Compile Data Set for Download or QSAR

Found 192 hits Enz. Inhib. hit(s) with all data for entry = 50049293   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50238272 (CHEMBL4072731) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4ccc(N5CCOCC5)c(C)c4)cc3)c12 Show InChI InChI=1S/C25H26N6O2/c1-16-15-20(7-8-22(16)31-11-13-33-14-12-31)28-25(32)27-19-5-3-18(4-6-19)21-9-10-26-24-23(21)17(2)29-30-24/h3-10,15H,11-14H2,1-2H3,(H,26,29,30)(H2,27,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human His-tagged PDGFRbeta (558 to 1106 residues) expressed in baculovirus by ELISA				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238298 (CHEMBL4074755) Show SMILES CCCCCCNC(=O)Nc1ccc(cc1)-c1ccnc2[nH]nc(C)c12 Show InChI InChI=1S/C20H25N5O/c1-3-4-5-6-12-22-20(26)23-16-9-7-15(8-10-16)17-11-13-21-19-18(17)14(2)24-25-19/h7-11,13H,3-6,12H2,1-2H3,(H,21,24,25)(H2,22,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description In vitro inhibitory activity against Angiotensin I converting enzyme				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238307 (CHEMBL4101428) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)NCCCc4ccccc4)cc3)c12 Show InChI InChI=1S/C23H23N5O/c1-16-21-20(13-15-24-22(21)28-27-16)18-9-11-19(12-10-18)26-23(29)25-14-5-8-17-6-3-2-4-7-17/h2-4,6-7,9-13,15H,5,8,14H2,1H3,(H,24,27,28)(H2,25,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238268 (CHEMBL4091975) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cnc5ccccc5c4)cc3)c12 Show InChI InChI=1S/C23H18N6O/c1-14-21-19(10-11-24-22(21)29-28-14)15-6-8-17(9-7-15)26-23(30)27-18-12-16-4-2-3-5-20(16)25-13-18/h2-13H,1H3,(H,24,28,29)(H2,26,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50238272 (CHEMBL4072731) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4ccc(N5CCOCC5)c(C)c4)cc3)c12 Show InChI InChI=1S/C25H26N6O2/c1-16-15-20(7-8-22(16)31-11-13-33-14-12-31)28-25(32)27-19-5-3-18(4-6-19)21-9-10-26-24-23(21)17(2)29-30-24/h3-10,15H,11-14H2,1-2H3,(H,26,29,30)(H2,27,28,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human His-tagged FLT3 (564 to 958 residues) expressed in baculovirus by ELISA				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238308 (CHEMBL4103605) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)c12 Show InChI InChI=1S/C21H19N5O/c1-13-4-3-5-17(12-13)24-21(27)23-16-8-6-15(7-9-16)18-10-11-22-20-19(18)14(2)25-26-20/h3-12H,1-2H3,(H,22,25,26)(H2,23,24,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238289 (CHEMBL4083050) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2ccnc3[nH]nc(CO)c23)c1 Show InChI InChI=1S/C21H19N5O2/c1-13-3-2-4-16(11-13)24-21(28)23-15-7-5-14(6-8-15)17-9-10-22-20-19(17)18(12-27)25-26-20/h2-11,27H,12H2,1H3,(H,22,25,26)(H2,23,24,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238272 (CHEMBL4072731) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4ccc(N5CCOCC5)c(C)c4)cc3)c12 Show InChI InChI=1S/C25H26N6O2/c1-16-15-20(7-8-22(16)31-11-13-33-14-12-31)28-25(32)27-19-5-3-18(4-6-19)21-9-10-26-24-23(21)17(2)29-30-24/h3-10,15H,11-14H2,1-2H3,(H,26,29,30)(H2,27,28,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description In vitro inhibitory activity against Angiotensin I converting enzyme				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238290 (CHEMBL4064941) Show SMILES CN(C)c1cccc(NC(=O)Nc2ccc(cc2)-c2ccnc3[nH]nc(C)c23)c1 Show InChI InChI=1S/C22H22N6O/c1-14-20-19(11-12-23-21(20)27-26-14)15-7-9-16(10-8-15)24-22(29)25-17-5-4-6-18(13-17)28(2)3/h4-13H,1-3H3,(H,23,26,27)(H2,24,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238294 (CHEMBL4063380) Show SMILES CCCCCNC(=O)Nc1ccc(cc1)-c1ccnc2[nH]nc(C)c12 Show InChI InChI=1S/C19H23N5O/c1-3-4-5-11-21-19(25)22-15-8-6-14(7-9-15)16-10-12-20-18-17(16)13(2)23-24-18/h6-10,12H,3-5,11H2,1-2H3,(H,20,23,24)(H2,21,22,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238295 (CHEMBL4099718) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cccc5ccccc45)cc3)c12 Show InChI InChI=1S/C24H19N5O/c1-15-22-20(13-14-25-23(22)29-28-15)17-9-11-18(12-10-17)26-24(30)27-21-8-4-6-16-5-2-3-7-19(16)21/h2-14H,1H3,(H,25,28,29)(H2,26,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238300 (CHEMBL4059958) Show SMILES CCc1cccc(NC(=O)Nc2ccc(cc2)-c2ccnc3[nH]nc(CO)c23)c1 Show InChI InChI=1S/C22H21N5O2/c1-2-14-4-3-5-17(12-14)25-22(29)24-16-8-6-15(7-9-16)18-10-11-23-21-20(18)19(13-28)26-27-21/h3-12,28H,2,13H2,1H3,(H,23,26,27)(H2,24,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238310 (CHEMBL4100492) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)NCCc4ccccc4)cc3)c12 Show InChI InChI=1S/C22H21N5O/c1-15-20-19(12-14-23-21(20)27-26-15)17-7-9-18(10-8-17)25-22(28)24-13-11-16-5-3-2-4-6-16/h2-10,12,14H,11,13H2,1H3,(H,23,26,27)(H2,24,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238299 (CHEMBL4074518) Show SMILES CCc1cccc(NC(=O)Nc2ccc(cc2)-c2ccnc3[nH]nc(C)c23)c1 Show InChI InChI=1S/C22H21N5O/c1-3-15-5-4-6-18(13-15)25-22(28)24-17-9-7-16(8-10-17)19-11-12-23-21-20(19)14(2)26-27-21/h4-13H,3H2,1-2H3,(H,23,26,27)(H2,24,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM13530 (4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1 Show InChI InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238281 (CHEMBL4074745) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)NCCCCc4ccccc4)cc3)c12 Show InChI InChI=1S/C24H25N5O/c1-17-22-21(14-16-25-23(22)29-28-17)19-10-12-20(13-11-19)27-24(30)26-15-6-5-9-18-7-3-2-4-8-18/h2-4,7-8,10-14,16H,5-6,9,15H2,1H3,(H,25,28,29)(H2,26,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238311 (CHEMBL4066302) Show SMILES CN1CCN(CC1)c1ccc(NC(=O)Nc2ccc(cc2)-c2ccnc3[nH]nc(C)c23)cc1C Show InChI InChI=1S/C26H29N7O/c1-17-16-21(8-9-23(17)33-14-12-32(3)13-15-33)29-26(34)28-20-6-4-19(5-7-20)22-10-11-27-25-24(22)18(2)30-31-25/h4-11,16H,12-15H2,1-3H3,(H,27,30,31)(H2,28,29,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238272 (CHEMBL4072731) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4ccc(N5CCOCC5)c(C)c4)cc3)c12 Show InChI InChI=1S/C25H26N6O2/c1-16-15-20(7-8-22(16)31-11-13-33-14-12-31)28-25(32)27-19-5-3-18(4-6-19)21-9-10-26-24-23(21)17(2)29-30-24/h3-10,15H,11-14H2,1-2H3,(H,26,29,30)(H2,27,28,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238328 (CHEMBL4063368) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)NC4Cc5ccccc5C4)cc3)c12 Show InChI InChI=1S/C23H21N5O/c1-14-21-20(10-11-24-22(21)28-27-14)15-6-8-18(9-7-15)25-23(29)26-19-12-16-4-2-3-5-17(16)13-19/h2-11,19H,12-13H2,1H3,(H,24,27,28)(H2,25,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.70	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238288 (CHEMBL4084878) Show SMILES CN(C)c1ccc(NC(=O)Nc2ccc(cc2)-c2ccnc3[nH]nc(C)c23)cc1 Show InChI InChI=1S/C22H22N6O/c1-14-20-19(12-13-23-21(20)27-26-14)15-4-6-16(7-5-15)24-22(29)25-17-8-10-18(11-9-17)28(2)3/h4-13H,1-3H3,(H,23,26,27)(H2,24,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238313 (CHEMBL4092638) Show SMILES CCN(CC)c1ccc(NC(=O)Nc2ccc(cc2)-c2ccnc3[nH]nc(C)c23)cc1 Show InChI InChI=1S/C24H26N6O/c1-4-30(5-2)20-12-10-19(11-13-20)27-24(31)26-18-8-6-17(7-9-18)21-14-15-25-23-22(21)16(3)28-29-23/h6-15H,4-5H2,1-3H3,(H,25,28,29)(H2,26,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238283 (CHEMBL4073536) Show SMILES CCN(CC)c1cccc(NC(=O)Nc2ccc(cc2)-c2ccnc3[nH]nc(C)c23)c1 Show InChI InChI=1S/C24H26N6O/c1-4-30(5-2)20-8-6-7-19(15-20)27-24(31)26-18-11-9-17(10-12-18)21-13-14-25-23-22(21)16(3)28-29-23/h6-15H,4-5H2,1-3H3,(H,25,28,29)(H2,26,27,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238267 (CHEMBL4103890) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cccnc4)cc3)c12 Show InChI InChI=1S/C19H16N6O/c1-12-17-16(8-10-21-18(17)25-24-12)13-4-6-14(7-5-13)22-19(26)23-15-3-2-9-20-11-15/h2-11H,1H3,(H,21,24,25)(H2,22,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM21079 (1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-...) Show SMILES Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cccc3[nH]nc(N)c23)c1 Show InChI InChI=1S/C21H18FN5O/c1-12-5-10-16(22)18(11-12)25-21(28)24-14-8-6-13(7-9-14)15-3-2-4-17-19(15)20(23)27-26-17/h2-11H,1H3,(H3,23,26,27)(H2,24,25,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238323 (CHEMBL4104034) Show SMILES CN1CCN(CC1)c1cccc(NC(=O)Nc2ccc(cc2)-c2ccnc3[nH]nc(C)c23)c1 Show InChI InChI=1S/C25H27N7O/c1-17-23-22(10-11-26-24(23)30-29-17)18-6-8-19(9-7-18)27-25(33)28-20-4-3-5-21(16-20)32-14-12-31(2)13-15-32/h3-11,16H,12-15H2,1-2H3,(H,26,29,30)(H2,27,28,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238305 (CHEMBL4071160) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4ccc5ccccc5c4)cc3)c12 Show InChI InChI=1S/C24H19N5O/c1-15-22-21(12-13-25-23(22)29-28-15)17-7-9-19(10-8-17)26-24(30)27-20-11-6-16-4-2-3-5-18(16)14-20/h2-14H,1H3,(H,25,28,29)(H2,26,27,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238271 (CHEMBL4085962) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4ccccn4)cc3)c12 Show InChI InChI=1S/C19H16N6O/c1-12-17-15(9-11-21-18(17)25-24-12)13-5-7-14(8-6-13)22-19(26)23-16-4-2-3-10-20-16/h2-11H,1H3,(H,21,24,25)(H2,20,22,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238268 (CHEMBL4091975) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cnc5ccccc5c4)cc3)c12 Show InChI InChI=1S/C23H18N6O/c1-14-21-19(10-11-24-22(21)29-28-14)15-6-8-17(9-7-15)26-23(30)27-18-12-16-4-2-3-5-20(16)25-13-18/h2-13H,1H3,(H,24,28,29)(H2,26,27,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238299 (CHEMBL4074518) Show SMILES CCc1cccc(NC(=O)Nc2ccc(cc2)-c2ccnc3[nH]nc(C)c23)c1 Show InChI InChI=1S/C22H21N5O/c1-3-15-5-4-6-18(13-15)25-22(28)24-17-9-7-16(8-10-17)19-11-12-23-21-20(19)14(2)26-27-21/h4-13H,3H2,1-2H3,(H,23,26,27)(H2,24,25,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238307 (CHEMBL4101428) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)NCCCc4ccccc4)cc3)c12 Show InChI InChI=1S/C23H23N5O/c1-16-21-20(13-15-24-22(21)28-27-16)18-9-11-19(12-10-18)26-23(29)25-14-5-8-17-6-3-2-4-7-17/h2-4,6-7,9-13,15H,5,8,14H2,1H3,(H,24,27,28)(H2,25,26,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238301 (CHEMBL4071997) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)NCc4cccs4)cc3)c12 Show InChI InChI=1S/C19H17N5OS/c1-12-17-16(8-9-20-18(17)24-23-12)13-4-6-14(7-5-13)22-19(25)21-11-15-3-2-10-26-15/h2-10H,11H2,1H3,(H,20,23,24)(H2,21,22,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238298 (CHEMBL4074755) Show SMILES CCCCCCNC(=O)Nc1ccc(cc1)-c1ccnc2[nH]nc(C)c12 Show InChI InChI=1S/C20H25N5O/c1-3-4-5-6-12-22-20(26)23-16-9-7-15(8-10-16)17-11-13-21-19-18(17)14(2)24-25-19/h7-11,13H,3-6,12H2,1-2H3,(H,21,24,25)(H2,22,23,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238300 (CHEMBL4059958) Show SMILES CCc1cccc(NC(=O)Nc2ccc(cc2)-c2ccnc3[nH]nc(CO)c23)c1 Show InChI InChI=1S/C22H21N5O2/c1-2-14-4-3-5-17(12-14)25-22(29)24-16-8-6-15(7-9-16)18-10-11-23-21-20(18)19(13-28)26-27-21/h3-12,28H,2,13H2,1H3,(H,23,26,27)(H2,24,25,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238308 (CHEMBL4103605) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)c12 Show InChI InChI=1S/C21H19N5O/c1-13-4-3-5-17(12-13)24-21(27)23-16-8-6-15(7-9-16)18-10-11-22-20-19(18)14(2)25-26-20/h3-12H,1-2H3,(H,22,25,26)(H2,23,24,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM13530 (4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1 Show InChI InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238329 (CHEMBL4078084) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)NCc4ccco4)cc3)c12 Show InChI InChI=1S/C19H17N5O2/c1-12-17-16(8-9-20-18(17)24-23-12)13-4-6-14(7-5-13)22-19(25)21-11-15-3-2-10-26-15/h2-10H,11H2,1H3,(H,20,23,24)(H2,21,22,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238286 (CHEMBL4088552) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4ccc(C)cc4)cc3)c12 Show InChI InChI=1S/C21H19N5O/c1-13-3-7-16(8-4-13)23-21(27)24-17-9-5-15(6-10-17)18-11-12-22-20-19(18)14(2)25-26-20/h3-12H,1-2H3,(H,22,25,26)(H2,23,24,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50238272 (CHEMBL4072731) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4ccc(N5CCOCC5)c(C)c4)cc3)c12 Show InChI InChI=1S/C25H26N6O2/c1-16-15-20(7-8-22(16)31-11-13-33-14-12-31)28-25(32)27-19-5-3-18(4-6-19)21-9-10-26-24-23(21)17(2)29-30-24/h3-10,15H,11-14H2,1-2H3,(H,26,29,30)(H2,27,28,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human GST-tagged FLT4 (800 to 1297 residues) expressed in baculovirus by ELISA				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238297 (CHEMBL4092765) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)NCc4ccccn4)cc3)c12 Show InChI InChI=1S/C20H18N6O/c1-13-18-17(9-11-22-19(18)26-25-13)14-5-7-15(8-6-14)24-20(27)23-12-16-4-2-3-10-21-16/h2-11H,12H2,1H3,(H,22,25,26)(H2,23,24,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238310 (CHEMBL4100492) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)NCCc4ccccc4)cc3)c12 Show InChI InChI=1S/C22H21N5O/c1-15-20-19(12-14-23-21(20)27-26-15)17-7-9-18(10-8-17)25-22(28)24-13-11-16-5-3-2-4-6-16/h2-10,12,14H,11,13H2,1H3,(H,23,26,27)(H2,24,25,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238328 (CHEMBL4063368) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)NC4Cc5ccccc5C4)cc3)c12 Show InChI InChI=1S/C23H21N5O/c1-14-21-20(10-11-24-22(21)28-27-14)15-6-8-18(9-7-15)25-23(29)26-19-12-16-4-2-3-5-17(16)13-19/h2-11,19H,12-13H2,1H3,(H,24,27,28)(H2,25,26,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238290 (CHEMBL4064941) Show SMILES CN(C)c1cccc(NC(=O)Nc2ccc(cc2)-c2ccnc3[nH]nc(C)c23)c1 Show InChI InChI=1S/C22H22N6O/c1-14-20-19(11-12-23-21(20)27-26-14)15-7-9-16(10-8-15)24-22(29)25-17-5-4-6-18(13-17)28(2)3/h4-13H,1-3H3,(H,23,26,27)(H2,24,25,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238289 (CHEMBL4083050) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2ccnc3[nH]nc(CO)c23)c1 Show InChI InChI=1S/C21H19N5O2/c1-13-3-2-4-16(11-13)24-21(28)23-15-7-5-14(6-8-15)17-9-10-22-20-19(17)18(12-27)25-26-20/h2-11,27H,12H2,1H3,(H,22,25,26)(H2,23,24,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238293 (CHEMBL4074713) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)c12 Show InChI InChI=1S/C21H18FN5O/c1-12-3-8-17(22)18(11-12)25-21(28)24-15-6-4-14(5-7-15)16-9-10-23-20-19(16)13(2)26-27-20/h3-11H,1-2H3,(H,23,26,27)(H2,24,25,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238295 (CHEMBL4099718) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cccc5ccccc45)cc3)c12 Show InChI InChI=1S/C24H19N5O/c1-15-22-20(13-14-25-23(22)29-28-15)17-9-11-18(12-10-17)26-24(30)27-21-8-4-6-16-5-2-3-7-19(16)21/h2-14H,1H3,(H,25,28,29)(H2,26,27,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238302 (CHEMBL4065800) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4cccc(c4)C(F)(F)F)cc3)c12 Show InChI InChI=1S/C21H16F3N5O/c1-12-18-17(9-10-25-19(18)29-28-12)13-5-7-15(8-6-13)26-20(30)27-16-4-2-3-14(11-16)21(22,23)24/h2-11H,1H3,(H,25,28,29)(H2,26,27,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238318 (CHEMBL4085010) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4ccn[nH]4)cc3)c12 Show InChI InChI=1S/C17H15N7O/c1-10-15-13(6-8-18-16(15)24-22-10)11-2-4-12(5-3-11)20-17(25)21-14-7-9-19-23-14/h2-9H,1H3,(H,18,22,24)(H3,19,20,21,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238305 (CHEMBL4071160) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)Nc4ccc5ccccc5c4)cc3)c12 Show InChI InChI=1S/C24H19N5O/c1-15-22-21(12-13-25-23(22)29-28-15)17-7-9-19(10-8-17)26-24(30)27-20-11-6-16-4-2-3-5-18(16)14-20/h2-14H,1H3,(H,25,28,29)(H2,26,27,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	124	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238311 (CHEMBL4066302) Show SMILES CN1CCN(CC1)c1ccc(NC(=O)Nc2ccc(cc2)-c2ccnc3[nH]nc(C)c23)cc1C Show InChI InChI=1S/C26H29N7O/c1-17-16-21(8-9-23(17)33-14-12-32(3)13-15-33)29-26(34)28-20-6-4-19(5-7-20)22-10-11-27-25-24(22)18(2)30-31-25/h4-11,16H,12-15H2,1-3H3,(H,27,30,31)(H2,28,29,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	127	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238281 (CHEMBL4074745) Show SMILES Cc1n[nH]c2nccc(-c3ccc(NC(=O)NCCCCc4ccccc4)cc3)c12 Show InChI InChI=1S/C24H25N5O/c1-17-22-21(14-16-25-23(22)29-28-17)19-10-12-20(13-11-19)27-24(30)26-15-6-5-9-18-7-3-2-4-8-18/h2-4,7-8,10-14,16H,5-6,9,15H2,1H3,(H,25,28,29)(H2,26,27,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	135	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair

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