Compile Data Set for Download or QSAR

Found 13 hits of ki for UniProtKB: P31749   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase [1-123] (Homo sapiens (Human))	BDBM223480 (US9320734, PtdIns(3,4,5)trisphosphate) Show SMILES CCCCCCCCCCCCCCCC(=O)OCC(COP([O-])(=O)OC1[C@H](O)[C@H](OP([O-])([O-])=O)C(OP([O-])([O-])=O)[C@H](OP([O-])([O-])=O)[C@H]1O)OC(=O)CCCCCCCCCCCCCCC Show InChI InChI=1S/C41H82O22P4/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(42)57-31-33(59-35(43)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)32-58-67(55,56)63-38-36(44)39(60-64(46,47)48)41(62-66(52,53)54)40(37(38)45)61-65(49,50)51/h33,36-41,44-45H,3-32H2,1-2H3,(H,55,56)(H2,46,47,48)(H2,49,50,51)(H2,52,53,54)/p-7/t33?,36-,37-,38?,39-,40+,41?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem	US Patent	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona US Patent					Assay Description SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...				US Patent US9320734 (2016) BindingDB Entry DOI: 10.7270/Q2QF8RRM
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [1-123] (Homo sapiens (Human))	BDBM50304369 (4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonam...) Show SMILES CCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1 Show InChI InChI=1S/C20H31N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-15-19(16-14-18)27(24,25)23-20-22-21-17-26-20/h13-17H,2-12H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	US Patent	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona US Patent					Assay Description SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...				US Patent US9320734 (2016) BindingDB Entry DOI: 10.7270/Q2QF8RRM
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [1-123] (Homo sapiens (Human))	BDBM50304369 (4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonam...) Show SMILES CCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1 Show InChI InChI=1S/C20H31N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-15-19(16-14-18)27(24,25)23-20-22-21-17-26-20/h13-17H,2-12H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	US Patent	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona US Patent					Assay Description SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...				US Patent US9320734 (2016) BindingDB Entry DOI: 10.7270/Q2QF8RRM
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [1-123] (Homo sapiens (Human))	BDBM50338949 (4-Tetradecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfo...) Show SMILES CCCCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1 Show InChI InChI=1S/C22H35N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-20-15-17-21(18-16-20)29(26,27)25-22-24-23-19-28-22/h15-19H,2-14H2,1H3,(H,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona US Patent					Assay Description SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...				US Patent US9320734 (2016) BindingDB Entry DOI: 10.7270/Q2QF8RRM
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [1-123] (Homo sapiens (Human))	BDBM50338950 (4-Hexadecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfon...) Show SMILES CCCCCCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1 Show InChI InChI=1S/C24H39N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-22-17-19-23(20-18-22)31(28,29)27-24-26-25-21-30-24/h17-21H,2-16H2,1H3,(H,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona US Patent					Assay Description SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...				US Patent US9320734 (2016) BindingDB Entry DOI: 10.7270/Q2QF8RRM
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [1-123] (Homo sapiens (Human))	BDBM50338948 (4-Octyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamid...) Show SMILES CCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1 Show InChI InChI=1S/C16H23N3O2S2/c1-2-3-4-5-6-7-8-14-9-11-15(12-10-14)23(20,21)19-16-18-17-13-22-16/h9-13H,2-8H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona US Patent					Assay Description SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...				US Patent US9320734 (2016) BindingDB Entry DOI: 10.7270/Q2QF8RRM
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [1-123] (Homo sapiens (Human))	BDBM50338951 (4-Octadecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfon...) Show SMILES CCCCCCCCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1 Show InChI InChI=1S/C26H43N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24-19-21-25(22-20-24)33(30,31)29-26-28-27-23-32-26/h19-23H,2-18H2,1H3,(H,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	1.14E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona US Patent					Assay Description SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...				US Patent US9320734 (2016) BindingDB Entry DOI: 10.7270/Q2QF8RRM
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [1-123] (Homo sapiens (Human))	BDBM50304368 (CHEMBL595582 | N-(4-(N-1,3,4-thiadiazol-2-ylsulfam...) Show SMILES CCCCCCCCCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nncs1 Show InChI InChI=1S/C18H26N4O3S2/c1-2-3-4-5-6-7-8-9-17(23)20-15-10-12-16(13-11-15)27(24,25)22-18-21-19-14-26-18/h10-14H,2-9H2,1H3,(H,20,23)(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	2.18E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona US Patent					Assay Description SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...				US Patent US9320734 (2016) BindingDB Entry DOI: 10.7270/Q2QF8RRM
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [1-123] (Homo sapiens (Human))	BDBM50338947 (4-Hexyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamid...) Show SMILES CCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1 Show InChI InChI=1S/C14H19N3O2S2/c1-2-3-4-5-6-12-7-9-13(10-8-12)21(18,19)17-14-16-15-11-20-14/h7-11H,2-6H2,1H3,(H,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona US Patent					Assay Description SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...				US Patent US9320734 (2016) BindingDB Entry DOI: 10.7270/Q2QF8RRM
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [1-123] (Homo sapiens (Human))	BDBM50304371 (CHEMBL611216 | N-(4-(N-1,3,4-thiadiazol-2-ylsulfam...) Show SMILES COCCOCCOCC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nncs1 Show InChI InChI=1S/C15H20N4O6S2/c1-23-6-7-24-8-9-25-10-14(20)17-12-2-4-13(5-3-12)27(21,22)19-15-18-16-11-26-15/h2-5,11H,6-10H2,1H3,(H,17,20)(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona US Patent					Assay Description SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...				US Patent US9320734 (2016) BindingDB Entry DOI: 10.7270/Q2QF8RRM
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [1-123] (Homo sapiens (Human))	BDBM50304370 (CHEMBL593946 | N-(4-(N-1,3,4-thiadiazol-2-ylsulfam...) Show SMILES CC(=O)Nc1ccc(cc1)S(=O)(=O)Nc1nncs1 Show InChI InChI=1S/C10H10N4O3S2/c1-7(15)12-8-2-4-9(5-3-8)19(16,17)14-10-13-11-6-18-10/h2-6H,1H3,(H,12,15)(H,13,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona US Patent					Assay Description SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...				US Patent US9320734 (2016) BindingDB Entry DOI: 10.7270/Q2QF8RRM
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [1-123] (Homo sapiens (Human))	BDBM50034417 (4-Amino-N-[1,3,4]thiadiazol-2-yl-benzenesulfonamid...) Show SMILES Nc1ccc(cc1)S(=O)(=O)Nc1nncs1 Show InChI InChI=1S/C8H8N4O2S2/c9-6-1-3-7(4-2-6)16(13,14)12-8-11-10-5-15-8/h1-5H,9H2,(H,11,12)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	US Patent	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona US Patent					Assay Description SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...				US Patent US9320734 (2016) BindingDB Entry DOI: 10.7270/Q2QF8RRM
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [1-123] (Homo sapiens (Human))	BDBM50338946 (4-Butyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamid...) Show SMILES CCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1 Show InChI InChI=1S/C12H15N3O2S2/c1-2-3-4-10-5-7-11(8-6-10)19(16,17)15-12-14-13-9-18-12/h5-9H,2-4H2,1H3,(H,14,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	US Patent	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Board of Regents, The University of Texas System; Arizona Board of Regents on behalf of the University of Arizona US Patent					Assay Description SPR interaction analyses were performed with a Biacore 2000, using Biacore 2000 Control Software v3.2 and BIAevaluation v4.1 analysis software (Biaco...				US Patent US9320734 (2016) BindingDB Entry DOI: 10.7270/Q2QF8RRM
					More data for this Ligand-Target Pair