Compile Data Set for Download or QSAR

Found 4 hits of ic50 data for polymerid = 7117   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
AMP deaminase 3 (Homo sapiens (Human))	BDBM154583 (6-[4-({[(1S)-1-(isoquinolin-8-yl)ethyl]amino}methy...) Show SMILES C[C@H](NCc1ccc(cc1)-c1ccc(cn1)C(O)=O)c1cccc2ccncc12 |r| Show InChI InChI=1S/C24H21N3O2/c1-16(21-4-2-3-18-11-12-25-15-22(18)21)26-13-17-5-7-19(8-6-17)23-10-9-20(14-27-23)24(28)29/h2-12,14-16,26H,13H2,1H3,(H,28,29)/t16-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	75	n/a	n/a	n/a	n/a	7.4	n/a
AstraZeneca R&D					Assay Description AMPD1 was added to buffer A (50 mM HEPES, 150 mM KCl, 5 mM MgCl2, and 0.5 mMglutathione [pH 7.4]) to a concentration of 10 nM. A substrate mix consis...				Chem Biol 21: 1486-96 (2014) Article DOI: 10.1016/j.chembiol.2014.09.011 BindingDB Entry DOI: 10.7270/Q2M0445M
					More data for this Ligand-Target Pair
AMP deaminase 3 (Homo sapiens (Human))	BDBM50385586 (CHEMBL2042530) Show SMILES OC(=O)c1cc(CCc2cnc3cncnn23)c2CCCCc2c1 Show InChI InChI=1S/C18H18N4O2/c23-18(24)14-7-12-3-1-2-4-16(12)13(8-14)5-6-15-9-20-17-10-19-11-21-22(15)17/h7-11H,1-6H2,(H,23,24)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant AMPD3-1b expressed in Sf9 cells				ACS Med Chem Lett 1: 286-289 (2010) Article DOI: 10.1021/ml100092a BindingDB Entry DOI: 10.7270/Q2X0683X
					More data for this Ligand-Target Pair
AMP deaminase 3 (Homo sapiens (Human))	BDBM154582 (6-[4-({[(1R)-1-(isoquinolin-8-yl)ethyl]amino}methy...) Show SMILES C[C@@H](NCc1ccc(cc1)-c1ccc(cn1)C(O)=O)c1cccc2ccncc12 |r| Show InChI InChI=1S/C24H21N3O2/c1-16(21-4-2-3-18-11-12-25-15-22(18)21)26-13-17-5-7-19(8-6-17)23-10-9-20(14-27-23)24(28)29/h2-12,14-16,26H,13H2,1H3,(H,28,29)/t16-/m1/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	7.4	n/a
AstraZeneca R&D					Assay Description AMPD1 was added to buffer A (50 mM HEPES, 150 mM KCl, 5 mM MgCl2, and 0.5 mMglutathione [pH 7.4]) to a concentration of 10 nM. A substrate mix consis...				Chem Biol 21: 1486-96 (2014) Article DOI: 10.1016/j.chembiol.2014.09.011 BindingDB Entry DOI: 10.7270/Q2M0445M
					More data for this Ligand-Target Pair
AMP deaminase 3 (Homo sapiens (Human))	BDBM50385587 (CHEMBL2042529) Show SMILES OC(=O)c1cccc(CCc2cnc3cncnn23)c1 Show InChI InChI=1S/C14H12N4O2/c19-14(20)11-3-1-2-10(6-11)4-5-12-7-16-13-8-15-9-17-18(12)13/h1-3,6-9H,4-5H2,(H,19,20)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant AMPD3-1b expressed in Sf9 cells				ACS Med Chem Lett 1: 286-289 (2010) Article DOI: 10.1021/ml100092a BindingDB Entry DOI: 10.7270/Q2X0683X
					More data for this Ligand-Target Pair