3,5,6-tetrafluor...) Show SMILES CCOC(=O)c1cn(-c2c(F)c(F)c(C#N)c(F)c2F)c2c(F)c(F)c(F)cc2c1=O |(32.1,3.51,;30.76,4.28,;29.43,3.5,;28.1,4.27,;28.09,5.81,;26.77,3.49,;26.77,1.94,;25.43,1.16,;25.44,-.37,;26.77,-1.13,;28.1,-.36,;26.78,-2.67,;28.11,-3.43,;25.44,-3.45,;25.45,-4.99,;25.44,-6.52,;24.1,-2.68,;22.77,-3.46,;24.1,-1.15,;22.76,-1.91,;24.09,1.93,;22.75,1.16,;22.74,-.38,;21.41,1.93,;20.08,1.16,;21.41,3.48,;20.08,4.25,;22.74,4.25,;24.08,3.48,;25.41,4.27,;25.41,5.81,)| Show InChI InChI=1S/C19H7F7N2O3/c1-2-31-19(30)8-5-28(16-6(18(8)29)3-9(20)12(23)15(16)26)17-13(24)10(21)7(4-27)11(22)14(17)25/h3,5H,2H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of STAT3 Y705 phosphorylation in human U266 cells by western blot analysis				J Med Chem 51: 4115-21 (2008) Article DOI: 10.1021/jm701271y BindingDB Entry DOI: 10.7270/Q2B27V3R
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50252661 (1-(4-Cyano-2,3,5,6-tetrafluorophenyl)-6,7,8-triflu...) Show SMILES Fc1ccc(CNC(=O)c2cn(-c3c(F)c(F)c(C#N)c(F)c3F)c3c(F)c(F)c(F)cc3c2=O)cc1 |(24.77,-14.19,;23.43,-13.43,;22.1,-14.2,;20.77,-13.43,;20.77,-11.9,;19.44,-11.13,;18.1,-11.91,;16.77,-11.14,;16.76,-9.6,;15.44,-11.91,;15.44,-13.47,;14.1,-14.25,;14.11,-15.78,;15.44,-16.54,;16.77,-15.76,;15.45,-18.08,;16.79,-18.84,;14.11,-18.86,;14.12,-20.4,;14.11,-21.93,;12.77,-18.09,;11.44,-18.86,;12.77,-16.55,;11.43,-17.31,;12.76,-13.48,;11.42,-14.25,;11.41,-15.79,;10.08,-13.48,;8.75,-14.24,;10.09,-11.93,;8.75,-11.16,;11.41,-11.16,;12.75,-11.92,;14.09,-11.14,;14.08,-9.6,;22.09,-11.12,;23.42,-11.88,)| Show InChI InChI=1S/C24H9F8N3O2/c25-10-3-1-9(2-4-10)7-34-24(37)13-8-35(21-11(23(13)36)5-14(26)17(29)20(21)32)22-18(30)15(27)12(6-33)16(28)19(22)31/h1-5,8H,7H2,(H,34,37)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of STAT3 Y705 phosphorylation in human U266 cells by western blot analysis				J Med Chem 51: 4115-21 (2008) Article DOI: 10.1021/jm701271y BindingDB Entry DOI: 10.7270/Q2B27V3R
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 [702-738,740-752] (Homo sapiens (Human))	BDBM43686 ((E)-2-cyano-3-(2,5-dimethyl-1-phenyl-3-pyrrolyl)-2...) Show SMILES CCOC(=O)C(=C\c1cc(C)n(c1C)-c1ccccc1)\C#N Show InChI InChI=1S/C18H18N2O2/c1-4-22-18(21)16(12-19)11-15-10-13(2)20(14(15)3)17-8-6-5-7-9-17/h5-11H,4H2,1-3H3/b16-11+	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	PCBioAssay	n/a	n/a	n/a	n/a	>688	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2BV7F28
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50366601 (CHEMBL4171066) Show SMILES CC(=O)c1cc2c(o1)-c1ccccc1C(=O)C2=O Show InChI InChI=1S/C14H8O4/c1-7(15)11-6-10-13(17)12(16)8-4-2-3-5-9(8)14(10)18-11/h2-6H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
Westphalian Wilhelms University Curated by ChEMBL					Assay Description Inhibition of STAT3 phosphorylation at Y705 in human MDA-MB-231 cells assessed as reduction in ratio of phosphorylated STAT3 to total STAT3 level aft...				J Nat Prod 81: 1636-1644 (2018) Article DOI: 10.1021/acs.jnatprod.8b00247 BindingDB Entry DOI: 10.7270/Q2KW5JK0
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 [702-738,740-752] (Homo sapiens (Human))	BDBM30718 (7-(diethylamino)-2-keto-N-(2-pyridyl)chromene-3-ca...) Show SMILES CCN(CC)c1ccc2cc(C(=O)Nc3ccccn3)c(=O)oc2c1 Show InChI InChI=1S/C19H19N3O3/c1-3-22(4-2)14-9-8-13-11-15(19(24)25-16(13)12-14)18(23)21-17-7-5-6-10-20-17/h5-12H,3-4H2,1-2H3,(H,20,21,23)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	804	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2BV7F28
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50366601 (CHEMBL4171066) Show SMILES CC(=O)c1cc2c(o1)-c1ccccc1C(=O)C2=O Show InChI InChI=1S/C14H8O4/c1-7(15)11-6-10-13(17)12(16)8-4-2-3-5-9(8)14(10)18-11/h2-6H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	870	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1016/j.ejmech.2021.113632 BindingDB Entry DOI: 10.7270/Q2QJ7N79
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50366601 (CHEMBL4171066) Show SMILES CC(=O)c1cc2c(o1)-c1ccccc1C(=O)C2=O Show InChI InChI=1S/C14H8O4/c1-7(15)11-6-10-13(17)12(16)8-4-2-3-5-9(8)14(10)18-11/h2-6H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	870	n/a	n/a	n/a	n/a
Westphalian Wilhelms University Curated by ChEMBL					Assay Description Inhibition of STAT3 phosphorylation at Y705 in human MDA-MB-231 cells after 4 hrs by HTRF assay				J Nat Prod 81: 1636-1644 (2018) Article DOI: 10.1021/acs.jnatprod.8b00247 BindingDB Entry DOI: 10.7270/Q2KW5JK0
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450176 (CHEMBL4168778) Show SMILES [H][C@]12[#6]-[#6]-[#6](=[#6])-[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#6]-[#8]-[#6]-3=O)-[#8]-[#6](-[#6])=O)[C@]1([#6])[#6]-[#6]-[#6](=O)[C@@]2([#6])[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6] |r| Show InChI InChI=1S/C28H44O6Si/c1-18-10-13-23-27(6,21(18)12-11-20-22(34-19(2)29)16-32-25(20)31)15-14-24(30)28(23,7)17-33-35(8,9)26(3,4)5/h11,21-23H,1,10,12-17H2,2-9H3/b20-11+/t21-,22-,23+,27+,28+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	990	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IL-6 stimulated STAT3 activation in human AD293 cells incubated with IL-6 for 16 hrs followed by compound addition measured after 6 hrs...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450156 (CHEMBL1933810) Show SMILES [H][C@]12[#6]-[#6]-[#6](=[#6])-[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#6]-[#8]-[#6]-3=O)-[#8]-[#6](-[#6])=O)[C@]1([#6])[#6]-[#6]-[#6@@H](-[#8])[C@@]2([#6])[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6] |r| Show InChI InChI=1S/C28H46O6Si/c1-18-10-13-23-27(6,21(18)12-11-20-22(34-19(2)29)16-32-25(20)31)15-14-24(30)28(23,7)17-33-35(8,9)26(3,4)5/h11,21-24,30H,1,10,12-17H2,2-9H3/b20-11+/t21-,22-,23+,24-,27+,28+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50366597 (2-Acetylfuranonaphthoquinone | BBI-608 | Napabucas...) Show SMILES CC(=O)c1cc2c(o1)C(=O)c1ccccc1C2=O Show InChI InChI=1S/C14H8O4/c1-7(15)11-6-10-12(16)8-4-2-3-5-9(8)13(17)14(10)18-11/h2-6H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a
Westphalian Wilhelms University Curated by ChEMBL					Assay Description Inhibition of STAT3 phosphorylation at Y705 in human MDA-MB-231 cells assessed as reduction in ratio of phosphorylated STAT3 to total STAT3 level aft...				J Nat Prod 81: 1636-1644 (2018) Article DOI: 10.1021/acs.jnatprod.8b00247 BindingDB Entry DOI: 10.7270/Q2KW5JK0
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450176 (CHEMBL4168778) Show SMILES [H][C@]12[#6]-[#6]-[#6](=[#6])-[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#6]-[#8]-[#6]-3=O)-[#8]-[#6](-[#6])=O)[C@]1([#6])[#6]-[#6]-[#6](=O)[C@@]2([#6])[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6] |r| Show InChI InChI=1S/C28H44O6Si/c1-18-10-13-23-27(6,21(18)12-11-20-22(34-19(2)29)16-32-25(20)31)15-14-24(30)28(23,7)17-33-35(8,9)26(3,4)5/h11,21-23H,1,10,12-17H2,2-9H3/b20-11+/t21-,22-,23+,27+,28+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.97E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50366597 (2-Acetylfuranonaphthoquinone | BBI-608 | Napabucas...) Show SMILES CC(=O)c1cc2c(o1)C(=O)c1ccccc1C2=O Show InChI InChI=1S/C14H8O4/c1-7(15)11-6-10-12(16)8-4-2-3-5-9(8)13(17)14(10)18-11/h2-6H,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a
Westphalian Wilhelms University Curated by ChEMBL					Assay Description Inhibition of STAT3 phosphorylation at Y705 in human MDA-MB-231 cells after 4 hrs by HTRF assay				J Nat Prod 81: 1636-1644 (2018) Article DOI: 10.1021/acs.jnatprod.8b00247 BindingDB Entry DOI: 10.7270/Q2KW5JK0
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450156 (CHEMBL1933810) Show SMILES [H][C@]12[#6]-[#6]-[#6](=[#6])-[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#6]-[#8]-[#6]-3=O)-[#8]-[#6](-[#6])=O)[C@]1([#6])[#6]-[#6]-[#6@@H](-[#8])[C@@]2([#6])[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6] |r| Show InChI InChI=1S/C28H46O6Si/c1-18-10-13-23-27(6,21(18)12-11-20-22(34-19(2)29)16-32-25(20)31)15-14-24(30)28(23,7)17-33-35(8,9)26(3,4)5/h11,21-24,30H,1,10,12-17H2,2-9H3/b20-11+/t21-,22-,23+,24-,27+,28+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.21E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IL-6 stimulated STAT3 activation in human AD293 cells incubated with IL-6 for 16 hrs followed by compound addition measured after 6 hrs...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450155 (CHEMBL4171438) Show SMILES [H][C@]12[#6]-[#6][C@@]3([#6]-[#8]3)[#6@@H](-[#6]\[#6]=[#6]-3/[#6@H](-[#6]-[#8]-[#6]-3=O)-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])[C@]1([#6])[#6]-[#6]-[#6](=O)[C@@]2([#6])[#6]-[#8]-[#6](-[#6])=O |r| Show InChI InChI=1S/C28H44O7Si/c1-18(29)33-16-27(6)21-11-14-28(17-34-28)22(26(21,5)13-12-23(27)30)10-9-19-20(15-32-24(19)31)35-36(7,8)25(2,3)4/h9,20-22H,10-17H2,1-8H3/b19-9+/t20-,21-,22-,26+,27-,28+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.23E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450150 (CHEMBL4163208) Show SMILES [H][C@]12[#6]-[#6][C@]3([#6]-[#8]3)[#6@@H](-[#6]\[#6]=[#6]-3/[#6@H](-[#6]-[#8]-[#6]-3=O)-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])[C@]1([#6])[#6]-[#6]-[#6](=O)[C@@]2([#6])[#6]-[#8]-[#6](-[#6])=O |r| Show InChI InChI=1S/C28H44O7Si/c1-18(29)33-16-27(6)21-11-14-28(17-34-28)22(26(21,5)13-12-23(27)30)10-9-19-20(15-32-24(19)31)35-36(7,8)25(2,3)4/h9,20-22H,10-17H2,1-8H3/b19-9+/t20-,21-,22-,26+,27-,28-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.55E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450155 (CHEMBL4171438) Show SMILES [H][C@]12[#6]-[#6][C@@]3([#6]-[#8]3)[#6@@H](-[#6]\[#6]=[#6]-3/[#6@H](-[#6]-[#8]-[#6]-3=O)-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])[C@]1([#6])[#6]-[#6]-[#6](=O)[C@@]2([#6])[#6]-[#8]-[#6](-[#6])=O |r| Show InChI InChI=1S/C28H44O7Si/c1-18(29)33-16-27(6)21-11-14-28(17-34-28)22(26(21,5)13-12-23(27)30)10-9-19-20(15-32-24(19)31)35-36(7,8)25(2,3)4/h9,20-22H,10-17H2,1-8H3/b19-9+/t20-,21-,22-,26+,27-,28+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.56E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IL-6 stimulated STAT3 activation in human AD293 cells incubated with IL-6 for 16 hrs followed by compound addition measured after 6 hrs...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450178 (CHEMBL360826) Show SMILES [H][C@]12CC[C@@]3(CO3)[C@@H](C\C=C3/[C@@H](COC3=O)OC(C)=O)[C@]1(C)CC[C@@H](O)[C@@]2(C)CO Show InChI InChI=1S/C22H32O7/c1-13(24)29-15-10-27-19(26)14(15)4-5-17-20(2)8-7-18(25)21(3,11-23)16(20)6-9-22(17)12-28-22/h4,15-18,23,25H,5-12H2,1-3H3/b14-4+/t15-,16+,17+,18-,20-,21+,22-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450150 (CHEMBL4163208) Show SMILES [H][C@]12[#6]-[#6][C@]3([#6]-[#8]3)[#6@@H](-[#6]\[#6]=[#6]-3/[#6@H](-[#6]-[#8]-[#6]-3=O)-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])[C@]1([#6])[#6]-[#6]-[#6](=O)[C@@]2([#6])[#6]-[#8]-[#6](-[#6])=O |r| Show InChI InChI=1S/C28H44O7Si/c1-18(29)33-16-27(6)21-11-14-28(17-34-28)22(26(21,5)13-12-23(27)30)10-9-19-20(15-32-24(19)31)35-36(7,8)25(2,3)4/h9,20-22H,10-17H2,1-8H3/b19-9+/t20-,21-,22-,26+,27-,28-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.65E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IL-6 stimulated STAT3 activation in human AD293 cells incubated with IL-6 for 16 hrs followed by compound addition measured after 6 hrs...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50396177 (NIFUROXAZIDE) Show SMILES Oc1ccc(cc1)C(=O)N\N=C\c1ccc(o1)[N+]([O-])=O Show InChI InChI=1S/C12H9N3O5/c16-9-3-1-8(2-4-9)12(17)14-13-7-10-5-6-11(20-10)15(18)19/h1-7,16H,(H,14,17)/b13-7+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of STAT3 expressed in human U3A cells after 1 hr by luciferase reporter gene assay				J Med Chem 55: 6645-68 (2012) Article DOI: 10.1021/jm300207s BindingDB Entry DOI: 10.7270/Q2CJ8FKK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450178 (CHEMBL360826) Show SMILES [H][C@]12CC[C@@]3(CO3)[C@@H](C\C=C3/[C@@H](COC3=O)OC(C)=O)[C@]1(C)CC[C@@H](O)[C@@]2(C)CO Show InChI InChI=1S/C22H32O7/c1-13(24)29-15-10-27-19(26)14(15)4-5-17-20(2)8-7-18(25)21(3,11-23)16(20)6-9-22(17)12-28-22/h4,15-18,23,25H,5-12H2,1-3H3/b14-4+/t15-,16+,17+,18-,20-,21+,22-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.04E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IL-6 stimulated STAT3 activation in human AD293 cells incubated with IL-6 for 16 hrs followed by compound addition measured after 6 hrs...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450146 (CHEMBL4167607) Show SMILES [H][C@]12[#6]-[#6][C@]3([#6]-[#8]3)[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#6]-[#8]-[#6]-3=O)-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])[C@]1([#6])[#6]-[#6]-[#6@@H](-[#8])[C@@]2([#6])[#6]-[#8] |r| Show InChI InChI=1S/C26H44O6Si/c1-23(2,3)33(6,7)32-18-14-30-22(29)17(18)8-9-20-24(4)12-11-21(28)25(5,15-27)19(24)10-13-26(20)16-31-26/h8,18-21,27-28H,9-16H2,1-7H3/b17-8+/t18-,19+,20+,21-,24-,25+,26+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.05E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IL-6 stimulated STAT3 activation in human AD293 cells incubated with IL-6 for 16 hrs followed by compound addition measured after 6 hrs...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450148 (CHEMBL4162115) Show SMILES [H][C@]12CC[C@]3(CO3)[C@@H](C\C=C3/[C@@H](COC3=O)OC(C)=O)[C@]1(C)CC[C@@H](O)[C@@]2(C)CO |r| Show InChI InChI=1S/C22H32O7/c1-13(24)29-15-10-27-19(26)14(15)4-5-17-20(2)8-7-18(25)21(3,11-23)16(20)6-9-22(17)12-28-22/h4,15-18,23,25H,5-12H2,1-3H3/b14-4+/t15-,16+,17+,18-,20-,21+,22+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.11E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IL-6 stimulated STAT3 activation in human AD293 cells incubated with IL-6 for 16 hrs followed by compound addition measured after 6 hrs...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450157 (CHEMBL4163992) Show SMILES [H][C@]12[#6]-[#6]-[#6](=[#6])-[#6@@H](-[#6]\[#6]=[#6]-3/[#6@H](-[#6]-[#8]-[#6]-3=O)-[#8]-[#6](-[#6])=O)[C@]1([#6])[#6]-[#6]-[#6@@H](-[#8])[C@@]2([#6])[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6] |r| Show InChI InChI=1S/C28H46O6Si/c1-18-10-13-23-27(6,21(18)12-11-20-22(34-19(2)29)16-32-25(20)31)15-14-24(30)28(23,7)17-33-35(8,9)26(3,4)5/h11,21-24,30H,1,10,12-17H2,2-9H3/b20-11+/t21-,22+,23+,24-,27+,28+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.22E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IL-6 stimulated STAT3 activation in human AD293 cells incubated with IL-6 for 16 hrs followed by compound addition measured after 6 hrs...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450154 (CHEMBL4172126) Show SMILES [H][C@]12[#6]-[#6]-[#6](=[#6])-[#6@@H](-[#6]\[#6]=[#6]-3/[#6@H](-[#8])-[#6]-[#8]-[#6]-3=O)[C@]1([#6])[#6]-[#6]-[#6](=O)[C@@]2([#6])[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6] |r| Show InChI InChI=1S/C26H42O5Si/c1-17-9-12-21-25(5,19(17)11-10-18-20(27)15-30-23(18)29)14-13-22(28)26(21,6)16-31-32(7,8)24(2,3)4/h10,19-21,27H,1,9,11-16H2,2-8H3/b18-10+/t19-,20-,21+,25+,26+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.45E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450146 (CHEMBL4167607) Show SMILES [H][C@]12[#6]-[#6][C@]3([#6]-[#8]3)[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#6]-[#8]-[#6]-3=O)-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])[C@]1([#6])[#6]-[#6]-[#6@@H](-[#8])[C@@]2([#6])[#6]-[#8] |r| Show InChI InChI=1S/C26H44O6Si/c1-23(2,3)33(6,7)32-18-14-30-22(29)17(18)8-9-20-24(4)12-11-21(28)25(5,15-27)19(24)10-13-26(20)16-31-26/h8,18-21,27-28H,9-16H2,1-7H3/b17-8+/t18-,19+,20+,21-,24-,25+,26+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.45E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450143 (CHEMBL4173895) Show SMILES [H][C@]12[#6]-[#6][C@]3([#6]-[#8]3)[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#6]-[#8]-[#6]-3=O)-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])[C@]1([#6])[#6]-[#6]-[#6](=O)[C@@]2([#6])[#6]-[#8] |r| Show InChI InChI=1S/C26H42O6Si/c1-23(2,3)33(6,7)32-18-14-30-22(29)17(18)8-9-20-24(4)12-11-21(28)25(5,15-27)19(24)10-13-26(20)16-31-26/h8,18-20,27H,9-16H2,1-7H3/b17-8+/t18-,19+,20+,24-,25+,26+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.95E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IL-6 stimulated STAT3 activation in human AD293 cells incubated with IL-6 for 16 hrs followed by compound addition measured after 6 hrs...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450144 (CHEMBL4171230) Show SMILES [H][C@]12[#6]-[#6][C@@]3([#6]-[#8]3)[#6@@H](-[#6]\[#6]=[#6]-3/[#6@H](-[#8])-[#6]-[#8]-[#6]-3=O)[C@]1([#6])[#6]-[#6]-[#6@@H](-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])[C@@]2([#6])[#6]-[#8] |r| Show InChI InChI=1S/C26H44O6Si/c1-23(2,3)33(6,7)32-21-11-12-24(4)19(25(21,5)15-27)10-13-26(16-31-26)20(24)9-8-17-18(28)14-30-22(17)29/h8,18-21,27-28H,9-16H2,1-7H3/b17-8+/t18-,19+,20+,21-,24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.16E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IL-6 stimulated STAT3 activation in human AD293 cells incubated with IL-6 for 16 hrs followed by compound addition measured after 6 hrs...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450156 (CHEMBL1933810) Show SMILES [H][C@]12[#6]-[#6]-[#6](=[#6])-[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#6]-[#8]-[#6]-3=O)-[#8]-[#6](-[#6])=O)[C@]1([#6])[#6]-[#6]-[#6@@H](-[#8])[C@@]2([#6])[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6] |r| Show InChI InChI=1S/C28H46O6Si/c1-18-10-13-23-27(6,21(18)12-11-20-22(34-19(2)29)16-32-25(20)31)15-14-24(30)28(23,7)17-33-35(8,9)26(3,4)5/h11,21-24,30H,1,10,12-17H2,2-9H3/b20-11+/t21-,22-,23+,24-,27+,28+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.33E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human HeLa cells incubated with IFNgamma for 16 hrs followed by compound addition measured afte...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450140 (CHEMBL4162746) Show SMILES [H][C@]12[#6]-[#6]-[#6](=[#6])-[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#8])-[#6]-[#8]-[#6]-3=O)[C@]1([#6])[#6]-[#6]-[#6](=O)[C@@]2([#6])[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6] |r| Show InChI InChI=1S/C26H42O5Si/c1-17-9-12-21-25(5,19(17)11-10-18-20(27)15-30-23(18)29)14-13-22(28)26(21,6)16-31-32(7,8)24(2,3)4/h10,19-21,27H,1,9,11-16H2,2-8H3/b18-10+/t19-,20+,21+,25+,26+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.34E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IL-6 stimulated STAT3 activation in human AD293 cells incubated with IL-6 for 16 hrs followed by compound addition measured after 6 hrs...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450141 (CHEMBL4165560) Show SMILES [H][C@]12[#6]-[#6][C@]3([#6]-[#8]3)[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#6]-[#8]-[#6]-3=O)-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])[C@]1([#6])[#6]-[#6]-[#6](=O)[C@@]2([#6])[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6] |r| Show InChI InChI=1S/C32H56O6Si2/c1-28(2,3)39(9,10)37-20-31(8)24-15-18-32(21-36-32)25(30(24,7)17-16-26(31)33)14-13-22-23(19-35-27(22)34)38-40(11,12)29(4,5)6/h13,23-25H,14-21H2,1-12H3/b22-13+/t23-,24+,25+,30-,31+,32+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450176 (CHEMBL4168778) Show SMILES [H][C@]12[#6]-[#6]-[#6](=[#6])-[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#6]-[#8]-[#6]-3=O)-[#8]-[#6](-[#6])=O)[C@]1([#6])[#6]-[#6]-[#6](=O)[C@@]2([#6])[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6] |r| Show InChI InChI=1S/C28H44O6Si/c1-18-10-13-23-27(6,21(18)12-11-20-22(34-19(2)29)16-32-25(20)31)15-14-24(30)28(23,7)17-33-35(8,9)26(3,4)5/h11,21-23H,1,10,12-17H2,2-9H3/b20-11+/t21-,22-,23+,27+,28+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.43E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human HeLa cells incubated with IFNgamma for 16 hrs followed by compound addition measured afte...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450176 (CHEMBL4168778) Show SMILES [H][C@]12[#6]-[#6]-[#6](=[#6])-[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#6]-[#8]-[#6]-3=O)-[#8]-[#6](-[#6])=O)[C@]1([#6])[#6]-[#6]-[#6](=O)[C@@]2([#6])[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6] |r| Show InChI InChI=1S/C28H44O6Si/c1-18-10-13-23-27(6,21(18)12-11-20-22(34-19(2)29)16-32-25(20)31)15-14-24(30)28(23,7)17-33-35(8,9)26(3,4)5/h11,21-23H,1,10,12-17H2,2-9H3/b20-11+/t21-,22-,23+,27+,28+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.57E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of NF-kappaB stimulated STAT3 activation in human HeLa cells incubated with NF-kappaB for 16 hrs followed by compound addition measured af...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50252610 (CHEMBL494257 | Ethyl 5,6,7,8-tetrafluoro-4-oxo-1-(...) Show SMILES CCOC(=O)c1cn(-c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2c1=O |(2.69,3,;1.36,3.77,;.03,3,;-1.31,3.76,;-1.31,5.3,;-2.64,2.99,;-2.63,1.43,;-3.98,.65,;-3.97,-.88,;-2.64,-1.64,;-1.31,-.86,;-2.63,-3.17,;-1.29,-3.93,;-3.96,-3.96,;-3.96,-5.49,;-5.3,-3.19,;-6.63,-3.96,;-5.3,-1.65,;-6.65,-2.41,;-5.32,1.42,;-6.65,.66,;-6.66,-.88,;-7.99,1.43,;-9.32,.66,;-7.99,2.97,;-9.32,3.74,;-6.66,3.74,;-6.66,5.28,;-5.32,2.98,;-3.99,3.76,;-4,5.3,)| Show InChI InChI=1S/C18H6F9NO3/c1-2-31-18(30)4-3-28(16-13(26)10(23)8(21)11(24)14(16)27)15-5(17(4)29)6(19)7(20)9(22)12(15)25/h3H,2H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of STAT3 Y705 phosphorylation in human U266 cells by western blot analysis				J Med Chem 51: 4115-21 (2008) Article DOI: 10.1021/jm701271y BindingDB Entry DOI: 10.7270/Q2B27V3R
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450140 (CHEMBL4162746) Show SMILES [H][C@]12[#6]-[#6]-[#6](=[#6])-[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#8])-[#6]-[#8]-[#6]-3=O)[C@]1([#6])[#6]-[#6]-[#6](=O)[C@@]2([#6])[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6] |r| Show InChI InChI=1S/C26H42O5Si/c1-17-9-12-21-25(5,19(17)11-10-18-20(27)15-30-23(18)29)14-13-22(28)26(21,6)16-31-32(7,8)24(2,3)4/h10,19-21,27H,1,9,11-16H2,2-8H3/b18-10+/t19-,20+,21+,25+,26+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.72E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450177 (CHEMBL4164249) Show SMILES [H][C@]12[#6]-[#6]-[#6](=[#6])-[#6@@H](-[#6]\[#6]=[#6]-3/[#6@H](-[#6]-[#8]-[#6]-3=O)-[#8]-[#6](-[#6])=O)[C@]1([#6])[#6]-[#6]-[#6](=O)[C@@]2([#6])[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6] |r| Show InChI InChI=1S/C28H44O6Si/c1-18-10-13-23-27(6,21(18)12-11-20-22(34-19(2)29)16-32-25(20)31)15-14-24(30)28(23,7)17-33-35(8,9)26(3,4)5/h11,21-23H,1,10,12-17H2,2-9H3/b20-11+/t21-,22+,23+,27+,28+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.75E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450177 (CHEMBL4164249) Show SMILES [H][C@]12[#6]-[#6]-[#6](=[#6])-[#6@@H](-[#6]\[#6]=[#6]-3/[#6@H](-[#6]-[#8]-[#6]-3=O)-[#8]-[#6](-[#6])=O)[C@]1([#6])[#6]-[#6]-[#6](=O)[C@@]2([#6])[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6] |r| Show InChI InChI=1S/C28H44O6Si/c1-18-10-13-23-27(6,21(18)12-11-20-22(34-19(2)29)16-32-25(20)31)15-14-24(30)28(23,7)17-33-35(8,9)26(3,4)5/h11,21-23H,1,10,12-17H2,2-9H3/b20-11+/t21-,22+,23+,27+,28+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.78E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IL-6 stimulated STAT3 activation in human AD293 cells incubated with IL-6 for 16 hrs followed by compound addition measured after 6 hrs...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450158 (CHEMBL1933811) Show SMILES [H][C@]12[#6]-[#6]-[#6](=[#6])-[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#6]-[#8]-[#6]-3=O)-[#8]-[#6](-[#6])=O)[C@]1([#6])[#6]-[#6]-[#6@@H](-[#8]-[#6](-[#6])=O)[C@@]2([#6])[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6] |r| Show InChI InChI=1S/C30H48O7Si/c1-19-11-14-25-29(7,23(19)13-12-22-24(36-20(2)31)17-34-27(22)33)16-15-26(37-21(3)32)30(25,8)18-35-38(9,10)28(4,5)6/h12,23-26H,1,11,13-18H2,2-10H3/b22-12+/t23-,24-,25+,26-,29+,30+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.05E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450148 (CHEMBL4162115) Show SMILES [H][C@]12CC[C@]3(CO3)[C@@H](C\C=C3/[C@@H](COC3=O)OC(C)=O)[C@]1(C)CC[C@@H](O)[C@@]2(C)CO |r| Show InChI InChI=1S/C22H32O7/c1-13(24)29-15-10-27-19(26)14(15)4-5-17-20(2)8-7-18(25)21(3,11-23)16(20)6-9-22(17)12-28-22/h4,15-18,23,25H,5-12H2,1-3H3/b14-4+/t15-,16+,17+,18-,20-,21+,22+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.11E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450147 (CHEMBL4159896) Show SMILES [H][C@]12[#6]-[#6][C@]3([#6]-[#8]3)[#6@@H](-[#6]\[#6]=[#6]-3/[#6@H](-[#8])-[#6]-[#8]-[#6]-3=O)[C@]1([#6])[#6]-[#6]-[#6@@H](-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])[C@@]2([#6])[#6]-[#8] |r| Show InChI InChI=1S/C26H44O6Si/c1-23(2,3)33(6,7)32-21-11-12-24(4)19(25(21,5)15-27)10-13-26(16-31-26)20(24)9-8-17-18(28)14-30-22(17)29/h8,18-21,27-28H,9-16H2,1-7H3/b17-8+/t18-,19+,20+,21-,24-,25+,26+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.38E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450149 (CHEMBL4169405) Show SMILES [H][C@]12[#6]-[#6][C@]3([#6]-[#8]3)[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#6]-[#8]-[#6]-3=O)-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])[C@]1([#6])[#6]-[#6]-[#6](=O)[C@@]2([#6])[#6]-[#8]-[#6](-[#6])=O |r| Show InChI InChI=1S/C28H44O7Si/c1-18(29)33-16-27(6)21-11-14-28(17-34-28)22(26(21,5)13-12-23(27)30)10-9-19-20(15-32-24(19)31)35-36(7,8)25(2,3)4/h9,20-22H,10-17H2,1-8H3/b19-9+/t20-,21+,22+,26-,27+,28+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.38E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450144 (CHEMBL4171230) Show SMILES [H][C@]12[#6]-[#6][C@@]3([#6]-[#8]3)[#6@@H](-[#6]\[#6]=[#6]-3/[#6@H](-[#8])-[#6]-[#8]-[#6]-3=O)[C@]1([#6])[#6]-[#6]-[#6@@H](-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])[C@@]2([#6])[#6]-[#8] |r| Show InChI InChI=1S/C26H44O6Si/c1-23(2,3)33(6,7)32-21-11-12-24(4)19(25(21,5)15-27)10-13-26(16-31-26)20(24)9-8-17-18(28)14-30-22(17)29/h8,18-21,27-28H,9-16H2,1-7H3/b17-8+/t18-,19+,20+,21-,24-,25+,26-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.39E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 [702-738,740-752] (Homo sapiens (Human))	BDBM68332 (7-(4-fluorophenyl)-5-methyl-3-phenyl-pyrazolo[1,5-...) Show SMILES Cc1cc(-c2ccc(F)cc2)n2ncc(-c3ccccc3)c2n1 Show InChI InChI=1S/C19H14FN3/c1-13-11-18(15-7-9-16(20)10-8-15)23-19(22-13)17(12-21-23)14-5-3-2-4-6-14/h2-12H,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>5.57E+3	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2BV7F28
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450145 (CHEMBL4163576) Show SMILES [H][C@]12[#6]-[#6]-[#6](=[#6])-[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#6]-[#8]-[#6]-3=O)-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])[C@]1([#6])[#6]-[#6]-[#6@@H](-[#8])[C@@]2([#6])[#6]-[#8] |r| Show InChI InChI=1S/C26H44O5Si/c1-17-9-12-21-25(5,14-13-22(28)26(21,6)16-27)19(17)11-10-18-20(15-30-23(18)29)31-32(7,8)24(2,3)4/h10,19-22,27-28H,1,9,11-16H2,2-8H3/b18-10+/t19-,20-,21+,22-,25+,26+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.68E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450158 (CHEMBL1933811) Show SMILES [H][C@]12[#6]-[#6]-[#6](=[#6])-[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#6]-[#8]-[#6]-3=O)-[#8]-[#6](-[#6])=O)[C@]1([#6])[#6]-[#6]-[#6@@H](-[#8]-[#6](-[#6])=O)[C@@]2([#6])[#6]-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6] |r| Show InChI InChI=1S/C30H48O7Si/c1-19-11-14-25-29(7,23(19)13-12-22-24(36-20(2)31)17-34-27(22)33)16-15-26(37-21(3)32)30(25,8)18-35-38(9,10)28(4,5)6/h12,23-26H,1,11,13-18H2,2-10H3/b22-12+/t23-,24-,25+,26-,29+,30+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human HeLa cells incubated with IFNgamma for 16 hrs followed by compound addition measured afte...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450180 (CHEMBL4177253) Show SMILES [H][C@]12[#6]-[#6][C@@]3([#6]-[#8]3)[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#6]-[#8]-[#6]-3=O)-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])[C@]1([#6])[#6]-[#6]-[#6](=O)[C@@]2([#6])[#6]-[#8]-[#6](-[#6])=O |r| Show InChI InChI=1S/C28H44O7Si/c1-18(29)33-16-27(6)21-11-14-28(17-34-28)22(26(21,5)13-12-23(27)30)10-9-19-20(15-32-24(19)31)35-36(7,8)25(2,3)4/h9,20-22H,10-17H2,1-8H3/b19-9+/t20-,21+,22+,26-,27+,28-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.81E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450143 (CHEMBL4173895) Show SMILES [H][C@]12[#6]-[#6][C@]3([#6]-[#8]3)[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#6]-[#8]-[#6]-3=O)-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])[C@]1([#6])[#6]-[#6]-[#6](=O)[C@@]2([#6])[#6]-[#8] |r| Show InChI InChI=1S/C26H42O6Si/c1-23(2,3)33(6,7)32-18-14-30-22(29)17(18)8-9-20-24(4)12-11-21(28)25(5,15-27)19(24)10-13-26(20)16-31-26/h8,18-20,27H,9-16H2,1-7H3/b17-8+/t18-,19+,20+,24-,25+,26+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human HeLa cells incubated with IFNgamma for 16 hrs followed by compound addition measured afte...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450143 (CHEMBL4173895) Show SMILES [H][C@]12[#6]-[#6][C@]3([#6]-[#8]3)[#6@@H](-[#6]\[#6]=[#6]-3/[#6@@H](-[#6]-[#8]-[#6]-3=O)-[#8][Si;v4]([#6])([#6])C([#6])([#6])[#6])[C@]1([#6])[#6]-[#6]-[#6](=O)[C@@]2([#6])[#6]-[#8] |r| Show InChI InChI=1S/C26H42O6Si/c1-23(2,3)33(6,7)32-18-14-30-22(29)17(18)8-9-20-24(4)12-11-21(28)25(5,15-27)19(24)10-13-26(20)16-31-26/h8,18-20,27H,9-16H2,1-7H3/b17-8+/t18-,19+,20+,24-,25+,26+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.99E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50450175 (CHEMBL4160465) Show SMILES [H][C@]12CCC(=C)[C@@H](C\C=C3/[C@@H](COC3=O)OC(C)=O)[C@]1(C)CCC(=O)[C@@]2(C)CO |r| Show InChI InChI=1S/C22H30O6/c1-13-5-8-18-21(3,10-9-19(25)22(18,4)12-23)16(13)7-6-15-17(28-14(2)24)11-27-20(15)26/h6,16-18,23H,1,5,7-12H2,2-4H3/b15-6+/t16-,17-,18+,21+,22+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a
University of Macau Curated by ChEMBL					Assay Description Inhibition of IL-6 stimulated STAT3 activation in human AD293 cells incubated with IL-6 for 16 hrs followed by compound addition measured after 6 hrs...				Bioorg Med Chem 26: 5053-5061 (2018) Article DOI: 10.1016/j.bmc.2018.09.002 BindingDB Entry DOI: 10.7270/Q2ST7SDK
					More data for this Ligand-Target Pair

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