Compile Data Set for Download or QSAR

Found 22 hits of ec50 for UniProtKB: P42681   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434515 (US10562893, Compound 2) Show SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3ccc(s3)C(F)F)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C |r| Show InChI InChI=1S/C29H31F2N5O2S/c1-6-25(37)33-19-8-7-9-20(15-19)36-22-11-10-18(16-32-17(2)29(3,4)5)14-21(22)34-28(36)35-27(38)24-13-12-23(39-24)26(30)31/h6-15,17,26,32H,1,16H2,2-5H3,(H,33,37)(H,34,35,38)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434534 (US10562893, Compound 77) Show SMILES C[C@H](N1CCOCC1)C(=O)N(C)c1ccc2n(c(NC(=O)c3ccc(s3)C(F)F)nc2c1)-c1cccc(NC(=O)C=C)c1 |r| Show InChI InChI=1S/C30H30F2N6O4S/c1-4-26(39)33-19-6-5-7-21(16-19)38-23-9-8-20(36(3)29(41)18(2)37-12-14-42-15-13-37)17-22(23)34-30(38)35-28(40)25-11-10-24(43-25)27(31)32/h4-11,16-18,27H,1,12-15H2,2-3H3,(H,33,39)(H,34,35,40)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434533 (US10562893, Compound 68) Show SMILES C[C@H](NCc1ccc2n([C@@H]3CCC[C@@H](C3)NC(=O)C=C)c(NC(=O)c3ccc(s3)C(F)F)nc2c1)C(C)(C)C |r| Show InChI InChI=1S/C29H37F2N5O2S/c1-6-25(37)33-19-8-7-9-20(15-19)36-22-11-10-18(16-32-17(2)29(3,4)5)14-21(22)34-28(36)35-27(38)24-13-12-23(39-24)26(30)31/h6,10-14,17,19-20,26,32H,1,7-9,15-16H2,2-5H3,(H,33,37)(H,34,35,38)/t17-,19-,20+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434531 (US10562893, Compound 50) Show SMILES FC(F)c1ccc(s1)C(=O)Nc1nc2cc(CN3CCOCC3)ccc2n1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C27H25F2N5O3S/c1-2-24(35)30-18-4-3-5-19(15-18)34-21-7-6-17(16-33-10-12-37-13-11-33)14-20(21)31-27(34)32-26(36)23-9-8-22(38-23)25(28)29/h2-9,14-15,25H,1,10-13,16H2,(H,30,35)(H,31,32,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434530 (US10562893, Compound 43) Show SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3ccns3)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C |r| Show InChI InChI=1S/C27H30N6O2S/c1-6-24(34)30-19-8-7-9-20(15-19)33-22-11-10-18(16-28-17(2)27(3,4)5)14-21(22)31-26(33)32-25(35)23-12-13-29-36-23/h6-15,17,28H,1,16H2,2-5H3,(H,30,34)(H,31,32,35)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434528 (US10562893, Compound 38) Show SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3ccno3)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C |r| Show InChI InChI=1S/C27H30N6O3/c1-6-24(34)30-19-8-7-9-20(15-19)33-22-11-10-18(16-28-17(2)27(3,4)5)14-21(22)31-26(33)32-25(35)23-12-13-29-36-23/h6-15,17,28H,1,16H2,2-5H3,(H,30,34)(H,31,32,35)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434527 (US10562893, Compound 31) Show SMILES O[C@H]1CC[C@@H](CC1)NCc1ccc2n(c(NC(=O)c3ccc(s3)C(F)F)nc2c1)-c1cccc(NC(=O)C=C)c1 |r,wU:4.7,wD:1.0,(-10.96,5.47,;-9.63,4.7,;-9.63,3.16,;-8.3,2.39,;-6.96,3.16,;-6.96,4.7,;-8.3,5.47,;-5.63,2.39,;-4.29,3.16,;-2.96,2.39,;-2.96,.85,;-1.63,.08,;-.29,.85,;1.17,.37,;2.08,1.62,;3.62,1.62,;4.39,2.95,;3.62,4.29,;5.93,2.95,;6.83,4.2,;8.3,3.72,;8.3,2.18,;6.83,1.71,;9.63,1.41,;9.63,-.13,;10.96,2.18,;1.17,2.87,;-.29,2.39,;-1.63,3.16,;1.57,-1.11,;3.06,-1.51,;3.46,-3,;2.37,-4.09,;.88,-3.69,;-.21,-4.78,;-1.7,-4.38,;-2.1,-2.89,;-2.79,-5.47,;-4.27,-5.07,;.48,-2.2,)| Show InChI InChI=1S/C29H29F2N5O3S/c1-2-26(38)33-19-4-3-5-20(15-19)36-23-11-6-17(16-32-18-7-9-21(37)10-8-18)14-22(23)34-29(36)35-28(39)25-13-12-24(40-25)27(30)31/h2-6,11-15,18,21,27,32,37H,1,7-10,16H2,(H,33,38)(H,34,35,39)/t18-,21-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434526 (US10562893, Compound 28) Show SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3ccnn3C)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C |r| Show InChI InChI=1S/C28H33N7O2/c1-7-25(36)31-20-9-8-10-21(16-20)35-23-12-11-19(17-29-18(2)28(3,4)5)15-22(23)32-27(35)33-26(37)24-13-14-30-34(24)6/h7-16,18,29H,1,17H2,2-6H3,(H,31,36)(H,32,33,37)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434517 (US10562893, Compound 9) Show SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3cccc(c3)C#N)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C |r| Show InChI InChI=1S/C31H32N6O2/c1-6-28(38)34-24-11-8-12-25(17-24)37-27-14-13-22(19-33-20(2)31(3,4)5)16-26(27)35-30(37)36-29(39)23-10-7-9-21(15-23)18-32/h6-17,20,33H,1,19H2,2-5H3,(H,34,38)(H,35,36,39)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434518 (US10562893, Compound 11) Show SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3ccc(cc3)C#N)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C |r| Show InChI InChI=1S/C31H32N6O2/c1-6-28(38)34-24-8-7-9-25(17-24)37-27-15-12-22(19-33-20(2)31(3,4)5)16-26(27)35-30(37)36-29(39)23-13-10-21(18-32)11-14-23/h6-17,20,33H,1,19H2,2-5H3,(H,34,38)(H,35,36,39)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434520 (US10562893, Compound 16) Show SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3ccncc3)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C |r| Show InChI InChI=1S/C29H32N6O2/c1-6-26(36)32-22-8-7-9-23(17-22)35-25-11-10-20(18-31-19(2)29(3,4)5)16-24(25)33-28(35)34-27(37)21-12-14-30-15-13-21/h6-17,19,31H,1,18H2,2-5H3,(H,32,36)(H,33,34,37)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434521 (US10562893, Compound 17) Show SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3cncs3)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C |r| Show InChI InChI=1S/C27H30N6O2S/c1-6-24(34)30-19-8-7-9-20(13-19)33-22-11-10-18(14-29-17(2)27(3,4)5)12-21(22)31-26(33)32-25(35)23-15-28-16-36-23/h6-13,15-17,29H,1,14H2,2-5H3,(H,30,34)(H,31,32,35)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434522 (US10562893, Compound 18) Show SMILES C[C@H](NCc1ccc2n([C@H]3CC[C@H](C3)NC(=O)C=C)c(NC(=O)c3ccc(s3)C(F)F)nc2c1)C(C)(C)C |r| Show InChI InChI=1S/C28H35F2N5O2S/c1-6-24(36)32-18-8-9-19(14-18)35-21-10-7-17(15-31-16(2)28(3,4)5)13-20(21)33-27(35)34-26(37)23-12-11-22(38-23)25(29)30/h6-7,10-13,16,18-19,25,31H,1,8-9,14-15H2,2-5H3,(H,32,36)(H,33,34,37)/t16-,18+,19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434524 (US10562893, Compound 25) Show SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3ccc(s3)-c3cnco3)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C |r| Show InChI InChI=1S/C31H32N6O3S/c1-6-28(38)34-21-8-7-9-22(15-21)37-24-11-10-20(16-33-19(2)31(3,4)5)14-23(24)35-30(37)36-29(39)27-13-12-26(41-27)25-17-32-18-40-25/h6-15,17-19,33H,1,16H2,2-5H3,(H,34,38)(H,35,36,39)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	<10	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434529 (US10562893, Compound 42) Show SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3cnco3)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C |r| Show InChI InChI=1S/C27H30N6O3/c1-6-24(34)30-19-8-7-9-20(13-19)33-22-11-10-18(14-29-17(2)27(3,4)5)12-21(22)31-26(33)32-25(35)23-15-28-16-36-23/h6-13,15-17,29H,1,14H2,2-5H3,(H,30,34)(H,31,32,35)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434519 (US10562893, Compound 12) Show SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3nccs3)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C |r| Show InChI InChI=1S/C27H30N6O2S/c1-6-23(34)30-19-8-7-9-20(15-19)33-22-11-10-18(16-29-17(2)27(3,4)5)14-21(22)31-26(33)32-24(35)25-28-12-13-36-25/h6-15,17,29H,1,16H2,2-5H3,(H,30,34)(H,31,32,35)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434523 (US10562893, Compound 19) Show SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3cccnc3)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C |r| Show InChI InChI=1S/C29H32N6O2/c1-6-26(36)32-22-10-7-11-23(16-22)35-25-13-12-20(17-31-19(2)29(3,4)5)15-24(25)33-28(35)34-27(37)21-9-8-14-30-18-21/h6-16,18-19,31H,1,17H2,2-5H3,(H,32,36)(H,33,34,37)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434532 (US10562893, Compound 62) Show SMILES C[C@H](NCc1ccc2n([C@@H]3CC[C@@H](C3)NC(=O)C=C)c(NC(=O)c3ccc(s3)C(F)F)nc2c1)C(C)(C)C |r| Show InChI InChI=1S/C28H35F2N5O2S/c1-6-24(36)32-18-8-9-19(14-18)35-21-10-7-17(15-31-16(2)28(3,4)5)13-20(21)33-27(35)34-26(37)23-12-11-22(38-23)25(29)30/h6-7,10-13,16,18-19,25,31H,1,8-9,14-15H2,2-5H3,(H,32,36)(H,33,34,37)/t16-,18-,19+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434516 (US10562893, Compound 3) Show SMILES C[C@H](NCc1ccc2n([C@@H]3CC[C@@H](CC3)NC(=O)C=C)c(NC(=O)c3ccc(s3)C(F)F)nc2c1)C(C)(C)C |r,wU:9.8,12.15,wD:1.0,(-7.63,6.43,;-7.63,4.89,;-6.3,4.12,;-4.96,4.89,;-3.63,4.12,;-3.63,2.58,;-2.29,1.81,;-.96,2.58,;.5,2.1,;.9,.61,;-.19,-.48,;.21,-1.96,;1.7,-2.36,;2.79,-1.27,;2.39,.21,;2.1,-3.85,;1.01,-4.94,;1.41,-6.43,;-.48,-4.54,;-1.57,-5.63,;1.41,3.35,;2.95,3.35,;3.72,4.68,;2.95,6.01,;5.26,4.68,;6.16,5.93,;7.63,5.45,;7.63,3.91,;6.16,3.43,;8.96,3.14,;10.3,3.91,;8.96,1.6,;.5,4.59,;-.96,4.12,;-2.29,4.89,;-8.96,4.12,;-10.3,4.89,;-8.96,2.58,;-10.3,3.35,)| Show InChI InChI=1S/C29H37F2N5O2S/c1-6-25(37)33-19-8-10-20(11-9-19)36-22-12-7-18(16-32-17(2)29(3,4)5)15-21(22)34-28(36)35-27(38)24-14-13-23(39-24)26(30)31/h6-7,12-15,17,19-20,26,32H,1,8-11,16H2,2-5H3,(H,33,37)(H,34,35,38)/t17-,19-,20+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434535 (US10562893, Compound 81) Show SMILES C[C@H](NCc1ccc2n([C@H]3CCC[C@H](C3)NC(=O)C=C)c(NC(=O)c3ccc(s3)C(F)F)nc2c1)C(C)(C)C |r| Show InChI InChI=1S/C29H37F2N5O2S/c1-6-25(37)33-19-8-7-9-20(15-19)36-22-11-10-18(16-32-17(2)29(3,4)5)14-21(22)34-28(36)35-27(38)24-13-12-23(39-24)26(30)31/h6,10-14,17,19-20,26,32H,1,7-9,15-16H2,2-5H3,(H,33,37)(H,34,35,38)/t17-,19+,20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434514 (US10562893, Compound 1) Show SMILES C[C@H](NCc1ccc2n([C@@H]3C[C@@H](C3)NC(=O)C=C)c(NC(=O)c3ccc(s3)C(F)F)nc2c1)C(C)(C)C |r,wU:9.8,11.13,wD:1.0,(-7.63,5.65,;-7.63,4.11,;-6.3,3.34,;-4.96,4.11,;-3.63,3.34,;-3.63,1.8,;-2.29,1.03,;-.96,1.8,;.5,1.32,;.9,-.17,;.13,-1.5,;1.47,-2.27,;2.24,-.94,;1.86,-3.76,;3.35,-4.16,;3.75,-5.65,;4.44,-3.07,;5.93,-3.47,;1.41,2.57,;2.95,2.57,;3.72,3.9,;2.95,5.23,;5.26,3.9,;6.16,5.14,;7.63,4.67,;7.63,3.13,;6.16,2.65,;8.96,2.36,;10.3,3.13,;8.96,.82,;.5,3.81,;-.96,3.34,;-2.29,4.11,;-8.96,3.34,;-10.3,4.11,;-8.96,1.8,;-10.3,2.57,)| Show InChI InChI=1S/C27H33F2N5O2S/c1-6-23(35)31-17-12-18(13-17)34-20-8-7-16(14-30-15(2)27(3,4)5)11-19(20)32-26(34)33-25(36)22-10-9-21(37-22)24(28)29/h6-11,15,17-18,24,30H,1,12-14H2,2-5H3,(H,31,35)(H,32,33,36)/t15-,17-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	55	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair
Tyrosine-protein kinase TXK (Homo sapiens (Human))	BDBM434525 (US10562893, Compound 27) Show SMILES C[C@H](NCc1ccc2n(c(NC(=O)c3ccccn3)nc2c1)-c1cccc(NC(=O)C=C)c1)C(C)(C)C |r| Show InChI InChI=1S/C29H32N6O2/c1-6-26(36)32-21-10-9-11-22(17-21)35-25-14-13-20(18-31-19(2)29(3,4)5)16-24(25)33-28(35)34-27(37)23-12-7-8-15-30-23/h6-17,19,31H,1,18H2,2-5H3,(H,32,36)(H,33,34,37)/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>100	n/a	n/a	n/a	n/a
GB005, INC. US Patent					Assay Description RLK/TXK: The in vitro kinase assays were performed at Nanosyn utilizing micro-fluidic detection technology. The test compounds were serially pre-dilu...				US Patent US10562893 (2020) BindingDB Entry DOI: 10.7270/Q2571FC8
					More data for this Ligand-Target Pair