Found 101 hits Enz. Inhib. hit(s) with all data for entry = 50035322 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135615
(4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)Show SMILES CN(C)CCOCCOC(=O)c1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C15H21N5O7S3/c1-20(2)7-8-26-9-10-27-13(21)11-3-5-12(6-4-11)30(24,25)19-14-17-18-15(28-14)29(16,22)23/h3-6H,7-10H2,1-2H3,(H,17,19)(H2,16,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM11636
(CHEMBL309431 | N-[2-(diethylamino)ethyl]-4-[(5-sul...)Show SMILES CCN(CC)CCNC(=O)c1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C15H22N6O5S3/c1-3-21(4-2)10-9-17-13(22)11-5-7-12(8-6-11)29(25,26)20-14-18-19-15(27-14)28(16,23)24/h5-8H,3-4,9-10H2,1-2H3,(H,17,22)(H,18,20)(H2,16,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135629
(4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)Show SMILES CC(CN(C)C)OC(=O)c1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C14H19N5O6S3/c1-9(8-19(2)3)25-12(20)10-4-6-11(7-5-10)28(23,24)18-13-16-17-14(26-13)27(15,21)22/h4-7,9H,8H2,1-3H3,(H,16,18)(H2,15,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135609
(4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)Show SMILES CN(C)CCOC(=O)c1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C13H17N5O6S3/c1-18(2)7-8-24-11(19)9-3-5-10(6-4-9)27(22,23)17-12-15-16-13(25-12)26(14,20)21/h3-6H,7-8H2,1-2H3,(H,15,17)(H2,14,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135617
(3-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)Show SMILES CN(C)CCOCCOC(=O)c1cccc(c1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C15H21N5O7S3/c1-20(2)6-7-26-8-9-27-13(21)11-4-3-5-12(10-11)30(24,25)19-14-17-18-15(28-14)29(16,22)23/h3-5,10H,6-9H2,1-2H3,(H,17,19)(H2,16,22,23) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135606
(CHEMBL99337 | N-(2-Diethylamino-ethyl)-4-[3-methyl...)Show SMILES CCN(CC)CCNC(=O)c1ccc(cc1)S(=O)(=O)\N=c1\sc(nn1C)S(N)(=O)=O Show InChI InChI=1S/C16H24N6O5S3/c1-4-22(5-2)11-10-18-14(23)12-6-8-13(9-7-12)30(26,27)20-15-21(3)19-16(28-15)29(17,24)25/h6-9H,4-5,10-11H2,1-3H3,(H,18,23)(H2,17,24,25)/b20-15+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135623
(4-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-...)Show SMILES CN(C)CCOCCOC(=O)c1ccc(cc1)S(=O)(=O)\N=c1\sc(nn1C)S(N)(=O)=O Show InChI InChI=1S/C16H23N5O7S3/c1-20(2)8-9-27-10-11-28-14(22)12-4-6-13(7-5-12)31(25,26)19-15-21(3)18-16(29-15)30(17,23)24/h4-7H,8-11H2,1-3H3,(H2,17,23,24)/b19-15+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135610
(CHEMBL100329 | N-(2-Diethylamino-ethyl)-3-(5-sulfa...)Show SMILES CCN(CC)CCNC(=O)c1cccc(c1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C15H22N6O5S3/c1-3-21(4-2)9-8-17-13(22)11-6-5-7-12(10-11)29(25,26)20-14-18-19-15(27-14)28(16,23)24/h5-7,10H,3-4,8-9H2,1-2H3,(H,17,22)(H,18,20)(H2,16,23,24) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135603
(4-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-...)Show SMILES CC(CN(C)C)OC(=O)c1ccc(cc1)S(=O)(=O)\N=c1\sc(nn1C)S(N)(=O)=O Show InChI InChI=1S/C15H21N5O6S3/c1-10(9-19(2)3)26-13(21)11-5-7-12(8-6-11)29(24,25)18-14-20(4)17-15(27-14)28(16,22)23/h5-8,10H,9H2,1-4H3,(H2,16,22,23)/b18-14+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135619
(CHEMBL317383 | N-(2-Diethylamino-ethyl)-3-[3-methy...)Show SMILES CCN(CC)CCNC(=O)c1cccc(c1)S(=O)(=O)\N=c1\sc(nn1C)S(N)(=O)=O Show InChI InChI=1S/C16H24N6O5S3/c1-4-22(5-2)10-9-18-14(23)12-7-6-8-13(11-12)30(26,27)20-15-21(3)19-16(28-15)29(17,24)25/h6-8,11H,4-5,9-10H2,1-3H3,(H,18,23)(H2,17,24,25)/b20-15+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135620
(3-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)Show SMILES CC(CN(C)C)OC(=O)c1cccc(c1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C14H19N5O6S3/c1-9(8-19(2)3)25-12(20)10-5-4-6-11(7-10)28(23,24)18-13-16-17-14(26-13)27(15,21)22/h4-7,9H,8H2,1-3H3,(H,16,18)(H2,15,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135613
(3-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-...)Show SMILES CN(C)CCOCCOC(=O)c1cccc(c1)S(=O)(=O)\N=c1\sc(nn1C)S(N)(=O)=O Show InChI InChI=1S/C16H23N5O7S3/c1-20(2)7-8-27-9-10-28-14(22)12-5-4-6-13(11-12)31(25,26)19-15-21(3)18-16(29-15)30(17,23)24/h4-6,11H,7-10H2,1-3H3,(H2,17,23,24)/b19-15+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135626
(3-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)Show SMILES CN(C)CCOC(=O)c1cccc(c1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C13H17N5O6S3/c1-18(2)6-7-24-11(19)9-4-3-5-10(8-9)27(22,23)17-12-15-16-13(25-12)26(14,20)21/h3-5,8H,6-7H2,1-2H3,(H,15,17)(H2,14,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135611
(3-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-...)Show SMILES CC(CN(C)C)OC(=O)c1cccc(c1)S(=O)(=O)\N=c1\sc(nn1C)S(N)(=O)=O Show InChI InChI=1S/C15H21N5O6S3/c1-10(9-19(2)3)26-13(21)11-6-5-7-12(8-11)29(24,25)18-14-20(4)17-15(27-14)28(16,22)23/h5-8,10H,9H2,1-4H3,(H2,16,22,23)/b18-14+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135622
(4-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-...)Show SMILES CN(C)CCOC(=O)c1ccc(cc1)S(=O)(=O)\N=c1\sc(nn1C)S(N)(=O)=O Show InChI InChI=1S/C14H19N5O6S3/c1-18(2)8-9-25-12(20)10-4-6-11(7-5-10)28(23,24)17-13-19(3)16-14(26-13)27(15,21)22/h4-7H,8-9H2,1-3H3,(H2,15,21,22)/b17-13+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135614
(4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)Show SMILES COCCOC(=O)c1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C12H14N4O7S3/c1-22-6-7-23-10(17)8-2-4-9(5-3-8)26(20,21)16-11-14-15-12(24-11)25(13,18)19/h2-5H,6-7H2,1H3,(H,14,16)(H2,13,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135616
(4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)c2ccc(cc2)C(=O)OCCO)s1 Show InChI InChI=1S/C11H12N4O7S3/c12-24(18,19)11-14-13-10(23-11)15-25(20,21)8-3-1-7(2-4-8)9(17)22-6-5-16/h1-4,16H,5-6H2,(H,13,15)(H2,12,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135605
(3-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)Show SMILES COCCOC(=O)c1cccc(c1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C12H14N4O7S3/c1-22-5-6-23-10(17)8-3-2-4-9(7-8)26(20,21)16-11-14-15-12(24-11)25(13,18)19/h2-4,7H,5-6H2,1H3,(H,14,16)(H2,13,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135627
(3-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-...)Show SMILES CN(C)CCOC(=O)c1cccc(c1)S(=O)(=O)\N=c1\sc(nn1C)S(N)(=O)=O Show InChI InChI=1S/C14H19N5O6S3/c1-18(2)7-8-25-12(20)10-5-4-6-11(9-10)28(23,24)17-13-19(3)16-14(26-13)27(15,21)22/h4-6,9H,7-8H2,1-3H3,(H2,15,21,22)/b17-13+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10885
((4R)-4-(ethylamino)-2-(3-methoxypropyl)-1,1-dioxo-...)Show SMILES CCN[C@H]1CN(CCCOC)S(=O)(=O)c2sc(cc12)S(N)(=O)=O |r| Show InChI InChI=1S/C12H21N3O5S3/c1-3-14-10-8-15(5-4-6-20-2)23(18,19)12-9(10)7-11(21-12)22(13,16)17/h7,10,14H,3-6,8H2,1-2H3,(H2,13,16,17)/t10-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PubMed
| 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135625
(3-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)c2cccc(c2)C(=O)OCCO)s1 Show InChI InChI=1S/C11H12N4O7S3/c12-24(18,19)11-14-13-10(23-11)15-25(20,21)8-3-1-2-7(6-8)9(17)22-5-4-16/h1-3,6,16H,4-5H2,(H,13,15)(H2,12,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135628
(4-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-...)Show SMILES COCCOC(=O)c1ccc(cc1)S(=O)(=O)\N=c1\sc(nn1C)S(N)(=O)=O Show InChI InChI=1S/C13H16N4O7S3/c1-17-12(25-13(15-17)26(14,19)20)16-27(21,22)10-5-3-9(4-6-10)11(18)24-8-7-23-2/h3-6H,7-8H2,1-2H3,(H2,14,19,20)/b16-12+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135607
(3-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-...)Show SMILES COCCOC(=O)c1cccc(c1)S(=O)(=O)\N=c1\sc(nn1C)S(N)(=O)=O Show InChI InChI=1S/C13H16N4O7S3/c1-17-12(25-13(15-17)26(14,19)20)16-27(21,22)10-5-3-4-9(8-10)11(18)24-7-6-23-2/h3-5,8H,6-7H2,1-2H3,(H2,14,19,20)/b16-12+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135604
(4-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-...)Show SMILES Cn1nc(s\c1=N\S(=O)(=O)c1ccc(cc1)C(=O)OCCO)S(N)(=O)=O Show InChI InChI=1S/C12H14N4O7S3/c1-16-11(24-12(14-16)25(13,19)20)15-26(21,22)9-4-2-8(3-5-9)10(18)23-7-6-17/h2-5,17H,6-7H2,1H3,(H2,13,19,20)/b15-11+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135621
(4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)c2ccc(cc2)C(O)=O)s1 Show InChI InChI=1S/C9H8N4O6S3/c10-21(16,17)9-12-11-8(20-9)13-22(18,19)6-3-1-5(2-4-6)7(14)15/h1-4H,(H,11,13)(H,14,15)(H2,10,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | 3D Structure (docked) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135618
(3-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)c2cccc(c2)C(O)=O)s1 Show InChI InChI=1S/C9H8N4O6S3/c10-21(16,17)9-12-11-8(20-9)13-22(18,19)6-3-1-2-5(4-6)7(14)15/h1-4H,(H,11,13)(H,14,15)(H2,10,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135608
(3-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-...)Show SMILES Cn1nc(s\c1=N\S(=O)(=O)c1cccc(c1)C(=O)OCCO)S(N)(=O)=O Show InChI InChI=1S/C12H14N4O7S3/c1-16-11(24-12(14-16)25(13,19)20)15-26(21,22)9-4-2-3-8(7-9)10(18)23-6-5-17/h2-4,7,17H,5-6H2,1H3,(H2,13,19,20)/b15-11+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135612
(4-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-...)Show SMILES Cn1nc(s\c1=N\S(=O)(=O)c1ccc(cc1)C(O)=O)S(N)(=O)=O Show InChI InChI=1S/C10H10N4O6S3/c1-14-9(21-10(12-14)22(11,17)18)13-23(19,20)7-4-2-6(3-5-7)8(15)16/h2-5H,1H3,(H,15,16)(H2,11,17,18)/b13-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50135624
(3-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-...)Show SMILES Cn1nc(s\c1=N\S(=O)(=O)c1cccc(c1)C(O)=O)S(N)(=O)=O Show InChI InChI=1S/C10H10N4O6S3/c1-14-9(21-10(12-14)22(11,17)18)13-23(19,20)7-4-2-3-6(5-7)8(15)16/h2-5H,1H3,(H,15,16)(H2,11,17,18)/b13-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 5.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50135617
(3-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)Show SMILES CN(C)CCOCCOC(=O)c1cccc(c1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C15H21N5O7S3/c1-20(2)6-7-26-8-9-27-13(21)11-4-3-5-12(10-11)30(24,25)19-14-17-18-15(28-14)29(16,22)23/h3-5,10H,6-9H2,1-2H3,(H,17,19)(H2,16,22,23) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against Carbonic anhydrase IV isolated from bovine lung |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50135615
(4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)Show SMILES CN(C)CCOCCOC(=O)c1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C15H21N5O7S3/c1-20(2)7-8-26-9-10-27-13(21)11-3-5-12(6-4-11)30(24,25)19-14-17-18-15(28-14)29(16,22)23/h3-6H,7-10H2,1-2H3,(H,17,19)(H2,16,22,23) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against Carbonic anhydrase IV isolated from bovine lung |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank MMDB PDB PubMed
| 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50135610
(CHEMBL100329 | N-(2-Diethylamino-ethyl)-3-(5-sulfa...)Show SMILES CCN(CC)CCNC(=O)c1cccc(c1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C15H22N6O5S3/c1-3-21(4-2)9-8-17-13(22)11-6-5-7-12(10-11)29(25,26)20-14-18-19-15(27-14)28(16,23)24/h5-7,10H,3-4,8-9H2,1-2H3,(H,17,22)(H,18,20)(H2,16,23,24) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against Carbonic anhydrase IV isolated from bovine lung |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50135619
(CHEMBL317383 | N-(2-Diethylamino-ethyl)-3-[3-methy...)Show SMILES CCN(CC)CCNC(=O)c1cccc(c1)S(=O)(=O)\N=c1\sc(nn1C)S(N)(=O)=O Show InChI InChI=1S/C16H24N6O5S3/c1-4-22(5-2)10-9-18-14(23)12-7-6-8-13(11-12)30(26,27)20-15-21(3)19-16(28-15)29(17,24)25/h6-8,11H,4-5,9-10H2,1-3H3,(H,18,23)(H2,17,24,25)/b20-15+ | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against Carbonic anhydrase IV isolated from bovine lung |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50135626
(3-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)Show SMILES CN(C)CCOC(=O)c1cccc(c1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C13H17N5O6S3/c1-18(2)6-7-24-11(19)9-4-3-5-10(8-9)27(22,23)17-12-15-16-13(25-12)26(14,20)21/h3-5,8H,6-7H2,1-2H3,(H,15,17)(H2,14,20,21) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against Carbonic anhydrase IV isolated from bovine lung |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50135606
(CHEMBL99337 | N-(2-Diethylamino-ethyl)-4-[3-methyl...)Show SMILES CCN(CC)CCNC(=O)c1ccc(cc1)S(=O)(=O)\N=c1\sc(nn1C)S(N)(=O)=O Show InChI InChI=1S/C16H24N6O5S3/c1-4-22(5-2)11-10-18-14(23)12-6-8-13(9-7-12)30(26,27)20-15-21(3)19-16(28-15)29(17,24)25/h6-9H,4-5,10-11H2,1-3H3,(H,18,23)(H2,17,24,25)/b20-15+ | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against Carbonic anhydrase IV isolated from bovine lung |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50135613
(3-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-...)Show SMILES CN(C)CCOCCOC(=O)c1cccc(c1)S(=O)(=O)\N=c1\sc(nn1C)S(N)(=O)=O Show InChI InChI=1S/C16H23N5O7S3/c1-20(2)7-8-27-9-10-28-14(22)12-5-4-6-13(11-12)31(25,26)19-15-21(3)18-16(29-15)30(17,23)24/h4-6,11H,7-10H2,1-3H3,(H2,17,23,24)/b19-15+ | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against Carbonic anhydrase IV isolated from bovine lung |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50135620
(3-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)Show SMILES CC(CN(C)C)OC(=O)c1cccc(c1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C14H19N5O6S3/c1-9(8-19(2)3)25-12(20)10-5-4-6-11(7-10)28(23,24)18-13-16-17-14(26-13)27(15,21)22/h4-7,9H,8H2,1-3H3,(H,16,18)(H2,15,21,22) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against Carbonic anhydrase IV isolated from bovine lung |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50135605
(3-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)Show SMILES COCCOC(=O)c1cccc(c1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C12H14N4O7S3/c1-22-5-6-23-10(17)8-3-2-4-9(7-8)26(20,21)16-11-14-15-12(24-11)25(13,18)19/h2-4,7H,5-6H2,1H3,(H,14,16)(H2,13,18,19) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against Carbonic anhydrase IV isolated from bovine lung |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10882
(6-ethoxy-1,3-benzothiazole-2-sulfonamide | CHEMBL1...)Show InChI InChI=1S/C9H10N2O3S2/c1-2-14-6-3-4-7-8(5-6)15-9(11-7)16(10,12)13/h3-5H,2H2,1H3,(H2,10,12,13) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| MMDB PDB PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50135625
(3-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)Show SMILES NS(=O)(=O)c1nnc(NS(=O)(=O)c2cccc(c2)C(=O)OCCO)s1 Show InChI InChI=1S/C11H12N4O7S3/c12-24(18,19)11-14-13-10(23-11)15-25(20,21)8-3-1-2-7(6-8)9(17)22-5-4-16/h1-3,6,16H,4-5H2,(H,13,15)(H2,12,18,19) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against Carbonic anhydrase IV isolated from bovine lung |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM11636
(CHEMBL309431 | N-[2-(diethylamino)ethyl]-4-[(5-sul...)Show SMILES CCN(CC)CCNC(=O)c1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C15H22N6O5S3/c1-3-21(4-2)10-9-17-13(22)11-5-7-12(8-6-11)29(25,26)20-14-18-19-15(27-14)28(16,23)24/h5-8H,3-4,9-10H2,1-2H3,(H,17,22)(H,18,20)(H2,16,23,24) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against Carbonic anhydrase IV isolated from bovine lung |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10886
(2-N-benzene-1,3,4-thiadiazole-2,5-disulfonamide | ...)Show InChI InChI=1S/C8H8N4O4S3/c9-18(13,14)8-11-10-7(17-8)12-19(15,16)6-4-2-1-3-5-6/h1-5H,(H,10,12)(H2,9,13,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| MMDB PDB PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10884
((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)Show SMILES CCN[C@H]1C[C@H](C)S(=O)(=O)c2sc(cc12)S(N)(=O)=O |r| Show InChI InChI=1S/C10H16N2O4S3/c1-3-12-8-4-6(2)18(13,14)10-7(8)5-9(17-10)19(11,15)16/h5-6,8,12H,3-4H2,1-2H3,(H2,11,15,16)/t6-,8-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10881
(CHEMBL288100 | MZA3 | Methazolamide | Methazolamid...)Show InChI InChI=1S/C5H8N4O3S2/c1-3(10)7-4-9(2)8-5(13-4)14(6,11)12/h1-2H3,(H2,6,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PDB PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against human carbonic anhydrase II |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50135623
(4-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-...)Show SMILES CN(C)CCOCCOC(=O)c1ccc(cc1)S(=O)(=O)\N=c1\sc(nn1C)S(N)(=O)=O Show InChI InChI=1S/C16H23N5O7S3/c1-20(2)8-9-27-10-11-28-14(22)12-4-6-13(7-5-12)31(25,26)19-15-21(3)18-16(29-15)30(17,23)24/h4-7H,8-11H2,1-3H3,(H2,17,23,24)/b19-15+ | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against Carbonic anhydrase IV isolated from bovine lung |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50135607
(3-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-...)Show SMILES COCCOC(=O)c1cccc(c1)S(=O)(=O)\N=c1\sc(nn1C)S(N)(=O)=O Show InChI InChI=1S/C13H16N4O7S3/c1-17-12(25-13(15-17)26(14,19)20)16-27(21,22)10-5-3-4-9(8-10)11(18)24-7-6-23-2/h3-5,8H,6-7H2,1-2H3,(H2,14,19,20)/b16-12+ | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against Carbonic anhydrase IV isolated from bovine lung |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50135608
(3-[3-Methyl-5-sulfamoyl-3H-[1,3,4]thiadiazol-(2E)-...)Show SMILES Cn1nc(s\c1=N\S(=O)(=O)c1cccc(c1)C(=O)OCCO)S(N)(=O)=O Show InChI InChI=1S/C12H14N4O7S3/c1-16-11(24-12(14-16)25(13,19)20)15-26(21,22)9-4-2-3-8(7-9)10(18)23-6-5-17/h2-4,7,17H,5-6H2,1H3,(H2,13,19,20)/b15-11+ | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against Carbonic anhydrase IV isolated from bovine lung |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50135609
(4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)Show SMILES CN(C)CCOC(=O)c1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C13H17N5O6S3/c1-18(2)7-8-24-11(19)9-3-5-10(6-4-9)27(22,23)17-12-15-16-13(25-12)26(14,20)21/h3-6H,7-8H2,1-2H3,(H,15,17)(H2,14,20,21) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against Carbonic anhydrase IV isolated from bovine lung |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 4
(Bos taurus (bovine)) | BDBM50135629
(4-(5-Sulfamoyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-be...)Show SMILES CC(CN(C)C)OC(=O)c1ccc(cc1)S(=O)(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C14H19N5O6S3/c1-9(8-19(2)3)25-12(20)10-4-6-11(7-5-10)28(23,24)18-13-16-17-14(26-13)27(15,21)22/h4-7,9H,8H2,1-3H3,(H,16,18)(H2,15,21,22) | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi
Curated by ChEMBL
| Assay Description Inhibitory activity against Carbonic anhydrase IV isolated from bovine lung |
Bioorg Med Chem Lett 13: 2867-73 (2003)
BindingDB Entry DOI: 10.7270/Q2BR8SQ8 |
More data for this Ligand-Target Pair | |