Found 36 hits Enz. Inhib. hit(s) with all data for entry = 50044453 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017594
(CHEMBL3288626)Show SMILES C[C@@H](NC(=S)NC[C@@H](COC(=O)C(C)(C)C)Cc1ccc(C)c(C)c1)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C27H39N3O4S2/c1-18-8-9-21(14-19(18)2)15-22(17-34-25(31)27(4,5)6)16-28-26(35)29-20(3)23-10-12-24(13-11-23)30-36(7,32)33/h8-14,20,22,30H,15-17H2,1-7H3,(H2,28,29,35)/t20-,22+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from rat TRPV1 after 60 mins by competitive binding assay |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017592
(CHEMBL3288624)Show SMILES C[C@@H](NC(=S)NCC(COC(=O)C(C)(C)C)Cc1ccc(C)c(C)c1)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C27H39N3O4S2/c1-18-8-9-21(14-19(18)2)15-22(17-34-25(31)27(4,5)6)16-28-26(35)29-20(3)23-10-12-24(13-11-23)30-36(7,32)33/h8-14,20,22,30H,15-17H2,1-7H3,(H2,28,29,35)/t20-,22?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from rat TRPV1 after 60 mins by competitive binding assay |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017581
(CHEMBL3288631)Show SMILES C[C@@H](NC(=S)NC[C@@H](COC(=O)C(C)(C)C)Cc1ccc(cc1)C(C)(C)C)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C29H43N3O4S2/c1-20(23-11-15-25(16-12-23)32-38(8,34)35)31-27(37)30-18-22(19-36-26(33)29(5,6)7)17-21-9-13-24(14-10-21)28(2,3)4/h9-16,20,22,32H,17-19H2,1-8H3,(H2,30,31,37)/t20-,22+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from rat TRPV1 after 60 mins by competitive binding assay |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017592
(CHEMBL3288624)Show SMILES C[C@@H](NC(=S)NCC(COC(=O)C(C)(C)C)Cc1ccc(C)c(C)c1)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C27H39N3O4S2/c1-18-8-9-21(14-19(18)2)15-22(17-34-25(31)27(4,5)6)16-28-26(35)29-20(3)23-10-12-24(13-11-23)30-36(7,32)33/h8-14,20,22,30H,15-17H2,1-7H3,(H2,28,29,35)/t20-,22?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity at rat TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced [45Ca2+] uptake by liquid scintill... |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017593
(CHEMBL3288625)Show SMILES C[C@@H](NC(=S)NC[C@H](COC(=O)C(C)(C)C)Cc1ccc(C)c(C)c1)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C27H39N3O4S2/c1-18-8-9-21(14-19(18)2)15-22(17-34-25(31)27(4,5)6)16-28-26(35)29-20(3)23-10-12-24(13-11-23)30-36(7,32)33/h8-14,20,22,30H,15-17H2,1-7H3,(H2,28,29,35)/t20-,22-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 7.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity at rat TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced [45Ca2+] uptake by liquid scintill... |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017579
(CHEMBL3288629)Show SMILES C[C@@H](NC(=S)NCC(COC(=O)C(C)(C)C)Cc1ccc(cc1)C(C)(C)C)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C29H43N3O4S2/c1-20(23-11-15-25(16-12-23)32-38(8,34)35)31-27(37)30-18-22(19-36-26(33)29(5,6)7)17-21-9-13-24(14-10-21)28(2,3)4/h9-16,20,22,32H,17-19H2,1-8H3,(H2,30,31,37)/t20-,22?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from rat TRPV1 after 60 mins by competitive binding assay |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017594
(CHEMBL3288626)Show SMILES C[C@@H](NC(=S)NC[C@@H](COC(=O)C(C)(C)C)Cc1ccc(C)c(C)c1)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C27H39N3O4S2/c1-18-8-9-21(14-19(18)2)15-22(17-34-25(31)27(4,5)6)16-28-26(35)29-20(3)23-10-12-24(13-11-23)30-36(7,32)33/h8-14,20,22,30H,15-17H2,1-7H3,(H2,28,29,35)/t20-,22+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity at rat TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced [45Ca2+] uptake by liquid scintill... |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017593
(CHEMBL3288625)Show SMILES C[C@@H](NC(=S)NC[C@H](COC(=O)C(C)(C)C)Cc1ccc(C)c(C)c1)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C27H39N3O4S2/c1-18-8-9-21(14-19(18)2)15-22(17-34-25(31)27(4,5)6)16-28-26(35)29-20(3)23-10-12-24(13-11-23)30-36(7,32)33/h8-14,20,22,30H,15-17H2,1-7H3,(H2,28,29,35)/t20-,22-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from rat TRPV1 after 60 mins by competitive binding assay |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017580
(CHEMBL3288630)Show SMILES C[C@@H](NC(=S)NC[C@H](COC(=O)C(C)(C)C)Cc1ccc(cc1)C(C)(C)C)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C29H43N3O4S2/c1-20(23-11-15-25(16-12-23)32-38(8,34)35)31-27(37)30-18-22(19-36-26(33)29(5,6)7)17-21-9-13-24(14-10-21)28(2,3)4/h9-16,20,22,32H,17-19H2,1-8H3,(H2,30,31,37)/t20-,22-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from rat TRPV1 after 60 mins by competitive binding assay |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017587
(CHEMBL3288619)Show SMILES C[C@@H](NC(=S)NC[C@@H](COC(=O)C(C)(C)C)Cc1ccccc1)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C25H35N3O4S2/c1-18(21-11-13-22(14-12-21)28-34(5,30)31)27-24(33)26-16-20(15-19-9-7-6-8-10-19)17-32-23(29)25(2,3)4/h6-14,18,20,28H,15-17H2,1-5H3,(H2,26,27,33)/t18-,20+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from rat TRPV1 after 60 mins by competitive binding assay |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017586
(CHEMBL3288618)Show SMILES C[C@@H](NC(=S)NC[C@H](COC(=O)C(C)(C)C)Cc1ccccc1)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C25H35N3O4S2/c1-18(21-11-13-22(14-12-21)28-34(5,30)31)27-24(33)26-16-20(15-19-9-7-6-8-10-19)17-32-23(29)25(2,3)4/h6-14,18,20,28H,15-17H2,1-5H3,(H2,26,27,33)/t18-,20-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from rat TRPV1 after 60 mins by competitive binding assay |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017579
(CHEMBL3288629)Show SMILES C[C@@H](NC(=S)NCC(COC(=O)C(C)(C)C)Cc1ccc(cc1)C(C)(C)C)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C29H43N3O4S2/c1-20(23-11-15-25(16-12-23)32-38(8,34)35)31-27(37)30-18-22(19-36-26(33)29(5,6)7)17-21-9-13-24(14-10-21)28(2,3)4/h9-16,20,22,32H,17-19H2,1-8H3,(H2,30,31,37)/t20-,22?/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity at rat TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced [45Ca2+] uptake by liquid scintill... |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017591
(CHEMBL3288623)Show SMILES CC(NC(=S)NCC(COC(=O)C(C)(C)C)Cc1ccc(C)c(C)c1)c1ccc(NS(C)(=O)=O)cc1 Show InChI InChI=1S/C27H39N3O4S2/c1-18-8-9-21(14-19(18)2)15-22(17-34-25(31)27(4,5)6)16-28-26(35)29-20(3)23-10-12-24(13-11-23)30-36(7,32)33/h8-14,20,22,30H,15-17H2,1-7H3,(H2,28,29,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity at rat TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced [45Ca2+] uptake by liquid scintill... |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017590
(CHEMBL3288622)Show SMILES Cc1ccc(C[C@H](CNC(=S)NCc2ccc(NS(C)(=O)=O)cc2)COC(=O)C(C)(C)C)cc1C |r| Show InChI InChI=1S/C26H37N3O4S2/c1-18-7-8-21(13-19(18)2)14-22(17-33-24(30)26(3,4)5)16-28-25(34)27-15-20-9-11-23(12-10-20)29-35(6,31)32/h7-13,22,29H,14-17H2,1-6H3,(H2,27,28,34)/t22-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from rat TRPV1 after 60 mins by competitive binding assay |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017578
(CHEMBL3288628)Show SMILES CC(NC(=S)NCC(COC(=O)C(C)(C)C)Cc1ccc(cc1)C(C)(C)C)c1ccc(NS(C)(=O)=O)cc1 Show InChI InChI=1S/C29H43N3O4S2/c1-20(23-11-15-25(16-12-23)32-38(8,34)35)31-27(37)30-18-22(19-36-26(33)29(5,6)7)17-21-9-13-24(14-10-21)28(2,3)4/h9-16,20,22,32H,17-19H2,1-8H3,(H2,30,31,37) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity at rat TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced [45Ca2+] uptake by liquid scintill... |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017581
(CHEMBL3288631)Show SMILES C[C@@H](NC(=S)NC[C@@H](COC(=O)C(C)(C)C)Cc1ccc(cc1)C(C)(C)C)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C29H43N3O4S2/c1-20(23-11-15-25(16-12-23)32-38(8,34)35)31-27(37)30-18-22(19-36-26(33)29(5,6)7)17-21-9-13-24(14-10-21)28(2,3)4/h9-16,20,22,32H,17-19H2,1-8H3,(H2,30,31,37)/t20-,22+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity at rat TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced [45Ca2+] uptake by liquid scintill... |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017591
(CHEMBL3288623)Show SMILES CC(NC(=S)NCC(COC(=O)C(C)(C)C)Cc1ccc(C)c(C)c1)c1ccc(NS(C)(=O)=O)cc1 Show InChI InChI=1S/C27H39N3O4S2/c1-18-8-9-21(14-19(18)2)15-22(17-34-25(31)27(4,5)6)16-28-26(35)29-20(3)23-10-12-24(13-11-23)30-36(7,32)33/h8-14,20,22,30H,15-17H2,1-7H3,(H2,28,29,35) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from rat TRPV1 after 60 mins by competitive binding assay |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017578
(CHEMBL3288628)Show SMILES CC(NC(=S)NCC(COC(=O)C(C)(C)C)Cc1ccc(cc1)C(C)(C)C)c1ccc(NS(C)(=O)=O)cc1 Show InChI InChI=1S/C29H43N3O4S2/c1-20(23-11-15-25(16-12-23)32-38(8,34)35)31-27(37)30-18-22(19-36-26(33)29(5,6)7)17-21-9-13-24(14-10-21)28(2,3)4/h9-16,20,22,32H,17-19H2,1-8H3,(H2,30,31,37) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from rat TRPV1 after 60 mins by competitive binding assay |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017586
(CHEMBL3288618)Show SMILES C[C@@H](NC(=S)NC[C@H](COC(=O)C(C)(C)C)Cc1ccccc1)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C25H35N3O4S2/c1-18(21-11-13-22(14-12-21)28-34(5,30)31)27-24(33)26-16-20(15-19-9-7-6-8-10-19)17-32-23(29)25(2,3)4/h6-14,18,20,28H,15-17H2,1-5H3,(H2,26,27,33)/t18-,20-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 45 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity at rat TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced [45Ca2+] uptake by liquid scintill... |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017580
(CHEMBL3288630)Show SMILES C[C@@H](NC(=S)NC[C@H](COC(=O)C(C)(C)C)Cc1ccc(cc1)C(C)(C)C)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C29H43N3O4S2/c1-20(23-11-15-25(16-12-23)32-38(8,34)35)31-27(37)30-18-22(19-36-26(33)29(5,6)7)17-21-9-13-24(14-10-21)28(2,3)4/h9-16,20,22,32H,17-19H2,1-8H3,(H2,30,31,37)/t20-,22-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 53 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity at rat TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced [45Ca2+] uptake by liquid scintill... |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017595
(CHEMBL3288627)Show SMILES CC(C)(C)C(=O)OC[C@@H](CNC(=S)NCc1ccc(NS(C)(=O)=O)cc1)Cc1ccc(cc1)C(C)(C)C |r| Show InChI InChI=1S/C28H41N3O4S2/c1-27(2,3)23-12-8-20(9-13-23)16-22(19-35-25(32)28(4,5)6)18-30-26(36)29-17-21-10-14-24(15-11-21)31-37(7,33)34/h8-15,22,31H,16-19H2,1-7H3,(H2,29,30,36)/t22-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 64 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from rat TRPV1 after 60 mins by competitive binding assay |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017584
(CHEMBL3288616)Show SMILES CC(C)(C)C(=O)OC[C@@H](CNC(=S)NCc1ccc(NS(C)(=O)=O)cc1)Cc1ccccc1 |r| Show InChI InChI=1S/C24H33N3O4S2/c1-24(2,3)22(28)31-17-20(14-18-8-6-5-7-9-18)16-26-23(32)25-15-19-10-12-21(13-11-19)27-33(4,29)30/h5-13,20,27H,14-17H2,1-4H3,(H2,25,26,32)/t20-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 64 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity at rat TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced [45Ca2+] uptake by liquid scintill... |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017590
(CHEMBL3288622)Show SMILES Cc1ccc(C[C@H](CNC(=S)NCc2ccc(NS(C)(=O)=O)cc2)COC(=O)C(C)(C)C)cc1C |r| Show InChI InChI=1S/C26H37N3O4S2/c1-18-7-8-21(13-19(18)2)14-22(17-33-24(30)26(3,4)5)16-28-25(34)27-15-20-9-11-23(12-10-20)29-35(6,31)32/h7-13,22,29H,14-17H2,1-6H3,(H2,27,28,34)/t22-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 67 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity at rat TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced [45Ca2+] uptake by liquid scintill... |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017585
(CHEMBL3288617)Show SMILES CC(C)(C)C(=O)OC[C@H](CNC(=S)NCc1ccc(NS(C)(=O)=O)cc1)Cc1ccccc1 |r| Show InChI InChI=1S/C24H33N3O4S2/c1-24(2,3)22(28)31-17-20(14-18-8-6-5-7-9-18)16-26-23(32)25-15-19-10-12-21(13-11-19)27-33(4,29)30/h5-13,20,27H,14-17H2,1-4H3,(H2,25,26,32)/t20-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 81 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity at rat TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced [45Ca2+] uptake by liquid scintill... |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017595
(CHEMBL3288627)Show SMILES CC(C)(C)C(=O)OC[C@@H](CNC(=S)NCc1ccc(NS(C)(=O)=O)cc1)Cc1ccc(cc1)C(C)(C)C |r| Show InChI InChI=1S/C28H41N3O4S2/c1-27(2,3)23-12-8-20(9-13-23)16-22(19-35-25(32)28(4,5)6)18-30-26(36)29-17-21-10-14-24(15-11-21)31-37(7,33)34/h8-15,22,31H,16-19H2,1-7H3,(H2,29,30,36)/t22-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 86 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity at rat TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced [45Ca2+] uptake by liquid scintill... |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017587
(CHEMBL3288619)Show SMILES C[C@@H](NC(=S)NC[C@@H](COC(=O)C(C)(C)C)Cc1ccccc1)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C25H35N3O4S2/c1-18(21-11-13-22(14-12-21)28-34(5,30)31)27-24(33)26-16-20(15-19-9-7-6-8-10-19)17-32-23(29)25(2,3)4/h6-14,18,20,28H,15-17H2,1-5H3,(H2,26,27,33)/t18-,20+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 89 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity at rat TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced [45Ca2+] uptake by liquid scintill... |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017589
(CHEMBL3288621)Show SMILES C[C@H](NC(=S)NC[C@@H](COC(=O)C(C)(C)C)Cc1ccccc1)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C25H35N3O4S2/c1-18(21-11-13-22(14-12-21)28-34(5,30)31)27-24(33)26-16-20(15-19-9-7-6-8-10-19)17-32-23(29)25(2,3)4/h6-14,18,20,28H,15-17H2,1-5H3,(H2,26,27,33)/t18-,20-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 133 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity at rat TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced [45Ca2+] uptake by liquid scintill... |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017582
(CHEMBL3288632)Show SMILES C[C@@H](NC(=S)N[C@@H](COC(=O)C(C)(C)C)Cc1ccccc1)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C24H33N3O4S2/c1-17(19-11-13-20(14-12-19)27-33(5,29)30)25-23(32)26-21(15-18-9-7-6-8-10-18)16-31-22(28)24(2,3)4/h6-14,17,21,27H,15-16H2,1-5H3,(H2,25,26,32)/t17-,21-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 193 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity at rat TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced [45Ca2+] uptake by liquid scintill... |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017585
(CHEMBL3288617)Show SMILES CC(C)(C)C(=O)OC[C@H](CNC(=S)NCc1ccc(NS(C)(=O)=O)cc1)Cc1ccccc1 |r| Show InChI InChI=1S/C24H33N3O4S2/c1-24(2,3)22(28)31-17-20(14-18-8-6-5-7-9-18)16-26-23(32)25-15-19-10-12-21(13-11-19)27-33(4,29)30/h5-13,20,27H,14-17H2,1-4H3,(H2,25,26,32)/t20-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 236 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from rat TRPV1 after 60 mins by competitive binding assay |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017584
(CHEMBL3288616)Show SMILES CC(C)(C)C(=O)OC[C@@H](CNC(=S)NCc1ccc(NS(C)(=O)=O)cc1)Cc1ccccc1 |r| Show InChI InChI=1S/C24H33N3O4S2/c1-24(2,3)22(28)31-17-20(14-18-8-6-5-7-9-18)16-26-23(32)25-15-19-10-12-21(13-11-19)27-33(4,29)30/h5-13,20,27H,14-17H2,1-4H3,(H2,25,26,32)/t20-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 252 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from rat TRPV1 after 60 mins by competitive binding assay |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017583
(CHEMBL3288633)Show SMILES C[C@@H](NC(=S)N[C@H](COC(=O)C(C)(C)C)Cc1ccccc1)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C24H33N3O4S2/c1-17(19-11-13-20(14-12-19)27-33(5,29)30)25-23(32)26-21(15-18-9-7-6-8-10-18)16-31-22(28)24(2,3)4/h6-14,17,21,27H,15-16H2,1-5H3,(H2,25,26,32)/t17-,21+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 272 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from rat TRPV1 after 60 mins by competitive binding assay |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017583
(CHEMBL3288633)Show SMILES C[C@@H](NC(=S)N[C@H](COC(=O)C(C)(C)C)Cc1ccccc1)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C24H33N3O4S2/c1-17(19-11-13-20(14-12-19)27-33(5,29)30)25-23(32)26-21(15-18-9-7-6-8-10-18)16-31-22(28)24(2,3)4/h6-14,17,21,27H,15-16H2,1-5H3,(H2,25,26,32)/t17-,21+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity at rat TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced [45Ca2+] uptake by liquid scintill... |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017582
(CHEMBL3288632)Show SMILES C[C@@H](NC(=S)N[C@@H](COC(=O)C(C)(C)C)Cc1ccccc1)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C24H33N3O4S2/c1-17(19-11-13-20(14-12-19)27-33(5,29)30)25-23(32)26-21(15-18-9-7-6-8-10-18)16-31-22(28)24(2,3)4/h6-14,17,21,27H,15-16H2,1-5H3,(H2,25,26,32)/t17-,21-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 420 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from rat TRPV1 after 60 mins by competitive binding assay |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017589
(CHEMBL3288621)Show SMILES C[C@H](NC(=S)NC[C@@H](COC(=O)C(C)(C)C)Cc1ccccc1)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C25H35N3O4S2/c1-18(21-11-13-22(14-12-21)28-34(5,30)31)27-24(33)26-16-20(15-19-9-7-6-8-10-19)17-32-23(29)25(2,3)4/h6-14,18,20,28H,15-17H2,1-5H3,(H2,26,27,33)/t18-,20-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 710 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from rat TRPV1 after 60 mins by competitive binding assay |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017588
(CHEMBL3288620)Show SMILES C[C@H](NC(=S)NC[C@H](COC(=O)C(C)(C)C)Cc1ccccc1)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C25H35N3O4S2/c1-18(21-11-13-22(14-12-21)28-34(5,30)31)27-24(33)26-16-20(15-19-9-7-6-8-10-19)17-32-23(29)25(2,3)4/h6-14,18,20,28H,15-17H2,1-5H3,(H2,26,27,33)/t18-,20+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Displacement of [3H]RTX from rat TRPV1 after 60 mins by competitive binding assay |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
Transient receptor potential cation channel subfamily V member 1
(Rattus norvegicus (rat)) | BDBM50017588
(CHEMBL3288620)Show SMILES C[C@H](NC(=S)NC[C@H](COC(=O)C(C)(C)C)Cc1ccccc1)c1ccc(NS(C)(=O)=O)cc1 |r| Show InChI InChI=1S/C25H35N3O4S2/c1-18(21-11-13-22(14-12-21)28-34(5,30)31)27-24(33)26-16-20(15-19-9-7-6-8-10-19)17-32-23(29)25(2,3)4/h6-14,18,20,28H,15-17H2,1-5H3,(H2,26,27,33)/t18-,20+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University
Curated by ChEMBL
| Assay Description
Antagonist activity at rat TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced [45Ca2+] uptake by liquid scintill... |
Bioorg Med Chem Lett 24: 2685-8 (2014)
Article DOI: 10.1016/j.bmcl.2014.04.054
BindingDB Entry DOI: 10.7270/Q26111VT |
More data for this
Ligand-Target Pair | |
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