Compile Data Set for Download or QSAR

Found 30 hits Enz. Inhib. hit(s) with all data for entry = 50025181   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM26736 (CHEMBL509860 | LY2183240 | N,N-dimethyl-5-[(4-phen...) Show SMILES CN(C)C(=O)n1nnnc1Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C17H17N5O/c1-21(2)17(23)22-16(18-19-20-22)12-13-8-10-15(11-9-13)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of FAAH mediated [14C]anadamide hydrolysis in rat brain after 30 mins				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50242643 (CHEMBL486427 | N,N-dimethyl-5-((7-phenylheptanamid...) Show SMILES CN(C)C(=O)n1nnc(CNC(=O)CCCCCCc2ccccc2)n1 Show InChI InChI=1S/C18H26N6O2/c1-23(2)18(26)24-21-16(20-22-24)14-19-17(25)13-9-4-3-6-10-15-11-7-5-8-12-15/h5,7-8,11-12H,3-4,6,9-10,13-14H2,1-2H3,(H,19,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of FAAH mediated [14C]anadamide hydrolysis in rat brain after 30 mins				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50242636 (CHEMBL506116 | N,N-Dimethyl-5-(3-phenylpropyl)-1H-...) Show SMILES CN(C)C(=O)n1nnnc1CCCc1ccccc1 Show InChI InChI=1S/C13H17N5O/c1-17(2)13(19)18-12(14-15-16-18)10-6-9-11-7-4-3-5-8-11/h3-5,7-8H,6,9-10H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of FAAH mediated [14C]anadamide hydrolysis in rat brain after 30 mins				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50242645 (CHEMBL486223 | N,N-dimethyl-5-((7-phenyloctanamido...) Show SMILES CN(C)C(=O)n1nnc(CNC(=O)CCCCCCCc2ccccc2)n1 Show InChI InChI=1S/C19H28N6O2/c1-24(2)19(27)25-22-17(21-23-25)15-20-18(26)14-10-5-3-4-7-11-16-12-8-6-9-13-16/h6,8-9,12-13H,3-5,7,10-11,14-15H2,1-2H3,(H,20,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of FAAH mediated [14C]anadamide hydrolysis in rat brain after 30 mins				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50242638 (CHEMBL505359 | N,N-dimethyl-5-(3-phenylpropyl)-2Ht...) Show SMILES CN(C)C(=O)n1nnc(CCCc2ccccc2)n1 Show InChI InChI=1S/C13H17N5O/c1-17(2)13(19)18-15-12(14-16-18)10-6-9-11-7-4-3-5-8-11/h3-5,7-8H,6,9-10H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of FAAH mediated [14C]anadamide hydrolysis in rat brain after 30 mins				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50242637 (CHEMBL504374 | N,N-dimethyl-5-phenethyl-2H-tetrazo...) Show SMILES CN(C)C(=O)n1nnc(CCc2ccccc2)n1 Show InChI InChI=1S/C12H15N5O/c1-16(2)12(18)17-14-11(13-15-17)9-8-10-6-4-3-5-7-10/h3-7H,8-9H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of FAAH mediated [14C]anadamide hydrolysis in rat brain after 30 mins				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50242675 (CHEMBL453043 | N,N-Dimethyl-5-((7-phenylheptanamid...) Show SMILES CN(C)C(=O)n1nnnc1CNC(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C18H26N6O2/c1-23(2)18(26)24-16(20-21-22-24)14-19-17(25)13-9-4-3-6-10-15-11-7-5-8-12-15/h5,7-8,11-12H,3-4,6,9-10,13-14H2,1-2H3,(H,19,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of FAAH mediated [14C]anadamide hydrolysis in rat brain after 30 mins				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50242635 (CHEMBL521191 | N,N-Dimethyl-5-phenethyl-1H-tetrazo...) Show SMILES CN(C)C(=O)n1nnnc1CCc1ccccc1 Show InChI InChI=1S/C12H15N5O/c1-16(2)12(18)17-11(13-14-15-17)9-8-10-6-4-3-5-7-10/h3-7H,8-9H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of FAAH mediated [14C]anadamide hydrolysis in rat brain after 30 mins				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50242642 (5-(Biphenyl-4-ylcarboxamidomethyl)-N,N-dimethyl-2H...) Show SMILES CN(C)C(=O)n1nnc(CNC(=O)c2ccc(cc2)-c2ccccc2)n1 Show InChI InChI=1S/C18H18N6O2/c1-23(2)18(26)24-21-16(20-22-24)12-19-17(25)15-10-8-14(9-11-15)13-6-4-3-5-7-13/h3-11H,12H2,1-2H3,(H,19,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of FAAH mediated [14C]anadamide hydrolysis in rat brain after 30 mins				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50242640 (CHEMBL486039 | N,N-Dimethyl-5-((7-phenyloctanamido...) Show SMILES CN(C)C(=O)n1nnnc1CNC(=O)CCCCCCCc1ccccc1 Show InChI InChI=1S/C19H28N6O2/c1-24(2)19(27)25-17(21-22-23-25)15-20-18(26)14-10-5-3-4-7-11-16-12-8-6-9-13-16/h6,8-9,12-13H,3-5,7,10-11,14-15H2,1-2H3,(H,20,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of FAAH mediated [14C]anadamide hydrolysis in rat brain after 30 mins				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50242641 (5-(biphenyl-3-ylcarboxamidomethyl)-N,N-dimethyl-2H...) Show SMILES CN(C)C(=O)n1nnc(CNC(=O)c2cccc(c2)-c2ccccc2)n1 Show InChI InChI=1S/C18H18N6O2/c1-23(2)18(26)24-21-16(20-22-24)12-19-17(25)15-10-6-9-14(11-15)13-7-4-3-5-8-13/h3-11H,12H2,1-2H3,(H,19,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of FAAH mediated [14C]anadamide hydrolysis in rat brain after 30 mins				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50242639 (5-((4-Azido-3-iodobenzamido)methyl)-N,N-dimethyl-1...) Show SMILES CN(C)C(=O)n1nnnc1CNC(=O)c1ccc(N=[N+]=[N-])c(I)c1 Show InChI InChI=1S/C12H12IN9O2/c1-21(2)12(24)22-10(17-19-20-22)6-15-11(23)7-3-4-9(16-18-14)8(13)5-7/h3-5H,6H2,1-2H3,(H,15,23)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of FAAH mediated [14C]anadamide hydrolysis in rat brain after 30 mins				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50242674 (5-((4-azido-3-iodobenzamido)methyl)-N,N-dimethyl-2...) Show SMILES CN(C)C(=O)n1nnc(CNC(=O)c2ccc(N=[N+]=[N-])c(I)c2)n1 Show InChI InChI=1S/C12H12IN9O2/c1-21(2)12(24)22-18-10(17-20-22)6-15-11(23)7-3-4-9(16-19-14)8(13)5-7/h3-5H,6H2,1-2H3,(H,15,23)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of FAAH mediated [14C]anadamide hydrolysis in rat brain after 30 mins				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50242644 (5-(Biphenyl-3-ylcarboxamidomethyl)-N,N-dimethyl-1H...) Show SMILES CN(C)C(=O)n1nnnc1CNC(=O)c1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C18H18N6O2/c1-23(2)18(26)24-16(20-21-22-24)12-19-17(25)15-10-6-9-14(11-15)13-7-4-3-5-8-13/h3-11H,12H2,1-2H3,(H,19,25)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of FAAH mediated [14C]anadamide hydrolysis in rat brain after 30 mins				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50242634 (5-((biphenyl-4-yl)methyl)-N,N-dimethyl-2H-tetrazol...) Show SMILES CN(C)C(=O)n1nnc(Cc2ccc(cc2)-c2ccccc2)n1 Show InChI InChI=1S/C17H17N5O/c1-21(2)17(23)22-19-16(18-20-22)12-13-8-10-15(11-9-13)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of FAAH mediated [14C]anadamide hydrolysis in rat brain after 30 mins				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Diacylglycerol lipase-alpha (Homo sapiens (Human))	BDBM50242639 (5-((4-Azido-3-iodobenzamido)methyl)-N,N-dimethyl-1...) Show SMILES CN(C)C(=O)n1nnnc1CNC(=O)c1ccc(N=[N+]=[N-])c(I)c1 Show InChI InChI=1S/C12H12IN9O2/c1-21(2)12(24)22-10(17-19-20-22)6-15-11(23)7-3-4-9(16-18-14)8(13)5-7/h3-5H,6H2,1-2H3,(H,15,23)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Diacylglycerol lipase-alpha (Homo sapiens (Human))	BDBM50242675 (CHEMBL453043 | N,N-Dimethyl-5-((7-phenylheptanamid...) Show SMILES CN(C)C(=O)n1nnnc1CNC(=O)CCCCCCc1ccccc1 Show InChI InChI=1S/C18H26N6O2/c1-23(2)18(26)24-16(20-21-22-24)14-19-17(25)13-9-4-3-6-10-15-11-7-5-8-12-15/h5,7-8,11-12H,3-4,6,9-10,13-14H2,1-2H3,(H,19,25)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Diacylglycerol lipase-alpha (Homo sapiens (Human))	BDBM50242644 (5-(Biphenyl-3-ylcarboxamidomethyl)-N,N-dimethyl-1H...) Show SMILES CN(C)C(=O)n1nnnc1CNC(=O)c1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C18H18N6O2/c1-23(2)18(26)24-16(20-21-22-24)12-19-17(25)15-10-6-9-14(11-15)13-7-4-3-5-8-13/h3-11H,12H2,1-2H3,(H,19,25)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Diacylglycerol lipase-alpha (Homo sapiens (Human))	BDBM50242638 (CHEMBL505359 | N,N-dimethyl-5-(3-phenylpropyl)-2Ht...) Show SMILES CN(C)C(=O)n1nnc(CCCc2ccccc2)n1 Show InChI InChI=1S/C13H17N5O/c1-17(2)13(19)18-15-12(14-16-18)10-6-9-11-7-4-3-5-8-11/h3-5,7-8H,6,9-10H2,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Diacylglycerol lipase-alpha (Homo sapiens (Human))	BDBM50242634 (5-((biphenyl-4-yl)methyl)-N,N-dimethyl-2H-tetrazol...) Show SMILES CN(C)C(=O)n1nnc(Cc2ccc(cc2)-c2ccccc2)n1 Show InChI InChI=1S/C17H17N5O/c1-21(2)17(23)22-19-16(18-20-22)12-13-8-10-15(11-9-13)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Diacylglycerol lipase-alpha (Homo sapiens (Human))	BDBM50242640 (CHEMBL486039 | N,N-Dimethyl-5-((7-phenyloctanamido...) Show SMILES CN(C)C(=O)n1nnnc1CNC(=O)CCCCCCCc1ccccc1 Show InChI InChI=1S/C19H28N6O2/c1-24(2)19(27)25-17(21-22-23-25)15-20-18(26)14-10-5-3-4-7-11-16-12-8-6-9-13-16/h6,8-9,12-13H,3-5,7,10-11,14-15H2,1-2H3,(H,20,26)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Diacylglycerol lipase-alpha (Homo sapiens (Human))	BDBM50242637 (CHEMBL504374 | N,N-dimethyl-5-phenethyl-2H-tetrazo...) Show SMILES CN(C)C(=O)n1nnc(CCc2ccccc2)n1 Show InChI InChI=1S/C12H15N5O/c1-16(2)12(18)17-14-11(13-15-17)9-8-10-6-4-3-5-7-10/h3-7H,8-9H2,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Diacylglycerol lipase-alpha (Homo sapiens (Human))	BDBM50242674 (5-((4-azido-3-iodobenzamido)methyl)-N,N-dimethyl-2...) Show SMILES CN(C)C(=O)n1nnc(CNC(=O)c2ccc(N=[N+]=[N-])c(I)c2)n1 Show InChI InChI=1S/C12H12IN9O2/c1-21(2)12(24)22-18-10(17-20-22)6-15-11(23)7-3-4-9(16-19-14)8(13)5-7/h3-5H,6H2,1-2H3,(H,15,23)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Diacylglycerol lipase-alpha (Homo sapiens (Human))	BDBM50242635 (CHEMBL521191 | N,N-Dimethyl-5-phenethyl-1H-tetrazo...) Show SMILES CN(C)C(=O)n1nnnc1CCc1ccccc1 Show InChI InChI=1S/C12H15N5O/c1-16(2)12(18)17-11(13-14-15-17)9-8-10-6-4-3-5-7-10/h3-7H,8-9H2,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Diacylglycerol lipase-alpha (Homo sapiens (Human))	BDBM50242642 (5-(Biphenyl-4-ylcarboxamidomethyl)-N,N-dimethyl-2H...) Show SMILES CN(C)C(=O)n1nnc(CNC(=O)c2ccc(cc2)-c2ccccc2)n1 Show InChI InChI=1S/C18H18N6O2/c1-23(2)18(26)24-21-16(20-22-24)12-19-17(25)15-10-8-14(9-11-15)13-6-4-3-5-7-13/h3-11H,12H2,1-2H3,(H,19,25)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Diacylglycerol lipase-alpha (Homo sapiens (Human))	BDBM50242643 (CHEMBL486427 | N,N-dimethyl-5-((7-phenylheptanamid...) Show SMILES CN(C)C(=O)n1nnc(CNC(=O)CCCCCCc2ccccc2)n1 Show InChI InChI=1S/C18H26N6O2/c1-23(2)18(26)24-21-16(20-22-24)14-19-17(25)13-9-4-3-6-10-15-11-7-5-8-12-15/h5,7-8,11-12H,3-4,6,9-10,13-14H2,1-2H3,(H,19,25)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Diacylglycerol lipase-alpha (Homo sapiens (Human))	BDBM26736 (CHEMBL509860 | LY2183240 | N,N-dimethyl-5-[(4-phen...) Show SMILES CN(C)C(=O)n1nnnc1Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C17H17N5O/c1-21(2)17(23)22-16(18-19-20-22)12-13-8-10-15(11-9-13)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Diacylglycerol lipase-alpha (Homo sapiens (Human))	BDBM50242645 (CHEMBL486223 | N,N-dimethyl-5-((7-phenyloctanamido...) Show SMILES CN(C)C(=O)n1nnc(CNC(=O)CCCCCCCc2ccccc2)n1 Show InChI InChI=1S/C19H28N6O2/c1-24(2)19(27)25-22-17(21-23-25)15-20-18(26)14-10-5-3-4-7-11-16-12-8-6-9-13-16/h6,8-9,12-13H,3-5,7,10-11,14-15H2,1-2H3,(H,20,26)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Diacylglycerol lipase-alpha (Homo sapiens (Human))	BDBM50242636 (CHEMBL506116 | N,N-Dimethyl-5-(3-phenylpropyl)-1H-...) Show SMILES CN(C)C(=O)n1nnnc1CCCc1ccccc1 Show InChI InChI=1S/C13H17N5O/c1-17(2)13(19)18-12(14-15-16-18)10-6-9-11-7-4-3-5-8-11/h3-5,7-8H,6,9-10H2,1-2H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair
Diacylglycerol lipase-alpha (Homo sapiens (Human))	BDBM50242641 (5-(biphenyl-3-ylcarboxamidomethyl)-N,N-dimethyl-2H...) Show SMILES CN(C)C(=O)n1nnc(CNC(=O)c2cccc(c2)-c2ccccc2)n1 Show InChI InChI=1S/C18H18N6O2/c1-23(2)18(26)24-21-16(20-22-24)12-19-17(25)15-10-6-9-14(11-15)13-7-4-3-5-8-13/h3-11H,12H2,1-2H3,(H,19,25)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università di Roma La Sapienza Curated by ChEMBL					Assay Description Inhibition of human recombinant DAGLalpha mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in COS cells after 20 mi...				Eur J Med Chem 43: 62-72 (2008) Article DOI: 10.1016/j.ejmech.2007.02.023 BindingDB Entry DOI: 10.7270/Q2154GS8
					More data for this Ligand-Target Pair