BindingDB PrimarySearch

Found 19 hits of ki for UniProtKB: P54750
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM168129 (US9073936, 4 \| US9598426, 4) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INTRA-CELLULAR THERAPIES, INC. US Patent					Assay Description Assay: The following phosphodiesterase enzymes may be used: 3′,5′-cyclic-nucleotide-specific bovine brain phosphodiesterase (Sigma, St. L...				US Patent US9598426 (2017) BindingDB Entry DOI: 10.7270/Q29S1T2J
INTRA-CELLULAR THERAPIES, INC. US Patent					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM168129 (US9073936, 4 \| US9598426, 4) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	-13.9	n/a	n/a	n/a	n/a	n/a	7.5	30
INTRA-CELLULAR THERAPIES, INC. US Patent					Assay Description Materials: All chemicals are available from Sigma-Aldrich (St. Louis, Mo.) except for IMAP reagents (reaction buffer, binding buffer, FL-GMP and IMAP...				US Patent US9073936 (2015) BindingDB Entry DOI: 10.7270/Q2348J5T
INTRA-CELLULAR THERAPIES, INC. US Patent					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM168126 (US9073936, 1 \| US9598426, 1) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	-13.4	n/a	n/a	n/a	n/a	n/a	7.5	30
INTRA-CELLULAR THERAPIES, INC. US Patent					Assay Description Materials: All chemicals are available from Sigma-Aldrich (St. Louis, Mo.) except for IMAP reagents (reaction buffer, binding buffer, FL-GMP and IMAP...				US Patent US9073936 (2015) BindingDB Entry DOI: 10.7270/Q2348J5T
INTRA-CELLULAR THERAPIES, INC. US Patent					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM168126 (US9073936, 1 \| US9598426, 1) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INTRA-CELLULAR THERAPIES, INC. US Patent					Assay Description Assay: The following phosphodiesterase enzymes may be used: 3′,5′-cyclic-nucleotide-specific bovine brain phosphodiesterase (Sigma, St. L...				US Patent US9598426 (2017) BindingDB Entry DOI: 10.7270/Q29S1T2J
INTRA-CELLULAR THERAPIES, INC. US Patent					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM168128 (US9073936, 3 \| US9598426, 3) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	-13.2	n/a	n/a	n/a	n/a	n/a	7.5	30
INTRA-CELLULAR THERAPIES, INC. US Patent					Assay Description Materials: All chemicals are available from Sigma-Aldrich (St. Louis, Mo.) except for IMAP reagents (reaction buffer, binding buffer, FL-GMP and IMAP...				US Patent US9073936 (2015) BindingDB Entry DOI: 10.7270/Q2348J5T
INTRA-CELLULAR THERAPIES, INC. US Patent					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM168128 (US9073936, 3 \| US9598426, 3) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INTRA-CELLULAR THERAPIES, INC. US Patent					Assay Description Assay: The following phosphodiesterase enzymes may be used: 3′,5′-cyclic-nucleotide-specific bovine brain phosphodiesterase (Sigma, St. L...				US Patent US9598426 (2017) BindingDB Entry DOI: 10.7270/Q29S1T2J
INTRA-CELLULAR THERAPIES, INC. US Patent					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM168129 (US9073936, 4 \| US9598426, 4) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-13.0	n/a	n/a	n/a	n/a	n/a	7.5	30
INTRA-CELLULAR THERAPIES, INC. US Patent					Assay Description Materials: All chemicals are available from Sigma-Aldrich (St. Louis, Mo.) except for IMAP reagents (reaction buffer, binding buffer, FL-GMP and IMAP...				US Patent US9073936 (2015) BindingDB Entry DOI: 10.7270/Q2348J5T
INTRA-CELLULAR THERAPIES, INC. US Patent					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM168127 (US9073936, 2 \| US9598426, 2) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	-12.9	n/a	n/a	n/a	n/a	n/a	7.5	30
INTRA-CELLULAR THERAPIES, INC. US Patent					Assay Description Materials: All chemicals are available from Sigma-Aldrich (St. Louis, Mo.) except for IMAP reagents (reaction buffer, binding buffer, FL-GMP and IMAP...				US Patent US9073936 (2015) BindingDB Entry DOI: 10.7270/Q2348J5T
INTRA-CELLULAR THERAPIES, INC. US Patent					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM168127 (US9073936, 2 \| US9598426, 2) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INTRA-CELLULAR THERAPIES, INC. US Patent					Assay Description Assay: The following phosphodiesterase enzymes may be used: 3′,5′-cyclic-nucleotide-specific bovine brain phosphodiesterase (Sigma, St. L...				US Patent US9598426 (2017) BindingDB Entry DOI: 10.7270/Q29S1T2J
INTRA-CELLULAR THERAPIES, INC. US Patent					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM168126 (US9073936, 1 \| US9598426, 1) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1	-12.5	n/a	n/a	n/a	n/a	n/a	7.5	30
INTRA-CELLULAR THERAPIES, INC. US Patent					Assay Description Materials: All chemicals are available from Sigma-Aldrich (St. Louis, Mo.) except for IMAP reagents (reaction buffer, binding buffer, FL-GMP and IMAP...				US Patent US9073936 (2015) BindingDB Entry DOI: 10.7270/Q2348J5T
INTRA-CELLULAR THERAPIES, INC. US Patent					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM168128 (US9073936, 3 \| US9598426, 3) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	-11.6	n/a	n/a	n/a	n/a	n/a	7.5	30
INTRA-CELLULAR THERAPIES, INC. US Patent					Assay Description Materials: All chemicals are available from Sigma-Aldrich (St. Louis, Mo.) except for IMAP reagents (reaction buffer, binding buffer, FL-GMP and IMAP...				US Patent US9073936 (2015) BindingDB Entry DOI: 10.7270/Q2348J5T
INTRA-CELLULAR THERAPIES, INC. US Patent					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM168127 (US9073936, 2 \| US9598426, 2) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4	-11.6	n/a	n/a	n/a	n/a	n/a	7.5	30
INTRA-CELLULAR THERAPIES, INC. US Patent					Assay Description Materials: All chemicals are available from Sigma-Aldrich (St. Louis, Mo.) except for IMAP reagents (reaction buffer, binding buffer, FL-GMP and IMAP...				US Patent US9073936 (2015) BindingDB Entry DOI: 10.7270/Q2348J5T
INTRA-CELLULAR THERAPIES, INC. US Patent					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50362046 (CHEMBL1940056) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]cAMP from PDE1A3 by competitive binding assay				Bioorg Med Chem Lett 22: 235-9 (2011) Article DOI: 10.1016/j.bmcl.2011.11.023 BindingDB Entry DOI: 10.7270/Q2862GWC
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50362048 (CHEMBL1940058) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]cAMP from PDE1A3 by competitive binding assay				Bioorg Med Chem Lett 22: 235-9 (2011) Article DOI: 10.1016/j.bmcl.2011.11.023 BindingDB Entry DOI: 10.7270/Q2862GWC
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50362033 (CHEMBL1939912) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]cAMP from PDE1A3 by competitive binding assay				Bioorg Med Chem Lett 22: 235-9 (2011) Article DOI: 10.1016/j.bmcl.2011.11.023 BindingDB Entry DOI: 10.7270/Q2862GWC
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50362043 (CHEMBL1940053) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]cAMP from PDE1A3 by competitive binding assay				Bioorg Med Chem Lett 22: 235-9 (2011) Article DOI: 10.1016/j.bmcl.2011.11.023 BindingDB Entry DOI: 10.7270/Q2862GWC
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50362036 (CHEMBL1939915) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]cAMP from PDE1A3 by competitive binding assay				Bioorg Med Chem Lett 22: 235-9 (2011) Article DOI: 10.1016/j.bmcl.2011.11.023 BindingDB Entry DOI: 10.7270/Q2862GWC
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50362035 (CHEMBL1939914) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]cAMP from PDE1A3 by competitive binding assay				Bioorg Med Chem Lett 22: 235-9 (2011) Article DOI: 10.1016/j.bmcl.2011.11.023 BindingDB Entry DOI: 10.7270/Q2862GWC
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50362047 (CHEMBL1940057) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]cAMP from PDE1A3 by competitive binding assay				Bioorg Med Chem Lett 22: 235-9 (2011) Article DOI: 10.1016/j.bmcl.2011.11.023 BindingDB Entry DOI: 10.7270/Q2862GWC
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair