BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with all data for entry = 50031095
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50197834 (2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-on...) Show SMILES COc1c(O)cc2C(=O)Nc3cc4ccc(O)cc4c1c23 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of CDK2				Bioorg Med Chem Lett 20: 1344-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.018 BindingDB Entry DOI: 10.7270/Q2BZ664X
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Homo sapiens (Human))	BDBM50197834 (2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-on...) Show SMILES COc1c(O)cc2C(=O)Nc3cc4ccc(O)cc4c1c23 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	214	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of CDC2				Bioorg Med Chem Lett 20: 1344-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.018 BindingDB Entry DOI: 10.7270/Q2BZ664X
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 4 (Homo sapiens (Human))	BDBM50197834 (2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-on...) Show SMILES COc1c(O)cc2C(=O)Nc3cc4ccc(O)cc4c1c23 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of CDK4				Bioorg Med Chem Lett 20: 1344-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.018 BindingDB Entry DOI: 10.7270/Q2BZ664X
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50197834 (2,9-dihydroxy-1-methoxydibenzo[cd,f]indol-4(5H)-on...) Show SMILES COc1c(O)cc2C(=O)Nc3cc4ccc(O)cc4c1c23 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of Aurora 2 kinase				Bioorg Med Chem Lett 20: 1344-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.018 BindingDB Entry DOI: 10.7270/Q2BZ664X
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Homo sapiens (Human))	BDBM50306911 (8-((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-hydroxymeth...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Schering Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of CDK2				Bioorg Med Chem Lett 20: 1344-6 (2010) Article DOI: 10.1016/j.bmcl.2010.01.018 BindingDB Entry DOI: 10.7270/Q2BZ664X
Schering Plough Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair