Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50153628 (4-[3-(3-Naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct-2-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro binding affinity for serotonin transporter | Bioorg Med Chem Lett 14: 5281-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.030 BindingDB Entry DOI: 10.7270/Q2F76C1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50153629 (4-[2-(3-Naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct-2-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro binding affinity for serotonin transporter | Bioorg Med Chem Lett 14: 5281-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.030 BindingDB Entry DOI: 10.7270/Q2F76C1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50153621 ((S)-1-[3-(3,4-Dichloro-phenyl)-8-aza-bicyclo[3.2.1...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.380 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro binding affinity for serotonin transporter | Bioorg Med Chem Lett 14: 5281-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.030 BindingDB Entry DOI: 10.7270/Q2F76C1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50153630 (5-[2-(3-Naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct-2-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro binding affinity for serotonin transporter | Bioorg Med Chem Lett 14: 5281-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.030 BindingDB Entry DOI: 10.7270/Q2F76C1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50153627 (8-[2-(3-Naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct-2-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro binding affinity for serotonin transporter | Bioorg Med Chem Lett 14: 5281-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.030 BindingDB Entry DOI: 10.7270/Q2F76C1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50153619 (4-{2-[3-(3,4-Dichloro-phenyl)-8-aza-bicyclo[3.2.1]...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro binding affinity for serotonin transporter | Bioorg Med Chem Lett 14: 5281-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.030 BindingDB Entry DOI: 10.7270/Q2F76C1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50153625 ((S)-1-(1H-Indol-4-yloxy)-3-(3-naphthalen-2-yl-8-az...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro binding affinity for serotonin transporter | Bioorg Med Chem Lett 14: 5281-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.030 BindingDB Entry DOI: 10.7270/Q2F76C1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50153633 (4-{3-[3-(3,4-Dichloro-phenyl)-8-aza-bicyclo[3.2.1]...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.650 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro binding affinity for serotonin transporter | Bioorg Med Chem Lett 14: 5281-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.030 BindingDB Entry DOI: 10.7270/Q2F76C1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50153632 (1H-4-indolyl 3-[3-(1H-3-indolyl)-8-azabicyclo[3.2....) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.650 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro binding affinity for serotonin transporter | Bioorg Med Chem Lett 14: 5281-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.030 BindingDB Entry DOI: 10.7270/Q2F76C1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50153626 (1H-4-indolyl 2-[3-(1H-3-indolyl)-8-azabicyclo[3.2....) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro binding affinity for serotonin transporter | Bioorg Med Chem Lett 14: 5281-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.030 BindingDB Entry DOI: 10.7270/Q2F76C1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50153624 (1-Methyl-4-[2-(3-naphthalen-2-yl-8-aza-bicyclo[3.2...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro binding affinity for serotonin transporter | Bioorg Med Chem Lett 14: 5281-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.030 BindingDB Entry DOI: 10.7270/Q2F76C1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50153631 (8-[2-(Indan-4-yloxy)-ethyl]-3-naphthalen-2-yl-8-az...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro binding affinity for serotonin transporter | Bioorg Med Chem Lett 14: 5281-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.030 BindingDB Entry DOI: 10.7270/Q2F76C1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50153620 (5-{2-[3-(1H-Indol-2-yl)-8-aza-bicyclo[3.2.1]oct-2-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro binding affinity for serotonin transporter | Bioorg Med Chem Lett 14: 5281-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.030 BindingDB Entry DOI: 10.7270/Q2F76C1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50153623 (4-[2-(3-Benzo[b]thiophen-3-yl-8-aza-bicyclo[3.2.1]...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro binding affinity for serotonin transporter | Bioorg Med Chem Lett 14: 5281-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.030 BindingDB Entry DOI: 10.7270/Q2F76C1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50153621 ((S)-1-[3-(3,4-Dichloro-phenyl)-8-aza-bicyclo[3.2.1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 107 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1A receptor expressed in CHO cells was determined using [3H]-8-OH-DPAT radioligand | Bioorg Med Chem Lett 14: 5281-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.030 BindingDB Entry DOI: 10.7270/Q2F76C1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50153626 (1H-4-indolyl 2-[3-(1H-3-indolyl)-8-azabicyclo[3.2....) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 111 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1A receptor expressed in CHO cells was determined using [3H]-8-OH-DPAT radioligand | Bioorg Med Chem Lett 14: 5281-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.030 BindingDB Entry DOI: 10.7270/Q2F76C1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50153625 ((S)-1-(1H-Indol-4-yloxy)-3-(3-naphthalen-2-yl-8-az...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 173 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1A receptor expressed in CHO cells was determined using [3H]-8-OH-DPAT radioligand | Bioorg Med Chem Lett 14: 5281-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.030 BindingDB Entry DOI: 10.7270/Q2F76C1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50153629 (4-[2-(3-Naphthalen-2-yl-8-aza-bicyclo[3.2.1]oct-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 295 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1A receptor expressed in CHO cells was determined using [3H]-8-OH-DPAT radioligand | Bioorg Med Chem Lett 14: 5281-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.030 BindingDB Entry DOI: 10.7270/Q2F76C1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50153620 (5-{2-[3-(1H-Indol-2-yl)-8-aza-bicyclo[3.2.1]oct-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research Curated by ChEMBL | Assay Description In vitro binding affinity for human 5-hydroxytryptamine 1A receptor expressed in CHO cells was determined using [3H]-8-OH-DPAT radioligand | Bioorg Med Chem Lett 14: 5281-4 (2004) Article DOI: 10.1016/j.bmcl.2004.08.030 BindingDB Entry DOI: 10.7270/Q2F76C1B | |||||||||||
More data for this Ligand-Target Pair |