BindingDB PrimarySearch

Found 15 hits Enz. Inhib. hit(s) with all data for entry = 50036488
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50007422 ((+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a	n/a
VA Medical Center Curated by ChEMBL					Assay Description Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cells				J Med Chem 39: 850-9 (1996) Article DOI: 10.1021/jm950447w BindingDB Entry DOI: 10.7270/Q2XG9RT3
VA Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a
VA Medical Center Curated by ChEMBL					Assay Description Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cells				J Med Chem 39: 850-9 (1996) Article DOI: 10.1021/jm950447w BindingDB Entry DOI: 10.7270/Q2XG9RT3
VA Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50004822 ((R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine...) Show SMILES Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a
VA Medical Center Curated by ChEMBL					Assay Description Equilibrium dissociation constant against recombinant Dopamine receptor D2A expressed in COS7 cells				J Med Chem 39: 850-9 (1996) Article DOI: 10.1021/jm950447w BindingDB Entry DOI: 10.7270/Q2XG9RT3
VA Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a
VA Medical Center Curated by ChEMBL					Assay Description Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cells				J Med Chem 39: 850-9 (1996) Article DOI: 10.1021/jm950447w BindingDB Entry DOI: 10.7270/Q2XG9RT3
VA Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50029050 ((-)-(R)-epinephrine \| (-)-3,4-dihydroxy-alpha-((me...) Show SMILES CNC[C@H](O)c1ccc(O)c(O)c1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a
VA Medical Center Curated by ChEMBL					Assay Description Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cells				J Med Chem 39: 850-9 (1996) Article DOI: 10.1021/jm950447w BindingDB Entry DOI: 10.7270/Q2XG9RT3
VA Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE \| 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a
VA Medical Center Curated by ChEMBL					Assay Description Equilibrium dissociation constant against recombinant Dopamine receptor D2A expressed in COS7 cells				J Med Chem 39: 850-9 (1996) Article DOI: 10.1021/jm950447w BindingDB Entry DOI: 10.7270/Q2XG9RT3
VA Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50049796 ((S)-6-Chloro-7,8-dihydroxy-1-(4-hydroxy-phenyl)-2,...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	1.82E+3	n/a	n/a	n/a	n/a	n/a
VA Medical Center Curated by ChEMBL					Assay Description Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cells				J Med Chem 39: 850-9 (1996) Article DOI: 10.1021/jm950447w BindingDB Entry DOI: 10.7270/Q2XG9RT3
VA Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50004921 ((R)-3-Allyl-6-bromo-7,8-dihydroxy-1-phenyl-2,3,4,5...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	384	n/a	n/a	n/a	n/a	n/a
VA Medical Center Curated by ChEMBL					Assay Description Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cells				J Med Chem 39: 850-9 (1996) Article DOI: 10.1021/jm950447w BindingDB Entry DOI: 10.7270/Q2XG9RT3
VA Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM10755 (14C-5-hydroxy tryptamine creatinine disulfate \| 2-...) Show SMILES NCCc1c[nH]c2ccc(O)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	9.69E+3	n/a	n/a	n/a	n/a	n/a
VA Medical Center Curated by ChEMBL					Assay Description Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cells				J Med Chem 39: 850-9 (1996) Article DOI: 10.1021/jm950447w BindingDB Entry DOI: 10.7270/Q2XG9RT3
VA Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM55121 (3-HYDROXYTYRAMINE HYDROCHLORIDE \| 4-(2-aminoethyl)...) Show SMILES NCCc1ccc(O)c(O)c1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a
VA Medical Center Curated by ChEMBL					Assay Description Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cells				J Med Chem 39: 850-9 (1996) Article DOI: 10.1021/jm950447w BindingDB Entry DOI: 10.7270/Q2XG9RT3
VA Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50007422 ((+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a
VA Medical Center Curated by ChEMBL					Assay Description Equilibrium dissociation constant against recombinant Dopamine receptor D2A expressed in COS7 cells				J Med Chem 39: 850-9 (1996) Article DOI: 10.1021/jm950447w BindingDB Entry DOI: 10.7270/Q2XG9RT3
VA Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50025206 ((6,7-Dihydroxy-1,2,3,4-tetrahydro-naphthalen-2-yl)...) Show SMILES C[NH+](C)C1CCc2cc(O)c(O)cc2C1 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a
VA Medical Center Curated by ChEMBL					Assay Description Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cells				J Med Chem 39: 850-9 (1996) Article DOI: 10.1021/jm950447w BindingDB Entry DOI: 10.7270/Q2XG9RT3
VA Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50004822 ((R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine...) Show SMILES Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a
VA Medical Center Curated by ChEMBL					Assay Description Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cells				J Med Chem 39: 850-9 (1996) Article DOI: 10.1021/jm950447w BindingDB Entry DOI: 10.7270/Q2XG9RT3
VA Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a
VA Medical Center Curated by ChEMBL					Assay Description Equilibrium dissociation constant against recombinant Dopamine receptor D2A expressed in COS7 cells				J Med Chem 39: 850-9 (1996) Article DOI: 10.1021/jm950447w BindingDB Entry DOI: 10.7270/Q2XG9RT3
VA Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50029051 ((-)-arterenol \| (-)-noradrenaline \| (-)-norepineph...) Show SMILES NC[C@H](O)c1ccc(O)c(O)c1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a
VA Medical Center Curated by ChEMBL					Assay Description Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cells				J Med Chem 39: 850-9 (1996) Article DOI: 10.1021/jm950447w BindingDB Entry DOI: 10.7270/Q2XG9RT3
VA Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair