Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proteasome subunit beta type-5 (Homo sapiens (Human)) | BDBM50160869 (CHEMBL3786398) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of chymotrypsin like activity of human erythrocyte-derived 20S proteasome preincubated for 10 mins using Suc-LLVY-AMC as substrate after 6... | Bioorg Med Chem Lett 26: 1958-62 (2016) Article DOI: 10.1016/j.bmcl.2016.03.007 BindingDB Entry DOI: 10.7270/Q2GT5Q2Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit beta type-5 (Homo sapiens (Human)) | BDBM50160867 (CHEMBL499361) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of chymotrypsin like activity of human erythrocyte-derived 20S proteasome preincubated for 10 mins using Suc-LLVY-AMC as substrate after 6... | Bioorg Med Chem Lett 26: 1958-62 (2016) Article DOI: 10.1016/j.bmcl.2016.03.007 BindingDB Entry DOI: 10.7270/Q2GT5Q2Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit beta type-5 (Homo sapiens (Human)) | BDBM50160868 (CHEMBL499504) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of chymotrypsin like activity of human erythrocyte-derived 20S proteasome preincubated for 10 mins using Suc-LLVY-AMC as substrate after 6... | Bioorg Med Chem Lett 26: 1958-62 (2016) Article DOI: 10.1016/j.bmcl.2016.03.007 BindingDB Entry DOI: 10.7270/Q2GT5Q2Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit beta type-5 (Homo sapiens (Human)) | BDBM50069989 ((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of chymotrypsin like activity of human 20S proteasome using ZGlyGlyLeuAMC/SucLeuLeuValTyrAMC as substrate measured every minute for 25 min... | Bioorg Med Chem Lett 26: 1958-62 (2016) Article DOI: 10.1016/j.bmcl.2016.03.007 BindingDB Entry DOI: 10.7270/Q2GT5Q2Q | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Proteasome subunit beta type-5 (Homo sapiens (Human)) | BDBM50160783 (CHEMBL3785681) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.70 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of chymotrypsin like activity of human erythrocyte-derived 20S proteasome preincubated for 10 mins using Suc-LLVY-AMC as substrate after 6... | Bioorg Med Chem Lett 26: 1958-62 (2016) Article DOI: 10.1016/j.bmcl.2016.03.007 BindingDB Entry DOI: 10.7270/Q2GT5Q2Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit beta type-5 (Homo sapiens (Human)) | BDBM50160790 (CHEMBL3786484) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of chymotrypsin like activity of human erythrocyte-derived 20S proteasome preincubated for 10 mins using Suc-LLVY-AMC as substrate after 6... | Bioorg Med Chem Lett 26: 1958-62 (2016) Article DOI: 10.1016/j.bmcl.2016.03.007 BindingDB Entry DOI: 10.7270/Q2GT5Q2Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit beta type-5 (Homo sapiens (Human)) | BDBM50160778 (CHEMBL3785613) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.30 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of chymotrypsin like activity of human erythrocyte-derived 20S proteasome preincubated for 10 mins using Suc-LLVY-AMC as substrate after 6... | Bioorg Med Chem Lett 26: 1958-62 (2016) Article DOI: 10.1016/j.bmcl.2016.03.007 BindingDB Entry DOI: 10.7270/Q2GT5Q2Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit beta type-5 (Homo sapiens (Human)) | BDBM50160781 (CHEMBL3787673) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.90 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of chymotrypsin like activity of human erythrocyte-derived 20S proteasome preincubated for 10 mins using Suc-LLVY-AMC as substrate after 6... | Bioorg Med Chem Lett 26: 1958-62 (2016) Article DOI: 10.1016/j.bmcl.2016.03.007 BindingDB Entry DOI: 10.7270/Q2GT5Q2Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteasome subunit beta type-5 (Homo sapiens (Human)) | BDBM50069989 ((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank PDB Article PubMed | n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of chymotrypsin like activity of human erythrocyte-derived 20S proteasome preincubated for 10 mins using Suc-LLVY-AMC as substrate after 6... | Bioorg Med Chem Lett 26: 1958-62 (2016) Article DOI: 10.1016/j.bmcl.2016.03.007 BindingDB Entry DOI: 10.7270/Q2GT5Q2Q | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Proteasome subunit beta type-5 (Homo sapiens (Human)) | BDBM50160780 (CHEMBL3785317) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.5 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of chymotrypsin like activity of human erythrocyte-derived 20S proteasome preincubated for 10 mins using Suc-LLVY-AMC as substrate after 6... | Bioorg Med Chem Lett 26: 1958-62 (2016) Article DOI: 10.1016/j.bmcl.2016.03.007 BindingDB Entry DOI: 10.7270/Q2GT5Q2Q | |||||||||||
More data for this Ligand-Target Pair |