BindingDB PrimarySearch

BDBM60917 9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid::9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;mesylic acid::9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid::FENOLDOPAM::FENOLDOPAM MESYLATE::MLS001401388::SMR000469190::cid_49659

SMILES: Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12

InChI Key: InChIKey=TVURRHSHRRELCG-UHFFFAOYSA-N

Data: 20 KI 8 IC50 5 Kd 5 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 38 hits for monomerid = 60917
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(1A) dopamine receptor (RAT)	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PDB	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity against Dopamine receptor D1 in rat striatal membranes using [3H]SCH-23390				Citation and Details BindingDB Entry DOI: 10.7270/Q2930WC4
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
DRD2 (CANINE)	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Nature 350: 610-4 (1991) Article DOI: 10.1038/350610a0 BindingDB Entry DOI: 10.7270/Q24T6GVD
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]fenoldopam from Dopamine receptor D1 of rat striatum membranes				J Med Chem 29: 1904-12 (1986) BindingDB Entry DOI: 10.7270/Q2TQ623R
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Dopamine D1B (RAT)	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 88: 7491-5 (1991) Article DOI: 10.1073/pnas.88.17.7491 BindingDB Entry DOI: 10.7270/Q2DB80B9
Duke University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars		13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity against Dopamine receptor D2 in rat striatal membranes using [3H]spiperone				Citation and Details BindingDB Entry DOI: 10.7270/Q2930WC4
TBA					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Nature 350: 614-9 (1991) Article DOI: 10.1038/350614a0 BindingDB Entry DOI: 10.7270/Q2NV9GQR
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 259: 323-9 (1991) BindingDB Entry DOI: 10.7270/Q2Z899WV
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by PDSP K_i Database									Proc Natl Acad Sci U S A 88: 7491-5 (1991) Article DOI: 10.1073/pnas.88.17.7491 BindingDB Entry DOI: 10.7270/Q2DB80B9
Duke University Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
ADRA2C (OK)	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 259: 323-9 (1991) BindingDB Entry DOI: 10.7270/Q2Z899WV
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Nature 350: 614-9 (1991) Article DOI: 10.1038/350614a0 BindingDB Entry DOI: 10.7270/Q2NV9GQR
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenosine receptor A2b (Rattus norvegicus)	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound was tested for its binding affinity against Alpha-2 adrenergic receptor				Citation and Details BindingDB Entry DOI: 10.7270/Q2930WC4
TBA					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas at Austin Curated by ChEMBL					Assay Description Affinity towards Dopamine receptor D1				J Med Chem 41: 4385-99 (1998) Article DOI: 10.1021/jm9800292 BindingDB Entry DOI: 10.7270/Q2R21227
University of Texas at Austin Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Adrenergic receptor alpha-2 (NEONATAL RAT)	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Nebraska Curated by PDSP K_i Database									J Pharmacol Exp Ther 259: 323-9 (1991) BindingDB Entry DOI: 10.7270/Q2Z899WV
University of Nebraska Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Adrenergic receptor alpha-1 (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank	151	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compound was tested for its binding affinity against Alpha-1 adrenergic receptor				Citation and Details BindingDB Entry DOI: 10.7270/Q2930WC4
TBA					More data for this Ligand-Target Pair
DRD2 (CANINE)	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	321	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Nature 350: 610-4 (1991) Article DOI: 10.1038/350610a0 BindingDB Entry DOI: 10.7270/Q24T6GVD
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	790	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for inhibition of [3H]spiroperidol binding against Dopamine receptor D2				J Med Chem 29: 1904-12 (1986) BindingDB Entry DOI: 10.7270/Q2TQ623R
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Nature 350: 614-9 (1991) Article DOI: 10.1038/350614a0 BindingDB Entry DOI: 10.7270/Q2NV9GQR
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas at Austin Curated by ChEMBL					Assay Description Affinity towards Dopamine receptor D2				J Med Chem 41: 4385-99 (1998) Article DOI: 10.1021/jm9800292 BindingDB Entry DOI: 10.7270/Q2R21227
University of Texas at Austin Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	1.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Toronto Curated by PDSP K_i Database									Nature 350: 614-9 (1991) Article DOI: 10.1038/350614a0 BindingDB Entry DOI: 10.7270/Q2NV9GQR
University of Toronto Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone Lysine Demethylase (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	1.92E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Non-competitive inhibition of JMJD2E relative to alpha-ketoglutarate				Bioorg Med Chem 19: 3625-36 (2011) Article DOI: 10.1016/j.bmc.2011.01.046 BindingDB Entry DOI: 10.7270/Q23X870S
University of Copenhagen Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a
ShanghaiTech University Curated by ChEMBL					Assay Description Agonist activity at human dopamine D1 receptor expressed in CHOK1 cells assessed as assessed as increase in beta-arrestin-2 recruitment after 60 mins...				J Med Chem 61: 9841-9878 (2018) Article DOI: 10.1021/acs.jmedchem.8b00435
ShanghaiTech University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Canalicular multispecific organic anion transporter 1 (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...				Toxicol Sci 136: 216-41 (2013) BindingDB Entry DOI: 10.7270/Q2JM2D2D
Amgen Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Multidrug resistance-associated protein 4 (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...				Toxicol Sci 136: 216-41 (2013) BindingDB Entry DOI: 10.7270/Q2JM2D2D
Amgen Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Canalicular multispecific organic anion transporter 2 (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...				Toxicol Sci 136: 216-41 (2013) BindingDB Entry DOI: 10.7270/Q2JM2D2D
Amgen Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Bile salt export pump (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc Curated by ChEMBL					Assay Description Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...				Toxicol Sci 136: 216-41 (2013) BindingDB Entry DOI: 10.7270/Q2JM2D2D
Amgen Inc Curated by ChEMBL					More data for this Ligand-Target Pair
Bile salt export pump (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...				Drug Metab Dispos 40: 2332-41 (2012) Article DOI: 10.1124/dmd.112.047068 BindingDB Entry DOI: 10.7270/Q2ZP488M
AstraZeneca Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a
University of Texas Curated by ChEMBL					Assay Description In vitro affinity at mutant D2 receptor (S194A) in C6 (glioma) cell membranes.				J Med Chem 43: 3005-19 (2000) BindingDB Entry DOI: 10.7270/Q24J0FS2
University of Texas Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a
VA Medical Center Curated by ChEMBL					Assay Description Equilibrium dissociation constant against recombinant Dopamine receptor D1A expressed in COS7 cells				J Med Chem 39: 850-9 (1996) Article DOI: 10.1021/jm950447w BindingDB Entry DOI: 10.7270/Q2XG9RT3
VA Medical Center Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a
University of Texas Curated by ChEMBL					Assay Description In vitro affinity at mutant D2 receptor (S197A) in C6 (glioma) cell membranes.				J Med Chem 43: 3005-19 (2000) BindingDB Entry DOI: 10.7270/Q24J0FS2
University of Texas Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	DrugBank PDB Article PubMed	n/a	n/a	n/a	n/a	2.80	n/a	n/a	n/a	n/a
ShanghaiTech University Curated by ChEMBL					Assay Description Agonist activity at human dopamine D1 receptor expressed in CHOK1 cells assessed as reversal of Ro 20-1724 mediated decrease in cAMP accumulation aft...				J Med Chem 61: 9841-9878 (2018) Article DOI: 10.1021/acs.jmedchem.8b00435
ShanghaiTech University Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a
University of Texas Curated by ChEMBL					Assay Description In vitro affinity at mutant D2 receptor (S194A) in C6 (glioma) cell membranes.				J Med Chem 43: 3005-19 (2000) BindingDB Entry DOI: 10.7270/Q24J0FS2
University of Texas Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PDB PubMed	n/a	n/a	n/a	n/a	57	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Dopamine receptor D1 agonist efficacy was measured with stimulation of dopamine-sensitive rat adenylate cyclase in caudate membranes				J Med Chem 30: 1166-76 (1987) BindingDB Entry DOI: 10.7270/Q2028QJ6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
D(2) dopamine receptor (BOVINE)	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Displacement of [3H]-spiroperidol from homogenized bovine pituitary Dopamine receptor D2				J Med Chem 30: 1166-76 (1987) BindingDB Entry DOI: 10.7270/Q2028QJ6
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
G-protein subunit alpha-16 (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PCBioAssay	n/a	n/a	>2.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2QZ28KG
					More data for this Ligand-Target Pair
trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q24748HT
					More data for this Ligand-Target Pair
trace amine-associated receptor 1 (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PCBioAssay	n/a	n/a	8.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q280517J
					More data for this Ligand-Target Pair
G-protein subunit alpha-16 (Homo sapiens (Human))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>2.99E+4	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay									PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2CN72J7
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM60917 (9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro...) Show SMILES Oc1ccc(cc1)C1CNCCc2c(Cl)c(O)c(O)cc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a
University of Texas Curated by ChEMBL					Assay Description In vitro affinity at wild type Dopamine receptor D2 on C6 (glioma) cell membranes.				J Med Chem 43: 3005-19 (2000) BindingDB Entry DOI: 10.7270/Q24J0FS2
University of Texas Curated by ChEMBL					More data for this Ligand-Target Pair