Compile Data Set for Download or QSAR

Found 47 hits Enz. Inhib. hit(s) with all data for entry = 50047083   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50147675 (CHEMBL3764883) Show SMILES O=c1nc(oc2c(cccc12)-c1cccc2c3ccccc3sc12)N1CCOCC1 Show InChI InChI=1S/C24H18N2O3S/c27-23-19-9-3-6-16(21(19)29-24(25-23)26-11-13-28-14-12-26)18-8-4-7-17-15-5-1-2-10-20(15)30-22(17)18/h1-10H,11-14H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of human DNA-PK using EPPLSQEAFADLWKK as substrate by HTRF assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50147674 (CHEMBL3763392) Show SMILES O=c1nc(oc2c(cccc12)-c1cccc2c1oc1ccccc21)N1CCOCC1 Show InChI InChI=1S/C24H18N2O4/c27-23-19-9-4-8-18(22(19)30-24(25-23)26-11-13-28-14-12-26)17-7-3-6-16-15-5-1-2-10-20(15)29-21(16)17/h1-10H,11-14H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	269	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of human DNA-PK using EPPLSQEAFADLWKK as substrate by HTRF assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM12915 (2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...) Show SMILES O=c1cc(oc2c(cccc12)-c1ccccc1)N1CCOCC1 Show InChI InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of human DNA-PK using EPPLSQEAFADLWKK as substrate by HTRF assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50147680 (CHEMBL3763722) Show SMILES Clc1cc(-c2cccc3c4ccccc4sc23)c2oc(nc(=O)c2c1)N1CCOCC1 Show InChI InChI=1S/C24H17ClN2O3S/c25-14-12-18(17-6-3-5-16-15-4-1-2-7-20(15)31-22(16)17)21-19(13-14)23(28)26-24(30-21)27-8-10-29-11-9-27/h1-7,12-13H,8-11H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	564	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of human DNA-PK using EPPLSQEAFADLWKK as substrate by HTRF assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50147683 (CHEMBL3765457) Show SMILES O=c1nc(oc2c(cccc12)-c1cccc2ccccc12)N1CCOCC1 Show InChI InChI=1S/C22H18N2O3/c25-21-19-10-4-9-18(17-8-3-6-15-5-1-2-7-16(15)17)20(19)27-22(23-21)24-11-13-26-14-12-24/h1-10H,11-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	640	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM12915 (2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...) Show SMILES O=c1cc(oc2c(cccc12)-c1ccccc1)N1CCOCC1 Show InChI InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	950	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM12915 (2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...) Show SMILES O=c1cc(oc2c(cccc12)-c1ccccc1)N1CCOCC1 Show InChI InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kgamma (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair				3D Structure (crystal)
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50147676 (CHEMBL3763878) Show SMILES O=c1nc(oc2c(cccc12)-c1cc2ccccc2s1)N1CCOCC1 Show InChI InChI=1S/C20H16N2O3S/c23-19-15-6-3-5-14(17-12-13-4-1-2-7-16(13)26-17)18(15)25-20(21-19)22-8-10-24-11-9-22/h1-7,12H,8-11H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of human DNA-PK using EPPLSQEAFADLWKK as substrate by HTRF assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50147677 (CHEMBL3764880) Show SMILES COc1ccc(cc1)-c1cc(Cl)cc2c1oc(nc2=O)N1CCOCC1 Show InChI InChI=1S/C19H17ClN2O4/c1-24-14-4-2-12(3-5-14)15-10-13(20)11-16-17(15)26-19(21-18(16)23)22-6-8-25-9-7-22/h2-5,10-11H,6-9H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50147684 (CHEMBL3765105) Show SMILES COc1ccc(cc1)-c1cccc2c1oc(nc2=O)N1CCOCC1 Show InChI InChI=1S/C19H18N2O4/c1-23-14-7-5-13(6-8-14)15-3-2-4-16-17(15)25-19(20-18(16)22)21-9-11-24-12-10-21/h2-8H,9-12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50147684 (CHEMBL3765105) Show SMILES COc1ccc(cc1)-c1cccc2c1oc(nc2=O)N1CCOCC1 Show InChI InChI=1S/C19H18N2O4/c1-23-14-7-5-13(6-8-14)15-3-2-4-16-17(15)25-19(20-18(16)22)21-9-11-24-12-10-21/h2-8H,9-12H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM12915 (2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...) Show SMILES O=c1cc(oc2c(cccc12)-c1ccccc1)N1CCOCC1 Show InChI InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kbeta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50147685 (CHEMBL3765574) Show SMILES O=c1nc(oc2c(cccc12)-c1ccsc1)N1CCOCC1 Show InChI InChI=1S/C16H14N2O3S/c19-15-13-3-1-2-12(11-4-9-22-10-11)14(13)21-16(17-15)18-5-7-20-8-6-18/h1-4,9-10H,5-8H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50147688 (CHEMBL3763205) Show SMILES OCc1ccc(cc1)-c1cccc2c1oc(nc2=O)N1CCOCC1 Show InChI InChI=1S/C19H18N2O4/c22-12-13-4-6-14(7-5-13)15-2-1-3-16-17(15)25-19(20-18(16)23)21-8-10-24-11-9-21/h1-7,22H,8-12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kbeta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50147681 (CHEMBL3764119) Show SMILES O=c1nc(oc2c(cccc12)-c1cccs1)N1CCOCC1 Show InChI InChI=1S/C16H14N2O3S/c19-15-12-4-1-3-11(13-5-2-10-22-13)14(12)21-16(17-15)18-6-8-20-9-7-18/h1-5,10H,6-9H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50147685 (CHEMBL3765574) Show SMILES O=c1nc(oc2c(cccc12)-c1ccsc1)N1CCOCC1 Show InChI InChI=1S/C16H14N2O3S/c19-15-13-3-1-2-12(11-4-9-22-10-11)14(13)21-16(17-15)18-5-7-20-8-6-18/h1-4,9-10H,5-8H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kbeta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50147676 (CHEMBL3763878) Show SMILES O=c1nc(oc2c(cccc12)-c1cc2ccccc2s1)N1CCOCC1 Show InChI InChI=1S/C20H16N2O3S/c23-19-15-6-3-5-14(17-12-13-4-1-2-7-16(13)26-17)18(15)25-20(21-19)22-8-10-24-11-9-22/h1-7,12H,8-11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM12915 (2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...) Show SMILES O=c1cc(oc2c(cccc12)-c1ccccc1)N1CCOCC1 Show InChI InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50147681 (CHEMBL3764119) Show SMILES O=c1nc(oc2c(cccc12)-c1cccs1)N1CCOCC1 Show InChI InChI=1S/C16H14N2O3S/c19-15-12-4-1-3-11(13-5-2-10-22-13)14(12)21-16(17-15)18-6-8-20-9-7-18/h1-5,10H,6-9H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50147685 (CHEMBL3765574) Show SMILES O=c1nc(oc2c(cccc12)-c1ccsc1)N1CCOCC1 Show InChI InChI=1S/C16H14N2O3S/c19-15-13-3-1-2-12(11-4-9-22-10-11)14(13)21-16(17-15)18-5-7-20-8-6-18/h1-4,9-10H,5-8H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50147683 (CHEMBL3765457) Show SMILES O=c1nc(oc2c(cccc12)-c1cccc2ccccc12)N1CCOCC1 Show InChI InChI=1S/C22H18N2O3/c25-21-19-10-4-9-18(17-8-3-6-15-5-1-2-7-16(15)17)20(19)27-22(23-21)24-11-13-26-14-12-24/h1-10H,11-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kbeta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50147679 (CHEMBL3765110) Show SMILES Clc1cc(-c2cc3ccccc3s2)c2oc(nc(=O)c2c1)N1CCOCC1 Show InChI InChI=1S/C20H15ClN2O3S/c21-13-10-14(17-9-12-3-1-2-4-16(12)27-17)18-15(11-13)19(24)22-20(26-18)23-5-7-25-8-6-23/h1-4,9-11H,5-8H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of human DNA-PK using EPPLSQEAFADLWKK as substrate by HTRF assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50147675 (CHEMBL3764883) Show SMILES O=c1nc(oc2c(cccc12)-c1cccc2c3ccccc3sc12)N1CCOCC1 Show InChI InChI=1S/C24H18N2O3S/c27-23-19-9-3-6-16(21(19)29-24(25-23)26-11-13-28-14-12-26)18-8-4-7-17-15-5-1-2-10-20(15)30-22(17)18/h1-10H,11-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kbeta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50147678 (CHEMBL3763764) Show SMILES Clc1cc(-c2cccs2)c2oc(nc(=O)c2c1)N1CCOCC1 Show InChI InChI=1S/C16H13ClN2O3S/c17-10-8-11(13-2-1-7-23-13)14-12(9-10)15(20)18-16(22-14)19-3-5-21-6-4-19/h1-2,7-9H,3-6H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of human DNA-PK using EPPLSQEAFADLWKK as substrate by HTRF assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50147674 (CHEMBL3763392) Show SMILES O=c1nc(oc2c(cccc12)-c1cccc2c1oc1ccccc21)N1CCOCC1 Show InChI InChI=1S/C24H18N2O4/c27-23-19-9-4-8-18(22(19)30-24(25-23)26-11-13-28-14-12-26)17-7-3-6-16-15-5-1-2-10-20(15)29-21(16)17/h1-10H,11-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kbeta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50147681 (CHEMBL3764119) Show SMILES O=c1nc(oc2c(cccc12)-c1cccs1)N1CCOCC1 Show InChI InChI=1S/C16H14N2O3S/c19-15-12-4-1-3-11(13-5-2-10-22-13)14(12)21-16(17-15)18-6-8-20-9-7-18/h1-5,10H,6-9H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of human DNA-PK using EPPLSQEAFADLWKK as substrate by HTRF assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50147675 (CHEMBL3764883) Show SMILES O=c1nc(oc2c(cccc12)-c1cccc2c3ccccc3sc12)N1CCOCC1 Show InChI InChI=1S/C24H18N2O3S/c27-23-19-9-3-6-16(21(19)29-24(25-23)26-11-13-28-14-12-26)18-8-4-7-17-15-5-1-2-10-20(15)30-22(17)18/h1-10H,11-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50147686 (CHEMBL3763707) Show SMILES NC(=O)c1ccc(cc1)-c1cccc2c1oc(nc2=O)N1CCOCC1 Show InChI InChI=1S/C19H17N3O4/c20-17(23)13-6-4-12(5-7-13)14-2-1-3-15-16(14)26-19(21-18(15)24)22-8-10-25-11-9-22/h1-7H,8-11H2,(H2,20,23)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of human DNA-PK using EPPLSQEAFADLWKK as substrate by HTRF assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50147688 (CHEMBL3763205) Show SMILES OCc1ccc(cc1)-c1cccc2c1oc(nc2=O)N1CCOCC1 Show InChI InChI=1S/C19H18N2O4/c22-12-13-4-6-14(7-5-13)15-2-1-3-16-17(15)25-19(20-18(16)23)21-8-10-24-11-9-21/h1-7,22H,8-12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50147685 (CHEMBL3765574) Show SMILES O=c1nc(oc2c(cccc12)-c1ccsc1)N1CCOCC1 Show InChI InChI=1S/C16H14N2O3S/c19-15-13-3-1-2-12(11-4-9-22-10-11)14(13)21-16(17-15)18-5-7-20-8-6-18/h1-4,9-10H,5-8H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of human DNA-PK using EPPLSQEAFADLWKK as substrate by HTRF assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50147684 (CHEMBL3765105) Show SMILES COc1ccc(cc1)-c1cccc2c1oc(nc2=O)N1CCOCC1 Show InChI InChI=1S/C19H18N2O4/c1-23-14-7-5-13(6-8-14)15-3-2-4-16-17(15)25-19(20-18(16)22)21-9-11-24-12-10-21/h2-8H,9-12H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of human DNA-PK using EPPLSQEAFADLWKK as substrate by HTRF assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50147689 (CHEMBL3763897) Show SMILES Clc1ccc(cc1)-c1cccc2c1oc(nc2=O)N1CCOCC1 Show InChI InChI=1S/C18H15ClN2O3/c19-13-6-4-12(5-7-13)14-2-1-3-15-16(14)24-18(20-17(15)22)21-8-10-23-11-9-21/h1-7H,8-11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50147686 (CHEMBL3763707) Show SMILES NC(=O)c1ccc(cc1)-c1cccc2c1oc(nc2=O)N1CCOCC1 Show InChI InChI=1S/C19H17N3O4/c20-17(23)13-6-4-12(5-7-13)14-2-1-3-15-16(14)26-19(21-18(15)24)22-8-10-25-11-9-22/h1-7H,8-11H2,(H2,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50147686 (CHEMBL3763707) Show SMILES NC(=O)c1ccc(cc1)-c1cccc2c1oc(nc2=O)N1CCOCC1 Show InChI InChI=1S/C19H17N3O4/c20-17(23)13-6-4-12(5-7-13)14-2-1-3-15-16(14)26-19(21-18(15)24)22-8-10-25-11-9-22/h1-7H,8-11H2,(H2,20,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50147682 (CHEMBL3765523) Show SMILES O=c1nc(oc2c(cccc12)-c1cccnc1)N1CCOCC1 Show InChI InChI=1S/C17H15N3O3/c21-16-14-5-1-4-13(12-3-2-6-18-11-12)15(14)23-17(19-16)20-7-9-22-10-8-20/h1-6,11H,7-10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kbeta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50147678 (CHEMBL3763764) Show SMILES Clc1cc(-c2cccs2)c2oc(nc(=O)c2c1)N1CCOCC1 Show InChI InChI=1S/C16H13ClN2O3S/c17-10-8-11(13-2-1-7-23-13)14-12(9-10)15(20)18-16(22-14)19-3-5-21-6-4-19/h1-2,7-9H,3-6H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50147676 (CHEMBL3763878) Show SMILES O=c1nc(oc2c(cccc12)-c1cc2ccccc2s1)N1CCOCC1 Show InChI InChI=1S/C20H16N2O3S/c23-19-15-6-3-5-14(17-12-13-4-1-2-7-16(13)26-17)18(15)25-20(21-19)22-8-10-24-11-9-22/h1-7,12H,8-11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50147689 (CHEMBL3763897) Show SMILES Clc1ccc(cc1)-c1cccc2c1oc(nc2=O)N1CCOCC1 Show InChI InChI=1S/C18H15ClN2O3/c19-13-6-4-12(5-7-13)14-2-1-3-15-16(14)24-18(20-17(15)22)21-8-10-23-11-9-21/h1-7H,8-11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50147688 (CHEMBL3763205) Show SMILES OCc1ccc(cc1)-c1cccc2c1oc(nc2=O)N1CCOCC1 Show InChI InChI=1S/C19H18N2O4/c22-12-13-4-6-14(7-5-13)15-2-1-3-16-17(15)25-19(20-18(16)23)21-8-10-24-11-9-21/h1-7,22H,8-12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kalpha (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50147687 (CHEMBL3765681) Show SMILES Nc1cccc(c1)-c1cccc2c1oc(nc2=O)N1CCOCC1 Show InChI InChI=1S/C18H17N3O3/c19-13-4-1-3-12(11-13)14-5-2-6-15-16(14)24-18(20-17(15)22)21-7-9-23-10-8-21/h1-6,11H,7-10,19H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kbeta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50147689 (CHEMBL3763897) Show SMILES Clc1ccc(cc1)-c1cccc2c1oc(nc2=O)N1CCOCC1 Show InChI InChI=1S/C18H15ClN2O3/c19-13-6-4-12(5-7-13)14-2-1-3-15-16(14)24-18(20-17(15)22)21-8-10-23-11-9-21/h1-7H,8-11H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of human DNA-PK using EPPLSQEAFADLWKK as substrate by HTRF assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50147674 (CHEMBL3763392) Show SMILES O=c1nc(oc2c(cccc12)-c1cccc2c1oc1ccccc21)N1CCOCC1 Show InChI InChI=1S/C24H18N2O4/c27-23-19-9-4-8-18(22(19)30-24(25-23)26-11-13-28-14-12-26)17-7-3-6-16-15-5-1-2-10-20(15)29-21(16)17/h1-10H,11-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of PI3Kdelta (unknown origin) incubated for 60 mins by kinase-glo luminescence assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50147677 (CHEMBL3764880) Show SMILES COc1ccc(cc1)-c1cc(Cl)cc2c1oc(nc2=O)N1CCOCC1 Show InChI InChI=1S/C19H17ClN2O4/c1-24-14-4-2-12(3-5-14)15-10-13(20)11-16-17(15)26-19(21-18(16)23)22-6-8-25-9-7-22/h2-5,10-11H,6-9H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of human DNA-PK using EPPLSQEAFADLWKK as substrate by HTRF assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50147688 (CHEMBL3763205) Show SMILES OCc1ccc(cc1)-c1cccc2c1oc(nc2=O)N1CCOCC1 Show InChI InChI=1S/C19H18N2O4/c22-12-13-4-6-14(7-5-13)15-2-1-3-16-17(15)25-19(20-18(16)23)21-8-10-24-11-9-21/h1-7,22H,8-12H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of human DNA-PK using EPPLSQEAFADLWKK as substrate by HTRF assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50147683 (CHEMBL3765457) Show SMILES O=c1nc(oc2c(cccc12)-c1cccc2ccccc12)N1CCOCC1 Show InChI InChI=1S/C22H18N2O3/c25-21-19-10-4-9-18(17-8-3-6-15-5-1-2-7-16(15)17)20(19)27-22(23-21)24-11-13-26-14-12-24/h1-10H,11-14H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of human DNA-PK using EPPLSQEAFADLWKK as substrate by HTRF assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50147687 (CHEMBL3765681) Show SMILES Nc1cccc(c1)-c1cccc2c1oc(nc2=O)N1CCOCC1 Show InChI InChI=1S/C18H17N3O3/c19-13-4-1-3-12(11-13)14-5-2-6-15-16(14)24-18(20-17(15)22)21-7-9-23-10-8-21/h1-6,11H,7-10,19H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.35E+4	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of human DNA-PK using EPPLSQEAFADLWKK as substrate by HTRF assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50147682 (CHEMBL3765523) Show SMILES O=c1nc(oc2c(cccc12)-c1cccnc1)N1CCOCC1 Show InChI InChI=1S/C17H15N3O3/c21-16-14-5-1-4-13(12-3-2-6-18-11-12)15(14)23-17(19-16)20-7-9-22-10-8-20/h1-6,11H,7-10H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
La Trobe University Curated by ChEMBL					Assay Description Inhibition of human DNA-PK using EPPLSQEAFADLWKK as substrate by HTRF assay				Eur J Med Chem 110: 326-39 (2016) Article DOI: 10.1016/j.ejmech.2016.01.042 BindingDB Entry DOI: 10.7270/Q2H133V6
					More data for this Ligand-Target Pair