Compile Data Set for Download or QSAR

Found 36 hits of ic50 for UniProtKB: P35354   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173509 (3-(4-Ethoxyphenyl)-1-(4-methanesulfonylphenyl)-5-(...) Show SMILES CCOc1ccc(cc1)C1=NN(C(C1)c1ccc(cc1)C(F)(F)F)c1ccc(cc1)S(C)(=O)=O |t:10| Show InChI InChI=1S/C25H23F3N2O3S/c1-3-33-21-12-6-17(7-13-21)23-16-24(18-4-8-19(9-5-18)25(26,27)28)30(29-23)20-10-14-22(15-11-20)34(2,31)32/h4-15,24H,3,16H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173518 (1-(4-Methanesulfonylphenyl)-3-(4-hydroxyphenyl)-5-...) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(cc1)C(F)(F)F)-c1ccc(O)cc1 Show InChI InChI=1S/C23H17F3N2O3S/c1-32(30,31)20-12-8-18(9-13-20)28-22(16-2-6-17(7-3-16)23(24,25)26)14-21(27-28)15-4-10-19(29)11-5-15/h2-14,29H,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173507 (1-(4-Methanesulfonylphenyl)-3-(p-tolyl)-5-(4-trifl...) Show SMILES Cc1ccc(cc1)C1=NN(C(C1)c1ccc(cc1)C(F)(F)F)c1ccc(cc1)S(C)(=O)=O |t:8| Show InChI InChI=1S/C24H21F3N2O2S/c1-16-3-5-17(6-4-16)22-15-23(18-7-9-19(10-8-18)24(25,26)27)29(28-22)20-11-13-21(14-12-20)32(2,30)31/h3-14,23H,15H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni Suef University					Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...				Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173529 (1-(4-Aminosulfonylphenyl)-3-(3,4-difluorophenyl)-5...) Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(cc1)C(F)(F)F)-c1ccc(F)c(F)c1 Show InChI InChI=1S/C22H14F5N3O2S/c23-18-10-3-14(11-19(18)24)20-12-21(13-1-4-15(5-2-13)22(25,26)27)30(29-20)16-6-8-17(9-7-16)33(28,31)32/h1-12H,(H2,28,31,32)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173514 (1-(4-Aminosulfonylphenyl)-3-(4-methoxyphenyl)-5-(4...) Show SMILES COc1ccc(cc1)C1=NN(C(C1)c1ccc(cc1)C(F)(F)F)c1ccc(cc1)S(N)(=O)=O |t:9| Show InChI InChI=1S/C23H20F3N3O3S/c1-32-19-10-4-15(5-11-19)21-14-22(16-2-6-17(7-3-16)23(24,25)26)29(28-21)18-8-12-20(13-9-18)33(27,30)31/h2-13,22H,14H2,1H3,(H2,27,30,31)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173523 (3-(3,4-Difluorophenyl)-1-(4-methanesulfonylphenyl)...) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(cc1)C(F)(F)F)-c1ccc(F)c(F)c1 Show InChI InChI=1S/C23H15F5N2O2S/c1-33(31,32)18-9-7-17(8-10-18)30-22(14-2-5-16(6-3-14)23(26,27)28)13-21(29-30)15-4-11-19(24)20(25)12-15/h2-13H,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173521 (3-(4-ethoxyphenyl)-1-(4-methanesulfonylphenyl)-5-[...) Show SMILES CCOc1ccc(cc1)-c1cc(-c2ccc(cc2)C(F)(F)F)n(n1)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C25H21F3N2O3S/c1-3-33-21-12-6-17(7-13-21)23-16-24(18-4-8-19(9-5-18)25(26,27)28)30(29-23)20-10-14-22(15-11-20)34(2,31)32/h4-16H,3H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.71E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173512 (1-(4-Aminosulfonylphenyl)-3-(4-hydroxyphenyl)-5-(4...) Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccc(cc1)C(F)(F)F)c1ccc(O)cc1 |c:12| Show InChI InChI=1S/C22H18F3N3O3S/c23-22(24,25)16-5-1-15(2-6-16)21-13-20(14-3-9-18(29)10-4-14)27-28(21)17-7-11-19(12-8-17)32(26,30)31/h1-12,21,29H,13H2,(H2,26,30,31)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM175286 (3-(4-Aminosulfonylphenylamino)-2-(4-fluorophenyl)-...) Show SMILES CC1SC(N(Nc2ccc(cc2)S(N)(=O)=O)C1=O)c1ccc(F)cc1 Show InChI InChI=1S/C16H16FN3O3S2/c1-10-15(21)20(16(24-10)11-2-4-12(17)5-3-11)19-13-6-8-14(9-7-13)25(18,22)23/h2-10,16,19H,1H3,(H2,18,22,23)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni Suef University					Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...				Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173516 (1-(4-Aminosulfonylphenyl)-3-(4-fluorophenyl)-5-(4-...) Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccc(cc1)C(F)(F)F)c1ccc(F)cc1 |c:12| Show InChI InChI=1S/C22H17F4N3O2S/c23-17-7-3-14(4-8-17)20-13-21(15-1-5-16(6-2-15)22(24,25)26)29(28-20)18-9-11-19(12-10-18)32(27,30)31/h1-12,21H,13H2,(H2,27,30,31)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM175285 (3-(4-Aminosulfonylphenylamino)-2-(4-chlorophenyl)-...) Show SMILES CC1SC(N(Nc2ccc(cc2)S(N)(=O)=O)C1=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C16H16ClN3O3S2/c1-10-15(21)20(16(24-10)11-2-4-12(17)5-3-11)19-13-6-8-14(9-7-13)25(18,22)23/h2-10,16,19H,1H3,(H2,18,22,23)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni Suef University					Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...				Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173527 (1-(4-Aminosulfonylphenyl)-3-(4-ethoxyphenyl)-5-(4-...) Show SMILES CCOc1ccc(cc1)-c1cc(-c2ccc(cc2)C(F)(F)F)n(n1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C24H20F3N3O3S/c1-2-33-20-11-5-16(6-12-20)22-15-23(17-3-7-18(8-4-17)24(25,26)27)30(29-22)19-9-13-21(14-10-19)34(28,31)32/h3-15H,2H2,1H3,(H2,28,31,32)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173519 (1-(4-Methanesulfonylphenyl)-3-(p-tolyl)-5-(4-trifl...) Show SMILES Cc1ccc(cc1)-c1cc(-c2ccc(cc2)C(F)(F)F)n(n1)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C24H19F3N2O2S/c1-16-3-5-17(6-4-16)22-15-23(18-7-9-19(10-8-18)24(25,26)27)29(28-22)20-11-13-21(14-12-20)32(2,30)31/h3-15H,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173524 (1-(4-Aminosulfonylphenyl)-3-(4-hydroxyphenyl)-5-(4...) Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(cc1)C(F)(F)F)-c1ccc(O)cc1 Show InChI InChI=1S/C22H16F3N3O3S/c23-22(24,25)16-5-1-15(2-6-16)21-13-20(14-3-9-18(29)10-4-14)27-28(21)17-7-11-19(12-8-17)32(26,30)31/h1-13,29H,(H2,26,30,31)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM60580 (3-(4-Aminosulfonylphenylamino)-5-methyl-2-(4-trifl...) Show SMILES CC1SC(N(Nc2ccc(cc2)S(N)(=O)=O)C1=O)c1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H16F3N3O3S2/c1-10-15(24)23(22-13-6-8-14(9-7-13)28(21,25)26)16(27-10)11-2-4-12(5-3-11)17(18,19)20/h2-10,16,22H,1H3,(H2,21,25,26)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni Suef University					Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...				Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173517 (1-(4-Aminosulfonylphenyl)-3-(3,4-difluorophenyl)-5...) Show SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccc(cc1)C(F)(F)F)c1ccc(F)c(F)c1 |c:12| Show InChI InChI=1S/C22H16F5N3O2S/c23-18-10-3-14(11-19(18)24)20-12-21(13-1-4-15(5-2-13)22(25,26)27)30(29-20)16-6-8-17(9-7-16)33(28,31)32/h1-11,21H,12H2,(H2,28,31,32)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173522 (3-(4-Fluorophenyl)-1-(4-methanesulfonylphenyl)-5-(...) Show SMILES CS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(cc1)C(F)(F)F)-c1ccc(F)cc1 Show InChI InChI=1S/C23H16F4N2O2S/c1-32(30,31)20-12-10-19(11-13-20)29-22(16-2-6-17(7-3-16)23(25,26)27)14-21(28-29)15-4-8-18(24)9-5-15/h2-14H,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173515 (1-(4-Aminosulfonylphenyl)-3-(4-ethoxyphenyl)-5-(4-...) Show SMILES CCOc1ccc(cc1)C1=NN(C(C1)c1ccc(cc1)C(F)(F)F)c1ccc(cc1)S(N)(=O)=O |t:10| Show InChI InChI=1S/C24H22F3N3O3S/c1-2-33-20-11-5-16(6-12-20)22-15-23(17-3-7-18(8-4-17)24(25,26)27)30(29-22)19-9-13-21(14-10-19)34(28,31)32/h3-14,23H,2,15H2,1H3,(H2,28,31,32)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM175280 (2-(4-(4-Nitrophenyl)thiazol-2-ylimino)thiazolidin-...) Show SMILES [O-][N+](=O)c1ccc(cc1)-c1csc(N=C2NC(=O)CS2)n1 |w:13.13| Show InChI InChI=1S/C12H8N4O3S2/c17-10-6-21-12(14-10)15-11-13-9(5-20-11)7-1-3-8(4-2-7)16(18)19/h1-5H,6H2,(H,13,14,15,17)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni Suef University					Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...				Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173510 (3-(4-Fluorophenyl)-1-(4-Methanesulfonylphenyl)-5-(...) Show SMILES CS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccc(cc1)C(F)(F)F)c1ccc(F)cc1 |c:12| Show InChI InChI=1S/C23H18F4N2O2S/c1-32(30,31)20-12-10-19(11-13-20)29-22(16-2-6-17(7-3-16)23(25,26)27)14-21(28-29)15-4-8-18(24)9-5-15/h2-13,22H,14H2,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM175284 (3-(4-Aminosulfonylphenylamino)-5-methyl-2-(4-methy...) Show SMILES CC1SC(N(Nc2ccc(cc2)S(N)(=O)=O)C1=O)c1ccc(C)cc1 Show InChI InChI=1S/C17H19N3O3S2/c1-11-3-5-13(6-4-11)17-20(16(21)12(2)24-17)19-14-7-9-15(10-8-14)25(18,22)23/h3-10,12,17,19H,1-2H3,(H2,18,22,23)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni Suef University					Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...				Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM175282 (2-(4-(4-Methanesulfonamidophenyl)thiazol-2-ylimino...) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1csc(\N=C2\NC(=O)CS2)n1 Show InChI InChI=1S/C13H12N4O3S3/c1-23(19,20)17-9-4-2-8(3-5-9)10-6-21-12(14-10)16-13-15-11(18)7-22-13/h2-6,17H,7H2,1H3,(H,14,15,16,18)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni Suef University					Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...				Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173520 (1-(4-methanesulfonylphenyl)-3-(4-methoxyphenyl)-5-...) Show SMILES COc1ccc(cc1)-c1cc(-c2ccc(cc2)C(F)(F)F)n(n1)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C24H19F3N2O3S/c1-32-20-11-5-16(6-12-20)22-15-23(17-3-7-18(8-4-17)24(25,26)27)29(28-22)19-9-13-21(14-10-19)33(2,30)31/h3-15H,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173525 (1-(4-Aminosulfonylphenyl)-3-(p-tolyl)-5-(4-trifluo...) Show SMILES Cc1ccc(cc1)-c1cc(-c2ccc(cc2)C(F)(F)F)n(n1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C23H18F3N3O2S/c1-15-2-4-16(5-3-15)21-14-22(17-6-8-18(9-7-17)23(24,25)26)29(28-21)19-10-12-20(13-11-19)32(27,30)31/h2-14H,1H3,(H2,27,30,31)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM175281 (2-(4-(4-Isobutylphenyl)thiazol-2-ylimino)thiazolid...) Show SMILES CC(C)Cc1ccc(cc1)-c1csc(N=C2NC(=O)CS2)n1 |w:14.14| Show InChI InChI=1S/C16H17N3OS2/c1-10(2)7-11-3-5-12(6-4-11)13-8-21-15(17-13)19-16-18-14(20)9-22-16/h3-6,8,10H,7,9H2,1-2H3,(H,17,18,19,20)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni Suef University					Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...				Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173506 (1-(4-Methanesulfonylphenyl)-3-(4-hydroxyphenyl)-5-...) Show SMILES CS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccc(cc1)C(F)(F)F)c1ccc(O)cc1 |c:12| Show InChI InChI=1S/C23H19F3N2O3S/c1-32(30,31)20-12-8-18(9-13-20)28-22(16-2-6-17(7-3-16)23(24,25)26)14-21(27-28)15-4-10-19(29)11-5-15/h2-13,22,29H,14H2,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173528 (1-(4-Aminosulfonylphenyl)-3-(4-fluorophenyl)-5-(4-...) Show SMILES NS(=O)(=O)c1ccc(cc1)-n1nc(cc1-c1ccc(cc1)C(F)(F)F)-c1ccc(F)cc1 Show InChI InChI=1S/C22H15F4N3O2S/c23-17-7-3-14(4-8-17)20-13-21(15-1-5-16(6-2-15)22(24,25)26)29(28-20)18-9-11-19(12-10-18)32(27,30)31/h1-13H,(H2,27,30,31)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM50009859 ((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...) Show SMILES CC(C)Cc1ccc(cc1)C(C)C(O)=O Show InChI InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173526 (1-(4-Aminosulfonylphenyl)-3-(4-methoxyphenyl)-5-(4...) Show SMILES COc1ccc(cc1)-c1cc(-c2ccc(cc2)C(F)(F)F)n(n1)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C23H18F3N3O3S/c1-32-19-10-4-15(5-11-19)21-14-22(16-2-6-17(7-3-16)23(24,25)26)29(28-21)18-8-12-20(13-9-18)33(27,30)31/h2-14H,1H3,(H2,27,30,31)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173513 (1-(4-Aminosulfonylphenyl)-3-(p-tolyl)-5-(4-trifluo...) Show SMILES Cc1ccc(cc1)C1=NN(C(C1)c1ccc(cc1)C(F)(F)F)c1ccc(cc1)S(N)(=O)=O |t:8| Show InChI InChI=1S/C23H20F3N3O2S/c1-15-2-4-16(5-3-15)21-14-22(17-6-8-18(9-7-17)23(24,25)26)29(28-21)19-10-12-20(13-11-19)32(27,30)31/h2-13,22H,14H2,1H3,(H2,27,30,31)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM175283 (3-(4-Aminosulfonylphenylamino)-5-methyl-2-phenyl-4...) Show SMILES CC1SC(N(Nc2ccc(cc2)S(N)(=O)=O)C1=O)c1ccccc1 Show InChI InChI=1S/C16H17N3O3S2/c1-11-15(20)19(16(23-11)12-5-3-2-4-6-12)18-13-7-9-14(10-8-13)24(17,21)22/h2-11,16,18H,1H3,(H2,17,21,22)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni Suef University					Assay Description The ability of the tested compounds to inhibit both COX-1 and COX-2 isozymes was measured using colorimetric COX (ovine) Inhibitor Screening Assay Ki...				Bioorg Chem 64: 1-12 (2016) Article DOI: 10.1016/j.bioorg.2015.11.001 BindingDB Entry DOI: 10.7270/Q24M939R
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173511 (3-(3,4-Difluoroluorophenyl)-1-(4-methanesulfonylph...) Show SMILES CS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1ccc(cc1)C(F)(F)F)c1ccc(F)c(F)c1 |c:12| Show InChI InChI=1S/C23H17F5N2O2S/c1-33(31,32)18-9-7-17(8-10-18)30-22(14-2-5-16(6-3-14)23(26,27)28)13-21(29-30)15-4-11-19(24)20(25)12-15/h2-12,22H,13H2,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM173508 (1-(4-Methanesulfonylphenyl)-3-(4-methoxyphenyl)-5-...) Show SMILES COc1ccc(cc1)C1=NN(C(C1)c1ccc(cc1)C(F)(F)F)c1ccc(cc1)S(C)(=O)=O |t:9| Show InChI InChI=1S/C24H21F3N2O3S/c1-32-20-11-5-16(6-12-20)22-15-23(17-3-7-18(8-4-17)24(25,26)27)29(28-22)19-9-13-21(14-10-19)33(2,30)31/h3-14,23H,15H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [E165G] (Homo sapiens (Human))	BDBM22360 (2-(acetyloxy)benzoate | 2-(acetyloxy)benzoic acid ...) Show SMILES CC(=O)Oc1ccccc1C(O)=O Show InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Beni-Suef University					Assay Description The ability of the test compounds to inhibit ovine COX01 and human recombinant COX-2 was determined using an enzyme immuno assay (EIA) kit according ...				Bioorg Chem 63: 13-23 (2015) Article DOI: 10.1016/j.bioorg.2015.09.002 BindingDB Entry DOI: 10.7270/Q28G8JGV
					More data for this Ligand-Target Pair