Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-secretase 1 (Homo sapiens (Human)) | BDBM136550 (US8865701, 31 | US9505739, 31) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 24 | n/a | n/a | n/a | n/a | 6.5 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate... | US Patent US8865701 (2014) BindingDB Entry DOI: 10.7270/Q2KP80V1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM136548 (US8865701, 21 | US9505739, 21) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 71 | n/a | n/a | n/a | n/a | 6.5 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate... | US Patent US8865701 (2014) BindingDB Entry DOI: 10.7270/Q2KP80V1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM136553 (US8865701, 77 | US9505739, 77) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 200 | n/a | n/a | n/a | n/a | 6.5 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate... | US Patent US8865701 (2014) BindingDB Entry DOI: 10.7270/Q2KP80V1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM136554 (US8865701, 100) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 450 | n/a | n/a | n/a | n/a | 6.5 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate... | US Patent US8865701 (2014) BindingDB Entry DOI: 10.7270/Q2KP80V1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM136547 (US8865701, 19 | US9505739, 19) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 920 | n/a | n/a | n/a | n/a | 6.5 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate... | US Patent US8865701 (2014) BindingDB Entry DOI: 10.7270/Q2KP80V1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM136544 (US8865701, 3 | US9505739, 3) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.19E+3 | n/a | n/a | n/a | n/a | 6.5 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate... | US Patent US8865701 (2014) BindingDB Entry DOI: 10.7270/Q2KP80V1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM136551 (US8865701, 38 | US9505739, 38) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | 6.5 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate... | US Patent US8865701 (2014) BindingDB Entry DOI: 10.7270/Q2KP80V1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM136549 (US8865701, 30 | US9505739, 30) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | 6.5 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate... | US Patent US8865701 (2014) BindingDB Entry DOI: 10.7270/Q2KP80V1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM136552 (US8865701, 44 | US9505739, 44) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | 6.5 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate... | US Patent US8865701 (2014) BindingDB Entry DOI: 10.7270/Q2KP80V1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM136546 (US8865701, 10) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | 6.5 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate... | US Patent US8865701 (2014) BindingDB Entry DOI: 10.7270/Q2KP80V1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 1 (Homo sapiens (Human)) | BDBM136545 (US8865701, 7 | US9505739, 7) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | 6.5 | n/a |
Merck Sharp & Dohme Corp. US Patent | Assay Description A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate... | US Patent US8865701 (2014) BindingDB Entry DOI: 10.7270/Q2KP80V1 | |||||||||||
More data for this Ligand-Target Pair |