Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epidermal growth factor receptor [1-973] (Homo sapiens (Human)) | BDBM152773 (4-(3-Morpholinopropoxy)-N-(3-chloro-4-fluorophenyl...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 10.4 | n/a | n/a | n/a | n/a | n/a | 25 |
Anhui University of Chinese Medicine | Assay Description The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen... | Chem Biol Drug Des 85: 280-9 (2015) Article DOI: 10.1111/cbdd.12383 BindingDB Entry DOI: 10.7270/Q2JD4VJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [1-973] (Homo sapiens (Human)) | BDBM5447 (CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB Article PubMed | n/a | n/a | 12.1 | n/a | n/a | n/a | n/a | n/a | 25 |
Anhui University of Chinese Medicine | Assay Description The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen... | Chem Biol Drug Des 85: 280-9 (2015) Article DOI: 10.1111/cbdd.12383 BindingDB Entry DOI: 10.7270/Q2JD4VJR | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Epidermal growth factor receptor [1-973] (Homo sapiens (Human)) | BDBM152779 (4-(3-(Piperidin-1-yl)propoxy)-N-(3-chloro-4-fluoro...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 15.4 | n/a | n/a | n/a | n/a | n/a | 25 |
Anhui University of Chinese Medicine | Assay Description The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen... | Chem Biol Drug Des 85: 280-9 (2015) Article DOI: 10.1111/cbdd.12383 BindingDB Entry DOI: 10.7270/Q2JD4VJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [1-973] (Homo sapiens (Human)) | BDBM152777 (4-(3-(Piperidin-1-yl)propoxy)-N-(m-tolyl)-2-hydrox...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 22.4 | n/a | n/a | n/a | n/a | n/a | 25 |
Anhui University of Chinese Medicine | Assay Description The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen... | Chem Biol Drug Des 85: 280-9 (2015) Article DOI: 10.1111/cbdd.12383 BindingDB Entry DOI: 10.7270/Q2JD4VJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [1-973] (Homo sapiens (Human)) | BDBM152780 (4-(3-(Piperidin-1-yl)propoxy)-N-(2-chloro-4-nitrop...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | 25 |
Anhui University of Chinese Medicine | Assay Description The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen... | Chem Biol Drug Des 85: 280-9 (2015) Article DOI: 10.1111/cbdd.12383 BindingDB Entry DOI: 10.7270/Q2JD4VJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [1-973] (Homo sapiens (Human)) | BDBM152772 (4-(3-Morpholinopropoxy)-N-(3-(trifluoromethyl)phen...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 34.6 | n/a | n/a | n/a | n/a | n/a | 25 |
Anhui University of Chinese Medicine | Assay Description The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen... | Chem Biol Drug Des 85: 280-9 (2015) Article DOI: 10.1111/cbdd.12383 BindingDB Entry DOI: 10.7270/Q2JD4VJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [1-973] (Homo sapiens (Human)) | BDBM152778 (4-(3-(Piperidin-1-yl)propoxy)-N-(3-(trifluoromethy...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 35.2 | n/a | n/a | n/a | n/a | n/a | 25 |
Anhui University of Chinese Medicine | Assay Description The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen... | Chem Biol Drug Des 85: 280-9 (2015) Article DOI: 10.1111/cbdd.12383 BindingDB Entry DOI: 10.7270/Q2JD4VJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [1-973] (Homo sapiens (Human)) | BDBM152775 (4-(3-(Piperidin-1-yl)propoxy)-N-(3-bromophenyl)-2-...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 45.7 | n/a | n/a | n/a | n/a | n/a | 25 |
Anhui University of Chinese Medicine | Assay Description The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen... | Chem Biol Drug Des 85: 280-9 (2015) Article DOI: 10.1111/cbdd.12383 BindingDB Entry DOI: 10.7270/Q2JD4VJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [1-973] (Homo sapiens (Human)) | BDBM152776 (4-(3-(Piperidin-1-yl)propoxy)-N-(3-chlorophenyl)-2...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 63.9 | n/a | n/a | n/a | n/a | n/a | 25 |
Anhui University of Chinese Medicine | Assay Description The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen... | Chem Biol Drug Des 85: 280-9 (2015) Article DOI: 10.1111/cbdd.12383 BindingDB Entry DOI: 10.7270/Q2JD4VJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [1-973] (Homo sapiens (Human)) | BDBM152774 (4-(3-Morpholinopropoxy)-N-(2-chloro-4-nitrophenyl)...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 84.8 | n/a | n/a | n/a | n/a | n/a | 25 |
Anhui University of Chinese Medicine | Assay Description The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen... | Chem Biol Drug Des 85: 280-9 (2015) Article DOI: 10.1111/cbdd.12383 BindingDB Entry DOI: 10.7270/Q2JD4VJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [1-973] (Homo sapiens (Human)) | BDBM152769 (4-(3-morpholinopropoxy)-N-(3-bromophenyl)-2-hydrox...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 85.8 | n/a | n/a | n/a | n/a | n/a | 25 |
Anhui University of Chinese Medicine | Assay Description The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen... | Chem Biol Drug Des 85: 280-9 (2015) Article DOI: 10.1111/cbdd.12383 BindingDB Entry DOI: 10.7270/Q2JD4VJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [1-973] (Homo sapiens (Human)) | BDBM152771 (4-(3-Morpholinopropoxy)-N-(m-tolyl)-2-hydroxybenza...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 142 | n/a | n/a | n/a | n/a | n/a | 25 |
Anhui University of Chinese Medicine | Assay Description The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen... | Chem Biol Drug Des 85: 280-9 (2015) Article DOI: 10.1111/cbdd.12383 BindingDB Entry DOI: 10.7270/Q2JD4VJR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Epidermal growth factor receptor [1-973] (Homo sapiens (Human)) | BDBM152770 (4-(3-Morpholinopropoxy)-N-(3-chlorophenyl)-2-hydro...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 196 | n/a | n/a | n/a | n/a | n/a | 25 |
Anhui University of Chinese Medicine | Assay Description The experiments were performed according to the instructions of the manufacturer. The EGFR TK activity was performed using Kinase-Glo Plus luminescen... | Chem Biol Drug Des 85: 280-9 (2015) Article DOI: 10.1111/cbdd.12383 BindingDB Entry DOI: 10.7270/Q2JD4VJR | |||||||||||
More data for this Ligand-Target Pair |