Compile Data Set for Download or QSAR

Found 30 hits Enz. Inhib. hit(s) with all data for entry = 50005477   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil elastase (Homo sapiens (Human))	BDBM50037338 (CHEMBL325234 | {6-(3-Chloro-phenyl)-2-oxo-1-[(3,3,...) Show SMILES CC(C)C(NC(=O)Cn1c(ccc(NC(=O)OCc2ccccc2)c1=O)-c1cccc(Cl)c1)C(=O)C(F)(F)F Show InChI InChI=1S/C27H25ClF3N3O5/c1-16(2)23(24(36)27(29,30)31)33-22(35)14-34-21(18-9-6-10-19(28)13-18)12-11-20(25(34)37)32-26(38)39-15-17-7-4-3-5-8-17/h3-13,16,23H,14-15H2,1-2H3,(H,32,38)(H,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50037340 (CHEMBL112880 | {6-(3,5-Dimethoxy-phenyl)-2-oxo-1-[...) Show SMILES COc1cc(OC)cc(c1)-c1ccc(NC(=O)OCc2ccccc2)c(=O)n1CC(=O)NC(C(C)C)C(=O)C(F)(F)F Show InChI InChI=1S/C29H30F3N3O7/c1-17(2)25(26(37)29(30,31)32)34-24(36)15-35-23(19-12-20(40-3)14-21(13-19)41-4)11-10-22(27(35)38)33-28(39)42-16-18-8-6-5-7-9-18/h5-14,17,25H,15-16H2,1-4H3,(H,33,39)(H,34,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50037333 (CHEMBL113132 | {6-(3-tert-Butoxy-phenyl)-2-oxo-1-[...) Show SMILES CC(C)C(NC(=O)Cn1c(ccc(NC(=O)OCc2ccccc2)c1=O)-c1cccc(OC(C)(C)C)c1)C(=O)C(F)(F)F Show InChI InChI=1S/C31H34F3N3O6/c1-19(2)26(27(39)31(32,33)34)36-25(38)17-37-24(21-12-9-13-22(16-21)43-30(3,4)5)15-14-23(28(37)40)35-29(41)42-18-20-10-7-6-8-11-20/h6-16,19,26H,17-18H2,1-5H3,(H,35,41)(H,36,38)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50036127 (CHEMBL11391 | {2-Oxo-6-phenyl-1-[(3,3,3-trifluoro-...) Show SMILES CC(C)C(NC(=O)Cn1c(ccc(NC(=O)OCc2ccccc2)c1=O)-c1ccccc1)C(=O)C(F)(F)F Show InChI InChI=1S/C27H26F3N3O5/c1-17(2)23(24(35)27(28,29)30)32-22(34)15-33-21(19-11-7-4-8-12-19)14-13-20(25(33)36)31-26(37)38-16-18-9-5-3-6-10-18/h3-14,17,23H,15-16H2,1-2H3,(H,31,37)(H,32,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50037327 (CHEMBL113321 | {6-(3-Hydroxy-phenyl)-2-oxo-1-[(3,3...) Show SMILES CC(C)C(NC(=O)Cn1c(ccc(NC(=O)OCc2ccccc2)c1=O)-c1cccc(O)c1)C(=O)C(F)(F)F Show InChI InChI=1S/C27H26F3N3O6/c1-16(2)23(24(36)27(28,29)30)32-22(35)14-33-21(18-9-6-10-19(34)13-18)12-11-20(25(33)37)31-26(38)39-15-17-7-4-3-5-8-17/h3-13,16,23,34H,14-15H2,1-2H3,(H,31,38)(H,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50037325 (CHEMBL113261 | {6-(4-Chloro-phenyl)-2-oxo-1-[(3,3,...) Show SMILES CC(C)C(NC(=O)Cn1c(ccc(NC(=O)OCc2ccccc2)c1=O)-c1ccc(Cl)cc1)C(=O)C(F)(F)F Show InChI InChI=1S/C27H25ClF3N3O5/c1-16(2)23(24(36)27(29,30)31)33-22(35)14-34-21(18-8-10-19(28)11-9-18)13-12-20(25(34)37)32-26(38)39-15-17-6-4-3-5-7-17/h3-13,16,23H,14-15H2,1-2H3,(H,32,38)(H,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50037339 (CHEMBL113171 | {6-(4-Methoxy-phenyl)-2-oxo-1-[(3,3...) Show SMILES COc1ccc(cc1)-c1ccc(NC(=O)OCc2ccccc2)c(=O)n1CC(=O)NC(C(C)C)C(=O)C(F)(F)F Show InChI InChI=1S/C28H28F3N3O6/c1-17(2)24(25(36)28(29,30)31)33-23(35)15-34-22(19-9-11-20(39-3)12-10-19)14-13-21(26(34)37)32-27(38)40-16-18-7-5-4-6-8-18/h4-14,17,24H,15-16H2,1-3H3,(H,32,38)(H,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50037335 (CHEMBL418822 | {6-Oxo-1-[(3,3,3-trifluoro-1-isopro...) Show SMILES CC(C)C(NC(=O)Cn1c(ccc(NC(=O)OCc2ccccc2)c1=O)-c1cccnc1)C(=O)C(F)(F)F Show InChI InChI=1S/C26H25F3N4O5/c1-16(2)22(23(35)26(27,28)29)32-21(34)14-33-20(18-9-6-12-30-13-18)11-10-19(24(33)36)31-25(37)38-15-17-7-4-3-5-8-17/h3-13,16,22H,14-15H2,1-2H3,(H,31,37)(H,32,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50037336 (CHEMBL432961 | {6-(2-Chloro-phenyl)-2-oxo-1-[(3,3,...) Show SMILES CC(C)C(NC(=O)Cn1c(ccc(NC(=O)OCc2ccccc2)c1=O)-c1ccccc1Cl)C(=O)C(F)(F)F Show InChI InChI=1S/C27H25ClF3N3O5/c1-16(2)23(24(36)27(29,30)31)33-22(35)14-34-21(18-10-6-7-11-19(18)28)13-12-20(25(34)37)32-26(38)39-15-17-8-4-3-5-9-17/h3-13,16,23H,14-15H2,1-2H3,(H,32,38)(H,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50037329 (CHEMBL432442 | {2-Oxo-6-p-tolyl-1-[(3,3,3-trifluor...) Show SMILES CC(C)C(NC(=O)Cn1c(ccc(NC(=O)OCc2ccccc2)c1=O)-c1ccc(C)cc1)C(=O)C(F)(F)F Show InChI InChI=1S/C28H28F3N3O5/c1-17(2)24(25(36)28(29,30)31)33-23(35)15-34-22(20-11-9-18(3)10-12-20)14-13-21(26(34)37)32-27(38)39-16-19-7-5-4-6-8-19/h4-14,17,24H,15-16H2,1-3H3,(H,32,38)(H,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50037326 (3-{5-Benzyloxycarbonylamino-6-oxo-1-[(3,3,3-triflu...) Show SMILES CC(C)C(NC(=O)Cn1c(ccc(NC(=O)OCc2ccccc2)c1=O)-c1cccc(c1)C(O)=O)C(=O)C(F)(F)F Show InChI InChI=1S/C28H26F3N3O7/c1-16(2)23(24(36)28(29,30)31)33-22(35)14-34-21(18-9-6-10-19(13-18)26(38)39)12-11-20(25(34)37)32-27(40)41-15-17-7-4-3-5-8-17/h3-13,16,23H,14-15H2,1-2H3,(H,32,40)(H,33,35)(H,38,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50037330 (CHEMBL326616 | {2-Oxo-6-((E)-styryl)-1-[(3,3,3-tri...) Show SMILES CC(C)C(NC(=O)Cn1c(\C=C\c2ccccc2)ccc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F Show InChI InChI=1S/C29H28F3N3O5/c1-19(2)25(26(37)29(30,31)32)34-24(36)17-35-22(14-13-20-9-5-3-6-10-20)15-16-23(27(35)38)33-28(39)40-18-21-11-7-4-8-12-21/h3-16,19,25H,17-18H2,1-2H3,(H,33,39)(H,34,36)/b14-13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50037110 (CHEMBL107291 | {5-Benzyl-2-oxo-1-[(3,3,3-trifluoro...) Show SMILES CC(C)C(NC(=O)Cn1cc(Cc2ccccc2)cc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F Show InChI InChI=1S/C28H28F3N3O5/c1-18(2)24(25(36)28(29,30)31)33-23(35)16-34-15-21(13-19-9-5-3-6-10-19)14-22(26(34)37)32-27(38)39-17-20-11-7-4-8-12-20/h3-12,14-15,18,24H,13,16-17H2,1-2H3,(H,32,38)(H,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50037331 (4-{5-Benzyloxycarbonylamino-6-oxo-1-[(3,3,3-triflu...) Show SMILES CC(C)C(NC(=O)Cn1c(ccc(NC(=O)OCc2ccccc2)c1=O)-c1ccc(cc1)C(O)=O)C(=O)C(F)(F)F Show InChI InChI=1S/C28H26F3N3O7/c1-16(2)23(24(36)28(29,30)31)33-22(35)14-34-21(18-8-10-19(11-9-18)26(38)39)13-12-20(25(34)37)32-27(40)41-15-17-6-4-3-5-7-17/h3-13,16,23H,14-15H2,1-2H3,(H,32,40)(H,33,35)(H,38,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50036127 (CHEMBL11391 | {2-Oxo-6-phenyl-1-[(3,3,3-trifluoro-...) Show SMILES CC(C)C(NC(=O)Cn1c(ccc(NC(=O)OCc2ccccc2)c1=O)-c1ccccc1)C(=O)C(F)(F)F Show InChI InChI=1S/C27H26F3N3O5/c1-17(2)23(24(35)27(28,29)30)32-22(34)15-33-21(19-11-7-4-8-12-19)14-13-20(25(33)36)31-26(37)38-16-18-9-5-3-6-10-18/h3-14,17,23H,15-16H2,1-2H3,(H,31,37)(H,32,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against bovine pancreatic chymotrypsinogen				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50037334 (CHEMBL112971 | {6-Benzyl-2-oxo-1-[(3,3,3-trifluoro...) Show SMILES CC(C)C(NC(=O)Cn1c(Cc2ccccc2)ccc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F Show InChI InChI=1S/C28H28F3N3O5/c1-18(2)24(25(36)28(29,30)31)33-23(35)16-34-21(15-19-9-5-3-6-10-19)13-14-22(26(34)37)32-27(38)39-17-20-11-7-4-8-12-20/h3-14,18,24H,15-17H2,1-2H3,(H,32,38)(H,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50037324 (CHEMBL109852 | {2-Oxo-6-phenethyl-1-[(3,3,3-triflu...) Show SMILES CC(C)C(NC(=O)Cn1c(CCc2ccccc2)ccc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F Show InChI InChI=1S/C29H30F3N3O5/c1-19(2)25(26(37)29(30,31)32)34-24(36)17-35-22(14-13-20-9-5-3-6-10-20)15-16-23(27(35)38)33-28(39)40-18-21-11-7-4-8-12-21/h3-12,15-16,19,25H,13-14,17-18H2,1-2H3,(H,33,39)(H,34,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50037109 (CHEMBL13684 | {2-Oxo-1-[(3,3,3-trifluoro-1-isoprop...) Show SMILES CC(C)C(NC(=O)Cn1cccc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F Show InChI InChI=1S/C21H22F3N3O5/c1-13(2)17(18(29)21(22,23)24)26-16(28)11-27-10-6-9-15(19(27)30)25-20(31)32-12-14-7-4-3-5-8-14/h3-10,13,17H,11-12H2,1-2H3,(H,25,31)(H,26,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50037332 (CHEMBL114024 | {2-Oxo-5-phenyl-1-[(3,3,3-trifluoro...) Show SMILES CC(C)C(NC(=O)Cn1cc(cc(NC(=O)OCc2ccccc2)c1=O)-c1ccccc1)C(=O)C(F)(F)F Show InChI InChI=1S/C27H26F3N3O5/c1-17(2)23(24(35)27(28,29)30)32-22(34)15-33-14-20(19-11-7-4-8-12-19)13-21(25(33)36)31-26(37)38-16-18-9-5-3-6-10-18/h3-14,17,23H,15-16H2,1-2H3,(H,31,37)(H,32,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50037328 (CHEMBL324587 | {2-Oxo-4-phenyl-1-[(3,3,3-trifluoro...) Show SMILES CC(C)C(NC(=O)Cn1ccc(-c2ccccc2)c(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F Show InChI InChI=1S/C27H26F3N3O5/c1-17(2)22(24(35)27(28,29)30)31-21(34)15-33-14-13-20(19-11-7-4-8-12-19)23(25(33)36)32-26(37)38-16-18-9-5-3-6-10-18/h3-14,17,22H,15-16H2,1-2H3,(H,31,34)(H,32,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50037337 (CHEMBL109769 | {6-Methyl-2-oxo-1-[(3,3,3-trifluoro...) Show SMILES CC(C)C(NC(=O)Cn1c(C)ccc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F Show InChI InChI=1S/C22H24F3N3O5/c1-13(2)18(19(30)22(23,24)25)27-17(29)11-28-14(3)9-10-16(20(28)31)26-21(32)33-12-15-7-5-4-6-8-15/h4-10,13,18H,11-12H2,1-3H3,(H,26,32)(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against human leukocyte elastase(HLE) enzyme				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50037325 (CHEMBL113261 | {6-(4-Chloro-phenyl)-2-oxo-1-[(3,3,...) Show SMILES CC(C)C(NC(=O)Cn1c(ccc(NC(=O)OCc2ccccc2)c1=O)-c1ccc(Cl)cc1)C(=O)C(F)(F)F Show InChI InChI=1S/C27H25ClF3N3O5/c1-16(2)23(24(36)27(29,30)31)33-22(35)14-34-21(18-8-10-19(28)11-9-18)13-12-20(25(34)37)32-26(38)39-15-17-6-4-3-5-7-17/h3-13,16,23H,14-15H2,1-2H3,(H,32,38)(H,33,35)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against bovine pancreatic chymotrypsinogen				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50037329 (CHEMBL432442 | {2-Oxo-6-p-tolyl-1-[(3,3,3-trifluor...) Show SMILES CC(C)C(NC(=O)Cn1c(ccc(NC(=O)OCc2ccccc2)c1=O)-c1ccc(C)cc1)C(=O)C(F)(F)F Show InChI InChI=1S/C28H28F3N3O5/c1-17(2)24(25(36)28(29,30)31)33-23(35)15-34-22(20-11-9-18(3)10-12-20)14-13-21(26(34)37)32-27(38)39-16-19-7-5-4-6-8-19/h4-14,17,24H,15-16H2,1-3H3,(H,32,38)(H,33,35)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	720	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against bovine pancreatic chymotrypsinogen				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Chymotrypsin-like elastase family member 2A (Sus scrofa)	BDBM50036127 (CHEMBL11391 | {2-Oxo-6-phenyl-1-[(3,3,3-trifluoro-...) Show SMILES CC(C)C(NC(=O)Cn1c(ccc(NC(=O)OCc2ccccc2)c1=O)-c1ccccc1)C(=O)C(F)(F)F Show InChI InChI=1S/C27H26F3N3O5/c1-17(2)23(24(35)27(28,29)30)32-22(34)15-33-21(19-11-7-4-8-12-19)14-13-20(25(33)36)31-26(37)38-16-18-9-5-3-6-10-18/h3-14,17,23H,15-16H2,1-2H3,(H,31,37)(H,32,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibitory activity against porcine pancreatic elastase				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Anionic trypsin (Bos taurus)	BDBM50036127 (CHEMBL11391 | {2-Oxo-6-phenyl-1-[(3,3,3-trifluoro-...) Show SMILES CC(C)C(NC(=O)Cn1c(ccc(NC(=O)OCc2ccccc2)c1=O)-c1ccccc1)C(=O)C(F)(F)F Show InChI InChI=1S/C27H26F3N3O5/c1-17(2)23(24(35)27(28,29)30)32-22(34)15-33-21(19-11-7-4-8-12-19)14-13-20(25(33)36)31-26(37)38-16-18-9-5-3-6-10-18/h3-14,17,23H,15-16H2,1-2H3,(H,31,37)(H,32,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibitory activity against bovine pancreatic trypsin				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50037330 (CHEMBL326616 | {2-Oxo-6-((E)-styryl)-1-[(3,3,3-tri...) Show SMILES CC(C)C(NC(=O)Cn1c(\C=C\c2ccccc2)ccc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F Show InChI InChI=1S/C29H28F3N3O5/c1-19(2)25(26(37)29(30,31)32)34-24(36)17-35-22(14-13-20-9-5-3-6-10-20)15-16-23(27(35)38)33-28(39)40-18-21-11-7-4-8-12-21/h3-16,19,25H,17-18H2,1-2H3,(H,33,39)(H,34,36)/b14-13+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against bovine pancreatic chymotrypsinogen				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50037110 (CHEMBL107291 | {5-Benzyl-2-oxo-1-[(3,3,3-trifluoro...) Show SMILES CC(C)C(NC(=O)Cn1cc(Cc2ccccc2)cc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F Show InChI InChI=1S/C28H28F3N3O5/c1-18(2)24(25(36)28(29,30)31)33-23(35)16-34-15-21(13-19-9-5-3-6-10-19)14-22(26(34)37)32-27(38)39-17-20-11-7-4-8-12-20/h3-12,14-15,18,24H,13,16-17H2,1-2H3,(H,32,38)(H,33,35)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against bovine pancreatic chymotrypsinogen				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Papain (Carica papaya)	BDBM50036127 (CHEMBL11391 | {2-Oxo-6-phenyl-1-[(3,3,3-trifluoro-...) Show SMILES CC(C)C(NC(=O)Cn1c(ccc(NC(=O)OCc2ccccc2)c1=O)-c1ccccc1)C(=O)C(F)(F)F Show InChI InChI=1S/C27H26F3N3O5/c1-17(2)23(24(35)27(28,29)30)32-22(34)15-33-21(19-11-7-4-8-12-19)14-13-20(25(33)36)31-26(37)38-16-18-9-5-3-6-10-18/h3-14,17,23H,15-16H2,1-2H3,(H,31,37)(H,32,34)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Inhibitory activity against papain				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50037324 (CHEMBL109852 | {2-Oxo-6-phenethyl-1-[(3,3,3-triflu...) Show SMILES CC(C)C(NC(=O)Cn1c(CCc2ccccc2)ccc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F Show InChI InChI=1S/C29H30F3N3O5/c1-19(2)25(26(37)29(30,31)32)34-24(36)17-35-22(14-13-20-9-5-3-6-10-20)15-16-23(27(35)38)33-28(39)40-18-21-11-7-4-8-12-21/h3-12,15-16,19,25H,13-14,17-18H2,1-2H3,(H,33,39)(H,34,36)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against bovine pancreatic chymotrypsinogen				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair
Chymotrypsin-C (Homo sapiens (Human))	BDBM50037109 (CHEMBL13684 | {2-Oxo-1-[(3,3,3-trifluoro-1-isoprop...) Show SMILES CC(C)C(NC(=O)Cn1cccc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F Show InChI InChI=1S/C21H22F3N3O5/c1-13(2)17(18(29)21(22,23)24)26-16(28)11-27-10-6-9-15(19(27)30)25-20(31)32-12-14-7-4-3-5-8-14/h3-10,13,17H,11-12H2,1-2H3,(H,25,31)(H,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ZENECA Pharmaceuticals Group Curated by ChEMBL					Assay Description Tested for inhibitory activity against bovine pancreatic chymotrypsinogen				J Med Chem 37: 3303-12 (1994) BindingDB Entry DOI: 10.7270/Q2SB44SP
					More data for this Ligand-Target Pair