Found 13 hits Enz. Inhib. hit(s) with all data for entry = 50044183 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Fe(3+)-Zn(2+) purple acid phosphatase
(Phaseolus vulgaris) | BDBM50162816
(CHEMBL180570 | Medronic acid | Methylene diphsphon...)Show InChI InChI=1S/CH6O6P2/c2-8(3,4)1-9(5,6)7/h1H2,(H2,2,3,4)(H2,5,6,7) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 1.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of red kidney beans purple acid phosphatase |
Eur J Med Chem 76: 132-44 (2014)
Article DOI: 10.1016/j.ejmech.2014.02.008 BindingDB Entry DOI: 10.7270/Q2T43VM0 |
More data for this Ligand-Target Pair | |
Fe(3+)-Zn(2+) purple acid phosphatase
(Phaseolus vulgaris) | BDBM50311531
((2-Carboxyethyl)-phosphonic acid | 3-PHOSPHONOPROP...)Show InChI InChI=1S/C3H7O5P/c4-3(5)1-2-9(6,7)8/h1-2H2,(H,4,5)(H2,6,7,8) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
| Article PubMed
| 1.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of red kidney beans purple acid phosphatase |
Eur J Med Chem 76: 132-44 (2014)
Article DOI: 10.1016/j.ejmech.2014.02.008 BindingDB Entry DOI: 10.7270/Q2T43VM0 |
More data for this Ligand-Target Pair | |
Fe(3+)-Zn(2+) purple acid phosphatase
(Phaseolus vulgaris) | BDBM50008089
(CHEBI:15732 | FOSFONET)Show InChI InChI=1S/C2H5O5P/c3-2(4)1-8(5,6)7/h1H2,(H,3,4)(H2,5,6,7) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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DrugBank MCE KEGG PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 5.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of red kidney beans purple acid phosphatase |
Eur J Med Chem 76: 132-44 (2014)
Article DOI: 10.1016/j.ejmech.2014.02.008 BindingDB Entry DOI: 10.7270/Q2T43VM0 |
More data for this Ligand-Target Pair | |
Fe(3+)-Zn(2+) purple acid phosphatase
(Phaseolus vulgaris) | BDBM84557
(Phosphate analogue, 6)Show InChI InChI=1S/C2H7O3P/c1-2-6(3,4)5/h2H2,1H3,(H2,3,4,5) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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PC cid PC sid UniChem
Patents
| Article PubMed
| 7.60E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of red kidney beans purple acid phosphatase |
Eur J Med Chem 76: 132-44 (2014)
Article DOI: 10.1016/j.ejmech.2014.02.008 BindingDB Entry DOI: 10.7270/Q2T43VM0 |
More data for this Ligand-Target Pair | |
Metallo-beta-lactamase type 2
(Bacteroides fragilis) | BDBM50008094
(CHEMBL3234724)Show InChI InChI=1S/C6H15NO4S/c8-12(9,10)6-3-7-1-4-11-5-2-7/h8-10H,1-6H2 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.30E+7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Competitive inhibition of Bacteroides fragilis metallo-beta-lactamase CcrA |
Eur J Med Chem 76: 132-44 (2014)
Article DOI: 10.1016/j.ejmech.2014.02.008 BindingDB Entry DOI: 10.7270/Q2T43VM0 |
More data for this Ligand-Target Pair | |
Metallo-beta-lactamase type 2
(Bacteroides fragilis) | BDBM50008098
(CHEMBL3234725)Show SMILES C(c1ccc(cc1)-c1ccccc1-c1nnn[nH]1)n1c2ccccc2c2ccccc12 Show InChI InChI=1S/C26H19N5/c1-2-10-23(26-27-29-30-28-26)20(7-1)19-15-13-18(14-16-19)17-31-24-11-5-3-8-21(24)22-9-4-6-12-25(22)31/h1-16H,17H2,(H,27,28,29,30) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Competitive inhibition of Bacteroides fragilis metallo-beta-lactamase CcrA |
Eur J Med Chem 76: 132-44 (2014)
Article DOI: 10.1016/j.ejmech.2014.02.008 BindingDB Entry DOI: 10.7270/Q2T43VM0 |
More data for this Ligand-Target Pair | |
Metallo-beta-lactamase L1 type 3
(Stenotrophomonas maltophilia) | BDBM50008093
(CHEMBL3234717)Show SMILES COC(=O)C(CSc1cc(C(=O)OC)c2nc3cccc(C(O)=O)c3nc2c1)NC(C)=O Show InChI InChI=1S/C21H19N3O7S/c1-10(25)22-16(21(29)31-3)9-32-11-7-13(20(28)30-2)18-15(8-11)24-17-12(19(26)27)5-4-6-14(17)23-18/h4-8,16H,9H2,1-3H3,(H,22,25)(H,26,27) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of Stenotrophomonas maltophilia metallo-beta-lactamase L1 after 5 mins |
Eur J Med Chem 76: 132-44 (2014)
Article DOI: 10.1016/j.ejmech.2014.02.008 BindingDB Entry DOI: 10.7270/Q2T43VM0 |
More data for this Ligand-Target Pair | |
Metallo-beta-lactamase L1 type 3
(Stenotrophomonas maltophilia) | BDBM50008090
(CHEMBL3234716)Show InChI InChI=1S/C15H10N2O5/c1-22-15(21)11-10(18)6-5-9-13(11)17-8-4-2-3-7(14(19)20)12(8)16-9/h2-6,18H,1H3,(H,19,20) | PDB MMDB
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of Stenotrophomonas maltophilia metallo-beta-lactamase L1 after 5 mins |
Eur J Med Chem 76: 132-44 (2014)
Article DOI: 10.1016/j.ejmech.2014.02.008 BindingDB Entry DOI: 10.7270/Q2T43VM0 |
More data for this Ligand-Target Pair | |
Arginase-1
(Rattus norvegicus) | BDBM50008099
(CHEMBL1234777)Show InChI InChI=1S/C5H12N4O3/c6-3(4(10)11)1-2-8-5(7)9-12/h3,12H,1-2,6H2,(H,10,11)(H3,7,8,9)/t3-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of rat liver arginase |
Eur J Med Chem 76: 132-44 (2014)
Article DOI: 10.1016/j.ejmech.2014.02.008 BindingDB Entry DOI: 10.7270/Q2T43VM0 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Fe(3+)-Zn(2+) purple acid phosphatase
(Phaseolus vulgaris) | BDBM50008082
(CHEMBL1794623)Show InChI InChI=1S/CH5O3PS/c2-5(3,4)1-6/h6H,1H2,(H2,2,3,4) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of red kidney beans purple acid phosphatase |
Eur J Med Chem 76: 132-44 (2014)
Article DOI: 10.1016/j.ejmech.2014.02.008 BindingDB Entry DOI: 10.7270/Q2T43VM0 |
More data for this Ligand-Target Pair | |
Fe(3+)-Zn(2+) purple acid phosphatase
(Phaseolus vulgaris) | BDBM50008087
(CHEMBL3234430)Show InChI InChI=1S/C3H9O3PS/c4-7(5,6)2-1-3-8/h8H,1-3H2,(H2,4,5,6) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of red kidney beans purple acid phosphatase |
Eur J Med Chem 76: 132-44 (2014)
Article DOI: 10.1016/j.ejmech.2014.02.008 BindingDB Entry DOI: 10.7270/Q2T43VM0 |
More data for this Ligand-Target Pair | |
Fe(3+)-Zn(2+) purple acid phosphatase
(Phaseolus vulgaris) | BDBM50322604
(2-mercaptophenylphosphonic acid | CHEMBL1173336)Show InChI InChI=1S/C6H7O3PS/c7-10(8,9)5-3-1-2-4-6(5)11/h1-4,11H,(H2,7,8,9) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 3.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of red kidney beans purple acid phosphatase |
Eur J Med Chem 76: 132-44 (2014)
Article DOI: 10.1016/j.ejmech.2014.02.008 BindingDB Entry DOI: 10.7270/Q2T43VM0 |
More data for this Ligand-Target Pair | |
Fe(3+)-Zn(2+) purple acid phosphatase
(Phaseolus vulgaris) | BDBM50008086
(CHEMBL3234429)Show InChI InChI=1S/C2H7O3PS/c3-6(4,5)1-2-7/h7H,1-2H2,(H2,3,4,5) | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description Inhibition of red kidney beans purple acid phosphatase |
Eur J Med Chem 76: 132-44 (2014)
Article DOI: 10.1016/j.ejmech.2014.02.008 BindingDB Entry DOI: 10.7270/Q2T43VM0 |
More data for this Ligand-Target Pair | |