Found 129 hits Enz. Inhib. hit(s) with all data for entry = 7998 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229525
(US9334279, 1001)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1cnccn1 |r,c:42| Show InChI InChI=1S/C47H58F3N7O9S/c1-27(2)64-32-14-12-30(13-15-32)35-21-33(22-36(53-35)37-25-51-18-19-52-37)65-34-23-38-40(58)55-46(42(60)56-67(62,63)45(7)16-17-45)24-31(46)11-9-8-10-28(3)20-29(4)39(41(59)57(38)26-34)54-43(61)66-44(5,6)47(48,49)50/h9,11-15,18-19,21-22,25,27-29,31,34,38-39H,8,10,16-17,20,23-24,26H2,1-7H3,(H,54,61)(H,55,58)(H,56,60)/b11-9-/t28-,29-,31?,34-,38+,39+,46-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229525
(US9334279, 1001)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1cnccn1 |r,c:42| Show InChI InChI=1S/C47H58F3N7O9S/c1-27(2)64-32-14-12-30(13-15-32)35-21-33(22-36(53-35)37-25-51-18-19-52-37)65-34-23-38-40(58)55-46(42(60)56-67(62,63)45(7)16-17-45)24-31(46)11-9-8-10-28(3)20-29(4)39(41(59)57(38)26-34)54-43(61)66-44(5,6)47(48,49)50/h9,11-15,18-19,21-22,25,27-29,31,34,38-39H,8,10,16-17,20,23-24,26H2,1-7H3,(H,54,61)(H,55,58)(H,56,60)/b11-9-/t28-,29-,31?,34-,38+,39+,46-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 0.75 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229526
(US9334279, 1002)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1cnccn1 |r,c:42| Show InChI InChI=1S/C47H58F3N7O9S/c1-27(2)64-32-14-12-30(13-15-32)35-21-33(22-36(53-35)37-25-51-18-19-52-37)65-34-23-38-40(58)55-46(42(60)56-67(62,63)45(7)16-17-45)24-31(46)11-9-8-10-28(3)20-29(4)39(41(59)57(38)26-34)54-43(61)66-44(5,6)47(48,49)50/h9,11-15,18-19,21-22,25,27-29,31,34,38-39H,8,10,16-17,20,23-24,26H2,1-7H3,(H,54,61)(H,55,58)(H,56,60)/b11-9-/t28-,29+,31?,34+,38-,39-,46+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 59 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229526
(US9334279, 1002)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1cnccn1 |r,c:42| Show InChI InChI=1S/C47H58F3N7O9S/c1-27(2)64-32-14-12-30(13-15-32)35-21-33(22-36(53-35)37-25-51-18-19-52-37)65-34-23-38-40(58)55-46(42(60)56-67(62,63)45(7)16-17-45)24-31(46)11-9-8-10-28(3)20-29(4)39(41(59)57(38)26-34)54-43(61)66-44(5,6)47(48,49)50/h9,11-15,18-19,21-22,25,27-29,31,34,38-39H,8,10,16-17,20,23-24,26H2,1-7H3,(H,54,61)(H,55,58)(H,56,60)/b11-9-/t28-,29+,31?,34+,38-,39-,46+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 11.6 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229527
(US9334279, 1003)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1cncs1 |r,c:42| Show InChI InChI=1S/C46H57F3N6O9S2/c1-26(2)62-31-14-12-29(13-15-31)34-19-32(20-35(51-34)37-23-50-25-65-37)63-33-21-36-39(56)53-45(41(58)54-66(60,61)44(7)16-17-44)22-30(45)11-9-8-10-27(3)18-28(4)38(40(57)55(36)24-33)52-42(59)64-43(5,6)46(47,48)49/h9,11-15,19-20,23,25-28,30,33,36,38H,8,10,16-18,21-22,24H2,1-7H3,(H,52,59)(H,53,56)(H,54,58)/b11-9-/t27-,28-,30?,33-,36+,38+,45-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229527
(US9334279, 1003)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1cncs1 |r,c:42| Show InChI InChI=1S/C46H57F3N6O9S2/c1-26(2)62-31-14-12-29(13-15-31)34-19-32(20-35(51-34)37-23-50-25-65-37)63-33-21-36-39(56)53-45(41(58)54-66(60,61)44(7)16-17-44)22-30(45)11-9-8-10-27(3)18-28(4)38(40(57)55(36)24-33)52-42(59)64-43(5,6)46(47,48)49/h9,11-15,19-20,23,25-28,30,33,36,38H,8,10,16-18,21-22,24H2,1-7H3,(H,52,59)(H,53,56)(H,54,58)/b11-9-/t27-,28-,30?,33-,36+,38+,45-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229528
(US9334279, 1004)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1cncs1 |r,c:42| Show InChI InChI=1S/C46H57F3N6O9S2/c1-26(2)62-31-14-12-29(13-15-31)34-19-32(20-35(51-34)37-23-50-25-65-37)63-33-21-36-39(56)53-45(41(58)54-66(60,61)44(7)16-17-44)22-30(45)11-9-8-10-27(3)18-28(4)38(40(57)55(36)24-33)52-42(59)64-43(5,6)46(47,48)49/h9,11-15,19-20,23,25-28,30,33,36,38H,8,10,16-18,21-22,24H2,1-7H3,(H,52,59)(H,53,56)(H,54,58)/b11-9-/t27-,28+,30?,33+,36-,38-,45+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229529
(US9334279, 1005)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1cccnc1 |r,c:42| Show InChI InChI=1S/C48H59F3N6O9S/c1-28(2)64-34-16-14-31(15-17-34)37-22-35(23-38(53-37)32-12-10-20-52-26-32)65-36-24-39-41(58)55-47(43(60)56-67(62,63)46(7)18-19-46)25-33(47)13-9-8-11-29(3)21-30(4)40(42(59)57(39)27-36)54-44(61)66-45(5,6)48(49,50)51/h9-10,12-17,20,22-23,26,28-30,33,36,39-40H,8,11,18-19,21,24-25,27H2,1-7H3,(H,54,61)(H,55,58)(H,56,60)/b13-9-/t29-,30-,33?,36-,39+,40+,47-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 1.48 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229529
(US9334279, 1005)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1cccnc1 |r,c:42| Show InChI InChI=1S/C48H59F3N6O9S/c1-28(2)64-34-16-14-31(15-17-34)37-22-35(23-38(53-37)32-12-10-20-52-26-32)65-36-24-39-41(58)55-47(43(60)56-67(62,63)46(7)18-19-46)25-33(47)13-9-8-11-29(3)21-30(4)40(42(59)57(39)27-36)54-44(61)66-45(5,6)48(49,50)51/h9-10,12-17,20,22-23,26,28-30,33,36,39-40H,8,11,18-19,21,24-25,27H2,1-7H3,(H,54,61)(H,55,58)(H,56,60)/b13-9-/t29-,30-,33?,36-,39+,40+,47-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 1.71 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229530
(US9334279, 1006)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1cccnc1 |r,c:42| Show InChI InChI=1S/C48H59F3N6O9S/c1-28(2)64-34-16-14-31(15-17-34)37-22-35(23-38(53-37)32-12-10-20-52-26-32)65-36-24-39-41(58)55-47(43(60)56-67(62,63)46(7)18-19-46)25-33(47)13-9-8-11-29(3)21-30(4)40(42(59)57(39)27-36)54-44(61)66-45(5,6)48(49,50)51/h9-10,12-17,20,22-23,26,28-30,33,36,39-40H,8,11,18-19,21,24-25,27H2,1-7H3,(H,54,61)(H,55,58)(H,56,60)/b13-9-/t29-,30+,33?,36+,39-,40-,47+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229530
(US9334279, 1006)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1cccnc1 |r,c:42| Show InChI InChI=1S/C48H59F3N6O9S/c1-28(2)64-34-16-14-31(15-17-34)37-22-35(23-38(53-37)32-12-10-20-52-26-32)65-36-24-39-41(58)55-47(43(60)56-67(62,63)46(7)18-19-46)25-33(47)13-9-8-11-29(3)21-30(4)40(42(59)57(39)27-36)54-44(61)66-45(5,6)48(49,50)51/h9-10,12-17,20,22-23,26,28-30,33,36,39-40H,8,11,18-19,21,24-25,27H2,1-7H3,(H,54,61)(H,55,58)(H,56,60)/b13-9-/t29-,30+,33?,36+,39-,40-,47+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229531
(US9334279, 1007)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1nccs1 |r,c:42| Show InChI InChI=1S/C46H57F3N6O9S2/c1-26(2)62-31-14-12-29(13-15-31)34-21-32(22-35(51-34)39-50-18-19-65-39)63-33-23-36-38(56)53-45(41(58)54-66(60,61)44(7)16-17-44)24-30(45)11-9-8-10-27(3)20-28(4)37(40(57)55(36)25-33)52-42(59)64-43(5,6)46(47,48)49/h9,11-15,18-19,21-22,26-28,30,33,36-37H,8,10,16-17,20,23-25H2,1-7H3,(H,52,59)(H,53,56)(H,54,58)/b11-9-/t27-,28-,30?,33-,36+,37+,45-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229532
(US9334279, 1008)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1nccs1 |r,c:42| Show InChI InChI=1S/C46H57F3N6O9S2/c1-26(2)62-31-14-12-29(13-15-31)34-21-32(22-35(51-34)39-50-18-19-65-39)63-33-23-36-38(56)53-45(41(58)54-66(60,61)44(7)16-17-44)24-30(45)11-9-8-10-27(3)20-28(4)37(40(57)55(36)25-33)52-42(59)64-43(5,6)46(47,48)49/h9,11-15,18-19,21-22,26-28,30,33,36-37H,8,10,16-17,20,23-25H2,1-7H3,(H,52,59)(H,53,56)(H,54,58)/b11-9-/t27-,28+,30?,33+,36-,37-,45+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229532
(US9334279, 1008)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1nccs1 |r,c:42| Show InChI InChI=1S/C46H57F3N6O9S2/c1-26(2)62-31-14-12-29(13-15-31)34-21-32(22-35(51-34)39-50-18-19-65-39)63-33-23-36-38(56)53-45(41(58)54-66(60,61)44(7)16-17-44)24-30(45)11-9-8-10-27(3)20-28(4)37(40(57)55(36)25-33)52-42(59)64-43(5,6)46(47,48)49/h9,11-15,18-19,21-22,26-28,30,33,36-37H,8,10,16-17,20,23-25H2,1-7H3,(H,52,59)(H,53,56)(H,54,58)/b11-9-/t27-,28+,30?,33+,36-,37-,45+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229533
(US9334279, 1009)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1ccncc1 |r,c:42| Show InChI InChI=1S/C48H59F3N6O9S/c1-28(2)64-34-14-12-31(13-15-34)37-23-35(24-38(53-37)32-16-20-52-21-17-32)65-36-25-39-41(58)55-47(43(60)56-67(62,63)46(7)18-19-46)26-33(47)11-9-8-10-29(3)22-30(4)40(42(59)57(39)27-36)54-44(61)66-45(5,6)48(49,50)51/h9,11-17,20-21,23-24,28-30,33,36,39-40H,8,10,18-19,22,25-27H2,1-7H3,(H,54,61)(H,55,58)(H,56,60)/b11-9-/t29-,30-,33?,36-,39+,40+,47-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229533
(US9334279, 1009)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1ccncc1 |r,c:42| Show InChI InChI=1S/C48H59F3N6O9S/c1-28(2)64-34-14-12-31(13-15-34)37-23-35(24-38(53-37)32-16-20-52-21-17-32)65-36-25-39-41(58)55-47(43(60)56-67(62,63)46(7)18-19-46)26-33(47)11-9-8-10-29(3)22-30(4)40(42(59)57(39)27-36)54-44(61)66-45(5,6)48(49,50)51/h9,11-17,20-21,23-24,28-30,33,36,39-40H,8,10,18-19,22,25-27H2,1-7H3,(H,54,61)(H,55,58)(H,56,60)/b11-9-/t29-,30-,33?,36-,39+,40+,47-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229534
(US9334279, 1010)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1ccncc1 |r,c:42| Show InChI InChI=1S/C48H59F3N6O9S/c1-28(2)64-34-14-12-31(13-15-34)37-23-35(24-38(53-37)32-16-20-52-21-17-32)65-36-25-39-41(58)55-47(43(60)56-67(62,63)46(7)18-19-46)26-33(47)11-9-8-10-29(3)22-30(4)40(42(59)57(39)27-36)54-44(61)66-45(5,6)48(49,50)51/h9,11-17,20-21,23-24,28-30,33,36,39-40H,8,10,18-19,22,25-27H2,1-7H3,(H,54,61)(H,55,58)(H,56,60)/b11-9-/t29-,30+,33?,36+,39-,40-,47+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229535
(US9334279, 1011)Show SMILES COc1cccc(n1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1ccc(OC(C)C)cc1 |r,c:40| Show InChI InChI=1S/C49H61F3N6O10S/c1-28(2)66-33-18-16-31(17-19-33)37-23-34(24-38(53-37)36-14-11-15-40(54-36)65-8)67-35-25-39-42(59)56-48(44(61)57-69(63,64)47(7)20-21-47)26-32(48)13-10-9-12-29(3)22-30(4)41(43(60)58(39)27-35)55-45(62)68-46(5,6)49(50,51)52/h10-11,13-19,23-24,28-30,32,35,39,41H,9,12,20-22,25-27H2,1-8H3,(H,55,62)(H,56,59)(H,57,61)/b13-10-/t29-,30-,32?,35-,39+,41+,48-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229535
(US9334279, 1011)Show SMILES COc1cccc(n1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1ccc(OC(C)C)cc1 |r,c:40| Show InChI InChI=1S/C49H61F3N6O10S/c1-28(2)66-33-18-16-31(17-19-33)37-23-34(24-38(53-37)36-14-11-15-40(54-36)65-8)67-35-25-39-42(59)56-48(44(61)57-69(63,64)47(7)20-21-47)26-32(48)13-10-9-12-29(3)22-30(4)41(43(60)58(39)27-35)55-45(62)68-46(5,6)49(50,51)52/h10-11,13-19,23-24,28-30,32,35,39,41H,9,12,20-22,25-27H2,1-8H3,(H,55,62)(H,56,59)(H,57,61)/b13-10-/t29-,30-,32?,35-,39+,41+,48-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229536
(US9334279, 1012)Show SMILES COc1cccc(n1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1ccc(OC(C)C)cc1 |r,c:40| Show InChI InChI=1S/C49H61F3N6O10S/c1-28(2)66-33-18-16-31(17-19-33)37-23-34(24-38(53-37)36-14-11-15-40(54-36)65-8)67-35-25-39-42(59)56-48(44(61)57-69(63,64)47(7)20-21-47)26-32(48)13-10-9-12-29(3)22-30(4)41(43(60)58(39)27-35)55-45(62)68-46(5,6)49(50,51)52/h10-11,13-19,23-24,28-30,32,35,39,41H,9,12,20-22,25-27H2,1-8H3,(H,55,62)(H,56,59)(H,57,61)/b13-10-/t29-,30+,32?,35+,39-,41-,48+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229536
(US9334279, 1012)Show SMILES COc1cccc(n1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1ccc(OC(C)C)cc1 |r,c:40| Show InChI InChI=1S/C49H61F3N6O10S/c1-28(2)66-33-18-16-31(17-19-33)37-23-34(24-38(53-37)36-14-11-15-40(54-36)65-8)67-35-25-39-42(59)56-48(44(61)57-69(63,64)47(7)20-21-47)26-32(48)13-10-9-12-29(3)22-30(4)41(43(60)58(39)27-35)55-45(62)68-46(5,6)49(50,51)52/h10-11,13-19,23-24,28-30,32,35,39,41H,9,12,20-22,25-27H2,1-8H3,(H,55,62)(H,56,59)(H,57,61)/b13-10-/t29-,30+,32?,35+,39-,41-,48+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229537
(US9334279, 1013)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-n1cccn1 |r,c:42| Show InChI InChI=1S/C46H58F3N7O9S/c1-27(2)63-32-15-13-30(14-16-32)35-22-33(24-37(51-35)56-20-10-19-50-56)64-34-23-36-39(57)53-45(41(59)54-66(61,62)44(7)17-18-44)25-31(45)12-9-8-11-28(3)21-29(4)38(40(58)55(36)26-34)52-42(60)65-43(5,6)46(47,48)49/h9-10,12-16,19-20,22,24,27-29,31,34,36,38H,8,11,17-18,21,23,25-26H2,1-7H3,(H,52,60)(H,53,57)(H,54,59)/b12-9-/t28-,29-,31?,34-,36+,38+,45-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229538
(US9334279, 1014)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-n1cccn1 |r,c:42| Show InChI InChI=1S/C46H58F3N7O9S/c1-27(2)63-32-15-13-30(14-16-32)35-22-33(24-37(51-35)56-20-10-19-50-56)64-34-23-36-39(57)53-45(41(59)54-66(61,62)44(7)17-18-44)25-31(45)12-9-8-11-28(3)21-29(4)38(40(58)55(36)26-34)52-42(60)65-43(5,6)46(47,48)49/h9-10,12-16,19-20,22,24,27-29,31,34,36,38H,8,11,17-18,21,23,25-26H2,1-7H3,(H,52,60)(H,53,57)(H,54,59)/b12-9-/t28-,29+,31?,34+,36-,38-,45+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 197 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229538
(US9334279, 1014)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-n1cccn1 |r,c:42| Show InChI InChI=1S/C46H58F3N7O9S/c1-27(2)63-32-15-13-30(14-16-32)35-22-33(24-37(51-35)56-20-10-19-50-56)64-34-23-36-39(57)53-45(41(59)54-66(61,62)44(7)17-18-44)25-31(45)12-9-8-11-28(3)21-29(4)38(40(58)55(36)26-34)52-42(60)65-43(5,6)46(47,48)49/h9-10,12-16,19-20,22,24,27-29,31,34,36,38H,8,11,17-18,21,23,25-26H2,1-7H3,(H,52,60)(H,53,57)(H,54,59)/b12-9-/t28-,29+,31?,34+,36-,38-,45+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229539
(US9334279, 1015)Show SMILES C[C@@H]1CC\C=C/[C@@H]2C[C@]2(NC(=O)[C@@H]2C[C@H](CN2C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C1)Oc1cc(C)nc(c1)-c1cncs1)C(=O)NS(=O)(=O)C1(C)CC1 |r,c:4| Show InChI InChI=1S/C38H49F3N6O8S2/c1-21-9-7-8-10-24-17-37(24,33(50)46-57(52,53)36(6)11-12-36)45-31(48)28-16-26(54-25-14-23(3)43-27(15-25)29-18-42-20-56-29)19-47(28)32(49)30(22(2)13-21)44-34(51)55-35(4,5)38(39,40)41/h8,10,14-15,18,20-22,24,26,28,30H,7,9,11-13,16-17,19H2,1-6H3,(H,44,51)(H,45,48)(H,46,50)/b10-8-/t21-,22-,24?,26-,28+,30+,37-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229539
(US9334279, 1015)Show SMILES C[C@@H]1CC\C=C/[C@@H]2C[C@]2(NC(=O)[C@@H]2C[C@H](CN2C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C1)Oc1cc(C)nc(c1)-c1cncs1)C(=O)NS(=O)(=O)C1(C)CC1 |r,c:4| Show InChI InChI=1S/C38H49F3N6O8S2/c1-21-9-7-8-10-24-17-37(24,33(50)46-57(52,53)36(6)11-12-36)45-31(48)28-16-26(54-25-14-23(3)43-27(15-25)29-18-42-20-56-29)19-47(28)32(49)30(22(2)13-21)44-34(51)55-35(4,5)38(39,40)41/h8,10,14-15,18,20-22,24,26,28,30H,7,9,11-13,16-17,19H2,1-6H3,(H,44,51)(H,45,48)(H,46,50)/b10-8-/t21-,22-,24?,26-,28+,30+,37-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229540
(US9334279, 1016)Show SMILES C[C@H]1CC\C=C/[C@@H]2C[C@]2(NC(=O)[C@@H]2C[C@H](CN2C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C1)Oc1cc(C)nc(c1)-c1cncs1)C(=O)NS(=O)(=O)C1(C)CC1 |r,c:4| Show InChI InChI=1S/C38H49F3N6O8S2/c1-21-9-7-8-10-24-17-37(24,33(50)46-57(52,53)36(6)11-12-36)45-31(48)28-16-26(54-25-14-23(3)43-27(15-25)29-18-42-20-56-29)19-47(28)32(49)30(22(2)13-21)44-34(51)55-35(4,5)38(39,40)41/h8,10,14-15,18,20-22,24,26,28,30H,7,9,11-13,16-17,19H2,1-6H3,(H,44,51)(H,45,48)(H,46,50)/b10-8-/t21-,22+,24?,26+,28-,30-,37+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 197 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229541
(US9334279, 1017)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC2(CCCOC2)C(F)(F)F)[C@H](C)C[C@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1cncs1 |r,c:46| Show InChI InChI=1S/C48H59F3N6O10S2/c1-28(2)65-33-13-11-31(12-14-33)36-20-34(21-37(53-36)39-24-52-27-68-39)66-35-22-38-41(58)55-47(43(60)56-69(62,63)45(5)16-17-45)23-32(47)10-7-6-9-29(3)19-30(4)40(42(59)57(38)25-35)54-44(61)67-46(48(49,50)51)15-8-18-64-26-46/h7,10-14,20-21,24,27-30,32,35,38,40H,6,8-9,15-19,22-23,25-26H2,1-5H3,(H,54,61)(H,55,58)(H,56,60)/b10-7-/t29-,30-,32?,35-,38+,40+,46?,47-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 0.950 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229541
(US9334279, 1017)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC2(CCCOC2)C(F)(F)F)[C@H](C)C[C@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1cncs1 |r,c:46| Show InChI InChI=1S/C48H59F3N6O10S2/c1-28(2)65-33-13-11-31(12-14-33)36-20-34(21-37(53-36)39-24-52-27-68-39)66-35-22-38-41(58)55-47(43(60)56-69(62,63)45(5)16-17-45)23-32(47)10-7-6-9-29(3)19-30(4)40(42(59)57(38)25-35)54-44(61)67-46(48(49,50)51)15-8-18-64-26-46/h7,10-14,20-21,24,27-30,32,35,38,40H,6,8-9,15-19,22-23,25-26H2,1-5H3,(H,54,61)(H,55,58)(H,56,60)/b10-7-/t29-,30-,32?,35-,38+,40+,46?,47-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 0.820 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229542
(US9334279, 1018)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC2(CCCOC2)C(F)(F)F)[C@H](C)C[C@@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1cncs1 |r,c:46| Show InChI InChI=1S/C48H59F3N6O10S2/c1-28(2)65-33-13-11-31(12-14-33)36-20-34(21-37(53-36)39-24-52-27-68-39)66-35-22-38-41(58)55-47(43(60)56-69(62,63)45(5)16-17-45)23-32(47)10-7-6-9-29(3)19-30(4)40(42(59)57(38)25-35)54-44(61)67-46(48(49,50)51)15-8-18-64-26-46/h7,10-14,20-21,24,27-30,32,35,38,40H,6,8-9,15-19,22-23,25-26H2,1-5H3,(H,54,61)(H,55,58)(H,56,60)/b10-7-/t29-,30+,32?,35+,38-,40-,46?,47+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229542
(US9334279, 1018)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC2(CCCOC2)C(F)(F)F)[C@H](C)C[C@@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1cncs1 |r,c:46| Show InChI InChI=1S/C48H59F3N6O10S2/c1-28(2)65-33-13-11-31(12-14-33)36-20-34(21-37(53-36)39-24-52-27-68-39)66-35-22-38-41(58)55-47(43(60)56-69(62,63)45(5)16-17-45)23-32(47)10-7-6-9-29(3)19-30(4)40(42(59)57(38)25-35)54-44(61)67-46(48(49,50)51)15-8-18-64-26-46/h7,10-14,20-21,24,27-30,32,35,38,40H,6,8-9,15-19,22-23,25-26H2,1-5H3,(H,54,61)(H,55,58)(H,56,60)/b10-7-/t29-,30+,32?,35+,38-,40-,46?,47+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229543
(US9334279, 1019)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1ncccn1 |r,c:42| Show InChI InChI=1S/C47H58F3N7O9S/c1-27(2)64-32-15-13-30(14-16-32)35-22-33(23-36(53-35)39-51-19-10-20-52-39)65-34-24-37-40(58)55-46(42(60)56-67(62,63)45(7)17-18-45)25-31(46)12-9-8-11-28(3)21-29(4)38(41(59)57(37)26-34)54-43(61)66-44(5,6)47(48,49)50/h9-10,12-16,19-20,22-23,27-29,31,34,37-38H,8,11,17-18,21,24-26H2,1-7H3,(H,54,61)(H,55,58)(H,56,60)/b12-9-/t28-,29-,31?,34-,37+,38+,46-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229543
(US9334279, 1019)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1ncccn1 |r,c:42| Show InChI InChI=1S/C47H58F3N7O9S/c1-27(2)64-32-15-13-30(14-16-32)35-22-33(23-36(53-35)39-51-19-10-20-52-39)65-34-24-37-40(58)55-46(42(60)56-67(62,63)45(7)17-18-45)25-31(46)12-9-8-11-28(3)21-29(4)38(41(59)57(37)26-34)54-43(61)66-44(5,6)47(48,49)50/h9-10,12-16,19-20,22-23,27-29,31,34,37-38H,8,11,17-18,21,24-26H2,1-7H3,(H,54,61)(H,55,58)(H,56,60)/b12-9-/t28-,29-,31?,34-,37+,38+,46-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229544
(US9334279, 1020)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1ncccn1 |r,c:42| Show InChI InChI=1S/C47H58F3N7O9S/c1-27(2)64-32-15-13-30(14-16-32)35-22-33(23-36(53-35)39-51-19-10-20-52-39)65-34-24-37-40(58)55-46(42(60)56-67(62,63)45(7)17-18-45)25-31(46)12-9-8-11-28(3)21-29(4)38(41(59)57(37)26-34)54-43(61)66-44(5,6)47(48,49)50/h9-10,12-16,19-20,22-23,27-29,31,34,37-38H,8,11,17-18,21,24-26H2,1-7H3,(H,54,61)(H,55,58)(H,56,60)/b12-9-/t28-,29+,31?,34+,37-,38-,46+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229544
(US9334279, 1020)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1ncccn1 |r,c:42| Show InChI InChI=1S/C47H58F3N7O9S/c1-27(2)64-32-15-13-30(14-16-32)35-22-33(23-36(53-35)39-51-19-10-20-52-39)65-34-24-37-40(58)55-46(42(60)56-67(62,63)45(7)17-18-45)25-31(46)12-9-8-11-28(3)21-29(4)38(41(59)57(37)26-34)54-43(61)66-44(5,6)47(48,49)50/h9-10,12-16,19-20,22-23,27-29,31,34,37-38H,8,11,17-18,21,24-26H2,1-7H3,(H,54,61)(H,55,58)(H,56,60)/b12-9-/t28-,29+,31?,34+,37-,38-,46+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229545
(US9334279, 1021)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1ccccn1 |r,c:42| Show InChI InChI=1S/C48H59F3N6O9S/c1-28(2)64-33-17-15-31(16-18-33)37-23-34(24-38(53-37)36-14-10-11-21-52-36)65-35-25-39-41(58)55-47(43(60)56-67(62,63)46(7)19-20-46)26-32(47)13-9-8-12-29(3)22-30(4)40(42(59)57(39)27-35)54-44(61)66-45(5,6)48(49,50)51/h9-11,13-18,21,23-24,28-30,32,35,39-40H,8,12,19-20,22,25-27H2,1-7H3,(H,54,61)(H,55,58)(H,56,60)/b13-9-/t29-,30-,32?,35-,39+,40+,47-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229545
(US9334279, 1021)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1ccccn1 |r,c:42| Show InChI InChI=1S/C48H59F3N6O9S/c1-28(2)64-33-17-15-31(16-18-33)37-23-34(24-38(53-37)36-14-10-11-21-52-36)65-35-25-39-41(58)55-47(43(60)56-67(62,63)46(7)19-20-46)26-32(47)13-9-8-12-29(3)22-30(4)40(42(59)57(39)27-35)54-44(61)66-45(5,6)48(49,50)51/h9-11,13-18,21,23-24,28-30,32,35,39-40H,8,12,19-20,22,25-27H2,1-7H3,(H,54,61)(H,55,58)(H,56,60)/b13-9-/t29-,30-,32?,35-,39+,40+,47-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 0.75 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229546
(US9334279, 1022)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1ccccn1 |r,c:42| Show InChI InChI=1S/C48H59F3N6O9S/c1-28(2)64-33-17-15-31(16-18-33)37-23-34(24-38(53-37)36-14-10-11-21-52-36)65-35-25-39-41(58)55-47(43(60)56-67(62,63)46(7)19-20-46)26-32(47)13-9-8-12-29(3)22-30(4)40(42(59)57(39)27-35)54-44(61)66-45(5,6)48(49,50)51/h9-11,13-18,21,23-24,28-30,32,35,39-40H,8,12,19-20,22,25-27H2,1-7H3,(H,54,61)(H,55,58)(H,56,60)/b13-9-/t29-,30+,32?,35+,39-,40-,47+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229546
(US9334279, 1022)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)cc(n1)-c1ccccn1 |r,c:42| Show InChI InChI=1S/C48H59F3N6O9S/c1-28(2)64-33-17-15-31(16-18-33)37-23-34(24-38(53-37)36-14-10-11-21-52-36)65-35-25-39-41(58)55-47(43(60)56-67(62,63)46(7)19-20-46)26-32(47)13-9-8-12-29(3)22-30(4)40(42(59)57(39)27-35)54-44(61)66-45(5,6)48(49,50)51/h9-11,13-18,21,23-24,28-30,32,35,39-40H,8,12,19-20,22,25-27H2,1-7H3,(H,54,61)(H,55,58)(H,56,60)/b13-9-/t29-,30+,32?,35+,39-,40-,47+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229547
(US9334279, 1023)Show SMILES C[C@@H]1CC\C=C/[C@@H]2C[C@]2(NC(=O)[C@@H]2C[C@H](CN2C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C1)Oc1cc(nc(c1)-c1nccs1)-c1nccs1)C(=O)NS(=O)(=O)C1(C)CC1 |r,c:4| Show InChI InChI=1S/C40H48F3N7O8S3/c1-22-8-6-7-9-24-20-39(24,35(53)49-61(55,56)38(5)10-11-38)48-31(51)29-19-26(57-25-17-27(32-44-12-14-59-32)46-28(18-25)33-45-13-15-60-33)21-50(29)34(52)30(23(2)16-22)47-36(54)58-37(3,4)40(41,42)43/h7,9,12-15,17-18,22-24,26,29-30H,6,8,10-11,16,19-21H2,1-5H3,(H,47,54)(H,48,51)(H,49,53)/b9-7-/t22-,23-,24?,26-,29+,30+,39-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 0.460 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229547
(US9334279, 1023)Show SMILES C[C@@H]1CC\C=C/[C@@H]2C[C@]2(NC(=O)[C@@H]2C[C@H](CN2C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C1)Oc1cc(nc(c1)-c1nccs1)-c1nccs1)C(=O)NS(=O)(=O)C1(C)CC1 |r,c:4| Show InChI InChI=1S/C40H48F3N7O8S3/c1-22-8-6-7-9-24-20-39(24,35(53)49-61(55,56)38(5)10-11-38)48-31(51)29-19-26(57-25-17-27(32-44-12-14-59-32)46-28(18-25)33-45-13-15-60-33)21-50(29)34(52)30(23(2)16-22)47-36(54)58-37(3,4)40(41,42)43/h7,9,12-15,17-18,22-24,26,29-30H,6,8,10-11,16,19-21H2,1-5H3,(H,47,54)(H,48,51)(H,49,53)/b9-7-/t22-,23-,24?,26-,29+,30+,39-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 0.400 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229548
(US9334279, 1024)Show SMILES C[C@H]1CC\C=C/[C@@H]2C[C@]2(NC(=O)[C@@H]2C[C@H](CN2C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C1)Oc1cc(nc(c1)-c1nccs1)-c1nccs1)C(=O)NS(=O)(=O)C1(C)CC1 |r,c:4| Show InChI InChI=1S/C40H48F3N7O8S3/c1-22-8-6-7-9-24-20-39(24,35(53)49-61(55,56)38(5)10-11-38)48-31(51)29-19-26(57-25-17-27(32-44-12-14-59-32)46-28(18-25)33-45-13-15-60-33)21-50(29)34(52)30(23(2)16-22)47-36(54)58-37(3,4)40(41,42)43/h7,9,12-15,17-18,22-24,26,29-30H,6,8,10-11,16,19-21H2,1-5H3,(H,47,54)(H,48,51)(H,49,53)/b9-7-/t22-,23+,24?,26+,29-,30-,39+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229548
(US9334279, 1024)Show SMILES C[C@H]1CC\C=C/[C@@H]2C[C@]2(NC(=O)[C@@H]2C[C@H](CN2C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C1)Oc1cc(nc(c1)-c1nccs1)-c1nccs1)C(=O)NS(=O)(=O)C1(C)CC1 |r,c:4| Show InChI InChI=1S/C40H48F3N7O8S3/c1-22-8-6-7-9-24-20-39(24,35(53)49-61(55,56)38(5)10-11-38)48-31(51)29-19-26(57-25-17-27(32-44-12-14-59-32)46-28(18-25)33-45-13-15-60-33)21-50(29)34(52)30(23(2)16-22)47-36(54)58-37(3,4)40(41,42)43/h7,9,12-15,17-18,22-24,26,29-30H,6,8,10-11,16,19-21H2,1-5H3,(H,47,54)(H,48,51)(H,49,53)/b9-7-/t22-,23+,24?,26+,29-,30-,39+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 0.75 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229549
(US9334279, 1025)Show SMILES C[C@@H]1CC\C=C/[C@@H]2C[C@]2(NC(=O)[C@@H]2C[C@H](CN2C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C1)Oc1ccnc(c1)-c1nccs1)C(=O)NS(=O)(=O)C1(C)CC1 |r,c:4| Show InChI InChI=1S/C37H47F3N6O8S2/c1-21-8-6-7-9-23-19-36(23,32(49)45-56(51,52)35(5)11-12-35)44-29(47)27-18-25(53-24-10-13-41-26(17-24)30-42-14-15-55-30)20-46(27)31(48)28(22(2)16-21)43-33(50)54-34(3,4)37(38,39)40/h7,9-10,13-15,17,21-23,25,27-28H,6,8,11-12,16,18-20H2,1-5H3,(H,43,50)(H,44,47)(H,45,49)/b9-7-/t21-,22-,23?,25-,27+,28+,36-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229549
(US9334279, 1025)Show SMILES C[C@@H]1CC\C=C/[C@@H]2C[C@]2(NC(=O)[C@@H]2C[C@H](CN2C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C1)Oc1ccnc(c1)-c1nccs1)C(=O)NS(=O)(=O)C1(C)CC1 |r,c:4| Show InChI InChI=1S/C37H47F3N6O8S2/c1-21-8-6-7-9-23-19-36(23,32(49)45-56(51,52)35(5)11-12-35)44-29(47)27-18-25(53-24-10-13-41-26(17-24)30-42-14-15-55-30)20-46(27)31(48)28(22(2)16-21)43-33(50)54-34(3,4)37(38,39)40/h7,9-10,13-15,17,21-23,25,27-28H,6,8,11-12,16,18-20H2,1-5H3,(H,43,50)(H,44,47)(H,45,49)/b9-7-/t21-,22-,23?,25-,27+,28+,36-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 0.75 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229550
(US9334279, 1026)Show SMILES C[C@@H]1CC\C=C/[C@@H]2C[C@]2(NC(=O)[C@@H]2C[C@H](CN2C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C1)Oc1cc(Cl)ccn1)C(=O)NS(=O)(=O)C1CC1 |r,c:4| Show InChI InChI=1S/C33H43ClF3N5O8S/c1-18-7-5-6-8-20-16-32(20,29(45)41-51(47,48)23-9-10-23)40-27(43)24-15-22(49-25-14-21(34)11-12-38-25)17-42(24)28(44)26(19(2)13-18)39-30(46)50-31(3,4)33(35,36)37/h6,8,11-12,14,18-20,22-24,26H,5,7,9-10,13,15-17H2,1-4H3,(H,39,46)(H,40,43)(H,41,45)/b8-6-/t18-,19-,20?,22-,24+,26+,32-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229550
(US9334279, 1026)Show SMILES C[C@@H]1CC\C=C/[C@@H]2C[C@]2(NC(=O)[C@@H]2C[C@H](CN2C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C1)Oc1cc(Cl)ccn1)C(=O)NS(=O)(=O)C1CC1 |r,c:4| Show InChI InChI=1S/C33H43ClF3N5O8S/c1-18-7-5-6-8-20-16-32(20,29(45)41-51(47,48)23-9-10-23)40-27(43)24-15-22(49-25-14-21(34)11-12-38-25)17-42(24)28(44)26(19(2)13-18)39-30(46)50-31(3,4)33(35,36)37/h6,8,11-12,14,18-20,22-24,26H,5,7,9-10,13,15-17H2,1-4H3,(H,39,46)(H,40,43)(H,41,45)/b8-6-/t18-,19-,20?,22-,24+,26+,32-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229551
(US9334279, 1027)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(Cl)cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)n1 |r,c:45| Show InChI InChI=1S/C43H55ClF3N5O9S/c1-24(2)59-30-14-12-27(13-15-30)32-19-29(44)20-34(48-32)60-31-21-33-36(53)50-42(38(55)51-62(57,58)41(7)16-17-41)22-28(42)11-9-8-10-25(3)18-26(4)35(37(54)52(33)23-31)49-39(56)61-40(5,6)43(45,46)47/h9,11-15,19-20,24-26,28,31,33,35H,8,10,16-18,21-23H2,1-7H3,(H,49,56)(H,50,53)(H,51,55)/b11-9-/t25-,26-,28?,31-,33+,35+,42-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1028-1200,1251-1711]
(Hepatitis C virus genotype 1b (strain J4L2S) (HCV)) | BDBM229551
(US9334279, 1027)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(Cl)cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)n1 |r,c:45| Show InChI InChI=1S/C43H55ClF3N5O9S/c1-24(2)59-30-14-12-27(13-15-30)32-19-29(44)20-34(48-32)60-31-21-33-36(53)50-42(38(55)51-62(57,58)41(7)16-17-41)22-28(42)11-9-8-10-25(3)18-26(4)35(37(54)52(33)23-31)49-39(56)61-40(5,6)43(45,46)47/h9,11-15,19-20,24-26,28,31,33,35H,8,10,16-18,21-23H2,1-7H3,(H,49,56)(H,50,53)(H,51,55)/b11-9-/t25-,26-,28?,31-,33+,35+,42-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Company
US Patent
| |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Genome polyprotein [1027-1711]
(Hepatitis C virus genotype 1a (strain H77) (HCV)) | BDBM229552
(US9334279, 1028)Show SMILES CC(C)Oc1ccc(cc1)-c1cc(Cl)cc(O[C@@H]2C[C@@H]3N(C2)C(=O)[C@@H](NC(=O)OC(C)(C)C(F)(F)F)[C@H](C)C[C@@H](C)CC\C=C/[C@@H]2C[C@]2(NC3=O)C(=O)NS(=O)(=O)C2(C)CC2)n1 |r,c:45| Show InChI InChI=1S/C43H55ClF3N5O9S/c1-24(2)59-30-14-12-27(13-15-30)32-19-29(44)20-34(48-32)60-31-21-33-36(53)50-42(38(55)51-62(57,58)41(7)16-17-41)22-28(42)11-9-8-10-25(3)18-26(4)35(37(54)52(33)23-31)49-39(56)61-40(5,6)43(45,46)47/h9,11-15,19-20,24-26,28,31,33,35H,8,10,16-18,21-23H2,1-7H3,(H,49,56)(H,50,53)(H,51,55)/b11-9-/t25-,26+,28?,31+,33-,35-,42+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | n/a | n/a | 197 | n/a | n/a | n/a | 37 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
HCV replicon luciferase assays were developed to monitor the inhibitory effects of compounds described in the disclosure on HCV genotypes 1a and 1b v... |
US Patent US9334279 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R1W |
More data for this
Ligand-Target Pair | |
Search and Browse
