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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Genome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E] (Dengue virus 2 (strain TSV01)) | BDBM33265 (guanidine, 5) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet  | PC cid PC sid UniChem | Article PubMed | 1.40E+4 | -6.57 | n/a | n/a | n/a | n/a | n/a | 8.5 | 23 |
University of Alabama at Birmingham | Assay Description All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec... | Bioorg Med Chem 13: 257-64 (2005) Article DOI: 10.1016/j.bmc.2004.09.036 BindingDB Entry DOI: 10.7270/Q2QV3JVQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Genome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E] (Dengue virus 2 (strain TSV01)) | BDBM33264 (guanidine, 4) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 2.30E+4 | -6.28 | n/a | n/a | n/a | n/a | n/a | 8.5 | 23 |
University of Alabama at Birmingham | Assay Description All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec... | Bioorg Med Chem 13: 257-64 (2005) Article DOI: 10.1016/j.bmc.2004.09.036 BindingDB Entry DOI: 10.7270/Q2QV3JVQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Genome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E] (Dengue virus 2 (strain TSV01)) | BDBM33261 (biguanidine, 1) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | 4.40E+4 | -5.90 | n/a | n/a | n/a | n/a | n/a | 8.5 | 23 |
University of Alabama at Birmingham | Assay Description All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec... | Bioorg Med Chem 13: 257-64 (2005) Article DOI: 10.1016/j.bmc.2004.09.036 BindingDB Entry DOI: 10.7270/Q2QV3JVQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Genome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E] (Dengue virus 2 (strain TSV01)) | BDBM33260 (biguanidine, 2) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 4.23E+5 | -4.57 | n/a | n/a | n/a | n/a | n/a | 8.5 | 23 |
University of Alabama at Birmingham | Assay Description All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec... | Bioorg Med Chem 13: 257-64 (2005) Article DOI: 10.1016/j.bmc.2004.09.036 BindingDB Entry DOI: 10.7270/Q2QV3JVQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Genome polyprotein [1066-1250,R1182K]/[1394-1440,K1405R,D1408E] (Dengue virus 2 (strain TSV01)) | BDBM33262 (biguanidine, 3) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | 1.78E+6 | -3.72 | n/a | n/a | n/a | n/a | n/a | 8.5 | 23 |
University of Alabama at Birmingham | Assay Description All proteases were assayed by monitoring the cleavage of peptide substrate with fluorescent reporter at room temperature with a microtiter plate spec... | Bioorg Med Chem 13: 257-64 (2005) Article DOI: 10.1016/j.bmc.2004.09.036 BindingDB Entry DOI: 10.7270/Q2QV3JVQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
