Compile Data Set for Download or QSAR

Found 18 hits of ic50 for UniProtKB: P0A031   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division protein FtsZ (Staphylococcus aureus)	BDBM50079356 (CHEMBL511201) Show SMILES NC(=O)c1c(F)ccc(OCc2nc3cc(Cl)cnc3s2)c1F Show InChI InChI=1S/C14H8ClF2N3O2S/c15-6-3-8-14(19-4-6)23-10(20-8)5-22-9-2-1-7(16)11(12(9)17)13(18)21/h1-4H,5H2,(H2,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cell division protein FtsZ (Staphylococcus aureus)	BDBM50079356 (CHEMBL511201) Show SMILES NC(=O)c1c(F)ccc(OCc2nc3cc(Cl)cnc3s2)c1F Show InChI InChI=1S/C14H8ClF2N3O2S/c15-6-3-8-14(19-4-6)23-10(20-8)5-22-9-2-1-7(16)11(12(9)17)13(18)21/h1-4H,5H2,(H2,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus FtsZ GTPase activity				Eur J Med Chem 95: 1-15 (2015) Article DOI: 10.1016/j.ejmech.2015.03.026 BindingDB Entry DOI: 10.7270/Q2S75J14
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cell division protein FtsZ (Staphylococcus aureus)	BDBM50079356 (CHEMBL511201) Show SMILES NC(=O)c1c(F)ccc(OCc2nc3cc(Cl)cnc3s2)c1F Show InChI InChI=1S/C14H8ClF2N3O2S/c15-6-3-8-14(19-4-6)23-10(20-8)5-22-9-2-1-7(16)11(12(9)17)13(18)21/h1-4H,5H2,(H2,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
Prolysis Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus FtsZ GTPase activity				Science 321: 1673-5 (2008) Article DOI: 10.1126/science.1159961 BindingDB Entry DOI: 10.7270/Q2HX1GG1
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cell division protein FtsZ (Staphylococcus aureus)	BDBM50079356 (CHEMBL511201) Show SMILES NC(=O)c1c(F)ccc(OCc2nc3cc(Cl)cnc3s2)c1F Show InChI InChI=1S/C14H8ClF2N3O2S/c15-6-3-8-14(19-4-6)23-10(20-8)5-22-9-2-1-7(16)11(12(9)17)13(18)21/h1-4H,5H2,(H2,18,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
Stony Brook University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus FtsZ GTPase activity				Bioorg Med Chem 24: 6354-6369 (2016) Article DOI: 10.1016/j.bmc.2016.05.003 BindingDB Entry DOI: 10.7270/Q2SN0BZ0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cell division protein FtsZ (Staphylococcus aureus)	BDBM50203126 (3,4-dimethoxy-6,7-dihydro-[1,3]dioxolo[4,5-g]pyrid...) Show SMILES COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OC Show InChI InChI=1S/C20H18NO4/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2/h3-4,7-10H,5-6,11H2,1-2H3/q+1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Staphylococcus aureus)	BDBM50201769 (CHEMBL3416823) Show SMILES [H][C@@]12CCN(C[C@@H]1c1cc(nc(n1)-c1ccncc1)C(CC)CC)[C@@H](CN)C2 |r| Show InChI InChI=1S/C22H31N5/c1-3-15(4-2)20-12-21(26-22(25-20)16-5-8-24-9-6-16)19-14-27-10-7-17(19)11-18(27)13-23/h5-6,8-9,12,15,17-19H,3-4,7,10-11,13-14,23H2,1-2H3/t17-,18+,19-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
Stony Brook University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus ATCC 29213 N-terminal His6-tagged FtsZ GTPase activity expressed in Escherichia coli BL21(DE3) assessed as reduct...				Bioorg Med Chem 24: 6354-6369 (2016) Article DOI: 10.1016/j.bmc.2016.05.003 BindingDB Entry DOI: 10.7270/Q2SN0BZ0
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Staphylococcus aureus)	BDBM50201769 (CHEMBL3416823) Show SMILES [H][C@@]12CCN(C[C@@H]1c1cc(nc(n1)-c1ccncc1)C(CC)CC)[C@@H](CN)C2 |r| Show InChI InChI=1S/C22H31N5/c1-3-15(4-2)20-12-21(26-22(25-20)16-5-8-24-9-6-16)19-14-27-10-7-17(19)11-18(27)13-23/h5-6,8-9,12,15,17-19H,3-4,7,10-11,13-14,23H2,1-2H3/t17-,18+,19-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	3.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Staphylococcus aureus)	BDBM50320891 (9-O-[3-(4-Chloro-phenoxyl)propyl]-berberine bromid...) Show SMILES COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OCCCOc1ccc(Cl)cc1 Show InChI InChI=1S/C28H25ClNO5/c1-31-25-8-3-18-13-24-22-15-27-26(34-17-35-27)14-19(22)9-10-30(24)16-23(18)28(25)33-12-2-11-32-21-6-4-20(29)5-7-21/h3-8,13-16H,2,9-12,17H2,1H3/q+1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	3.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Staphylococcus aureus)	BDBM50439496 (CHEMBL2418096 | US9169182, J23) Show SMILES COc1cc(C\C=C(\Cl)Cc2cc(O)cc(O)c2)c(OC)cc1Cl Show InChI InChI=1S/C18H18Cl2O4/c1-23-17-10-16(20)18(24-2)8-12(17)3-4-13(19)5-11-6-14(21)9-15(22)7-11/h4,6-10,21-22H,3,5H2,1-2H3/b13-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Shandong University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus FtsZ GTPase activity				Eur J Med Chem 95: 1-15 (2015) Article DOI: 10.1016/j.ejmech.2015.03.026 BindingDB Entry DOI: 10.7270/Q2S75J14
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Staphylococcus aureus)	BDBM50439496 (CHEMBL2418096 | US9169182, J23) Show SMILES COc1cc(C\C=C(\Cl)Cc2cc(O)cc(O)c2)c(OC)cc1Cl Show InChI InChI=1S/C18H18Cl2O4/c1-23-17-10-16(20)18(24-2)8-12(17)3-4-13(19)5-11-6-14(21)9-15(22)7-11/h4,6-10,21-22H,3,5H2,1-2H3/b13-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibition of recombinant Staphylococcus aureus FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic pho...				Bioorg Med Chem 21: 5673-8 (2013) Article DOI: 10.1016/j.bmc.2013.07.033 BindingDB Entry DOI: 10.7270/Q2057HC4
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Staphylococcus aureus)	BDBM50439496 (CHEMBL2418096 | US9169182, J23) Show SMILES COc1cc(C\C=C(\Cl)Cc2cc(O)cc(O)c2)c(OC)cc1Cl Show InChI InChI=1S/C18H18Cl2O4/c1-23-17-10-16(20)18(24-2)8-12(17)3-4-13(19)5-11-6-14(21)9-15(22)7-11/h4,6-10,21-22H,3,5H2,1-2H3/b13-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	6.5	25
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES; UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION US Patent					Assay Description The bacterial cytoskeletal protein FtsZ is a GTPase and has structural homology to the eukaryotic cytoskeletal protein tubulin, but lacks significant...				US Patent US9169182 (2015) BindingDB Entry DOI: 10.7270/Q22Z149Z
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Staphylococcus aureus)	BDBM50608376 (CHEMBL3416822) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	5.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Staphylococcus aureus)	BDBM50439495 (CHEMBL2418095) Show SMILES Oc1cc(O)c2Oc3cc(C\C=C(Cl)/Cc4cc(O)c(Oc5cc(C\C=C(Cl)/Cc2c1)c(O)cc5Cl)c(O)c4)c(O)cc3Cl |t:11,25| Show InChI InChI=1S/C32H24Cl4O8/c33-19-3-1-16-10-29(22(35)13-24(16)38)43-31-18(9-21(37)12-28(31)42)8-20(34)4-2-17-11-30(23(36)14-25(17)39)44-32-26(40)6-15(5-19)7-27(32)41/h3-4,6-7,9-14,37-42H,1-2,5,8H2/b19-3+,20-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibition of recombinant Staphylococcus aureus FtsZ GTPase activity expressed in Escherichia coli BL21 (DE3) assessed as production of inorganic pho...				Bioorg Med Chem 21: 5673-8 (2013) Article DOI: 10.1016/j.bmc.2013.07.033 BindingDB Entry DOI: 10.7270/Q2057HC4
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Staphylococcus aureus)	BDBM50608375 (CHEMBL3416821) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	7.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Staphylococcus aureus)	BDBM50320891 (9-O-[3-(4-Chloro-phenoxyl)propyl]-berberine bromid...) Show SMILES COc1ccc2cc3-c4cc5OCOc5cc4CC[n+]3cc2c1OCCCOc1ccc(Cl)cc1 Show InChI InChI=1S/C28H25ClNO5/c1-31-25-8-3-18-13-24-22-15-27-26(34-17-35-27)14-19(22)9-10-30(24)16-23(18)28(25)33-12-2-11-32-21-6-4-20(29)5-7-21/h3-8,13-16H,2,9-12,17H2,1H3/q+1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.74E+4	n/a	n/a	n/a	n/a	n/a	n/a
Stony Brook University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus N-terminal His6-tagged FtsZ GTPase activity expressed in Escherichia coli BL21(DE3) preincubated for 10 mins foll...				Bioorg Med Chem 24: 6354-6369 (2016) Article DOI: 10.1016/j.bmc.2016.05.003 BindingDB Entry DOI: 10.7270/Q2SN0BZ0
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Staphylococcus aureus)	BDBM186046 (US9169182, J24) Show SMILES Oc1cc(O)cc(C\C(Cl)=C/Cc2cc(O)c(Cl)cc2O)c1 Show InChI InChI=1S/C16H14Cl2O4/c17-11(3-9-4-12(19)7-13(20)5-9)2-1-10-6-16(22)14(18)8-15(10)21/h2,4-8,19-22H,1,3H2/b11-2+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	8.80E+4	n/a	n/a	n/a	n/a	6.5	25
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES; UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION US Patent					Assay Description The bacterial cytoskeletal protein FtsZ is a GTPase and has structural homology to the eukaryotic cytoskeletal protein tubulin, but lacks significant...				US Patent US9169182 (2015) BindingDB Entry DOI: 10.7270/Q22Z149Z
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Staphylococcus aureus)	BDBM50201768 (CHEMBL2413354) Show SMILES CC(C)(C)c1ccc(cc1)-c1ncnc2c(CNC(N)=N)cccc12 Show InChI InChI=1S/C20H23N5/c1-20(2,3)15-9-7-13(8-10-15)17-16-6-4-5-14(11-23-19(21)22)18(16)25-12-24-17/h4-10,12H,11H2,1-3H3,(H4,21,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.17E+5	n/a	n/a	n/a	n/a	n/a	n/a
Stony Brook University Curated by ChEMBL					Assay Description Inhibition of Staphylococcus aureus ATCC 29213 N-terminal His6-tagged FtsZ GTPase activity expressed in Escherichia coli BL21(DE3) assessed as reduct...				Bioorg Med Chem 24: 6354-6369 (2016) Article DOI: 10.1016/j.bmc.2016.05.003 BindingDB Entry DOI: 10.7270/Q2SN0BZ0
					More data for this Ligand-Target Pair
Cell division protein FtsZ (Staphylococcus aureus)	BDBM50608374 (CHEMBL3416820) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	3.17E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair